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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 3
2004 2
2005 4
2006 4
2007 4
2008 5
2009 15
2010 11
2011 9
2012 13
2013 19
2014 19
2015 18
2016 19
2017 32
2018 35
2019 39
2020 30
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256 results
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Page 1
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.
Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Watanabe S, Williams KJN, Flozak AS, Nicholson TT, Morgan VK, Winter DR, Hinchcliff M, Hrusch CL, Guzy RD, Bonham CA, Sperling AI, Bag R, Hamanaka RB, Mutlu GM, Yeldandi AV, Marshall SA, Shilatifard A, Amaral LAN, Perlman H, Sznajder JI, Argento AC, Gillespie CT, Dematte J, Jain M, Singer BD, Ridge KM, Lam AP, Bharat A, Bhorade SM, Gottardi CJ, Budinger GRS, Misharin AV. Reyfman PA, et al. Am J Respir Crit Care Med. 2019 Jun 15;199(12):1517-1536. doi: 10.1164/rccm.201712-2410OC. Am J Respir Crit Care Med. 2019. PMID: 30554520 Free PMC article.
Methods: We performed single-cell RNA sequencing on lung tissue obtained from eight transplant donors and eight recipients with pulmonary fibrosis and on one bronchoscopic cryobiospy sample from a patient with idiopathic pulmonary fibrosis. ...W …
Methods: We performed single-cell RNA sequencing on lung tissue obtained from eight transplant donors and eight recipients with pulmonary
Mesenchymal stem cells in idiopathic pulmonary fibrosis.
Li X, Yue S, Luo Z. Li X, et al. Oncotarget. 2017 May 23;8(60):102600-102616. doi: 10.18632/oncotarget.18126. eCollection 2017 Nov 24. Oncotarget. 2017. PMID: 29254275 Free PMC article. Review.
Idiopathic pulmonary fibrosis (IPF) is a major cause of respiratory failure in critically ill patients and common outcome of various lung interstitial diseases. ...As such, the administration of mesenchymal stem or stromal cells (MSCs) is curren
Idiopathic pulmonary fibrosis (IPF) is a major cause of respiratory failure in critically ill patients and common outco
Allogeneic Human Mesenchymal Stem Cells in Patients With Idiopathic Pulmonary Fibrosis via Intravenous Delivery (AETHER): A Phase I Safety Clinical Trial.
Glassberg MK, Minkiewicz J, Toonkel RL, Simonet ES, Rubio GA, DiFede D, Shafazand S, Khan A, Pujol MV, LaRussa VF, Lancaster LH, Rosen GD, Fishman J, Mageto YN, Mendizabal A, Hare JM. Glassberg MK, et al. Chest. 2017 May;151(5):971-981. doi: 10.1016/j.chest.2016.10.061. Epub 2016 Nov 24. Chest. 2017. PMID: 27890713 Free PMC article. Clinical Trial.
BACKGROUND: Despite Food and Drug Administration approval of 2 new drugs for idiopathic pulmonary fibrosis (IPF), curative therapies remain elusive and mortality remains high. ...The Allogeneic Human Cells (hMSC) in patients with Idiopathic P
BACKGROUND: Despite Food and Drug Administration approval of 2 new drugs for idiopathic pulmonary fibrosis (IPF), curat …
Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.
Liang J, Zhang Y, Xie T, Liu N, Chen H, Geng Y, Kurkciyan A, Mena JM, Stripp BR, Jiang D, Noble PW. Liang J, et al. Nat Med. 2016 Nov;22(11):1285-1293. doi: 10.1038/nm.4192. Epub 2016 Oct 3. Nat Med. 2016. PMID: 27694932 Free PMC article.
Type 2 alveolar epithelial cells (AEC2s) are stem cells in the adult lung that contribute to the lung repair process. The mechanisms that regulate AEC2 renewal are incompletely understood. ...Furthermore, AEC2s from patients with severe pulmonary fi
Type 2 alveolar epithelial cells (AEC2s) are stem cells in the adult lung that contribute to the lung repair process. T …
Stem Cell and Idiopathic Pulmonary Fibrosis: Mechanisms and Treatment.
Liu M, Ren D, Wu D, Zheng J, Tu W. Liu M, et al. Curr Stem Cell Res Ther. 2015;10(6):466-76. doi: 10.2174/1574888x10666150519092639. Curr Stem Cell Res Ther. 2015. PMID: 25986617 Review.
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease resulting from multiplex causes. Evidence indicates that stem/progenitor cells might play a key role in IPF pathogenesis and repair, which may provide some novel potent
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease resulting from multiplex causes. Evidence
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.
Lehmann M, Buhl L, Alsafadi HN, Klee S, Hermann S, Mutze K, Ota C, Lindner M, Behr J, Hilgendorff A, Wagner DE, Königshoff M. Lehmann M, et al. Respir Res. 2018 Sep 15;19(1):175. doi: 10.1186/s12931-018-0876-y. Respir Res. 2018. PMID: 30219058 Free PMC article.
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to fibroblast activation, extracellular ma …
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogrammi …
Mesenchymal Stem Cells for the Treatment of Idiopathic Pulmonary Fibrosis.
Tzouvelekis A, Toonkel R, Karampitsakos T, Medapalli K, Ninou I, Aidinis V, Bouros D, Glassberg MK. Tzouvelekis A, et al. Front Med (Lausanne). 2018 May 15;5:142. doi: 10.3389/fmed.2018.00142. eCollection 2018. Front Med (Lausanne). 2018. PMID: 29868594 Free PMC article. Review.
Idiopathic pulmonary fibrosis (IPF) is an inexorably progressive lung disease of unknown origin. Prognosis is poor, with limited treatment options available, and the median survival remains just 3-5 years. ...Promising results of preclinical studies using mes
Idiopathic pulmonary fibrosis (IPF) is an inexorably progressive lung disease of unknown origin. Prognosis is poor, wit
Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling.
Wilkinson DC, Alva-Ornelas JA, Sucre JM, Vijayaraj P, Durra A, Richardson W, Jonas SJ, Paul MK, Karumbayaram S, Dunn B, Gomperts BN. Wilkinson DC, et al. Stem Cells Transl Med. 2017 Feb;6(2):622-633. doi: 10.5966/sctm.2016-0192. Epub 2016 Sep 15. Stem Cells Transl Med. 2017. PMID: 28191779 Free PMC article.
Here, we present a method for the generation of self-assembled human lung tissue and its potential for disease modeling and drug discovery for lung diseases characterized by progressive and irreversible scarring such as idiopathic pulmonary fibrosis (IPF). .. …
Here, we present a method for the generation of self-assembled human lung tissue and its potential for disease modeling and drug discovery f …
Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells.
Wu H, Yu Y, Huang H, Hu Y, Fu S, Wang Z, Shi M, Zhao X, Yuan J, Li J, Yang X, Bin E, Wei D, Zhang H, Zhang J, Yang C, Cai T, Dai H, Chen J, Tang N. Wu H, et al. Cell. 2020 Jan 9;180(1):107-121.e17. doi: 10.1016/j.cell.2019.11.027. Epub 2019 Dec 19. Cell. 2020. PMID: 31866069
Fibrosis can develop in most organs and causes organ failure. The most common type of lung fibrosis is known as idiopathic pulmonary fibrosis, in which fibrosis starts at the lung periphery and then progresses toward the lung center, even
Fibrosis can develop in most organs and causes organ failure. The most common type of lung fibrosis is known as idiopathic
IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity.
Yang L, Herrera J, Gilbertsen A, Xia H, Smith K, Benyumov A, Bitterman PB, Henke CA. Yang L, et al. Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L127-L136. doi: 10.1152/ajplung.00200.2017. Epub 2017 Aug 31. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 28860143 Free PMC article.
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the mechanisms driving progression remain incompletely defined. We previously reported that the IPF lung harbors fibrogenic mesenchymal progenitor cells (MPCs), which serve
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the mechanisms driving progression rema
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