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1995 1
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159 results

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Page 1
Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage.
Sperry JL, Guyette FX, Cotton BA, Luther JF, Utarnachitt RB, Kutcher ME, Daley BJ, Peetz AB, Patel MB, Goodman MD, Claridge JA, Patel N, Harbrecht BG, Hashmi ZG, Zarychanski R, Neal MD, Yazer MH, Martin-Gill C, Vincent LE, Harner AM, Meyer DE, Latimer AJ, Robinson BR, McKnight CL, Hinckley WR, Miller KR, Jansen JO, Martin D, Fox EE, Rosario-Rivera BL, Wisniewski SR; TOWAR Study Group. Sperry JL, et al. N Engl J Med. 2026 Jun 18;394(23):2317-2328. doi: 10.1056/NEJMoa2602167. Epub 2026 May 18. N Engl J Med. 2026. PMID: 42150044 Free PMC article. Clinical Trial.
Whether transfusion with whole blood is more beneficial than transfusion with blood components is uncertain, as are the effects of the length of time that blood products are in storage between donation and transfusion. ...Mortality at 30 days was 25.9% …
Whether transfusion with whole blood is more beneficial than transfusion with blood components is uncertain, as are the effect …
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
Morrison JJ, Dubose JJ, Rasmussen TE, Midwinter MJ. Morrison JJ, et al. Arch Surg. 2012 Feb;147(2):113-9. doi: 10.1001/archsurg.2011.287. Epub 2011 Oct 17. Arch Surg. 2012. PMID: 22006852
OBJECTIVES: To characterize contemporary use of tranexamic acid (TXA) in combat injury and to assess the effect of its administration on total blood product use, thromboembolic complications, and mortality. ...This benefit was greatest in the group of patient …
OBJECTIVES: To characterize contemporary use of tranexamic acid (TXA) in combat injury and to assess the effect of its administration …
Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Lower Respiratory Infections and Antimicrobial Resistance Collaborators. GBD 2023 Lower Respiratory Infections and Antimicrobial Resistance Collaborators. Lancet Infect Dis. 2026 Apr;26(4):343-361. doi: 10.1016/S1473-3099(25)00689-9. Epub 2025 Dec 15. Lancet Infect Dis. 2026. PMID: 41412141
We modelled pathogen-specific case-fatality ratios (CFRs) for each age group and location using splined binomial regression to create internally consistent estimates of incidence and mortality proportions attributable to viral, fungal, parasitic, and bacterial pathogens. . …
We modelled pathogen-specific case-fatality ratios (CFRs) for each age group and location using splined binomial regression to create …
Initial management of haemorrhagic war casualties: tactical priorities and innovative approaches in modern and future warfare.
Jarrassier A, Boutonnet M, Duranteau J, Travers S, Prat N, Dubourg O, Pasquier P, Libert N. Jarrassier A, et al. Crit Care. 2025 Nov 28;29(1):509. doi: 10.1186/s13054-025-05752-6. Crit Care. 2025. PMID: 41316469 Free PMC article. Review.
Damage control resuscitation centres on early administration of blood products in a 1:1:1 ratio or when available, low-titer group O whole blood (LTOWB), combined with permissive hypotension and prevention of hypothermia. ...In cases of major haemorrha …
Damage control resuscitation centres on early administration of blood products in a 1:1:1 ratio or when available, low- …
Association of Prehospital Blood Product Transfusion During Medical Evacuation of Combat Casualties in Afghanistan With Acute and 30-Day Survival.
Shackelford SA, Del Junco DJ, Powell-Dunford N, Mazuchowski EL, Howard JT, Kotwal RS, Gurney J, Butler FK Jr, Gross K, Stockinger ZT. Shackelford SA, et al. JAMA. 2017 Oct 24;318(16):1581-1591. doi: 10.1001/jama.2017.15097. JAMA. 2017. PMID: 29067429 Free PMC article.
IMPORTANCE: Prehospital blood product transfusion in trauma care remains controversial due to poor-quality evidence and cost. ...CONCLUSIONS AND RELEVANCE: Among medically evacuated US military combat causalities in Afghanistan, blood product tr …
IMPORTANCE: Prehospital blood product transfusion in trauma care remains controversial due to poor-quality evidence and cost. …
Damage Control Resuscitation.
Cap AP, Pidcoke HF, Spinella P, Strandenes G, Borgman MA, Schreiber M, Holcomb J, Tien HC, Beckett AN, Doughty H, Woolley T, Rappold J, Ward K, Reade M, Prat N, Ausset S, Kheirabadi B, Benov A, Griffin EP, Corley JB, Simon CD, Fahie R, Jenkins D, Eastridge BJ, Stockinger Z. Cap AP, et al. Mil Med. 2018 Sep 1;183(suppl_2):36-43. doi: 10.1093/milmed/usy112. Mil Med. 2018. PMID: 30189070
Damage control resuscitation (DCR) is a strategy for resuscitating patients from hemorrhagic shock to rapidly restore homeostasis. Efforts are focused on blood product transfusion with whole blood or component therapy closely approximating whole blood, …
Damage control resuscitation (DCR) is a strategy for resuscitating patients from hemorrhagic shock to rapidly restore homeostasis. Efforts a …
A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Mahadevan M, Gopukumar K, Gupta R, Morde A, Patni P, Srinivas SS, Bhuvanendran A, Phanindra A. Mahadevan M, et al. Adv Ther. 2025 Oct;42(10):5238-5254. doi: 10.1007/s12325-025-03327-z. Epub 2025 Aug 28. Adv Ther. 2025. PMID: 40875185 Free PMC article. Clinical Trial.
Ashwagandha, an established adaptogen, is known to combat stress. We studied the safety and efficacy of Ashwagandha formulation, Zenroot (ZEN), containing 1.5% total withanolides on stress, anxiety, mood, and sleep quality in human subjects with non-chronic mild to modera …
Ashwagandha, an established adaptogen, is known to combat stress. We studied the safety and efficacy of Ashwagandha formulation, Zenr …
Prevalence of Trauma-Induced Hypocalcemia in the Prehospital Setting.
Brandt MD, Liccardi C, Heidle J, Woods TD, White C, Mullins JR, Blackwell J, Le LT, Brantley K. Brandt MD, et al. J Spec Oper Med. 2023 Jun 23;23(2):44-48. doi: 10.55460/WYEJ-1M3J. J Spec Oper Med. 2023. PMID: 37094288
Patients who received blood products prior to emergency department (ED) arrival were excluded from the study. ...The administration of a calcium supplement empirically in trauma patients from the prehospital environment and prior to blood transfusion is not r …
Patients who received blood products prior to emergency department (ED) arrival were excluded from the study. ...The administr …
Cell salvage for the management of postpartum haemorrhage.
Dey T, Brown D, Cole MG, Hill RA, Chaplin M, Huffstetler HE, Curtis F. Dey T, et al. Cochrane Database Syst Rev. 2024 Dec 20;12(12):CD016120. doi: 10.1002/14651858.CD016120. Cochrane Database Syst Rev. 2024. PMID: 39704317 Free PMC article.
Autologous cell salvage in the management of PPH has been proposed to combat limitations in access to allogenic blood and potential transfusion-related risks. ...AUTHORS' CONCLUSIONS: Cell salvage may reduce the need for allogenic blood transfusion, may reduc …
Autologous cell salvage in the management of PPH has been proposed to combat limitations in access to allogenic blood and pote …
Thrombosis in Coronavirus disease 2019 (COVID-19) through the prism of Virchow's triad.
Ahmed S, Zimba O, Gasparyan AY. Ahmed S, et al. Clin Rheumatol. 2020 Sep;39(9):2529-2543. doi: 10.1007/s10067-020-05275-1. Epub 2020 Jul 11. Clin Rheumatol. 2020. PMID: 32654082 Free PMC article. Review.
Stratifying risk of COVID-19 thromboses should be based on age, presence of comorbidities, D-dimer, CT scoring, and various blood cell ratios. Isolated heparin therapy may not be sufficient to combat thrombosis in this disease. ...Endothelial dysfunction, pla …
Stratifying risk of COVID-19 thromboses should be based on age, presence of comorbidities, D-dimer, CT scoring, and various blood cel …
159 results