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Priorities for hearing loss prevention and estimates of global cause-specific burdens of hearing loss: a systematic rapid review.
Prasad K, Borre ED, Dillard LK, Ayer A, Der C, Bainbridge KE, McMahon CM, Tucci DL, Wilson BS, Schmidler GDS, Saunders J. Prasad K, et al. Lancet Glob Health. 2024 Feb;12(2):e217-e225. doi: 10.1016/S2214-109X(23)00514-4. Lancet Glob Health. 2024. PMID: 38245112 Free article.
FINDINGS: An estimated 257.3 million people per year are exposed to these preventable causes of hearing loss, leading to an estimated 33.8 million new cases of hearing loss worldwide per year. ...Prevention of these conditions should be a global health priority. FUN …
FINDINGS: An estimated 257.3 million people per year are exposed to these preventable causes of hearing loss, leading to an estimated …
Hear and Now: Ongoing Clinical Trials to Prevent Drug-Induced Hearing Loss.
Lee J, Fernandez K, Cunningham LL. Lee J, et al. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:211-230. doi: 10.1146/annurev-pharmtox-033123-114106. Epub 2023 Aug 10. Annu Rev Pharmacol Toxicol. 2024. PMID: 37562496 Free article. Review.
At least 17 clinical trials evaluating 10 therapeutics are currently underway for therapies aimed at preventing aminoglycoside- and/or cisplatin-induced ototoxicity. This review describes the preclinical and clinical development of each of these approaches, provides update …
At least 17 clinical trials evaluating 10 therapeutics are currently underway for therapies aimed at preventing aminoglycoside- and/o …
Prevalence of hearing loss in college students: a meta-analysis.
Kornisch M, Barton A, Park H, Lowe R, Ikuta T. Kornisch M, et al. Front Neurosci. 2024 Jan 5;17:1282829. doi: 10.3389/fnins.2023.1282829. eCollection 2023. Front Neurosci. 2024. PMID: 38249585 Free PMC article.
Therefore, implementing a hearing conservation program may be advised for colleges and universities to help prevent hearing loss in students, particularly for collegiate musicians. ...
Therefore, implementing a hearing conservation program may be advised for colleges and universities to help prevent hearing loss in s …
Age-related hearing loss: An updated and comprehensive review of the interventions.
Tavanai E, Rahimi V, Khalili ME, Falahzadeh S, Motasaddi Zarandy M, Mohammadkhani G. Tavanai E, et al. Iran J Basic Med Sci. 2024;27(3):256-269. doi: 10.22038/IJBMS.2023.72863.15849. Iran J Basic Med Sci. 2024. PMID: 38333758 Free PMC article. Review.
Aging causes progressive degenerative changes in many organs, particularly the auditory system. Several attempts have been conducted to investigate preventive and therapeutic strategy/strategies for age-related auditory dysfunction, such as maintaining a healthy lifestyle …
Aging causes progressive degenerative changes in many organs, particularly the auditory system. Several attempts have been conducted to inve …
Noise-induced hearing loss in the pre-industrial era: early contributions in De Morbis Artificum by Bernardino Ramazzini (1633-1714).
Paladino ME, Belingheri M, Mazzagatti R, Riva MA. Paladino ME, et al. J Laryngol Otol. 2024 Jan;138(1):7-9. doi: 10.1017/S0022215123001457. Epub 2023 Aug 30. J Laryngol Otol. 2024. PMID: 37646190 Free PMC article. Review.
He also seemed to describe tinnitus. He further suggested the use of earplugs as a preventive measure for these classes of workers. Ramazzini's anatomical and pathological knowledge appears to be based on ancient authors; he did not discuss contemporaneous medical authors' …
He also seemed to describe tinnitus. He further suggested the use of earplugs as a preventive measure for these classes of workers. R …
Cardiovascular Risk Factors, Cerebral Small Vessel Disease, and Subsequent Risk of Stroke in Patients with Idiopathic Sudden Sensorineural Hearing Loss: Systematic Review and Meta-Analyses of the Current Literature.
Oussoren FK, Schermer TR, van Leeuwen RB, Bruintjes TD. Oussoren FK, et al. Audiol Neurootol. 2024;29(1):1-29. doi: 10.1159/000530686. Epub 2023 Aug 9. Audiol Neurootol. 2024. PMID: 37557093 Free PMC article.
Prospective studies with larger study populations are needed to confirm the associations between generalized cardiovascular disease and iSSNHL and to assess whether these patients benefit from cardiovascular risk management to prevent future cardiovascular and cerebrovascu …
Prospective studies with larger study populations are needed to confirm the associations between generalized cardiovascular disease and iSSN …
Congenital Deafness and Deaf-Mutism: A Historical Perspective.
Cozza A, Di Pasquale Fiasca VM, Martini A. Cozza A, et al. Children (Basel). 2023 Dec 30;11(1):51. doi: 10.3390/children11010051. Children (Basel). 2023. PMID: 38255364 Free PMC article. Review.
Therefore, early detection and prompt treatment are of utmost importance in preventing the unwanted sequel of hearing loss on normal language development. ...
Therefore, early detection and prompt treatment are of utmost importance in preventing the unwanted sequel of hearing loss on normal …
The Role of Fibrinogen, Homocysteine and Metabolic Syndrome's Alterations in Sudden Sensorineural Hearing Loss (SSHL): A Narrative Review.
Monzani D, Liberale C, Segato E, De Cecco F, Arietti V, Palma S, Sacchetto L, Nocini R. Monzani D, et al. Medicina (Kaunas). 2023 Nov 9;59(11):1977. doi: 10.3390/medicina59111977. Medicina (Kaunas). 2023. PMID: 38004026 Free PMC article. Review.
However, although some studies suggest a possible role for these biomarkers and MetS in the prognosis and treatment of SSHL, specific therapeutic and preventive strategies based solely on these factors have yet to be developed. ...
However, although some studies suggest a possible role for these biomarkers and MetS in the prognosis and treatment of SSHL, specific therap …
NIOSH Hearing Loss Prevention Program for Mining.
Peterson JS, Azman AS. Peterson JS, et al. Semin Hear. 2023 Jun 5;44(4):394-411. doi: 10.1055/s-0043-1769500. eCollection 2023 Nov. Semin Hear. 2023. PMID: 37818149 Free PMC article. Review.
As one of the leading health and safety organizations in the world, the National Institute for Occupational Health and Safety (NIOSH) in Pittsburgh maintains a Hearing Loss Prevention Program (HLPP) to conduct research to reduce NIHL loss among the nation's miners. ...
As one of the leading health and safety organizations in the world, the National Institute for Occupational Health and Safety (NIOSH) in Pit …
Preventing Occupational Hearing Loss: 50 Years of Research and Recommendations from the National Institute for Occupational Safety and Health.
Themann CL, Masterson EA, Peterson JS, Murphy WJ. Themann CL, et al. Semin Hear. 2023 Aug 3;44(4):351-393. doi: 10.1055/s-0043-1769499. eCollection 2023 Nov. Semin Hear. 2023. PMID: 37818146 Free PMC article. Review.
For more than 50 years, the National Institute for Occupational Safety and Health (NIOSH), part of the United States (U.S.) Centers for Disease Control and Prevention (CDC), has been actively working to reduce the effects of noise and ototoxic chemicals on worker hearing. …
For more than 50 years, the National Institute for Occupational Safety and Health (NIOSH), part of the United States (U.S.) Centers for Dise …
Workers' Compensation Costs for Occupational Hearing Loss Claims in the United States, 2009-2013.
Masterson EA, Wurzelbacher SJ, Bushnell PT, Tseng CY. Masterson EA, et al. Semin Hear. 2023 Jun 22;44(4):412-436. doi: 10.1055/s-0043-1769587. eCollection 2023 Nov. Semin Hear. 2023. PMID: 37818144 Free PMC article. Review.
Workers in a wide range of industry/occupation classifications need special attention to prevent OHL....
Workers in a wide range of industry/occupation classifications need special attention to prevent OHL....
Recent advances in genetic etiology of non-syndromic deafness in children.
Feng Y, Hu S, Zhao S, Chen M. Feng Y, et al. Front Neurosci. 2023 Oct 19;17:1282663. doi: 10.3389/fnins.2023.1282663. eCollection 2023. Front Neurosci. 2023. PMID: 37928735 Free PMC article. Review.
The consequences associated with hearing loss among children encompass the decline of verbal communication, linguistic skills, educational progress, social integration, cognitive aptitude, and overall well-being. Approaches to reversing or preventing genetic hearing loss a …
The consequences associated with hearing loss among children encompass the decline of verbal communication, linguistic skills, educational p …
Intratympanic injection of hydrogel nanodrug for the prevention and treatment of sensorineural hearing loss.
Zhai T, Ai P, Tang Z, He C, Chen X, Yang S, Wu N. Zhai T, et al. J Otol. 2023 Oct;18(4):235-239. doi: 10.1016/j.joto.2023.09.005. Epub 2023 Sep 19. J Otol. 2023. PMID: 37877070 Free PMC article. Review.
Safe and efficient drug delivery to the inner ear has always been the focus of prevention and treatment of sensorineural deafness. The rapid development of nanodrug delivery systems based on hydrogel has provided a new opportunity. ...
Safe and efficient drug delivery to the inner ear has always been the focus of prevention and treatment of sensorineural deafness. Th …
Deafness: from genetic architecture to gene therapy.
Petit C, Bonnet C, Safieddine S. Petit C, et al. Nat Rev Genet. 2023 Oct;24(10):665-686. doi: 10.1038/s41576-023-00597-7. Epub 2023 May 12. Nat Rev Genet. 2023. PMID: 37173518 Free article. Review.
The application of these approaches in preclinical studies over the past decade has highlighted key translational opportunities and challenges for achieving effective, safe and sustained inner-ear gene therapy to prevent or cure monogenic forms of SNHI and associated balan …
The application of these approaches in preclinical studies over the past decade has highlighted key translational opportunities and challeng …
Endothelial Dysfunction and Metabolic Disorders in Patients with Sudden Sensorineural Hearing Loss.
Cavallaro G, Pantaleo A, Pontillo V, Barbara F, Murri A, Quaranta N. Cavallaro G, et al. Medicina (Kaunas). 2023 Sep 26;59(10):1718. doi: 10.3390/medicina59101718. Medicina (Kaunas). 2023. PMID: 37893435 Free PMC article. Review.
By addressing these variables, we can deepen our comprehension of the mechanisms underlying SSNHL and potentially uncover strategies for prevention....
By addressing these variables, we can deepen our comprehension of the mechanisms underlying SSNHL and potentially uncover strategies for …
Age-related hearing loss and its potential drug candidates: a systematic review.
Hu S, Sun Q, Xu F, Jiang N, Gao J. Hu S, et al. Chin Med. 2023 Sep 20;18(1):121. doi: 10.1186/s13020-023-00825-6. Chin Med. 2023. PMID: 37730634 Free PMC article. Review.
OBJECTIVES: The goal of this review is to systematically evaluate and analyze recent statistics on the pathologic classifications, risk factors, treatment strategies, and drug candidates of ARHL, including that from traditional Chinese medicine (TCM), to provide potential new app …
OBJECTIVES: The goal of this review is to systematically evaluate and analyze recent statistics on the pathologic classifications, risk fact …
Community Perspectives on Hearing Loss in Rural Alaska.
Inglis-Jenson M, Robler SK, Gallo JJ, Ivanoff P, Ryan S, Hofstetter P, Emmett SD. Inglis-Jenson M, et al. Ear Hear. 2023 Sep-Oct 01;44(5):1078-1087. doi: 10.1097/AUD.0000000000001348. Epub 2023 Mar 24. Ear Hear. 2023. PMID: 36939709 Free PMC article. Clinical Trial.
For hearing-related health care in this region, these findings suggest localized recommendations for approaches for prevention and treatment. For community-based hearing research, this study offers an example of how qualitative methods can be used to generate ecologically …
For hearing-related health care in this region, these findings suggest localized recommendations for approaches for prevention and tr …
Progress on mechanisms of age-related hearing loss.
Yang W, Zhao X, Chai R, Fan J. Yang W, et al. Front Neurosci. 2023 Aug 30;17:1253574. doi: 10.3389/fnins.2023.1253574. eCollection 2023. Front Neurosci. 2023. PMID: 37727326 Free PMC article. Review.
The purpose of this review is to illuminate the various mechanisms underlying this age-related hearing loss, with the goal of advancing our understanding, prevention, and treatment of presbycusis....
The purpose of this review is to illuminate the various mechanisms underlying this age-related hearing loss, with the goal of advancing our …
Evidence reviews for preventing otorrhoea after surgery for hearing loss associated with OME in children: Otitis media with effusion in under 12s: Evidence review K.
[No authors listed] [No authors listed] London: National Institute for Health and Care Excellence (NICE); 2023 Aug. London: National Institute for Health and Care Excellence (NICE); 2023 Aug. PMID: 37792988 Free Books & Documents. Review.
The aim of this review is to assess the effectiveness of intraoperative or postoperative interventions at preventing otorrhoea (ear discharge) after surgery for otitis media with effusion (OME)-related hearing loss in children under 12 years. ...
The aim of this review is to assess the effectiveness of intraoperative or postoperative interventions at preventing otorrhoea (ear d …
Congenital Cytomegalovirus and Hearing Loss: The State of the Art.
Aldè M, Binda S, Primache V, Pellegrinelli L, Pariani E, Pregliasco F, Di Berardino F, Cantarella G, Ambrosetti U. Aldè M, et al. J Clin Med. 2023 Jul 3;12(13):4465. doi: 10.3390/jcm12134465. J Clin Med. 2023. PMID: 37445500 Free PMC article. Review.
Diagnosis of cCMV infection can be performed by detection of CMV DNA in urine or saliva within 2-3 weeks after birth, or later in dried blood samples on the Guthrie card. Currently, there are many controversies regarding the preventive, diagnostic, and therapeutic approach …
Diagnosis of cCMV infection can be performed by detection of CMV DNA in urine or saliva within 2-3 weeks after birth, or later in dried bloo …
Do hearing loss interventions prevent dementia?
Dawes P, Völter C. Dawes P, et al. Z Gerontol Geriatr. 2023 Jul;56(4):261-268. doi: 10.1007/s00391-023-02178-z. Epub 2023 May 4. Z Gerontol Geriatr. 2023. PMID: 37140632 Free PMC article. Review.
The Pathogenesis of Cytomegalovirus and Other Viruses Associated with Hearing Loss: Recent Updates.
Shi X, Liu X, Sun Y. Shi X, et al. Viruses. 2023 Jun 16;15(6):1385. doi: 10.3390/v15061385. Viruses. 2023. PMID: 37376684 Free PMC article. Review.
We hope to provide a detailed description of pathogenic characteristics and research progress on pathology, hearing phenotypes, possible associated mechanisms, treatment, and prevention measures. This review aims to provide diagnostic and treatment assistance to clinical w …
We hope to provide a detailed description of pathogenic characteristics and research progress on pathology, hearing phenotypes, possible ass …
Various aspects of hearing loss in newborns: A narrative review.
Al-Ani RM. Al-Ani RM. World J Clin Pediatr. 2023 Jun 9;12(3):86-96. doi: 10.5409/wjcp.v12.i3.86. eCollection 2023 Jun 9. World J Clin Pediatr. 2023. PMID: 37342452 Free PMC article. Review.
Therefore, early detection and prompt treatment are of utmost importance in preventing the unwanted sequel of hearing loss. The hearing screening program is mandatory in many nations, especially for high-risk newborns. ...
Therefore, early detection and prompt treatment are of utmost importance in preventing the unwanted sequel of hearing loss. The heari …
Research progress on the treatment and nursing of sensorineural hearing loss.
Liu F, Han B, Zhou X, Huang S, Huang J. Liu F, et al. Front Neurosci. 2023 Jun 6;17:1199946. doi: 10.3389/fnins.2023.1199946. eCollection 2023. Front Neurosci. 2023. PMID: 37346087 Free PMC article. Review.
In addition, there is a need for health education programs for the general public to raise awareness of SNHL and promote preventive measures to reduce its incidence. The ultimate goal is to ensure the sustainable development of the field of SNHL treatment and care, thus en …
In addition, there is a need for health education programs for the general public to raise awareness of SNHL and promote preventive m …
Research progress in delineating the pathological mechanisms of GJB2-related hearing loss.
Wang Y, Jin Y, Zhang Q, Xiong Y, Gu X, Zeng S, Chen W. Wang Y, et al. Front Cell Neurosci. 2023 Jun 2;17:1208406. doi: 10.3389/fncel.2023.1208406. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37333892 Free PMC article. Review.
Clarifying the pathological mechanism of GJB2-related hearing loss can help develop new prevention and treatment strategies....
Clarifying the pathological mechanism of GJB2-related hearing loss can help develop new prevention and treatment strategies....
Hearing Loss Diagnosis and Management in Adults with Intellectual and Developmental Disabilities.
Danyluk A, Jacob R. Danyluk A, et al. Adv Med. 2023 May 21;2023:6825476. doi: 10.1155/2023/6825476. eCollection 2023. Adv Med. 2023. PMID: 37251596 Free PMC article. Review.
Hearing loss is a common concern in patients with intellectual and developmental disabilities (IDD), and early detection and intervention are crucial to prevent negative impacts on communication, cognition, socialization, safety, and mental health. ...
Hearing loss is a common concern in patients with intellectual and developmental disabilities (IDD), and early detection and intervention ar …
Occupational noise exposure at sea: A socio-legal study on fish harvesters' perceptions in Newfoundland and Labrador, Canada.
Yadav OP, Shan D, Sarkar A, Moro L. Yadav OP, et al. Front Public Health. 2023 Apr 17;11:1092350. doi: 10.3389/fpubh.2023.1092350. eCollection 2023. Front Public Health. 2023. PMID: 37139364 Free PMC article. Review.
METHODS: A review of legislation and policies governing workplace noise exposure, as well as qualitative, semi-structured interviews, were conducted to assess how fish harvesters in Newfoundland and Labrador (NL) manage onboard occupational noise exposure and perceive noise-induc …
METHODS: A review of legislation and policies governing workplace noise exposure, as well as qualitative, semi-structured interviews, were c …
Antioxidant Therapy as an Effective Strategy against Noise-Induced Hearing Loss: From Experimental Models to Clinic.
Pisani A, Paciello F, Montuoro R, Rolesi R, Galli J, Fetoni AR. Pisani A, et al. Life (Basel). 2023 Apr 17;13(4):1035. doi: 10.3390/life13041035. Life (Basel). 2023. PMID: 37109564 Free PMC article. Review.
For this reason, several studies focused on the possibility to use exogenous antioxidant to prevent or attenuate noise-induce injury. Thus, several antioxidant molecules, alone or in combination with other compounds, have been tested in both experimental and clinical setti …
For this reason, several studies focused on the possibility to use exogenous antioxidant to prevent or attenuate noise-induce injury. …
The Effect of Noise Exposure on High-Frequency Hearing Loss among Chinese Workers: A Meta-Analysis.
Yang P, Xie H, Li Y, Jin K. Yang P, et al. Healthcare (Basel). 2023 Apr 10;11(8):1079. doi: 10.3390/healthcare11081079. Healthcare (Basel). 2023. PMID: 37107914 Free PMC article. Review.
This study suggests that the detection rate of HFNIHL is high in Chinese workers, the risk of HFNIHL increases rapidly when CNE reaches 90 dB(A).year, and the first 15 years of exposure to noise is a period of increasing risk. Therefore, reasonable measures for preventing
This study suggests that the detection rate of HFNIHL is high in Chinese workers, the risk of HFNIHL increases rapidly when CNE reaches 90 d …
A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss.
Tang D, Tran Y, Dawes P, Gopinath B. Tang D, et al. Antioxidants (Basel). 2023 Apr 4;12(4):878. doi: 10.3390/antiox12040878. Antioxidants (Basel). 2023. PMID: 37107253 Free PMC article. Review.
By addressing modifiable lifestyle risk factors that exacerbate oxidative stress, there may be an opportunity to prevent hearing loss. Therefore, this narrative review provides an overview of the major modifiable lifestyle risk factors associated with age-related hearing l …
By addressing modifiable lifestyle risk factors that exacerbate oxidative stress, there may be an opportunity to prevent hearing loss …
Mitochondrial redox system: A key target of antioxidant therapy to prevent acquired sensorineural hearing loss.
Baek JI, Kim YR, Lee KY, Kim UK. Baek JI, et al. Front Pharmacol. 2023 Mar 31;14:1176881. doi: 10.3389/fphar.2023.1176881. eCollection 2023. Front Pharmacol. 2023. PMID: 37063286 Free PMC article. Review.
In this review, we will discuss the scientific possibility of developing drugs that target particular key elements of the mitochondrial redox network in prevention or treatment of noise- and ototoxic drug-induced hearing loss....
In this review, we will discuss the scientific possibility of developing drugs that target particular key elements of the mitochondrial redo …
Noise-Induced Hearing Loss.
Natarajan N, Batts S, Stankovic KM. Natarajan N, et al. J Clin Med. 2023 Mar 17;12(6):2347. doi: 10.3390/jcm12062347. J Clin Med. 2023. PMID: 36983347 Free PMC article. Review.
The diagnosis and screening of NIHL are conducted by reviewing a patient's history of noise exposure, audiograms, speech-in-noise test results, and measurements of distortion product otoacoustic emissions and auditory brainstem response. Essential aspects of decreasing the burden …
The diagnosis and screening of NIHL are conducted by reviewing a patient's history of noise exposure, audiograms, speech-in-noise test resul …
Occupational Noise-Induced Hearing Loss in Iran: A Systematic Review and Meta-Analysis.
Etemadinezhad S, Sammak Amani A, Moosazadeh M, Rahimlou M, Samaei SE. Etemadinezhad S, et al. Iran J Public Health. 2023 Feb;52(2):278-289. doi: 10.18502/ijph.v52i2.11881. Iran J Public Health. 2023. PMID: 37089160 Free PMC article. Review.
The results also highlighted the urgent need for taking appropriate preventive and control measures in the work-places; particularly by encouraging the employers and health-related policymakers to focus on preventive noise control techniques along with administrativ …
The results also highlighted the urgent need for taking appropriate preventive and control measures in the work-places; particularly …
Redox Imbalance as a Common Pathogenic Factor Linking Hearing Loss and Cognitive Decline.
Paciello F, Ripoli C, Fetoni AR, Grassi C. Paciello F, et al. Antioxidants (Basel). 2023 Jan 31;12(2):332. doi: 10.3390/antiox12020332. Antioxidants (Basel). 2023. PMID: 36829891 Free PMC article. Review.
As such, antioxidant therapy seems to be a promising approach to prevent and/or counteract both sensory and cognitive neurodegeneration. ...
As such, antioxidant therapy seems to be a promising approach to prevent and/or counteract both sensory and cognitive neurodegenerati …
Alcohol as a risk factor for hearing loss: A systematic review and meta-analysis.
Qian P, Zhao Z, Liu S, Xin J, Liu Y, Hao Y, Wang Y, Yang L. Qian P, et al. PLoS One. 2023 Jan 20;18(1):e0280641. doi: 10.1371/journal.pone.0280641. eCollection 2023. PLoS One. 2023. PMID: 36662896 Free PMC article.
Drinkers were at a higher risk than non-drinkers. Drinking limitations may be useful for preventing hearing loss....
Drinkers were at a higher risk than non-drinkers. Drinking limitations may be useful for preventing hearing loss....
Environmental Factors for Hearing Loss and Middle Ear Disease in Alaska Native Children and Adolescents: A Cross-Sectional Analysis from a Cluster Randomized Trial.
Hicks KL, Robler SK, Platt A, Morton SN, Egger JR, Emmett SD. Hicks KL, et al. Ear Hear. 2023 Jan-Feb 01;44(1):2-9. doi: 10.1097/AUD.0000000000001265. Epub 2022 Aug 23. Ear Hear. 2023. PMID: 35998103 Free PMC article. Clinical Trial.
OBJECTIVES: Infection-related childhood hearing loss is one of the few preventable chronic health conditions that can affect a child's lifelong trajectory. ...
OBJECTIVES: Infection-related childhood hearing loss is one of the few preventable chronic health conditions that can affect a child' …
The ubiquitin-proteasome system in normal hearing and deafness.
Pouyo R, Chung K, Delacroix L, Malgrange B. Pouyo R, et al. Hear Res. 2022 Dec;426:108366. doi: 10.1016/j.heares.2021.108366. Epub 2021 Sep 29. Hear Res. 2022. PMID: 34645583 Free article. Review.
The most common outcome of protein ubiquitination is degradation by the ubiquitin-proteasome system (UPS), preventing the accumulation of misfolded, damaged, and excess proteins. ...In this review, we provide insight into the well-oiled machinery of UPS with a focus on its …
The most common outcome of protein ubiquitination is degradation by the ubiquitin-proteasome system (UPS), preventing the accumulatio …
Linking Cerebrovascular Dysfunction to Age-Related Hearing Loss and Alzheimer's Disease-Are Systemic Approaches for Diagnosis and Therapy Required?
Förster CY, Shityakov S, Scheper V, Lenarz T. Förster CY, et al. Biomolecules. 2022 Nov 19;12(11):1717. doi: 10.3390/biom12111717. Biomolecules. 2022. PMID: 36421731 Free PMC article. Review.
Finally, there are options for the treatment of ARHL by targeted neurotrophic factor supplementation to the cochlea to improve cognitive outcomes; they can also prevent AD development and AD-related comorbidity in the future....
Finally, there are options for the treatment of ARHL by targeted neurotrophic factor supplementation to the cochlea to improve cognitive out …
Clinical Features and Prognosis of Facial Palsy and Hearing Loss in Patients With Ramsay Hunt Syndrome.
Malhotra R, Mudey A, Agrawal I. Malhotra R, et al. Cureus. 2022 Oct 31;14(10):e30897. doi: 10.7759/cureus.30897. eCollection 2022 Oct. Cureus. 2022. PMID: 36465761 Free PMC article. Review.
The course and outcome of facial nerve palsy is determined by the early clinical picture, while the otological symptoms rely on the extent of nerve involvement. Early diagnosis and treatment go a long way in preventing these complications and increasing the chances of comp …
The course and outcome of facial nerve palsy is determined by the early clinical picture, while the otological symptoms rely on the extent o …
Impacts of impaired mitochondrial dynamics in hearing loss: Potential therapeutic targets.
Zou T, Ye B, Chen K, Zhang A, Guo D, Pan Y, Ding R, Hu H, Sun X, Xiang M. Zou T, et al. Front Neurosci. 2022 Oct 5;16:998507. doi: 10.3389/fnins.2022.998507. eCollection 2022. Front Neurosci. 2022. PMID: 36278017 Free PMC article. Review.
The impacts of impaired mitochondrial dynamics on hearing loss are discussed, and the potential of mitochondrial dynamics for the prevention and treatment of hearing loss is considered....
The impacts of impaired mitochondrial dynamics on hearing loss are discussed, and the potential of mitochondrial dynamics for the prevent
Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss.
Wu F, Sambamurti K, Sha S. Wu F, et al. J Assoc Res Otolaryngol. 2022 Oct;23(5):569-578. doi: 10.1007/s10162-022-00866-y. Epub 2022 Aug 24. J Assoc Res Otolaryngol. 2022. PMID: 36002664 Free PMC article. Review.
However, AAV transduction for gene silencing or expression to prevent or manage acquired hearing loss is limited. This review provides an overview of AAV as a leading gene delivery vector for treating genetic hearing loss in animal models. We highlight the advantages and s …
However, AAV transduction for gene silencing or expression to prevent or manage acquired hearing loss is limited. This review provide …
Considering gene therapy to protect from X-linked deafness DFNX2 and associated neurodevelopmental disorders.
Defourny J. Defourny J. Ibrain. 2022 Sep 27;8(4):431-441. doi: 10.1002/ibra.12068. eCollection 2022 Winter. Ibrain. 2022. PMID: 37786584 Free PMC article. Review.
Thus, we suggest that an AAV7-mediated delivery of Pou3f4 complementary DNA in the spiral ligament of Pou3f4 (-/y) mice could represent an attractive strategy to prevent fibrocyte degeneration and to restore normal cochlear functions and properties, including a positive en …
Thus, we suggest that an AAV7-mediated delivery of Pou3f4 complementary DNA in the spiral ligament of Pou3f4 (-/y) mice could represent an a …
Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer's Disease: A Narrative Review.
Tarawneh HY, Jayakody DMP, Sohrabi HR, Martins RN, Mulders WHAM. Tarawneh HY, et al. J Alzheimers Dis Rep. 2022 Sep 12;6(1):539-556. doi: 10.3233/ADR-220035. eCollection 2022. J Alzheimers Dis Rep. 2022. PMID: 36275417 Free PMC article. Review.
Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, prevention, and/or treatment of AD. This paper also provides insight into the current evidence for the use of hearing treatments as …
Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, …
The Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) study: International consensus on outcome measures for trials of interventions for adults with single-sided deafness.
Katiri R, Hall DA, Hoare DJ, Fackrell K, Horobin A, Hogan N, Buggy N, Van de Heyning PH, Firszt JB, Bruce IA, Kitterick PT; Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) initiative. Katiri R, et al. Trials. 2022 Sep 8;23(1):764. doi: 10.1186/s13063-022-06702-1. Trials. 2022. PMID: 36076299 Free PMC article.
Benefits and harms (outcome domains) of these interventions are until now reported inconsistently in clinical trials. Inconsistency in reporting outcome measures prevents meaningful comparisons or syntheses of trial results. The Core Rehabilitation Outcome Set for Single-S …
Benefits and harms (outcome domains) of these interventions are until now reported inconsistently in clinical trials. Inconsistency in repor …
Effect of N-acetyl-cysteine treatment on sensorineural hearing loss: a meta-analysis.
Bai X, Wang M, Niu X, Yu H, Yue JX, Sun Y. Bai X, et al. World J Otorhinolaryngol Head Neck Surg. 2022 May 12;8(3):205-212. doi: 10.1016/j.wjorl.2021.01.005. eCollection 2022 Sep. World J Otorhinolaryngol Head Neck Surg. 2022. PMID: 36159904 Free PMC article. Review.
However, NAC treatment was linked with improved patient outcomes of hearing tests in cases of sudden hearing loss, but did not prevent hearing loss induced by noise or ototoxicity. However, there is a need for better-designed studies with larger samples to further prove th …
However, NAC treatment was linked with improved patient outcomes of hearing tests in cases of sudden hearing loss, but did not prevent
Global burden of ototoxic hearing loss associated with platinum-based cancer treatment: A systematic review and meta-analysis.
Dillard LK, Lopez-Perez L, Martinez RX, Fullerton AM, Chadha S, McMahon CM. Dillard LK, et al. Cancer Epidemiol. 2022 Aug;79:102203. doi: 10.1016/j.canep.2022.102203. Epub 2022 Jun 17. Cancer Epidemiol. 2022. PMID: 35724557 Free PMC article. Review.
This can be partially achieved by implementing existing strategies focused on primary, secondary, and tertiary hearing loss prevention. Primary ototoxicity prevention via otoprotectants should be a research and policy priority....
This can be partially achieved by implementing existing strategies focused on primary, secondary, and tertiary hearing loss prevention
The Role of Genetic Variants in the Susceptibility of Noise-Induced Hearing Loss.
Chen XM, Xue XM, Yu N, Guo WW, Yuan SL, Jiang QQ, Yang SM. Chen XM, et al. Front Cell Neurosci. 2022 Jul 12;16:946206. doi: 10.3389/fncel.2022.946206. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35903368 Free PMC article. Review.
In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, intending to give insights into the further exploration of NIHL prevention and individual treatment....
In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, …
Advancements in prevention and intervention of sensorineural hearing loss.
Ren H, Hu B, Jiang G. Ren H, et al. Ther Adv Chronic Dis. 2022 Jun 27;13:20406223221104987. doi: 10.1177/20406223221104987. eCollection 2022. Ther Adv Chronic Dis. 2022. PMID: 35782345 Free PMC article. Review.
In this article, we review the recent advances about SHNL and discuss the complexities and challenges of prevention and intervention of SNHL....
In this article, we review the recent advances about SHNL and discuss the complexities and challenges of prevention and intervention …
Prevention of Noise-Induced Hearing Loss Using Investigational Medicines for the Inner Ear: Previous Trial Outcomes Should Inform Future Trial Design.
Le Prell CG. Le Prell CG. Antioxid Redox Signal. 2022 Jun;36(16-18):1171-1202. doi: 10.1089/ars.2021.0166. Epub 2021 Oct 4. Antioxid Redox Signal. 2022. PMID: 34346254 Free PMC article. Review.
Recent Advances: Advances in the mechanistic understanding of NIHL have prompted a growing number of proposed, in-progress, and completed clinical trials for possible protections against NIHL via antioxidants and other drug agents. Thirty-one clinical trials evaluating prevent
Recent Advances: Advances in the mechanistic understanding of NIHL have prompted a growing number of proposed, in-progress, and completed cl …
Unexpected Consequences of Noise-Induced Hearing Loss: Impaired Hippocampal Neurogenesis, Memory, and Stress.
Manohar S, Chen GD, Ding D, Liu L, Wang J, Chen YC, Chen L, Salvi R. Manohar S, et al. Front Integr Neurosci. 2022 May 10;16:871223. doi: 10.3389/fnint.2022.871223. eCollection 2022. Front Integr Neurosci. 2022. PMID: 35619926 Free PMC article. Review.
These experimental results may provide new insights on why hearing loss is a risk factor for cognitive decline and suggest methods for preventing this decline....
These experimental results may provide new insights on why hearing loss is a risk factor for cognitive decline and suggest methods for pr
Immune-Mediated Association Between Celiac Disease and Sensorineural Hearing Loss: A Systematic Narrative Review.
De Luca P, Scarpa A, Ralli M, Tassone D, Cassandro C, Simone M, de Campora L, Camaioni A. De Luca P, et al. Turk J Gastroenterol. 2022 Apr;33(4):273-279. doi: 10.5152/tjg.2022.21554. Turk J Gastroenterol. 2022. PMID: 35550535 Free PMC article.
Despite existing literature not clarifying the link between celiac disease and sensorineural hearing loss, some authors proposed hearing screening in younger patients with celiac disease, to prevent the behavioral, cognitive, and sensorimotor impairment of hearing loss. .. …
Despite existing literature not clarifying the link between celiac disease and sensorineural hearing loss, some authors proposed hearing scr …
The alpha9alpha10 nicotinic acetylcholine receptor: a compelling drug target for hearing loss?
Elgoyhen AB. Elgoyhen AB. Expert Opin Ther Targets. 2022 Mar;26(3):291-302. doi: 10.1080/14728222.2022.2047931. Epub 2022 Mar 7. Expert Opin Ther Targets. 2022. PMID: 35225139 Free PMC article. Review.
INTRODUCTION: Hearing loss is a major health problem, impacting education, communication, interpersonal relationships, and mental health. Drugs that prevent or restore hearing are lacking and hence novel drug targets are sought. There is the possibility of targeting the al …
INTRODUCTION: Hearing loss is a major health problem, impacting education, communication, interpersonal relationships, and mental health. Dr …
Hearing Loss and Cognition: What We Know and Where We Need to Go.
Powell DS, Oh ES, Reed NS, Lin FR, Deal JA. Powell DS, et al. Front Aging Neurosci. 2022 Feb 28;13:769405. doi: 10.3389/fnagi.2021.769405. eCollection 2021. Front Aging Neurosci. 2022. PMID: 35295208 Free PMC article. Review.
These selected research priorities include examination of the causal mechanism, measurement of co-existing hearing loss and cognitive impairment and determination of any bias in testing, potential for managing hearing loss for prevention of dementia and cognitive decline, …
These selected research priorities include examination of the causal mechanism, measurement of co-existing hearing loss and cognitive impair …
Effect of N-acetyl-cysteine in prevention of noise-induced hearing loss: a systematic review and meta-analysis of randomized controlled trials.
Chang PH, Liu CW, Hung SH, Kang YN. Chang PH, et al. Arch Med Sci. 2021 Mar 21;18(6):1535-1541. doi: 10.5114/aoms/109126. eCollection 2022. Arch Med Sci. 2021. PMID: 36457967 Free PMC article. Review.
Although multiple factors lead to noise-induced hearing loss, prevention and protection strategies remain limited. Studies in the past decade have employed antioxidants, especially N-acetyl-cysteine, to prevent noise-induced hearing loss. Therefore, this systematic …
Although multiple factors lead to noise-induced hearing loss, prevention and protection strategies remain limited. Studies in the pas …
Mechanism and Protection of Radiotherapy Induced Sensorineural Hearing Loss for Head and Neck Cancer.
Shi W, Hou X, Bao X, Hou W, Jiang X, Ma L, Jiang X, Dong L. Shi W, et al. Biomed Res Int. 2021 Dec 21;2021:3548706. doi: 10.1155/2021/3548706. eCollection 2021. Biomed Res Int. 2021. PMID: 34970625 Free PMC article. Review.
The literature was examined for the possible mechanism and preventive measures of sensorineural hearing loss induced by radiotherapy. ...At present, the occurrence mechanism of RISNHL has not been clearly illustrated, and further studies are needed to better understand the …
The literature was examined for the possible mechanism and preventive measures of sensorineural hearing loss induced by radiotherapy. …
Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review.
Yu W, Zong S, Du P, Zhou P, Li H, Wang E, Xiao H. Yu W, et al. Front Neurosci. 2021 Nov 19;15:774585. doi: 10.3389/fnins.2021.774585. eCollection 2021. Front Neurosci. 2021. PMID: 34867173 Free PMC article. Review.
With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the pathogenesis of sensorineural hearing loss, which, in the future, will hopefully lead to the prevention, early diagnosis, and improve …
With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the …
Impact of Oral Health Educational Interventions on Oral Hygiene Status of Children with Hearing Loss: A Randomized Controlled Trial.
Moin M, Saadat S, Rafique S, Maqsood A, Lal A, Vohra F, Alam MK, Ahmed N. Moin M, et al. Biomed Res Int. 2021 Nov 17;2021:5185613. doi: 10.1155/2021/5185613. eCollection 2021. Biomed Res Int. 2021. PMID: 34950734 Free PMC article. Clinical Trial.
CONCLUSION: Maintaining oral health requires the compliance of individuals to perform different methods of preventive dentistry, such as tooth brushing and use of dental floss. ...
CONCLUSION: Maintaining oral health requires the compliance of individuals to perform different methods of preventive dentistry, such …
The Effectiveness of Hearing Protection Devices: A Systematic Review and Meta-Analysis.
Kwak C, Han W. Kwak C, et al. Int J Environ Res Public Health. 2021 Nov 7;18(21):11693. doi: 10.3390/ijerph182111693. Int J Environ Res Public Health. 2021. PMID: 34770206 Free PMC article. Review.
To prevent intensive noise exposure in advance and be safely controlled during such exposure, hearing protection devices (HPDs) have been widely used by workers. ...
To prevent intensive noise exposure in advance and be safely controlled during such exposure, hearing protection devices (HPDs) have …
Investigational Medicinal Products for the Inner Ear: Review of Clinical Trial Characteristics in ClinicalTrials.gov.
Le Prell CG. Le Prell CG. J Am Acad Audiol. 2021 Nov;32(10):670-694. doi: 10.1055/s-0041-1735522. Epub 2022 May 24. J Am Acad Audiol. 2021. PMID: 35609594 Free PMC article. Review.
PURPOSE: The purpose of this review was to describe the state of the science regarding clinical testing of investigational medicinal products for the inner ear with respect to treatment or prevention of acquired hearing loss. DATA COLLECTION AND ANALYSIS: Comprehensive sea …
PURPOSE: The purpose of this review was to describe the state of the science regarding clinical testing of investigational medicinal product …
Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations.
Bisogno A, Scarpa A, Di Girolamo S, De Luca P, Cassandro C, Viola P, Ricciardiello F, Greco A, Vincentiis M, Ralli M, Di Stadio A. Bisogno A, et al. Life (Basel). 2021 Oct 17;11(10):1102. doi: 10.3390/life11101102. Life (Basel). 2021. PMID: 34685474 Free PMC article. Review.
In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of the effects of hearing rehabilitation for early prevention of cognitive decline....
In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of …
A Review on Recent Advancement on Age-Related Hearing Loss: The Applications of Nanotechnology, Drug Pharmacology, and Biotechnology.
Chester J, Johnston E, Walker D, Jones M, Ionescu CM, Wagle SR, Kovacevic B, Brown D, Mikov M, Mooranian A, Al-Salami H. Chester J, et al. Pharmaceutics. 2021 Jul 8;13(7):1041. doi: 10.3390/pharmaceutics13071041. Pharmaceutics. 2021. PMID: 34371732 Free PMC article. Review.
It remains largely untreatable apart from hearing aids, and with no globally established prevention strategies in the clinical setting. Hence, this review aims to explore the pathophysiology of presbycusis and potential therapies, based on a recent advancement in bile acid …
It remains largely untreatable apart from hearing aids, and with no globally established prevention strategies in the clinical settin …
Prevalence of aminoglycoside-induced hearing loss in drug-resistant tuberculosis patients: A systematic review.
Dillard LK, Martinez RX, Perez LL, Fullerton AM, Chadha S, McMahon CM. Dillard LK, et al. J Infect. 2021 Jul;83(1):27-36. doi: 10.1016/j.jinf.2021.05.010. Epub 2021 May 17. J Infect. 2021. PMID: 34015383 Free article. Review.
Widespread prevention of hearing loss can be achieved by following updated WHO guidelines for DR-TB treatment. When hearing loss cannot be avoided, secondary and tertiary prevention should be prioritized....
Widespread prevention of hearing loss can be achieved by following updated WHO guidelines for DR-TB treatment. When hearing loss cann …
Autophagy: A Novel Horizon for Hair Cell Protection.
Liu C, Zheng Z, Wang P, He S, He Y. Liu C, et al. Neural Plast. 2021 Jun 29;2021:5511010. doi: 10.1155/2021/5511010. eCollection 2021. Neural Plast. 2021. PMID: 34306061 Free PMC article. Review.
Systematic Review of Interventions to Prevent Occupational Noise-Induced Hearing Loss - A Follow-up.
Samelli AG, Matas CG, Gomes RF, Morata TC. Samelli AG, et al. Codas. 2021 Jun 2;33(4):e20190189. doi: 10.1590/2317-1782/20202019189. eCollection 2021. Codas. 2021. PMID: 34105690 Free article. English, Portuguese.
PURPOSE: To conduct a systematic review of the effectiveness of interventions to prevent occupational hearing loss, following up on the findings of the most recent version of Cochrane systematic review on the same topic. ...
PURPOSE: To conduct a systematic review of the effectiveness of interventions to prevent occupational hearing loss, following up on t …
Are dental hygienists at risk for noise-induced hearing loss? A literature review.
Henneberry K, Hilland S, Haslam SK. Henneberry K, et al. Can J Dent Hyg. 2021 Jun 1;55(2):110-119. Can J Dent Hyg. 2021. PMID: 34221035 Free PMC article. Review.
Oral health professionals need to be aware of this risk and the preventive measures they can take to reduce the potential for hearing loss. Effective preventive measures may include hearing protective devices (HPDs), educational programs, insulated noise-absorbing m …
Oral health professionals need to be aware of this risk and the preventive measures they can take to reduce the potential for hearing …
Genetic Polymorphisms in Sudden Sensorineural Hearing Loss: An Update.
Corazzi V, Ciorba A, Bianchini C, Pelucchi S, Skarżyński PH, Hatzopoulos S. Corazzi V, et al. Ear Nose Throat J. 2021 Jun;100(3_suppl):337S-342S. doi: 10.1177/0145561320944657. Epub 2020 Aug 17. Ear Nose Throat J. 2021. PMID: 32804576 Free article.
CONCLUSIONS: The potential identification of a genetic profile related to SSNHL could provide a more accurate prognostic evidence of idiopathic SSNHL (ISSNHL), offering to the patients not only early-prevention strategies but eventually information on various inheritance m …
CONCLUSIONS: The potential identification of a genetic profile related to SSNHL could provide a more accurate prognostic evidence of idiopat …
Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway.
Peixoto Pinheiro B, Vona B, Löwenheim H, Rüttiger L, Knipper M, Adel Y. Peixoto Pinheiro B, et al. Pflugers Arch. 2021 May;473(5):823-840. doi: 10.1007/s00424-020-02496-w. Epub 2020 Dec 17. Pflugers Arch. 2021. PMID: 33336302 Free PMC article. Review.
Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel K(V)7.4 (KCNQ4) in outer hair cells, inspiring future therapies to maintain or prevent the decline of potassium …
Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the …
Loud Music and Leisure Noise Is a Common Cause of Chronic Hearing Loss, Tinnitus and Hyperacusis.
Pienkowski M. Pienkowski M. Int J Environ Res Public Health. 2021 Apr 16;18(8):4236. doi: 10.3390/ijerph18084236. Int J Environ Res Public Health. 2021. PMID: 33923580 Free PMC article. Review.
This review summarizes evidence that loud music and other forms of "leisure noise" are common causes of noise-induced hearing loss, tinnitus, and hyperacusis, even if audiometric thresholds initially remain within clinically normal limits. Given the huge global burden of preve
This review summarizes evidence that loud music and other forms of "leisure noise" are common causes of noise-induced hearing loss, tinnitus …
Congenital Human Cytomegalovirus Infection Inducing Sensorineural Hearing Loss.
Xia W, Yan H, Zhang Y, Wang C, Gao W, Lv C, Wang W, Liu Z. Xia W, et al. Front Microbiol. 2021 Apr 14;12:649690. doi: 10.3389/fmicb.2021.649690. eCollection 2021. Front Microbiol. 2021. PMID: 33936007 Free PMC article. Review.
Ganciclovir, mainly used for antiviral therapy and behavioral prevention, can, to some degree, prevent congenital HCMV infection. ...A comprehensive understanding of cytomegalovirus's pathogenesis is of key importance for preventing, diagnosing, and treating …
Ganciclovir, mainly used for antiviral therapy and behavioral prevention, can, to some degree, prevent congenital HCMV infecti …
Translational implications of the interactions between hormones and age-related hearing loss.
Frisina RD, Bazard P, Bauer M, Pineros J, Zhu X, Ding B. Frisina RD, et al. Hear Res. 2021 Mar 15;402:108093. doi: 10.1016/j.heares.2020.108093. Epub 2020 Oct 15. Hear Res. 2021. PMID: 33097316 Free PMC article. Review.
In closing, exciting research completed to date, summarized in the present report bodes well for emerging biomedical therapies to prevent or treat age-related hearing loss utilizing hormonal strategies....
In closing, exciting research completed to date, summarized in the present report bodes well for emerging biomedical therapies to prevent
Using the Zebrafish Lateral Line to Understand the Roles of Mitochondria in Sensorineural Hearing Loss.
Holmgren M, Sheets L. Holmgren M, et al. Front Cell Dev Biol. 2021 Feb 5;8:628712. doi: 10.3389/fcell.2020.628712. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33614633 Free PMC article. Review.
The zebrafish lateral line is a valuable model in which to study the roles of mitochondria in hair-cell pathologies and to develop therapeutic strategies to prevent sensorineural hearing loss in humans....
The zebrafish lateral line is a valuable model in which to study the roles of mitochondria in hair-cell pathologies and to develop therapeut …
Preventive Care Utilization among Adults with Hearing Loss in the United States.
Fioravante N, Deal JA, Willink A, Myers C, Assi L. Fioravante N, et al. Semin Hear. 2021 Feb;42(1):37-46. doi: 10.1055/s-0041-1725999. Epub 2021 Apr 15. Semin Hear. 2021. PMID: 33883790 Free PMC article. Review.
Hearing loss (HL) can negatively impact patient-provider communication and limit access to health promotion information, which may lead to decreased preventive care utilization. Using data from the 2015 and 2018 National Health Interview Survey, we examined the association …
Hearing loss (HL) can negatively impact patient-provider communication and limit access to health promotion information, which may lead to d …
OTOF-Related Deafness.
Azaiez H, Thorpe RK, Smith RJH. Azaiez H, et al. 2008 Feb 29 [updated 2021 Jan 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2008 Feb 29 [updated 2021 Jan 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301429 Free Books & Documents. Review.
Educational programs designed for individuals with hearing impairment should start as early as possible. Prevention of primary manifestations: For individuals with TS-ANSD, prevent fevers and other activities/ambient conditions that would cause body temperature to r …
Educational programs designed for individuals with hearing impairment should start as early as possible. Prevention of primary manife …
Protective effects of vitamins/antioxidants on occupational noise-induced hearing loss: A systematic review.
Abbasi M, Pourrajab B, Tokhi MO. Abbasi M, et al. J Occup Health. 2021 Jan;63(1):e12217. doi: 10.1002/1348-9585.12217. J Occup Health. 2021. PMID: 33788342 Free PMC article.
OBJECTIVES: Occupational noise-induced hearing loss (NIHL) due to industrial, military, and other job -related noise exposure can cause harmful health issues to occupied workers, but may also be potentially preventable. Vitamins/antioxidant have been studied as therapeutic …
OBJECTIVES: Occupational noise-induced hearing loss (NIHL) due to industrial, military, and other job -related noise exposure can cause harm …
Pharmacological Prevention of Noise-induced Hearing Loss: A Systematic Review.
Gupta A, Koochakzadeh S, Nguyen SA, Brennan EA, Meyer TA, Lambert PR. Gupta A, et al. Otol Neurotol. 2021 Jan;42(1):2-9. doi: 10.1097/MAO.0000000000002858. Otol Neurotol. 2021. PMID: 33229875 Free PMC article.
OBJECTIVE: This study aims to explore and determine the effectiveness of current pharmacologic agents for the prevention of noise-induced hearing loss (NIHL) via a systematic review. ...Initial data from this study alongside future clinical trials might potentially contrib …
OBJECTIVE: This study aims to explore and determine the effectiveness of current pharmacologic agents for the prevention of noise-ind …
Role of nutrition in the development and prevention of age-related hearing loss: A scoping review.
Rodrigo L, Campos-Asensio C, Rodríguez MÁ, Crespo I, Olmedillas H. Rodrigo L, et al. J Formos Med Assoc. 2021 Jan;120(1 Pt 1):107-120. doi: 10.1016/j.jfma.2020.05.011. Epub 2020 May 28. J Formos Med Assoc. 2021. PMID: 32473863 Free article. Review.
Diets rich in saturated fats and cholesterol have deleterious effects on hearing that could be prevented by lower consumption. Conversely, greater consumption of fruit and vegetables, and of polyunsaturated fatty acids (omega-3) and anti-oxidants in the form of vitamins A, …
Diets rich in saturated fats and cholesterol have deleterious effects on hearing that could be prevented by lower consumption. Conver …
Advances in genome editing for genetic hearing loss.
Ding N, Lee S, Lieber-Kotz M, Yang J, Gao X. Ding N, et al. Adv Drug Deliv Rev. 2021 Jan;168:118-133. doi: 10.1016/j.addr.2020.05.001. Epub 2020 May 7. Adv Drug Deliv Rev. 2021. PMID: 32387678 Free PMC article. Review.
It is estimated that genetic factors contribute to the causation of approximately 50% of congenital hearing loss. Yet, curative approaches to reversing or preventing genetic hearing impairment are still limited. The clustered regularly interspaced short palindromic repeats …
It is estimated that genetic factors contribute to the causation of approximately 50% of congenital hearing loss. Yet, curative approaches t …
Approach to hearing loss.
Newsted D, Rosen E, Cooke B, Beyea MM, Simpson MTW, Beyea JA. Newsted D, et al. Can Fam Physician. 2020 Nov;66(11):803-809. Can Fam Physician. 2020. PMID: 33208419 Free PMC article. Review.
Frequently, referral or urgent workup, including imaging, is necessary to confirm a patient's diagnosis and initiate management in order to prevent further complications....
Frequently, referral or urgent workup, including imaging, is necessary to confirm a patient's diagnosis and initiate management in order to …
An overview of occupational noise-induced hearing loss among workers: epidemiology, pathogenesis, and preventive measures.
Chen KH, Su SB, Chen KT. Chen KH, et al. Environ Health Prev Med. 2020 Oct 31;25(1):65. doi: 10.1186/s12199-020-00906-0. Environ Health Prev Med. 2020. PMID: 33129267 Free PMC article. Review.
The goal of this study was to review the epidemiology, pathogenesis, and preventive measures of ONIHL among workers and provide evidence for the implementation of control measures. ...Noise exposure may contribute to temporary or permanent threshold shifts; however, even t …
The goal of this study was to review the epidemiology, pathogenesis, and preventive measures of ONIHL among workers and provide evide …
The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer.
Zaharija B, Samardžija B, Bradshaw NJ. Zaharija B, et al. Molecules. 2020 Oct 27;25(21):4967. doi: 10.3390/molecules25214967. Molecules. 2020. PMID: 33121024 Free PMC article. Review.
TRIOBP-1 (also known as TARA or TAP68) is a mainly structured protein that is ubiquitously expressed and binds to F-actin, preventing its depolymerization. It has been shown to be important for many processes including in the cell cycle, adhesion junctions, and neuronal di …
TRIOBP-1 (also known as TARA or TAP68) is a mainly structured protein that is ubiquitously expressed and binds to F-actin, preventing
New trends in the prevention of occupational noise-induced hearing loss.
Sliwinska-Kowalska M. Sliwinska-Kowalska M. Int J Occup Med Environ Health. 2020 Oct 20;33(6):841-848. doi: 10.13075/ijomeh.1896.01600. Epub 2020 Sep 29. Int J Occup Med Environ Health. 2020. PMID: 32994587 Free article. Review.
This paper reviews recent research on the effects of noise on hearing in pursuit of more effective methods for the prevention of occupational NIHL. The paper discusses the translational significance of noise-induced cochlear neuropathy, as recently shown in animals, and th …
This paper reviews recent research on the effects of noise on hearing in pursuit of more effective methods for the prevention of occu …
Noise Induced Hearing Loss and Tinnitus-New Research Developments and Remaining Gaps in Disease Assessment, Treatment, and Prevention.
Wang TC, Chang TY, Tyler R, Lin YJ, Liang WM, Shau YW, Lin WY, Chen YW, Lin CD, Tsai MH. Wang TC, et al. Brain Sci. 2020 Oct 13;10(10):732. doi: 10.3390/brainsci10100732. Brain Sci. 2020. PMID: 33066210 Free PMC article. Review.
Increasing knowledge of neural plasticity and adaptive changes in the central auditory system suggest that NIHL is preventable and transient abnormalities may be reversable, although ongoing research in assessment and early detection of hearing difficulties is still urgent …
Increasing knowledge of neural plasticity and adaptive changes in the central auditory system suggest that NIHL is preventable and tr …
Phase 1 study to evaluate safety, tolerability and pharmacokinetics of a novel intra-tympanic administered thiosulfate to prevent cisplatin-induced hearing loss in cancer patients.
Viglietta V, Shi F, Hu QY, Ren Y, Keilty J, Wolff H, McCarthy R, Kropp J, Weber P, Soglia J. Viglietta V, et al. Invest New Drugs. 2020 Oct;38(5):1463-1471. doi: 10.1007/s10637-020-00918-1. Epub 2020 Mar 10. Invest New Drugs. 2020. PMID: 32157599 Free PMC article. Clinical Trial.
Ototoxicity and subsequent permanent hearing loss remain a serious dose-limiting side effect associated with cisplatin treatment. To date, no therapies have been approved to prevent or treat cisplatin-induced hearing loss (CIHL). Sodium thiosulfate effectively inactivates …
Ototoxicity and subsequent permanent hearing loss remain a serious dose-limiting side effect associated with cisplatin treatment. To date, n …
Which interventions increase hearing protection behaviors during noisy recreational activities? A systematic review.
Loughran MT, Lyons S, Plack CJ, Armitage CJ. Loughran MT, et al. BMC Public Health. 2020 Sep 13;20(1):1376. doi: 10.1186/s12889-020-09414-w. BMC Public Health. 2020. PMID: 32919462 Free PMC article.
CONCLUSIONS: Hearing loss and tinnitus due to recreational noise exposure are major public health concerns yet very few studies have examined preventive interventions. The present systematic review sets the agenda for the future development and testing of evidence-based in …
CONCLUSIONS: Hearing loss and tinnitus due to recreational noise exposure are major public health concerns yet very few studies have examine …
Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness.
Leake PA, Akil O, Lang H. Leake PA, et al. Hear Res. 2020 Sep 1;394:107955. doi: 10.1016/j.heares.2020.107955. Epub 2020 Apr 5. Hear Res. 2020. PMID: 32331858 Free PMC article. Review.
This review summarizes the evidence for the efficacy of exogenous NTs in preventing SGN degeneration after hearing loss and reviews the animal research to date suggesting that NT gene therapy can elicit long-term NT expression in the cochlea, resulting in significantly imp …
This review summarizes the evidence for the efficacy of exogenous NTs in preventing SGN degeneration after hearing loss and reviews t …
Diagnostic and therapeutic applications of genomic medicine in progressive, late-onset, nonsyndromic sensorineural hearing loss.
Jimenez JE, Nourbakhsh A, Colbert B, Mittal R, Yan D, Green CL, Nisenbaum E, Liu G, Bencie N, Rudman J, Blanton SH, Zhong Liu X. Jimenez JE, et al. Gene. 2020 Jul 15;747:144677. doi: 10.1016/j.gene.2020.144677. Epub 2020 Apr 15. Gene. 2020. PMID: 32304785 Free PMC article. Review.
Many gene therapy modalities that have proven efficacious in animal trials have potential to delay or prevent PNSHL in humans. The development of new treatment modalities for PNSHL will lead to improved quality of life of many affected individuals and their families....
Many gene therapy modalities that have proven efficacious in animal trials have potential to delay or prevent PNSHL in humans. The de …
Cochrane method for systematic review and meta-analysis of interventions to prevent occupational noise-induced hearing loss - abridged.
Tikka C, Verbeek J, Kateman E, Morata TC, Dreschler W, Ferrite S. Tikka C, et al. Codas. 2020 Apr 3;32(2):e20190127. doi: 10.1590/2317-1782/20192019127. eCollection 2020. Codas. 2020. PMID: 32267337 Free article.
Seventeen studies (84028 participants) evaluated hearing loss prevention programs. Better use of HPDs might reduce hearing loss but other components not (very low-quality evidence). CONCLUSION: Hearing loss prevention and interventions modestly reduce noise exposure …
Seventeen studies (84028 participants) evaluated hearing loss prevention programs. Better use of HPDs might reduce hearing loss but o …
Does Treating Hearing Loss in Older Adults Improve Cognitive Outcomes? A Review.
Amieva H, Ouvrard C. Amieva H, et al. J Clin Med. 2020 Mar 16;9(3):805. doi: 10.3390/jcm9030805. J Clin Med. 2020. PMID: 32188074 Free PMC article. Review.
Nevertheless, because hearing loss is suspected to account for 9% of dementia cases, and also because hearing loss is one of the few potentially modifiable factors from a dementia prevention perspective, the need to stimulate research to have clearer knowledge of the benef …
Nevertheless, because hearing loss is suspected to account for 9% of dementia cases, and also because hearing loss is one of the few potenti …
Classification of audiograms in the prevention of noise-induced hearing loss: A clinical perspective.
Musiba Z. Musiba Z. S Afr J Commun Disord. 2020 Mar 3;67(2):e1-e5. doi: 10.4102/sajcd.v67i2.691. S Afr J Commun Disord. 2020. PMID: 32129662 Free PMC article. Review.
Engineering controls are superior to hearing protection devices (HPDs) in prevention of occupational noise induced hearing loss (ONIHL), although the latter are more commonly used. ...
Engineering controls are superior to hearing protection devices (HPDs) in prevention of occupational noise induced hearing loss (ONIH …
Risk versus benefit: Should not audiologists assess this in the context of occupational noise-induced hearing loss in the mining industry?
Khoza-Shangase K, Moroe NF. Khoza-Shangase K, et al. S Afr J Commun Disord. 2020 Mar 3;67(2):e1-e9. doi: 10.4102/sajcd.v67i2.671. S Afr J Commun Disord. 2020. PMID: 32129658 Free PMC article. Review.
BACKGROUND: Hearing conservation programmes (HCPs) are an important aspect of occupational health efforts to prevent occupational noise-induced hearing loss (ONIHL). In low- and middle income (LAMI) countries, where the incidence of ONIHL is significant, it is important to …
BACKGROUND: Hearing conservation programmes (HCPs) are an important aspect of occupational health efforts to prevent occupational noi …
Different infusion durations for preventing platinum-induced hearing loss in children with cancer.
van As JW, van den Berg H, van Dalen EC. van As JW, et al. Cochrane Database Syst Rev. 2020 Jan 21;1(1):CD010885. doi: 10.1002/14651858.CD010885.pub5. Cochrane Database Syst Rev. 2020. PMID: 31961948 Free PMC article.
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different platinum infusion durations have been studied. ...OBJECTIVES: To assess the effects of different durations of plat …
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent th …
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