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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1976 1
1977 1
1979 1
1980 4
1981 4
1983 1
1984 2
1985 2
1986 2
1987 7
1988 6
1989 6
1990 10
1991 6
1992 6
1993 6
1994 10
1995 20
1996 11
1997 31
1998 24
1999 35
2000 53
2001 79
2002 102
2003 128
2004 177
2005 190
2006 248
2007 302
2008 364
2009 397
2010 463
2011 499
2012 611
2013 678
2014 766
2015 891
2016 1011
2017 1019
2018 1079
2019 1113
2020 1316
2021 1411
2022 634
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12,231 results
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Page 1
Stem Cell Therapy for Diabetes: Beta Cells versus Pancreatic Progenitors.
Memon B, Abdelalim EM. Memon B, et al. Cells. 2020 Jan 23;9(2):283. doi: 10.3390/cells9020283. Cells. 2020. PMID: 31979403 Free PMC article. Review.
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. In order to replace the function of the destroyed pancreatic beta cells in diabetes, islet transplantation is the most widely practiced treatment. ...
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. In order to replace the function of the destroyed pan …
A Stem Cell Approach to Cure Type 1 Diabetes.
Helman A, Melton DA. Helman A, et al. Cold Spring Harb Perspect Biol. 2021 Jan 4;13(1):a035741. doi: 10.1101/cshperspect.a035741. Cold Spring Harb Perspect Biol. 2021. PMID: 32122884 Review.
While cadaveric islet transplantations coupled with immunosuppressants can cure diabetes, the scarcity of acceptable islets is problematic. Developmental research on pancreas formation has informed in vitro differentiation of human pluripotent stem cells into …
While cadaveric islet transplantations coupled with immunosuppressants can cure diabetes, the scarcity of acceptable islets is proble …
Generation of stem cell-derived β-cells from patients with type 1 diabetes.
Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Millman JR, et al. Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463. Nat Commun. 2016. PMID: 27163171 Free PMC article.
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells). Here we extend this approach to generate the first SC-beta cells from type 1 diabetic patients (T1D). beta-cells are destroy …
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells) …
Mesenchymal stem cells to treat type 1 diabetes.
Pixley JS. Pixley JS. Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165315. doi: 10.1016/j.bbadis.2018.10.033. Epub 2018 Nov 30. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 30508575 Free article. Review.
This review is an effort to meld our preclinical observations with others for the reader and to outline potential avenues to improve the present outlook for patients with diabetes. This effort exams the history or background of stem cell research in the labor …
This review is an effort to meld our preclinical observations with others for the reader and to outline potential avenues to improve the pre …
Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?
Bourgeois S, Sawatani T, Van Mulders A, De Leu N, Heremans Y, Heimberg H, Cnop M, Staels W. Bourgeois S, et al. Cells. 2021 Jan 19;10(1):191. doi: 10.3390/cells10010191. Cells. 2021. PMID: 33477961 Free PMC article. Review.
However, donor shortage hinders the widespread implementation of this therapy. Human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells, represent an attractive alternative beta cell source fo …
However, donor shortage hinders the widespread implementation of this therapy. Human pluripotent stem cells, including embryon …
The journey of islet cell transplantation and future development.
Gamble A, Pepper AR, Bruni A, Shapiro AMJ. Gamble A, et al. Islets. 2018 Mar 4;10(2):80-94. doi: 10.1080/19382014.2018.1428511. Epub 2018 Feb 5. Islets. 2018. PMID: 29394145 Free PMC article. Review.
Protective strategies are being tested to circumvent several of these events including exploration of alternative transplantation sites, stem cell-derived insulin producing cell therapies, co-transplantation with mesenchymal stem cells or explor …
Protective strategies are being tested to circumvent several of these events including exploration of alternative transplantation sites, …
Mesenchymal stem cell-based therapy for type 1 diabetes.
Wu H, Mahato RI. Wu H, et al. Discov Med. 2014 Mar;17(93):139-43. Discov Med. 2014. PMID: 24641956 Free article. Review.
Type 1 diabetes (T1D), traditionally termed "juvenile diabetes" because of an early onset age, is affecting 5-10% of total diabetic population. ...Mesenchymal stem cell (MSC) based cell therapy is among one of them. MSCs are a type of adult s …
Type 1 diabetes (T1D), traditionally termed "juvenile diabetes" because of an early onset age, is affecting 5-10% of total dia …
Stem cells in the treatment of diabetes mellitus - Focus on mesenchymal stem cells.
Päth G, Perakakis N, Mantzoros CS, Seufert J. Päth G, et al. Metabolism. 2019 Jan;90:1-15. doi: 10.1016/j.metabol.2018.10.005. Epub 2018 Oct 18. Metabolism. 2019. PMID: 30342065 Review.
Diabetes mellitus type 1 and type 2 have become a global epidemic with dramatically increasing incidences. ...Beside traditional treatment with insulin and oral anti-diabetic drugs, clinicians try to improve patient's care by cell therapies using embryonic …
Diabetes mellitus type 1 and type 2 have become a global epidemic with dramatically increasing incidences. ...Beside tradition …
Identifying the Therapeutic Significance of Mesenchymal Stem Cells.
Mishra VK, Shih HH, Parveen F, Lenzen D, Ito E, Chan TF, Ke LY. Mishra VK, et al. Cells. 2020 May 6;9(5):1145. doi: 10.3390/cells9051145. Cells. 2020. PMID: 32384763 Free PMC article. Review.
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due to their immense potential for immunosuppression and their therapeutic role in immune disorders. ...Also, we sum up the results of the enhancement, utilization, and therapeutic …
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due to their immense potential for immun …
iPSC technology-based regenerative therapy for diabetes.
Kondo Y, Toyoda T, Inagaki N, Osafune K. Kondo Y, et al. J Diabetes Investig. 2018 Mar;9(2):234-243. doi: 10.1111/jdi.12702. Epub 2017 Jul 29. J Diabetes Investig. 2018. PMID: 28609558 Free PMC article. Review.
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), into pancreatic endocrine lineages has been vigorously examined by reproducing the in vivo dev …
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) and induced p …
12,231 results
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