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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 7
1988 18
1989 24
1990 20
1991 17
1992 19
1993 26
1994 25
1995 28
1996 32
1997 30
1998 26
1999 33
2000 24
2001 34
2002 37
2003 30
2004 37
2005 53
2006 39
2007 53
2008 67
2009 62
2010 70
2011 90
2012 81
2013 118
2014 193
2015 232
2016 214
2017 213
2018 237
2019 233
2020 205
2021 66
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2,346 results
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Page 1
Management of Patients With Aortic Valve Stenosis.
Kanwar A, Thaden JJ, Nkomo VT. Kanwar A, et al. Mayo Clin Proc. 2018 Apr;93(4):488-508. doi: 10.1016/j.mayocp.2018.01.020. Mayo Clin Proc. 2018. PMID: 29622096 Review.
With increased life expectancy and aging of the population, aortic stenosis is now one of the most common valvular heart diseases. Early recognition and management of aortic stenosis are of paramount importance because untreated symptomatic severe disease is …
With increased life expectancy and aging of the population, aortic stenosis is now one of the most common valvular heart diseases …
Mitral regurgitation.
Enriquez-Sarano M, Akins CW, Vahanian A. Enriquez-Sarano M, et al. Lancet. 2009 Apr 18;373(9672):1382-94. doi: 10.1016/S0140-6736(09)60692-9. Epub 2009 Apr 6. Lancet. 2009. PMID: 19356795 Review.
Mitral regurgitation affects more than 2 million people in the USA. The main causes are classified as degenerative (with valve prolapse) and ischaemic (ie, due to consequences of coronary disease) in developed countries, or rheumatic (in developing countries). ...Su …
Mitral regurgitation affects more than 2 million people in the USA. The main causes are classified as degenerative (with valve prolap …
Aortic Stenosis: Diagnosis and Treatment.
Grimard BH, Safford RE, Burns EL. Grimard BH, et al. Am Fam Physician. 2016 Mar 1;93(5):371-8. Am Fam Physician. 2016. PMID: 26926974 Free article. Review.
During the asymptomatic latent period, left ventricular hypertrophy and atrial augmentation of preload compensate for the increase in afterload caused by aortic stenosis. As the disease worsens, these compensatory mechanisms become inadequate, leading to symptoms of hea …
During the asymptomatic latent period, left ventricular hypertrophy and atrial augmentation of preload compensate for the increase in afterl …
Burden of valvular heart diseases: a population-based study.
Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Nkomo VT, et al. Lancet. 2006 Sep 16;368(9540):1005-11. doi: 10.1016/S0140-6736(06)69208-8. Lancet. 2006. PMID: 16980116
BACKGROUND: Valvular heart diseases are not usually regarded as a major public-health problem. ...FINDINGS: In the general population group, moderate or severe valve disease was identified in 615 adults. There was no difference in the frequency of such …
BACKGROUND: Valvular heart diseases are not usually regarded as a major public-health problem. ...FINDINGS: In the general pop …
Mitral Valve Regurgitation in the Contemporary Era: Insights Into Diagnosis, Management, and Future Directions.
El Sabbagh A, Reddy YNV, Nishimura RA. El Sabbagh A, et al. JACC Cardiovasc Imaging. 2018 Apr;11(4):628-643. doi: 10.1016/j.jcmg.2018.01.009. JACC Cardiovasc Imaging. 2018. PMID: 29622181 Free article. Review.
Mitral valve regurgitation (MR) is the most common valvular heart disease. Primary MR is a disease of the mitral valve apparatus, whereas secondary MR is a disease of the left ventricle. ...
Mitral valve regurgitation (MR) is the most common valvular heart disease. Primary MR is a disease of the mitral …
Mitral valve disease--current management and future challenges.
Nishimura RA, Vahanian A, Eleid MF, Mack MJ. Nishimura RA, et al. Lancet. 2016 Mar 26;387(10025):1324-34. doi: 10.1016/S0140-6736(16)00558-4. Lancet. 2016. PMID: 27025438 Review.
The field of mitral valve disease diagnosis and management is rapidly changing. New understanding of disease pathology and progression, with improvements in and increased use of sophisticated imaging modalities, have led to early diagnosis and complex treatme …
The field of mitral valve disease diagnosis and management is rapidly changing. New understanding of disease pathology …
Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications.
Prihadi EA, Delgado V, Leon MB, Enriquez-Sarano M, Topilsky Y, Bax JJ. Prihadi EA, et al. JACC Cardiovasc Imaging. 2019 Mar;12(3):491-499. doi: 10.1016/j.jcmg.2018.09.027. JACC Cardiovasc Imaging. 2019. PMID: 30846123 Free article. Review.
Primary TR is caused by an anatomical abnormality of the tricuspid valve apparatus. Secondary TR is caused by dilation of the tricuspid valve annulus, related to right ventricular (RV), or right atrial remodeling and increased RV pressures (often secondary to left-s …
Primary TR is caused by an anatomical abnormality of the tricuspid valve apparatus. Secondary TR is caused by dilation of the tricusp …
Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.
Avezum A, Lopes RD, Schulte PJ, Lanas F, Gersh BJ, Hanna M, Pais P, Erol C, Diaz R, Bahit MC, Bartunek J, De Caterina R, Goto S, Ruzyllo W, Zhu J, Granger CB, Alexander JH. Avezum A, et al. Circulation. 2015 Aug 25;132(8):624-32. doi: 10.1161/CIRCULATIONAHA.114.014807. Epub 2015 Jun 23. Circulation. 2015. PMID: 26106009 Clinical Trial.
METHODS AND RESULTS: We compared the effect of apixaban and warfarin on rates of stroke or systemic embolism, major bleeding, and death in patients with and without moderate or severe valvular heart disease using Cox proportional hazards modeling. Of the 18 201 pati …
METHODS AND RESULTS: We compared the effect of apixaban and warfarin on rates of stroke or systemic embolism, major bleeding, and death in p …
Sex differences in bicuspid aortic valve disease.
Kong WKF, Bax JJ, Michelena HI, Delgado V. Kong WKF, et al. Prog Cardiovasc Dis. 2020 Jul-Aug;63(4):452-456. doi: 10.1016/j.pcad.2020.06.004. Epub 2020 Jun 27. Prog Cardiovasc Dis. 2020. PMID: 32599025 Free article. Review.
Bicuspid aortic valve (BAV), the most frequent congenital heart disease, is characterized by an uneven distribution between sexes. ...In addition, BAV has a multifactorial inheritance, low penetrance and variable phenotypes that may lead to different form of …
Bicuspid aortic valve (BAV), the most frequent congenital heart disease, is characterized by an uneven distribution bet …
Clinical history and management of bicuspid aortic valve in children and adolescents.
Niaz T, Fernandes SM, Sanders SP, Michelena H, Hagler DJ. Niaz T, et al. Prog Cardiovasc Dis. 2020 Jul-Aug;63(4):425-433. doi: 10.1016/j.pcad.2020.05.012. Epub 2020 Jun 1. Prog Cardiovasc Dis. 2020. PMID: 32497585 Review.
Bicuspid aortic valve (BAV) is one of the most common congenital heart defects in children, adolescents and adults. ...Although the majority of long term complications associated with BAV manifest later in life, children and adolescents may present with early onset …
Bicuspid aortic valve (BAV) is one of the most common congenital heart defects in children, adolescents and adults. ...Althoug …
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