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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1976 1
1977 1
1979 1
1980 4
1981 4
1983 1
1984 2
1985 2
1986 2
1987 7
1988 6
1989 6
1990 10
1991 6
1992 6
1993 7
1994 10
1995 20
1996 11
1997 31
1998 24
1999 35
2000 54
2001 79
2002 102
2003 128
2004 177
2005 190
2006 248
2007 302
2008 364
2009 397
2010 463
2011 497
2012 609
2013 675
2014 765
2015 888
2016 1009
2017 1014
2018 1072
2019 1086
2020 1062
2021 6
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10,179 results
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Page 1
Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges.
Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Sneddon JB, et al. Cell Stem Cell. 2018 Jun 1;22(6):810-823. doi: 10.1016/j.stem.2018.05.016. Cell Stem Cell. 2018. PMID: 29859172 Free PMC article. Review.
Restoration of insulin independence and normoglycemia has been the overarching goal in diabetes research and therapy. While whole-organ and islet transplantation have become gold-standard procedures in achieving glucose control in diabetic patients, the profound lack of su …
Restoration of insulin independence and normoglycemia has been the overarching goal in diabetes research and therapy. While whole-org …
Generation of stem cell-derived beta-cells from patients with type 1 diabetes.
Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Millman JR, et al. Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463. Nat Commun. 2016. PMID: 27163171 Free PMC article.
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells). Here we extend this approach to generate the first SC-beta cells from type 1 diabetic patients (T1D). beta-cells are destroy …
We recently reported the scalable in vitro production of functional stem cell-derived beta-cells (SC-beta cells) …
Mesenchymal stem cells and type 1 diabetes treatment.
Boháčová P, Holáň V. Boháčová P, et al. Vnitr Lek. 2018 Fall;64(7-8):725-728. Vnitr Lek. 2018. PMID: 30441979 Review. English.
For those reasons, new approaches of treatment are being searched, the using of mesenchymal stem cells (MSCs) envisions a promising tool for cell-based therapy of type 1 diabetes. ...Key words: autoimmune reaction - differentiation - mesenchymal ste …
For those reasons, new approaches of treatment are being searched, the using of mesenchymal stem cells (MSCs) envisions a prom …
Autologous Pluripotent Stem Cell-Derived beta-Like Cells for Diabetes Cellular Therapy.
Millman JR, Pagliuca FW. Millman JR, et al. Diabetes. 2017 May;66(5):1111-1120. doi: 10.2337/db16-1406. Diabetes. 2017. PMID: 28507211 Free article. Review.
Development of stem cell technologies for cell replacement therapy has progressed rapidly in recent years. Diabetes has long been seen as one of the first applications for stem cell-derived cells because of the loss of only a singl …
Development of stem cell technologies for cell replacement therapy has progressed rapidly in recent years. Diabetes …
The journey of islet cell transplantation and future development.
Gamble A, Pepper AR, Bruni A, Shapiro AMJ. Gamble A, et al. Islets. 2018 Mar 4;10(2):80-94. doi: 10.1080/19382014.2018.1428511. Epub 2018 Feb 5. Islets. 2018. PMID: 29394145 Free PMC article. Review.
Protective strategies are being tested to circumvent several of these events including exploration of alternative transplantation sites, stem cell-derived insulin producing cell therapies, co-transplantation with mesenchymal stem cells or explor …
Protective strategies are being tested to circumvent several of these events including exploration of alternative transplantation sites, …
Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving beta-Cell Destruction.
Sun Y, Shi H, Yin S, Ji C, Zhang X, Zhang B, Wu P, Shi Y, Mao F, Yan Y, Xu W, Qian H. Sun Y, et al. ACS Nano. 2018 Aug 28;12(8):7613-7628. doi: 10.1021/acsnano.7b07643. Epub 2018 Aug 7. ACS Nano. 2018. PMID: 30052036
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to alleviate diabetes mellitus (DM) in both animal models and clinical trials. ...Ta …
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue regeneration and injury repair as mesenchymal stem …
Mesenchymal stem cell-based therapy for type 1 diabetes.
Wu H, Mahato RI. Wu H, et al. Discov Med. 2014 Mar;17(93):139-43. Discov Med. 2014. PMID: 24641956 Free article. Review.
Type 1 diabetes (T1D), traditionally termed "juvenile diabetes" because of an early onset age, is affecting 5-10% of total diabetic population. ...Mesenchymal stem cell (MSC) based cell therapy is among one of them. MSCs are a type of adult s …
Type 1 diabetes (T1D), traditionally termed "juvenile diabetes" because of an early onset age, is affecting 5-10% of total dia …
mTOR signaling in stem and progenitor cells.
Meng D, Frank AR, Jewell JL. Meng D, et al. Development. 2018 Jan 8;145(1):dev152595. doi: 10.1242/dev.152595. Development. 2018. PMID: 29311260 Free PMC article. Review.
Recently, however, new studies have demonstrated important roles for mTOR in promoting the differentiation of adult stem cells, driving the growth and proliferation of stem and progenitor cells, and dictating the differentiation program of multipotent …
Recently, however, new studies have demonstrated important roles for mTOR in promoting the differentiation of adult stem cells …
Mesenchymal Stem Cells as New Therapeutic Approach for Diabetes and Pancreatic Disorders.
Scuteri A, Monfrini M. Scuteri A, et al. Int J Mol Sci. 2018 Sep 16;19(9):2783. doi: 10.3390/ijms19092783. Int J Mol Sci. 2018. PMID: 30223606 Free PMC article. Review.
Current therapies are able to adjust insulin levels according to blood glucose peak, but they only partly reach the goal to abrogate the consequent inflammatory milieu responsible for diabetes-related diseases. In recent years, many studies have investigated the possible u …
Current therapies are able to adjust insulin levels according to blood glucose peak, but they only partly reach the goal to abrogate the con …
Therapeutic potential of mesenchymal stem cells for diabetes.
Moreira A, Kahlenberg S, Hornsby P. Moreira A, et al. J Mol Endocrinol. 2017 Oct;59(3):R109-R120. doi: 10.1530/JME-17-0117. Epub 2017 Jul 24. J Mol Endocrinol. 2017. PMID: 28739632 Free PMC article. Review.
Mesenchymal stem cells (MSCs) are self-renewing multipotent cells that have the capacity to secrete multiple biologic factors that can restore and repair injured tissues. ...Experimental and clinical studies have provided promising results using MSCs to treat …
Mesenchymal stem cells (MSCs) are self-renewing multipotent cells that have the capacity to secrete multiple biologic f …
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