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Alcohol as a risk factor for hearing loss: A systematic review and meta-analysis.
Qian P, Zhao Z, Liu S, Xin J, Liu Y, Hao Y, Wang Y, Yang L. Qian P, et al. PLoS One. 2023 Jan 20;18(1):e0280641. doi: 10.1371/journal.pone.0280641. eCollection 2023. PLoS One. 2023. PMID: 36662896 Free PMC article.
Drinkers were at a higher risk than non-drinkers. Drinking limitations may be useful for preventing hearing loss....
Drinkers were at a higher risk than non-drinkers. Drinking limitations may be useful for preventing hearing loss....
The ubiquitin-proteasome system in normal hearing and deafness.
Pouyo R, Chung K, Delacroix L, Malgrange B. Pouyo R, et al. Hear Res. 2022 Dec;426:108366. doi: 10.1016/j.heares.2021.108366. Epub 2021 Sep 29. Hear Res. 2022. PMID: 34645583 Free article. Review.
The most common outcome of protein ubiquitination is degradation by the ubiquitin-proteasome system (UPS), preventing the accumulation of misfolded, damaged, and excess proteins. ...In this review, we provide insight into the well-oiled machinery of UPS with a focus on its …
The most common outcome of protein ubiquitination is degradation by the ubiquitin-proteasome system (UPS), preventing the accumulatio …
Linking Cerebrovascular Dysfunction to Age-Related Hearing Loss and Alzheimer's Disease-Are Systemic Approaches for Diagnosis and Therapy Required?
Förster CY, Shityakov S, Scheper V, Lenarz T. Förster CY, et al. Biomolecules. 2022 Nov 19;12(11):1717. doi: 10.3390/biom12111717. Biomolecules. 2022. PMID: 36421731 Free PMC article. Review.
Finally, there are options for the treatment of ARHL by targeted neurotrophic factor supplementation to the cochlea to improve cognitive outcomes; they can also prevent AD development and AD-related comorbidity in the future....
Finally, there are options for the treatment of ARHL by targeted neurotrophic factor supplementation to the cochlea to improve cognitive out …
Clinical Features and Prognosis of Facial Palsy and Hearing Loss in Patients With Ramsay Hunt Syndrome.
Malhotra R, Mudey A, Agrawal I. Malhotra R, et al. Cureus. 2022 Oct 31;14(10):e30897. doi: 10.7759/cureus.30897. eCollection 2022 Oct. Cureus. 2022. PMID: 36465761 Free PMC article. Review.
The course and outcome of facial nerve palsy is determined by the early clinical picture, while the otological symptoms rely on the extent of nerve involvement. Early diagnosis and treatment go a long way in preventing these complications and increasing the chances of comp …
The course and outcome of facial nerve palsy is determined by the early clinical picture, while the otological symptoms rely on the extent o …
Impacts of impaired mitochondrial dynamics in hearing loss: Potential therapeutic targets.
Zou T, Ye B, Chen K, Zhang A, Guo D, Pan Y, Ding R, Hu H, Sun X, Xiang M. Zou T, et al. Front Neurosci. 2022 Oct 5;16:998507. doi: 10.3389/fnins.2022.998507. eCollection 2022. Front Neurosci. 2022. PMID: 36278017 Free PMC article. Review.
The impacts of impaired mitochondrial dynamics on hearing loss are discussed, and the potential of mitochondrial dynamics for the prevention and treatment of hearing loss is considered....
The impacts of impaired mitochondrial dynamics on hearing loss are discussed, and the potential of mitochondrial dynamics for the prevent …
Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer's Disease: A Narrative Review.
Tarawneh HY, Jayakody DMP, Sohrabi HR, Martins RN, Mulders WHAM. Tarawneh HY, et al. J Alzheimers Dis Rep. 2022 Sep 12;6(1):539-556. doi: 10.3233/ADR-220035. eCollection 2022. J Alzheimers Dis Rep. 2022. PMID: 36275417 Free PMC article. Review.
Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, prevention, and/or treatment of AD. This paper also provides insight into the current evidence for the use of hearing treatments as …
Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, …
The Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) study: International consensus on outcome measures for trials of interventions for adults with single-sided deafness.
Katiri R, Hall DA, Hoare DJ, Fackrell K, Horobin A, Hogan N, Buggy N, Van de Heyning PH, Firszt JB, Bruce IA, Kitterick PT; Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) initiative. Katiri R, et al. Trials. 2022 Sep 8;23(1):764. doi: 10.1186/s13063-022-06702-1. Trials. 2022. PMID: 36076299 Free PMC article.
Benefits and harms (outcome domains) of these interventions are until now reported inconsistently in clinical trials. Inconsistency in reporting outcome measures prevents meaningful comparisons or syntheses of trial results. The Core Rehabilitation Outcome Set for Single-S …
Benefits and harms (outcome domains) of these interventions are until now reported inconsistently in clinical trials. Inconsistency in repor …
Effect of N-acetyl-cysteine treatment on sensorineural hearing loss: a meta-analysis.
Bai X, Wang M, Niu X, Yu H, Yue JX, Sun Y. Bai X, et al. World J Otorhinolaryngol Head Neck Surg. 2022 May 12;8(3):205-212. doi: 10.1016/j.wjorl.2021.01.005. eCollection 2022 Sep. World J Otorhinolaryngol Head Neck Surg. 2022. PMID: 36159904 Free PMC article. Review.
However, NAC treatment was linked with improved patient outcomes of hearing tests in cases of sudden hearing loss, but did not prevent hearing loss induced by noise or ototoxicity. However, there is a need for better-designed studies with larger samples to further prove th …
However, NAC treatment was linked with improved patient outcomes of hearing tests in cases of sudden hearing loss, but did not prevent …
Global burden of ototoxic hearing loss associated with platinum-based cancer treatment: A systematic review and meta-analysis.
Dillard LK, Lopez-Perez L, Martinez RX, Fullerton AM, Chadha S, McMahon CM. Dillard LK, et al. Cancer Epidemiol. 2022 Aug;79:102203. doi: 10.1016/j.canep.2022.102203. Epub 2022 Jun 17. Cancer Epidemiol. 2022. PMID: 35724557 Free PMC article. Review.
This can be partially achieved by implementing existing strategies focused on primary, secondary, and tertiary hearing loss prevention. Primary ototoxicity prevention via otoprotectants should be a research and policy priority....
This can be partially achieved by implementing existing strategies focused on primary, secondary, and tertiary hearing loss prevention …
Preventive Effects of Ginkgo-Extract EGb 761® on Noise Trauma-Induced Cochlear Synaptopathy.
Tziridis K, Schulze H. Tziridis K, et al. Nutrients. 2022 Jul 22;14(15):3015. doi: 10.3390/nu14153015. Nutrients. 2022. PMID: 35893868 Free PMC article. Clinical Trial.
One of these causes may be the mentioned loss of ribbon synapses at the IHC of the cochlea. In this study, we investigated the possible preventive and curative effects of the Ginkgo biloba extract EGb 761() on noise-induced synaptopathy, HL, and tinnitus development in Mon …
One of these causes may be the mentioned loss of ribbon synapses at the IHC of the cochlea. In this study, we investigated the possible p …
The Role of Genetic Variants in the Susceptibility of Noise-Induced Hearing Loss.
Chen XM, Xue XM, Yu N, Guo WW, Yuan SL, Jiang QQ, Yang SM. Chen XM, et al. Front Cell Neurosci. 2022 Jul 12;16:946206. doi: 10.3389/fncel.2022.946206. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35903368 Free PMC article. Review.
In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, intending to give insights into the further exploration of NIHL prevention and individual treatment....
In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, …
Advancements in prevention and intervention of sensorineural hearing loss.
Ren H, Hu B, Jiang G. Ren H, et al. Ther Adv Chronic Dis. 2022 Jun 27;13:20406223221104987. doi: 10.1177/20406223221104987. eCollection 2022. Ther Adv Chronic Dis. 2022. PMID: 35782345 Free PMC article. Review.
In this article, we review the recent advances about SHNL and discuss the complexities and challenges of prevention and intervention of SNHL....
In this article, we review the recent advances about SHNL and discuss the complexities and challenges of prevention and intervention …
Prevention of Noise-Induced Hearing Loss Using Investigational Medicines for the Inner Ear: Previous Trial Outcomes Should Inform Future Trial Design.
Le Prell CG. Le Prell CG. Antioxid Redox Signal. 2022 Jun;36(16-18):1171-1202. doi: 10.1089/ars.2021.0166. Epub 2021 Oct 4. Antioxid Redox Signal. 2022. PMID: 34346254 Free PMC article. Review.
Recent Advances: Advances in the mechanistic understanding of NIHL have prompted a growing number of proposed, in-progress, and completed clinical trials for possible protections against NIHL via antioxidants and other drug agents. Thirty-one clinical trials evaluating prevent …
Recent Advances: Advances in the mechanistic understanding of NIHL have prompted a growing number of proposed, in-progress, and completed cl …
Unexpected Consequences of Noise-Induced Hearing Loss: Impaired Hippocampal Neurogenesis, Memory, and Stress.
Manohar S, Chen GD, Ding D, Liu L, Wang J, Chen YC, Chen L, Salvi R. Manohar S, et al. Front Integr Neurosci. 2022 May 10;16:871223. doi: 10.3389/fnint.2022.871223. eCollection 2022. Front Integr Neurosci. 2022. PMID: 35619926 Free PMC article. Review.
These experimental results may provide new insights on why hearing loss is a risk factor for cognitive decline and suggest methods for preventing this decline....
These experimental results may provide new insights on why hearing loss is a risk factor for cognitive decline and suggest methods for pr …
Immune-Mediated Association Between Celiac Disease and Sensorineural Hearing Loss: A Systematic Narrative Review.
De Luca P, Scarpa A, Ralli M, Tassone D, Cassandro C, Simone M, de Campora L, Camaioni A. De Luca P, et al. Turk J Gastroenterol. 2022 Apr;33(4):273-279. doi: 10.5152/tjg.2022.21554. Turk J Gastroenterol. 2022. PMID: 35550535 Free PMC article.
Despite existing literature not clarifying the link between celiac disease and sensorineural hearing loss, some authors proposed hearing screening in younger patients with celiac disease, to prevent the behavioral, cognitive, and sensorimotor impairment of hearing loss. .. …
Despite existing literature not clarifying the link between celiac disease and sensorineural hearing loss, some authors proposed hearing scr …
Hearing Loss and Cognition: What We Know and Where We Need to Go.
Powell DS, Oh ES, Reed NS, Lin FR, Deal JA. Powell DS, et al. Front Aging Neurosci. 2022 Feb 28;13:769405. doi: 10.3389/fnagi.2021.769405. eCollection 2021. Front Aging Neurosci. 2022. PMID: 35295208 Free PMC article. Review.
These selected research priorities include examination of the causal mechanism, measurement of co-existing hearing loss and cognitive impairment and determination of any bias in testing, potential for managing hearing loss for prevention of dementia and cognitive decline, …
These selected research priorities include examination of the causal mechanism, measurement of co-existing hearing loss and cognitive impair …
Effect of N-acetyl-cysteine in prevention of noise-induced hearing loss: a systematic review and meta-analysis of randomized controlled trials.
Chang PH, Liu CW, Hung SH, Kang YN. Chang PH, et al. Arch Med Sci. 2021 Mar 21;18(6):1535-1541. doi: 10.5114/aoms/109126. eCollection 2022. Arch Med Sci. 2021. PMID: 36457967 Free PMC article. Review.
Although multiple factors lead to noise-induced hearing loss, prevention and protection strategies remain limited. Studies in the past decade have employed antioxidants, especially N-acetyl-cysteine, to prevent noise-induced hearing loss. Therefore, this systematic …
Although multiple factors lead to noise-induced hearing loss, prevention and protection strategies remain limited. Studies in the pas …
Mechanism and Protection of Radiotherapy Induced Sensorineural Hearing Loss for Head and Neck Cancer.
Shi W, Hou X, Bao X, Hou W, Jiang X, Ma L, Jiang X, Dong L. Shi W, et al. Biomed Res Int. 2021 Dec 21;2021:3548706. doi: 10.1155/2021/3548706. eCollection 2021. Biomed Res Int. 2021. PMID: 34970625 Free PMC article. Review.
The literature was examined for the possible mechanism and preventive measures of sensorineural hearing loss induced by radiotherapy. ...At present, the occurrence mechanism of RISNHL has not been clearly illustrated, and further studies are needed to better understand the …
The literature was examined for the possible mechanism and preventive measures of sensorineural hearing loss induced by radiotherapy. …
Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review.
Yu W, Zong S, Du P, Zhou P, Li H, Wang E, Xiao H. Yu W, et al. Front Neurosci. 2021 Nov 19;15:774585. doi: 10.3389/fnins.2021.774585. eCollection 2021. Front Neurosci. 2021. PMID: 34867173 Free PMC article. Review.
With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the pathogenesis of sensorineural hearing loss, which, in the future, will hopefully lead to the prevention, early diagnosis, and improve …
With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the …
Impact of Oral Health Educational Interventions on Oral Hygiene Status of Children with Hearing Loss: A Randomized Controlled Trial.
Moin M, Saadat S, Rafique S, Maqsood A, Lal A, Vohra F, Alam MK, Ahmed N. Moin M, et al. Biomed Res Int. 2021 Nov 17;2021:5185613. doi: 10.1155/2021/5185613. eCollection 2021. Biomed Res Int. 2021. PMID: 34950734 Free PMC article. Clinical Trial.
CONCLUSION: Maintaining oral health requires the compliance of individuals to perform different methods of preventive dentistry, such as tooth brushing and use of dental floss. ...
CONCLUSION: Maintaining oral health requires the compliance of individuals to perform different methods of preventive dentistry, such …
The Effectiveness of Hearing Protection Devices: A Systematic Review and Meta-Analysis.
Kwak C, Han W. Kwak C, et al. Int J Environ Res Public Health. 2021 Nov 7;18(21):11693. doi: 10.3390/ijerph182111693. Int J Environ Res Public Health. 2021. PMID: 34770206 Free PMC article. Review.
To prevent intensive noise exposure in advance and be safely controlled during such exposure, hearing protection devices (HPDs) have been widely used by workers. ...
To prevent intensive noise exposure in advance and be safely controlled during such exposure, hearing protection devices (HPDs) have …
Investigational Medicinal Products for the Inner Ear: Review of Clinical Trial Characteristics in ClinicalTrials.gov.
Le Prell CG. Le Prell CG. J Am Acad Audiol. 2021 Nov;32(10):670-694. doi: 10.1055/s-0041-1735522. Epub 2022 May 24. J Am Acad Audiol. 2021. PMID: 35609594 Free PMC article. Review.
PURPOSE: The purpose of this review was to describe the state of the science regarding clinical testing of investigational medicinal products for the inner ear with respect to treatment or prevention of acquired hearing loss. DATA COLLECTION AND ANALYSIS: Comprehensive sea …
PURPOSE: The purpose of this review was to describe the state of the science regarding clinical testing of investigational medicinal product …
Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations.
Bisogno A, Scarpa A, Di Girolamo S, De Luca P, Cassandro C, Viola P, Ricciardiello F, Greco A, Vincentiis M, Ralli M, Di Stadio A. Bisogno A, et al. Life (Basel). 2021 Oct 17;11(10):1102. doi: 10.3390/life11101102. Life (Basel). 2021. PMID: 34685474 Free PMC article. Review.
In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of the effects of hearing rehabilitation for early prevention of cognitive decline....
In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of …
A Review on Recent Advancement on Age-Related Hearing Loss: The Applications of Nanotechnology, Drug Pharmacology, and Biotechnology.
Chester J, Johnston E, Walker D, Jones M, Ionescu CM, Wagle SR, Kovacevic B, Brown D, Mikov M, Mooranian A, Al-Salami H. Chester J, et al. Pharmaceutics. 2021 Jul 8;13(7):1041. doi: 10.3390/pharmaceutics13071041. Pharmaceutics. 2021. PMID: 34371732 Free PMC article. Review.
It remains largely untreatable apart from hearing aids, and with no globally established prevention strategies in the clinical setting. Hence, this review aims to explore the pathophysiology of presbycusis and potential therapies, based on a recent advancement in bile acid …
It remains largely untreatable apart from hearing aids, and with no globally established prevention strategies in the clinical settin …
Prevalence of aminoglycoside-induced hearing loss in drug-resistant tuberculosis patients: A systematic review.
Dillard LK, Martinez RX, Perez LL, Fullerton AM, Chadha S, McMahon CM. Dillard LK, et al. J Infect. 2021 Jul;83(1):27-36. doi: 10.1016/j.jinf.2021.05.010. Epub 2021 May 17. J Infect. 2021. PMID: 34015383 Free article. Review.
Widespread prevention of hearing loss can be achieved by following updated WHO guidelines for DR-TB treatment. When hearing loss cannot be avoided, secondary and tertiary prevention should be prioritized....
Widespread prevention of hearing loss can be achieved by following updated WHO guidelines for DR-TB treatment. When hearing loss cann …
Autophagy: A Novel Horizon for Hair Cell Protection.
Liu C, Zheng Z, Wang P, He S, He Y. Liu C, et al. Neural Plast. 2021 Jun 29;2021:5511010. doi: 10.1155/2021/5511010. eCollection 2021. Neural Plast. 2021. PMID: 34306061 Free PMC article. Review.
Systematic Review of Interventions to Prevent Occupational Noise-Induced Hearing Loss - A Follow-up.
Samelli AG, Matas CG, Gomes RF, Morata TC. Samelli AG, et al. Codas. 2021 Jun 2;33(4):e20190189. doi: 10.1590/2317-1782/20202019189. eCollection 2021. Codas. 2021. PMID: 34105690 Free article. English, Portuguese.
PURPOSE: To conduct a systematic review of the effectiveness of interventions to prevent occupational hearing loss, following up on the findings of the most recent version of Cochrane systematic review on the same topic. ...
PURPOSE: To conduct a systematic review of the effectiveness of interventions to prevent occupational hearing loss, following up on t …
Are dental hygienists at risk for noise-induced hearing loss? A literature review.
Henneberry K, Hilland S, Haslam SK. Henneberry K, et al. Can J Dent Hyg. 2021 Jun 1;55(2):110-119. Can J Dent Hyg. 2021. PMID: 34221035 Free PMC article. Review.
Oral health professionals need to be aware of this risk and the preventive measures they can take to reduce the potential for hearing loss. Effective preventive measures may include hearing protective devices (HPDs), educational programs, insulated noise-absorbing m …
Oral health professionals need to be aware of this risk and the preventive measures they can take to reduce the potential for hearing …
Genetic Polymorphisms in Sudden Sensorineural Hearing Loss: An Update.
Corazzi V, Ciorba A, Bianchini C, Pelucchi S, Skarżyński PH, Hatzopoulos S. Corazzi V, et al. Ear Nose Throat J. 2021 Jun;100(3_suppl):337S-342S. doi: 10.1177/0145561320944657. Epub 2020 Aug 17. Ear Nose Throat J. 2021. PMID: 32804576 Free article.
CONCLUSIONS: The potential identification of a genetic profile related to SSNHL could provide a more accurate prognostic evidence of idiopathic SSNHL (ISSNHL), offering to the patients not only early-prevention strategies but eventually information on various inheritance m …
CONCLUSIONS: The potential identification of a genetic profile related to SSNHL could provide a more accurate prognostic evidence of idiopat …
Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway.
Peixoto Pinheiro B, Vona B, Löwenheim H, Rüttiger L, Knipper M, Adel Y. Peixoto Pinheiro B, et al. Pflugers Arch. 2021 May;473(5):823-840. doi: 10.1007/s00424-020-02496-w. Epub 2020 Dec 17. Pflugers Arch. 2021. PMID: 33336302 Free PMC article. Review.
Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel K(V)7.4 (KCNQ4) in outer hair cells, inspiring future therapies to maintain or prevent the decline of potassium …
Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the …
Loud Music and Leisure Noise Is a Common Cause of Chronic Hearing Loss, Tinnitus and Hyperacusis.
Pienkowski M. Pienkowski M. Int J Environ Res Public Health. 2021 Apr 16;18(8):4236. doi: 10.3390/ijerph18084236. Int J Environ Res Public Health. 2021. PMID: 33923580 Free PMC article. Review.
This review summarizes evidence that loud music and other forms of "leisure noise" are common causes of noise-induced hearing loss, tinnitus, and hyperacusis, even if audiometric thresholds initially remain within clinically normal limits. Given the huge global burden of preve …
This review summarizes evidence that loud music and other forms of "leisure noise" are common causes of noise-induced hearing loss, tinnitus …
Congenital Human Cytomegalovirus Infection Inducing Sensorineural Hearing Loss.
Xia W, Yan H, Zhang Y, Wang C, Gao W, Lv C, Wang W, Liu Z. Xia W, et al. Front Microbiol. 2021 Apr 14;12:649690. doi: 10.3389/fmicb.2021.649690. eCollection 2021. Front Microbiol. 2021. PMID: 33936007 Free PMC article. Review.
Ganciclovir, mainly used for antiviral therapy and behavioral prevention, can, to some degree, prevent congenital HCMV infection. ...A comprehensive understanding of cytomegalovirus's pathogenesis is of key importance for preventing, diagnosing, and treating …
Ganciclovir, mainly used for antiviral therapy and behavioral prevention, can, to some degree, prevent congenital HCMV infecti …
Translational implications of the interactions between hormones and age-related hearing loss.
Frisina RD, Bazard P, Bauer M, Pineros J, Zhu X, Ding B. Frisina RD, et al. Hear Res. 2021 Mar 15;402:108093. doi: 10.1016/j.heares.2020.108093. Epub 2020 Oct 15. Hear Res. 2021. PMID: 33097316 Free PMC article. Review.
In closing, exciting research completed to date, summarized in the present report bodes well for emerging biomedical therapies to prevent or treat age-related hearing loss utilizing hormonal strategies....
In closing, exciting research completed to date, summarized in the present report bodes well for emerging biomedical therapies to prevent …
Screening for Hearing Loss in Older Adults: An Evidence Review for the U.S. Preventive Services Task Force [Internet].
Feltner C, Wallace IF, Kistler CE, Coker-Schwimmer M, Jonas DE, Middleton JC. Feltner C, et al. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Mar. Report No.: 20-05269-EF-1. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Mar. Report No.: 20-05269-EF-1. PMID: 33818999 Free Books & Documents. Review.
Using the Zebrafish Lateral Line to Understand the Roles of Mitochondria in Sensorineural Hearing Loss.
Holmgren M, Sheets L. Holmgren M, et al. Front Cell Dev Biol. 2021 Feb 5;8:628712. doi: 10.3389/fcell.2020.628712. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33614633 Free PMC article. Review.
The zebrafish lateral line is a valuable model in which to study the roles of mitochondria in hair-cell pathologies and to develop therapeutic strategies to prevent sensorineural hearing loss in humans....
The zebrafish lateral line is a valuable model in which to study the roles of mitochondria in hair-cell pathologies and to develop therapeut …
Preventive Care Utilization among Adults with Hearing Loss in the United States.
Fioravante N, Deal JA, Willink A, Myers C, Assi L. Fioravante N, et al. Semin Hear. 2021 Feb;42(1):37-46. doi: 10.1055/s-0041-1725999. Epub 2021 Apr 15. Semin Hear. 2021. PMID: 33883790 Free PMC article. Review.
Hearing loss (HL) can negatively impact patient-provider communication and limit access to health promotion information, which may lead to decreased preventive care utilization. Using data from the 2015 and 2018 National Health Interview Survey, we examined the association …
Hearing loss (HL) can negatively impact patient-provider communication and limit access to health promotion information, which may lead to d …
OTOF-Related Deafness.
Azaiez H, Thorpe RK, Smith RJH. Azaiez H, et al. 2008 Feb 29 [updated 2021 Jan 21]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. 2008 Feb 29 [updated 2021 Jan 21]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. PMID: 20301429 Free Books & Documents. Review.
Educational programs designed for individuals with hearing impairment should start as early as possible. Prevention of primary manifestations: For individuals with TS-ANSD, prevent fevers and other activities/ambient conditions that would cause body temperature to r …
Educational programs designed for individuals with hearing impairment should start as early as possible. Prevention of primary manife …
Protective effects of vitamins/antioxidants on occupational noise-induced hearing loss: A systematic review.
Abbasi M, Pourrajab B, Tokhi MO. Abbasi M, et al. J Occup Health. 2021 Jan;63(1):e12217. doi: 10.1002/1348-9585.12217. J Occup Health. 2021. PMID: 33788342 Free PMC article.
OBJECTIVES: Occupational noise-induced hearing loss (NIHL) due to industrial, military, and other job -related noise exposure can cause harmful health issues to occupied workers, but may also be potentially preventable. Vitamins/antioxidant have been studied as therapeutic …
OBJECTIVES: Occupational noise-induced hearing loss (NIHL) due to industrial, military, and other job -related noise exposure can cause harm …
Pharmacological Prevention of Noise-induced Hearing Loss: A Systematic Review.
Gupta A, Koochakzadeh S, Nguyen SA, Brennan EA, Meyer TA, Lambert PR. Gupta A, et al. Otol Neurotol. 2021 Jan;42(1):2-9. doi: 10.1097/MAO.0000000000002858. Otol Neurotol. 2021. PMID: 33229875 Free PMC article.
OBJECTIVE: This study aims to explore and determine the effectiveness of current pharmacologic agents for the prevention of noise-induced hearing loss (NIHL) via a systematic review. ...Initial data from this study alongside future clinical trials might potentially contrib …
OBJECTIVE: This study aims to explore and determine the effectiveness of current pharmacologic agents for the prevention of noise-ind …
Role of nutrition in the development and prevention of age-related hearing loss: A scoping review.
Rodrigo L, Campos-Asensio C, Rodríguez MÁ, Crespo I, Olmedillas H. Rodrigo L, et al. J Formos Med Assoc. 2021 Jan;120(1 Pt 1):107-120. doi: 10.1016/j.jfma.2020.05.011. Epub 2020 May 28. J Formos Med Assoc. 2021. PMID: 32473863 Free article. Review.
Diets rich in saturated fats and cholesterol have deleterious effects on hearing that could be prevented by lower consumption. Conversely, greater consumption of fruit and vegetables, and of polyunsaturated fatty acids (omega-3) and anti-oxidants in the form of vitamins A, …
Diets rich in saturated fats and cholesterol have deleterious effects on hearing that could be prevented by lower consumption. Conver …
Advances in genome editing for genetic hearing loss.
Ding N, Lee S, Lieber-Kotz M, Yang J, Gao X. Ding N, et al. Adv Drug Deliv Rev. 2021 Jan;168:118-133. doi: 10.1016/j.addr.2020.05.001. Epub 2020 May 7. Adv Drug Deliv Rev. 2021. PMID: 32387678 Free PMC article. Review.
It is estimated that genetic factors contribute to the causation of approximately 50% of congenital hearing loss. Yet, curative approaches to reversing or preventing genetic hearing impairment are still limited. The clustered regularly interspaced short palindromic repeats …
It is estimated that genetic factors contribute to the causation of approximately 50% of congenital hearing loss. Yet, curative approaches t …
Approach to hearing loss.
Newsted D, Rosen E, Cooke B, Beyea MM, Simpson MTW, Beyea JA. Newsted D, et al. Can Fam Physician. 2020 Nov;66(11):803-809. Can Fam Physician. 2020. PMID: 33208419 Free PMC article. Review.
Frequently, referral or urgent workup, including imaging, is necessary to confirm a patient's diagnosis and initiate management in order to prevent further complications....
Frequently, referral or urgent workup, including imaging, is necessary to confirm a patient's diagnosis and initiate management in order to …
An overview of occupational noise-induced hearing loss among workers: epidemiology, pathogenesis, and preventive measures.
Chen KH, Su SB, Chen KT. Chen KH, et al. Environ Health Prev Med. 2020 Oct 31;25(1):65. doi: 10.1186/s12199-020-00906-0. Environ Health Prev Med. 2020. PMID: 33129267 Free PMC article. Review.
The goal of this study was to review the epidemiology, pathogenesis, and preventive measures of ONIHL among workers and provide evidence for the implementation of control measures. ...Noise exposure may contribute to temporary or permanent threshold shifts; however, even t …
The goal of this study was to review the epidemiology, pathogenesis, and preventive measures of ONIHL among workers and provide evide …
The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer.
Zaharija B, Samardžija B, Bradshaw NJ. Zaharija B, et al. Molecules. 2020 Oct 27;25(21):4967. doi: 10.3390/molecules25214967. Molecules. 2020. PMID: 33121024 Free PMC article. Review.
TRIOBP-1 (also known as TARA or TAP68) is a mainly structured protein that is ubiquitously expressed and binds to F-actin, preventing its depolymerization. It has been shown to be important for many processes including in the cell cycle, adhesion junctions, and neuronal di …
TRIOBP-1 (also known as TARA or TAP68) is a mainly structured protein that is ubiquitously expressed and binds to F-actin, preventing …
New trends in the prevention of occupational noise-induced hearing loss.
Sliwinska-Kowalska M. Sliwinska-Kowalska M. Int J Occup Med Environ Health. 2020 Oct 20;33(6):841-848. doi: 10.13075/ijomeh.1896.01600. Epub 2020 Sep 29. Int J Occup Med Environ Health. 2020. PMID: 32994587 Free article. Review.
This paper reviews recent research on the effects of noise on hearing in pursuit of more effective methods for the prevention of occupational NIHL. The paper discusses the translational significance of noise-induced cochlear neuropathy, as recently shown in animals, and th …
This paper reviews recent research on the effects of noise on hearing in pursuit of more effective methods for the prevention of occu …
Noise Induced Hearing Loss and Tinnitus-New Research Developments and Remaining Gaps in Disease Assessment, Treatment, and Prevention.
Wang TC, Chang TY, Tyler R, Lin YJ, Liang WM, Shau YW, Lin WY, Chen YW, Lin CD, Tsai MH. Wang TC, et al. Brain Sci. 2020 Oct 13;10(10):732. doi: 10.3390/brainsci10100732. Brain Sci. 2020. PMID: 33066210 Free PMC article. Review.
Increasing knowledge of neural plasticity and adaptive changes in the central auditory system suggest that NIHL is preventable and transient abnormalities may be reversable, although ongoing research in assessment and early detection of hearing difficulties is still urgent …
Increasing knowledge of neural plasticity and adaptive changes in the central auditory system suggest that NIHL is preventable and tr …
Phase 1 study to evaluate safety, tolerability and pharmacokinetics of a novel intra-tympanic administered thiosulfate to prevent cisplatin-induced hearing loss in cancer patients.
Viglietta V, Shi F, Hu QY, Ren Y, Keilty J, Wolff H, McCarthy R, Kropp J, Weber P, Soglia J. Viglietta V, et al. Invest New Drugs. 2020 Oct;38(5):1463-1471. doi: 10.1007/s10637-020-00918-1. Epub 2020 Mar 10. Invest New Drugs. 2020. PMID: 32157599 Free PMC article. Clinical Trial.
Ototoxicity and subsequent permanent hearing loss remain a serious dose-limiting side effect associated with cisplatin treatment. To date, no therapies have been approved to prevent or treat cisplatin-induced hearing loss (CIHL). Sodium thiosulfate effectively inactivates …
Ototoxicity and subsequent permanent hearing loss remain a serious dose-limiting side effect associated with cisplatin treatment. To date, n …
Which interventions increase hearing protection behaviors during noisy recreational activities? A systematic review.
Loughran MT, Lyons S, Plack CJ, Armitage CJ. Loughran MT, et al. BMC Public Health. 2020 Sep 13;20(1):1376. doi: 10.1186/s12889-020-09414-w. BMC Public Health. 2020. PMID: 32919462 Free PMC article.
CONCLUSIONS: Hearing loss and tinnitus due to recreational noise exposure are major public health concerns yet very few studies have examined preventive interventions. The present systematic review sets the agenda for the future development and testing of evidence-based in …
CONCLUSIONS: Hearing loss and tinnitus due to recreational noise exposure are major public health concerns yet very few studies have examine …
Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness.
Leake PA, Akil O, Lang H. Leake PA, et al. Hear Res. 2020 Sep 1;394:107955. doi: 10.1016/j.heares.2020.107955. Epub 2020 Apr 5. Hear Res. 2020. PMID: 32331858 Free PMC article. Review.
This review summarizes the evidence for the efficacy of exogenous NTs in preventing SGN degeneration after hearing loss and reviews the animal research to date suggesting that NT gene therapy can elicit long-term NT expression in the cochlea, resulting in significantly imp …
This review summarizes the evidence for the efficacy of exogenous NTs in preventing SGN degeneration after hearing loss and reviews t …
Diagnostic and therapeutic applications of genomic medicine in progressive, late-onset, nonsyndromic sensorineural hearing loss.
Jimenez JE, Nourbakhsh A, Colbert B, Mittal R, Yan D, Green CL, Nisenbaum E, Liu G, Bencie N, Rudman J, Blanton SH, Zhong Liu X. Jimenez JE, et al. Gene. 2020 Jul 15;747:144677. doi: 10.1016/j.gene.2020.144677. Epub 2020 Apr 15. Gene. 2020. PMID: 32304785 Free PMC article. Review.
Many gene therapy modalities that have proven efficacious in animal trials have potential to delay or prevent PNSHL in humans. The development of new treatment modalities for PNSHL will lead to improved quality of life of many affected individuals and their families....
Many gene therapy modalities that have proven efficacious in animal trials have potential to delay or prevent PNSHL in humans. The de …
Cochrane method for systematic review and meta-analysis of interventions to prevent occupational noise-induced hearing loss - abridged.
Tikka C, Verbeek J, Kateman E, Morata TC, Dreschler W, Ferrite S. Tikka C, et al. Codas. 2020 Apr 3;32(2):e20190127. doi: 10.1590/2317-1782/20192019127. eCollection 2020. Codas. 2020. PMID: 32267337 Free article.
Seventeen studies (84028 participants) evaluated hearing loss prevention programs. Better use of HPDs might reduce hearing loss but other components not (very low-quality evidence). CONCLUSION: Hearing loss prevention and interventions modestly reduce noise exposure …
Seventeen studies (84028 participants) evaluated hearing loss prevention programs. Better use of HPDs might reduce hearing loss but o …
Does Treating Hearing Loss in Older Adults Improve Cognitive Outcomes? A Review.
Amieva H, Ouvrard C. Amieva H, et al. J Clin Med. 2020 Mar 16;9(3):805. doi: 10.3390/jcm9030805. J Clin Med. 2020. PMID: 32188074 Free PMC article. Review.
Nevertheless, because hearing loss is suspected to account for 9% of dementia cases, and also because hearing loss is one of the few potentially modifiable factors from a dementia prevention perspective, the need to stimulate research to have clearer knowledge of the benef …
Nevertheless, because hearing loss is suspected to account for 9% of dementia cases, and also because hearing loss is one of the few potenti …
Classification of audiograms in the prevention of noise-induced hearing loss: A clinical perspective.
Musiba Z. Musiba Z. S Afr J Commun Disord. 2020 Mar 3;67(2):e1-e5. doi: 10.4102/sajcd.v67i2.691. S Afr J Commun Disord. 2020. PMID: 32129662 Free PMC article. Review.
Engineering controls are superior to hearing protection devices (HPDs) in prevention of occupational noise induced hearing loss (ONIHL), although the latter are more commonly used. ...
Engineering controls are superior to hearing protection devices (HPDs) in prevention of occupational noise induced hearing loss (ONIH …
Risk versus benefit: Should not audiologists assess this in the context of occupational noise-induced hearing loss in the mining industry?
Khoza-Shangase K, Moroe NF. Khoza-Shangase K, et al. S Afr J Commun Disord. 2020 Mar 3;67(2):e1-e9. doi: 10.4102/sajcd.v67i2.671. S Afr J Commun Disord. 2020. PMID: 32129658 Free PMC article. Review.
BACKGROUND: Hearing conservation programmes (HCPs) are an important aspect of occupational health efforts to prevent occupational noise-induced hearing loss (ONIHL). In low- and middle income (LAMI) countries, where the incidence of ONIHL is significant, it is important to …
BACKGROUND: Hearing conservation programmes (HCPs) are an important aspect of occupational health efforts to prevent occupational noi …
Different infusion durations for preventing platinum-induced hearing loss in children with cancer.
van As JW, van den Berg H, van Dalen EC. van As JW, et al. Cochrane Database Syst Rev. 2020 Jan 21;1(1):CD010885. doi: 10.1002/14651858.CD010885.pub5. Cochrane Database Syst Rev. 2020. PMID: 31961948 Free PMC article.
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different platinum infusion durations have been studied. ...OBJECTIVES: To assess the effects of different durations of plat …
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent th …
Deafness-Dystonia-Optic Neuronopathy Syndrome.
Tranebjærg L. Tranebjærg L. 2003 Feb 6 [updated 2019 Nov 21]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. 2003 Feb 6 [updated 2019 Nov 21]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. PMID: 20301395 Free Books & Documents. Review.
Physical medicine and rehabilitation, physical and occupational therapy to improve fine and gross motor skills and mobility, to prevent contractures, and to provide adaptive devices to improve activities of daily living. ...
Physical medicine and rehabilitation, physical and occupational therapy to improve fine and gross motor skills and mobility, to prevent …
Evidence Supporting the Hypothesis That Inflammation-Induced Vasospasm Is Involved in the Pathogenesis of Acquired Sensorineural Hearing Loss.
Eisenhut M. Eisenhut M. Int J Otolaryngol. 2019 Nov 6;2019:4367240. doi: 10.1155/2019/4367240. eCollection 2019. Int J Otolaryngol. 2019. PMID: 31781229 Free PMC article. Review.
It is related to aging, noise, infection, ototoxic drugs, and genetic defects. It is essential to identify reversible and preventable causes to be able to reduce the burden of this disease. ...There is mainly indirect evidence for vasospasm-associated sensorineural hearing …
It is related to aging, noise, infection, ototoxic drugs, and genetic defects. It is essential to identify reversible and preventable …
Developments in Bio-Inspired Nanomaterials for Therapeutic Delivery to Treat Hearing Loss.
Rathnam C, Chueng SD, Ying YM, Lee KB, Kwan K. Rathnam C, et al. Front Cell Neurosci. 2019 Nov 6;13:493. doi: 10.3389/fncel.2019.00493. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31780898 Free PMC article. Review.
However, hearing aids are ineffective if hair cells or spiral ganglion neurons are severely damaged, and cochlear implants are ineffective without properly functioning spiral ganglion neurons. As such, strategies that alleviate hearing loss by preventing degeneration or pr …
However, hearing aids are ineffective if hair cells or spiral ganglion neurons are severely damaged, and cochlear implants are ineffective w …
Use of the guinea pig in studies on the development and prevention of acquired sensorineural hearing loss, with an emphasis on noise.
Naert G, Pasdelou MP, Le Prell CG. Naert G, et al. J Acoust Soc Am. 2019 Nov;146(5):3743. doi: 10.1121/1.5132711. J Acoust Soc Am. 2019. PMID: 31795705 Free PMC article. Review.
This article reviews the use of the guinea pig in basic auditory research, provides detailed discussion of its use in studies on noise injury and other injuries leading to acquired sensorineural hearing loss, and lists some therapeutics assessed in these laboratory animal models …
This article reviews the use of the guinea pig in basic auditory research, provides detailed discussion of its use in studies on noise injur …
The chinchilla animal model for hearing science and noise-induced hearing loss.
Trevino M, Lobarinas E, Maulden AC, Heinz MG. Trevino M, et al. J Acoust Soc Am. 2019 Nov;146(5):3710. doi: 10.1121/1.5132950. J Acoust Soc Am. 2019. PMID: 31795699 Free PMC article. Review.
Based on the mechanistic insights from noise-exposure studies, chinchillas have also been used in pre-clinical drug studies for the prevention and rescue of noise-induced hearing loss. This review paper highlights the role of the chinchilla model in hearing science, its im …
Based on the mechanistic insights from noise-exposure studies, chinchillas have also been used in pre-clinical drug studies for the preve …
Noise-induced hearing loss: Translating risk from animal models to real-world environments.
Le Prell CG, Hammill TL, Murphy WJ. Le Prell CG, et al. J Acoust Soc Am. 2019 Nov;146(5):3646. doi: 10.1121/1.5133385. J Acoust Soc Am. 2019. PMID: 31795692 Free PMC article. Review.
Noise-induced hearing loss (NIHL) is a common injury for service members and civilians. Effective prevention of NIHL with drug agents would reduce the prevalence of NIHL. ...
Noise-induced hearing loss (NIHL) is a common injury for service members and civilians. Effective prevention of NIHL with drug agents …
Noise-induced hearing loss and its prevention: Integration of data from animal models and human clinical trials.
Le Prell CG, Hammill TL, Murphy WJ. Le Prell CG, et al. J Acoust Soc Am. 2019 Nov;146(5):4051. doi: 10.1121/1.5132951. J Acoust Soc Am. 2019. PMID: 31795668 Free PMC article. Review.
Animal models have been used to gain insight into the risk of noise-induced hearing loss (NIHL) and its potential prevention using investigational new drug agents. A number of compounds have yielded benefit in pre-clinical (animal) models. ...
Animal models have been used to gain insight into the risk of noise-induced hearing loss (NIHL) and its potential prevention using in …
Evaluation and Management of Patients with Diabetes and Hearing Loss.
Spankovich C, Yerraguntla K. Spankovich C, et al. Semin Hear. 2019 Nov;40(4):308-314. doi: 10.1055/s-0039-1697644. Epub 2019 Oct 9. Semin Hear. 2019. PMID: 31602094 Free PMC article. Review.
The purpose of this article is to provide recommendations for the prevention, screening, evaluation, and management of hearing loss in PWD....
The purpose of this article is to provide recommendations for the prevention, screening, evaluation, and management of hearing loss i …
Gene therapy for hearing loss.
Omichi R, Shibata SB, Morton CC, Smith RJH. Omichi R, et al. Hum Mol Genet. 2019 Oct 1;28(R1):R65-R79. doi: 10.1093/hmg/ddz129. Hum Mol Genet. 2019. PMID: 31227837 Free PMC article. Review.
Habilitation options typically focus on amplification using wearable or implantable devices; however exciting new gene-therapy-based strategies to restore and prevent SNHL are actively under investigation. Recent proof-of-principle studies demonstrate the potential therape …
Habilitation options typically focus on amplification using wearable or implantable devices; however exciting new gene-therapy-based strateg …
The Epidemiology of Deafness.
Sheffield AM, Smith RJH. Sheffield AM, et al. Cold Spring Harb Perspect Med. 2019 Sep 3;9(9):a033258. doi: 10.1101/cshperspect.a033258. Cold Spring Harb Perspect Med. 2019. PMID: 30249598 Free PMC article. Review.
We also discuss the disparity in hearing loss across the world, with more economically developed countries having overall lower rates of hearing loss compared with developing countries, and the opportunity to improve diagnosis, prevention, and treatment of this disorder... …
We also discuss the disparity in hearing loss across the world, with more economically developed countries having overall lower rates of hea …
What is noise-induced hearing loss?
Ding T, Yan A, Liu K. Ding T, et al. Br J Hosp Med (Lond). 2019 Sep 2;80(9):525-529. doi: 10.12968/hmed.2019.80.9.525. Br J Hosp Med (Lond). 2019. PMID: 31498679 Free article. Review.
More research is required to explore the pathogenesis and to better guide clinical practice. Preventative strategies, such as educating the public about hearing health, should be adopted to reduce the harm of noise-induced hearing loss....
More research is required to explore the pathogenesis and to better guide clinical practice. Preventative strategies, such as educati …
A Review of Hearing Loss Associated with Zika, Ebola, and Lassa Fever.
Ficenec SC, Schieffelin JS, Emmett SD. Ficenec SC, et al. Am J Trop Med Hyg. 2019 Sep;101(3):484-490. doi: 10.4269/ajtmh.18-0934. Am J Trop Med Hyg. 2019. PMID: 31333155 Free PMC article. Review.
This information is critical to understanding pathophysiology, preventing future cases of this disability, and improving quality of life after survival of infection....
This information is critical to understanding pathophysiology, preventing future cases of this disability, and improving quality of l …
Interventions for cisplatin-induced hearing loss in children and adolescents with cancer.
Freyer DR, Brock P, Knight K, Reaman G, Cabral S, Robinson PD, Sung L. Freyer DR, et al. Lancet Child Adolesc Health. 2019 Aug;3(8):578-584. doi: 10.1016/S2352-4642(19)30115-4. Epub 2019 May 31. Lancet Child Adolesc Health. 2019. PMID: 31160205 Free PMC article. Review.
The identification of preventive interventions that are safe and effective for cisplatin-induced ototoxicity is important, especially in children because hearing loss can impair speech-language acquisition development. ...
The identification of preventive interventions that are safe and effective for cisplatin-induced ototoxicity is important, especially …
New molecular therapies for the treatment of hearing loss.
Ma Y, Wise AK, Shepherd RK, Richardson RT. Ma Y, et al. Pharmacol Ther. 2019 Aug;200:190-209. doi: 10.1016/j.pharmthera.2019.05.003. Epub 2019 May 8. Pharmacol Ther. 2019. PMID: 31075354 Free PMC article. Review.
One of the more promising drug-based therapies is based on neurotrophic factors for the repair of the ribbon synapse after noise exposure, as well as preventing loss of primary auditory neurons and regrowth of the auditory neuron fibers after severe hearing loss. ...
One of the more promising drug-based therapies is based on neurotrophic factors for the repair of the ribbon synapse after noise exposure, a …
Local Drug Delivery for Prevention of Hearing Loss.
Rybak LP, Dhukhwa A, Mukherjea D, Ramkumar V. Rybak LP, et al. Front Cell Neurosci. 2019 Jul 9;13:300. doi: 10.3389/fncel.2019.00300. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31338024 Free PMC article. Review.
Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is challenging. Systemic drugs have to cross the blood-labyrinth barrier (BLB). ...This review summarizes the pharmacology of local drug delivery by intra-tympanic injection to …
Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is challenging. Systemic drugs have to c …
Age-related Hearing Loss and Dementia.
Chern A, Golub JS. Chern A, et al. Alzheimer Dis Assoc Disord. 2019 Jul-Sep;33(3):285-290. doi: 10.1097/WAD.0000000000000325. Alzheimer Dis Assoc Disord. 2019. PMID: 31335455 Free PMC article. Review.
A growing body of research has shown an independent association between age-related hearing loss (ARHL) and dementia, identifying ARHL as a compelling potential target in preventive strategies for dementia. However, a causal linkage between ARHL and dementia needs to be in …
A growing body of research has shown an independent association between age-related hearing loss (ARHL) and dementia, identifying ARHL as a …
Translating animal models to human therapeutics in noise-induced and age-related hearing loss.
Kujawa SG, Liberman MC. Kujawa SG, et al. Hear Res. 2019 Jun;377:44-52. doi: 10.1016/j.heares.2019.03.003. Epub 2019 Mar 15. Hear Res. 2019. PMID: 30903954 Free PMC article. Review.
Decades of study in animals and humans have clarified the cellular targets and perceptual consequences of these forms of hearing loss, and preclinical studies have led to the development of therapeutics designed to slow, prevent or reverse them. Here, we review the histopa …
Decades of study in animals and humans have clarified the cellular targets and perceptual consequences of these forms of hearing loss, and p …
Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.
van As JW, van den Berg H, van Dalen EC. van As JW, et al. Cochrane Database Syst Rev. 2019 May 7;5(5):CD009219. doi: 10.1002/14651858.CD009219.pub5. Cochrane Database Syst Rev. 2019. PMID: 31063591 Free PMC article.
One of the most significant adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different otoprotective medical interventions have been studied. ...We identified no eligible studies for other possible otoprotective me …
One of the most significant adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicit …
Mitochondria-Targeted Antioxidants for Treatment of Hearing Loss: A Systematic Review.
Fujimoto C, Yamasoba T. Fujimoto C, et al. Antioxidants (Basel). 2019 Apr 24;8(4):109. doi: 10.3390/antiox8040109. Antioxidants (Basel). 2019. PMID: 31022870 Free PMC article. Review.
Mitochondria-targeted antioxidants are expected to help in the prevention and/or treatment of diseases associated with mitochondrial dysfunction. ...
Mitochondria-targeted antioxidants are expected to help in the prevention and/or treatment of diseases associated with mitochondrial …
Congenital Deafness with Labyrinthine Aplasia, Microtia, and Microdontia.
Ordonez J, Tekin M. Ordonez J, et al. 2012 Sep 20 [updated 2019 Apr 4]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. 2012 Sep 20 [updated 2019 Apr 4]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. PMID: 22993869 Free Books & Documents. Review.
MANAGEMENT: Treatment of manifestations: Enrollment in appropriate early-intervention programs and educational programs for the hearing impaired; consideration of vibrotactile hearing devices or brain stem implants for individuals with complete labyrinthine aplasia; consideration …
MANAGEMENT: Treatment of manifestations: Enrollment in appropriate early-intervention programs and educational programs for the hearing impa …
Newborn and Infant Hearing Screening Facing Globally Growing Numbers of People Suffering from Disabling Hearing Loss.
Neumann K, Chadha S, Tavartkiladze G, Bu X, White KR. Neumann K, et al. Int J Neonatal Screen. 2019 Jan 18;5(1):7. doi: 10.3390/ijns5010007. eCollection 2019 Mar. Int J Neonatal Screen. 2019. PMID: 33072967 Free PMC article. Review.
This review article focuses on the importance of high-quality newborn and infant hearing screening (NIHS) programs as one strategy to ameliorate disabling hearing loss as a global health problem. Two WHO resolutions regarding the prevention of deafness and hearing loss hav …
This review article focuses on the importance of high-quality newborn and infant hearing screening (NIHS) programs as one strategy to amelio …
The role of community health workers in addressing the global burden of ear disease and hearing loss: a systematic scoping review of the literature.
O'Donovan J, Verkerk M, Winters N, Chadha S, Bhutta MF. O'Donovan J, et al. BMJ Glob Health. 2019 Mar 1;4(2):e001141. doi: 10.1136/bmjgh-2018-001141. eCollection 2019. BMJ Glob Health. 2019. PMID: 30899572 Free PMC article.
We performed a systematic scoping review to identify evidence on how CHWs are currently deployed in the prevention, screening, diagnosis, treatment and management of ear disease and hearing loss; methods to train and support CHWs in this context; and cost-effectiveness of …
We performed a systematic scoping review to identify evidence on how CHWs are currently deployed in the prevention, screening, diagno …
Role of microRNAs in inner ear development and hearing loss.
Mittal R, Liu G, Polineni SP, Bencie N, Yan D, Liu XZ. Mittal R, et al. Gene. 2019 Feb 20;686:49-55. doi: 10.1016/j.gene.2018.10.075. Epub 2018 Oct 31. Gene. 2019. PMID: 30389561 Free PMC article. Review.
MicroRNAs (miRNAs) have been shown to play a role in inner ear development and thus, may play a role in the development or prevention of hearing loss. In this paper, we review the mechanism of action of miRNAs in the auditory system. ...
MicroRNAs (miRNAs) have been shown to play a role in inner ear development and thus, may play a role in the development or prevention …
Development and Formative Assessment of the Hearing Loss Toolkit for Self-Management.
Arnold ML, Oree P, Sanchez V, Reed N, Chisolm T. Arnold ML, et al. Semin Hear. 2019 Feb;40(1):49-67. doi: 10.1055/s-0038-1676783. Epub 2019 Feb 5. Semin Hear. 2019. PMID: 30728649 Free PMC article. Review.
Department of Health and Human Services, the Centers for Disease Control and Prevention, and the Agency for Healthcare Research and Quality in a series of modules that address a variety of common problem areas reported by adults with hearing loss. ...
Department of Health and Human Services, the Centers for Disease Control and Prevention, and the Agency for Healthcare Research and Q …
Association of Nutritional Factors with Hearing Loss.
Jung SY, Kim SH, Yeo SG. Jung SY, et al. Nutrients. 2019 Feb 1;11(2):307. doi: 10.3390/nu11020307. Nutrients. 2019. PMID: 30717210 Free PMC article. Review.
Therefore, considering that multifactorial nutritional causes are responsible, in part, for HL, provision of proper guidelines for maintaining a proper nutritional status is expected to prevent some of the causes and burden of HL....
Therefore, considering that multifactorial nutritional causes are responsible, in part, for HL, provision of proper guidelines for maintaini …
Age-related hearing loss and cognitive decline - The potential mechanisms linking the two.
Uchida Y, Sugiura S, Nishita Y, Saji N, Sone M, Ueda H. Uchida Y, et al. Auris Nasus Larynx. 2019 Feb;46(1):1-9. doi: 10.1016/j.anl.2018.08.010. Epub 2018 Sep 1. Auris Nasus Larynx. 2019. PMID: 30177417 Free article. Review.
Results from a number of epidemiological and laboratory studies have demonstrated a significant link between ARHL and cognitive decline. The Lancet International Commission on Dementia, Prevention, Intervention, and Care has estimated that mid-life hearing loss, if elimina …
Results from a number of epidemiological and laboratory studies have demonstrated a significant link between ARHL and cognitive decline. The …
A randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck cancer.
Rolland V, Meyer F, Guitton MJ, Bussières R, Philippon D, Bairati I, Leclerc M, Côté M. Rolland V, et al. J Otolaryngol Head Neck Surg. 2019 Jan 16;48(1):4. doi: 10.1186/s40463-019-0327-x. J Otolaryngol Head Neck Surg. 2019. PMID: 30651130 Free PMC article. Clinical Trial.
The objective of the trial was to test the efficacy of trans-tympanic injections of a STS gel to prevent cisplatin-induced ototoxicity. METHODS: Eligible participants were newly diagnosed patients with stage III or IV squamous cell carcinoma of the mouth, oropharynx, hypop …
The objective of the trial was to test the efficacy of trans-tympanic injections of a STS gel to prevent cisplatin-induced ototoxicit …
Diagnosing and Preventing Hearing Loss in the Genomic Age.
McDermott JH, Molina-Ramírez LP, Bruce IA, Mahaveer A, Turner M, Miele G, Body R, Mahood R, Ulph F, MacLeod R, Harvey K, Booth N, Demain LAM, Wilson P, Black GC, Morton CC, Newman WG. McDermott JH, et al. Trends Hear. 2019 Jan-Dec;23:2331216519878983. doi: 10.1177/2331216519878983. Trends Hear. 2019. PMID: 31621509 Free PMC article. Review.
Sensorial frailty: age-related hearing loss and the risk of cognitive impairment and dementia in later life.
Panza F, Lozupone M, Sardone R, Battista P, Piccininni M, Dibello V, La Montagna M, Stallone R, Venezia P, Liguori A, Giannelli G, Bellomo A, Greco A, Daniele A, Seripa D, Quaranta N, Logroscino G. Panza F, et al. Ther Adv Chronic Dis. 2018 Nov 9;10:2040622318811000. doi: 10.1177/2040622318811000. eCollection 2019. Ther Adv Chronic Dis. 2018. PMID: 31452865 Free PMC article. Review.
However, ARHL may represent a modifiable condition and a possible target for secondary prevention of cognitive impairment in older age, social isolation, late-life depression, and frailty. ...
However, ARHL may represent a modifiable condition and a possible target for secondary prevention of cognitive impairment in older ag …
Fluctuating Sensorineural Hearing Loss.
Liu H, Zhou K, Zhang X, Peng KA. Liu H, et al. Audiol Neurootol. 2019;24(3):109-116. doi: 10.1159/000500658. Epub 2019 Jul 17. Audiol Neurootol. 2019. PMID: 31315108 Free article. Review.
Immediate measures at the onset of acute hearing loss include corticosteroid therapy, while preventative and chronic therapies, which can limit disease severity and frequency, vary based on the specific condition treated. ...
Immediate measures at the onset of acute hearing loss include corticosteroid therapy, while preventative and chronic therapies, which …
Efficacy of hearing conservation education programs for youth and young adults: a systematic review.
Khan KM, Bielko SL, McCullagh MC. Khan KM, et al. BMC Public Health. 2018 Nov 22;18(1):1286. doi: 10.1186/s12889-018-6198-7. BMC Public Health. 2018. PMID: 30466413 Free PMC article. Review.
METHODS: Studies reporting results of hearing conservation or hearing loss prevention programs with youth or young adults, using randomized controlled trials, quasi-experimental designs, experimental design, or qualitative research, and published in peer-reviewed journals …
METHODS: Studies reporting results of hearing conservation or hearing loss prevention programs with youth or young adults, using rand …
Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage.
Waqas M, Gao S, Iram-Us-Salam, Ali MK, Ma Y, Li W. Waqas M, et al. Neural Plast. 2018 Jul 15;2018:3170801. doi: 10.1155/2018/3170801. eCollection 2018. Neural Plast. 2018. PMID: 30123244 Free PMC article. Review.
The article also explains the recent hair cell protection strategies to prevent the damage and restore hearing function in mammals....
The article also explains the recent hair cell protection strategies to prevent the damage and restore hearing function in mammals... …
Different infusion durations for preventing platinum-induced hearing loss in children with cancer.
van As JW, van den Berg H, van Dalen EC. van As JW, et al. Cochrane Database Syst Rev. 2018 Jul 5;7(7):CD010885. doi: 10.1002/14651858.CD010885.pub4. Cochrane Database Syst Rev. 2018. PMID: 29975402 Free PMC article. Updated. Review.
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different platinum infusion durations have been studied. ...OBJECTIVES: To assess the effects of different durations of plat …
Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent th …
Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss.
Brock PR, Maibach R, Childs M, Rajput K, Roebuck D, Sullivan MJ, Laithier V, Ronghe M, Dall'Igna P, Hiyama E, Brichard B, Skeen J, Mateos ME, Capra M, Rangaswami AA, Ansari M, Rechnitzer C, Veal GJ, Covezzoli A, Brugières L, Perilongo G, Czauderna P, Morland B, Neuwelt EA. Brock PR, et al. N Engl J Med. 2018 Jun 21;378(25):2376-2385. doi: 10.1056/NEJMoa1801109. N Engl J Med. 2018. PMID: 29924955 Free PMC article. Clinical Trial.
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