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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1971 1
1975 1
1976 1
1977 1
1979 1
1980 4
1981 4
1983 1
1984 2
1985 2
1986 2
1987 7
1988 6
1989 6
1990 10
1991 6
1992 6
1993 8
1994 10
1995 20
1996 11
1997 31
1998 25
1999 35
2000 53
2001 79
2002 102
2003 129
2004 178
2005 190
2006 248
2007 302
2008 364
2009 397
2010 463
2011 498
2012 610
2013 679
2014 766
2015 891
2016 1011
2017 1019
2018 1075
2019 1110
2020 1315
2021 1405
2022 1281
2023 1249
2024 596

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14,454 results

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Page 1
Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes.
Hogrebe NJ, Ishahak M, Millman JR. Hogrebe NJ, et al. Cell Stem Cell. 2023 May 4;30(5):530-548. doi: 10.1016/j.stem.2023.04.002. Cell Stem Cell. 2023. PMID: 37146579 Free PMC article. Review.
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs) has the potential to provide an unlimited source of insulin-producing beta cells for the treatment of diabetes. In order for this cell therapy to become wi …
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs) has the potential to provide an unli …
Stem Cell Therapy for Diabetes: Beta Cells versus Pancreatic Progenitors.
Memon B, Abdelalim EM. Memon B, et al. Cells. 2020 Jan 23;9(2):283. doi: 10.3390/cells9020283. Cells. 2020. PMID: 31979403 Free PMC article. Review.
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. ...However, it has several limitations. As an alternative approach, human pluripotent stem cells (hPSCs) can provide an unlimited source of pancreatic cells that have the a
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. ...However, it has several limitations. As an alterna
Mesenchymal stem cells to treat type 1 diabetes.
Pixley JS. Pixley JS. Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165315. doi: 10.1016/j.bbadis.2018.10.033. Epub 2018 Nov 30. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 30508575 Free article. Review.
This review is an effort to meld our preclinical observations with others for the reader and to outline potential avenues to improve the present outlook for patients with diabetes. This effort exams the history or background of stem cell research in the labor …
This review is an effort to meld our preclinical observations with others for the reader and to outline potential avenues to improve the pre …
Stem cells in the treatment of diabetes mellitus - Focus on mesenchymal stem cells.
Päth G, Perakakis N, Mantzoros CS, Seufert J. Päth G, et al. Metabolism. 2019 Jan;90:1-15. doi: 10.1016/j.metabol.2018.10.005. Epub 2018 Oct 18. Metabolism. 2019. PMID: 30342065 Review.
Diabetes mellitus type 1 and type 2 have become a global epidemic with dramatically increasing incidences. ...Beside traditional treatment with insulin and oral anti-diabetic drugs, clinicians try to improve patient's care by cell therapies using embryonic
Diabetes mellitus type 1 and type 2 have become a global epidemic with dramatically increasing incidences. ...Beside tradition
Identifying the Therapeutic Significance of Mesenchymal Stem Cells.
Mishra VK, Shih HH, Parveen F, Lenzen D, Ito E, Chan TF, Ke LY. Mishra VK, et al. Cells. 2020 May 6;9(5):1145. doi: 10.3390/cells9051145. Cells. 2020. PMID: 32384763 Free PMC article. Review.
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due to their immense potential for immunosuppression and their therapeutic role in immune disorders. ...Also, we sum up the results of the enhancement, utilization, and therapeutic …
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due to their immense potential for immun …
Generation of stem cell-derived beta-cells from patients with type 1 diabetes.
Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Millman JR, et al. Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463. Nat Commun. 2016. PMID: 27163171 Free PMC article.
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells). Here we extend this approach to generate the first SC-beta cells from type 1 diabetic patients (T1D). beta-cells are destroy …
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells) …
Adipose-derived Mesenchymal Stem Cells Therapy as a new Treatment Option for Diabetes Mellitus.
Mikłosz A, Chabowski A. Mikłosz A, et al. J Clin Endocrinol Metab. 2023 Jul 14;108(8):1889-1897. doi: 10.1210/clinem/dgad142. J Clin Endocrinol Metab. 2023. PMID: 36916961 Free PMC article. Review.
Among different treatment options for diabetes, adipose-derived mesenchymal stem cells (ADMSCs) therapy attract the most attention. ...Nevertheless, transplantation of mesenchymal stem cells is associated with certain risks; therefore recently m …
Among different treatment options for diabetes, adipose-derived mesenchymal stem cells (ADMSCs) therapy attract the mos …
Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?
Bourgeois S, Sawatani T, Van Mulders A, De Leu N, Heremans Y, Heimberg H, Cnop M, Staels W. Bourgeois S, et al. Cells. 2021 Jan 19;10(1):191. doi: 10.3390/cells10010191. Cells. 2021. PMID: 33477961 Free PMC article. Review.
However, donor shortage hinders the widespread implementation of this therapy. Human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells, represent an attractive alternative beta cell source fo …
However, donor shortage hinders the widespread implementation of this therapy. Human pluripotent stem cells, including embryon …
Towards a better understanding of diabetes mellitus using organoid models.
Beydag-Tasöz BS, Yennek S, Grapin-Botton A. Beydag-Tasöz BS, et al. Nat Rev Endocrinol. 2023 Apr;19(4):232-248. doi: 10.1038/s41574-022-00797-x. Epub 2023 Jan 20. Nat Rev Endocrinol. 2023. PMID: 36670309 Free PMC article. Review.
Our understanding of diabetes mellitus has benefited from a combination of clinical investigations and work in model organisms and cell lines. ...Organoids can be derived from human tissue cells or pluripotent stem cells and enable the pr …
Our understanding of diabetes mellitus has benefited from a combination of clinical investigations and work in model organisms …
The promise of CRISPR/Cas9 technology in diabetes mellitus therapy: How gene editing is revolutionizing diabetes research and treatment.
Cheng Y, Wang H, Li M. Cheng Y, et al. J Diabetes Complications. 2023 Aug;37(8):108524. doi: 10.1016/j.jdiacomp.2023.108524. Epub 2023 Jun 2. J Diabetes Complications. 2023. PMID: 37295292 Review.
Diabetes mellitus is a metabolic disease, characterized by chronic hyperglycemia caused by an abnormality in insulin secretion or action. Millions of people across the world are affected by diabetes mellitus which has serious implications for their hea
Diabetes mellitus is a metabolic disease, characterized by chronic hyperglycemia caused by an abnormality in insulin secretion
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