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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1990 1
2000 1
2001 2
2002 1
2003 1
2004 3
2005 3
2006 8
2007 6
2008 14
2009 6
2010 14
2011 25
2012 24
2013 31
2014 50
2015 31
2016 32
2017 43
2018 43
2019 34
2020 56
2021 68
2022 53
2023 43
2024 20

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563 results

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Page 1
Health effects and known pathology associated with the use of E-cigarettes.
Esteban-Lopez M, Perry MD, Garbinski LD, Manevski M, Andre M, Ceyhan Y, Caobi A, Paul P, Lau LS, Ramelow J, Owens F, Souchak J, Ales E, El-Hage N. Esteban-Lopez M, et al. Toxicol Rep. 2022 Jun 16;9:1357-1368. doi: 10.1016/j.toxrep.2022.06.006. eCollection 2022. Toxicol Rep. 2022. PMID: 36561957 Free PMC article. Review.
Different components of e-cigarettes, including food-safe liquid solvents and flavorings, can cause health issues related to pneumonia, pulmonary injury, and bronchiolitis. In addition, e-cigarettes contain alarmingly high levels of carcinogens and toxicants that may have …
Different components of e-cigarettes, including food-safe liquid solvents and flavorings, can cause health issues related to pneumonia, p
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
How LTbetaR signalling drives chronic tissue damage particularly in the lung, the mechanism(s) that regulate this process, and whether LTbetaR blockade might be of therapeutic value have remained unclear. Here we demonstrate increased expression of LTbetaR ligands in adapt …
How LTbetaR signalling drives chronic tissue damage particularly in the lung, the mechanism(s) that regulate this process, and whethe …
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
The human lung differs substantially from its mouse counterpart, resulting in a distinct distal airway architecture affected by disease pathology in chronic obstructive pulmonary disease. In humans, the distal branches of the airway interweave w …
The human lung differs substantially from its mouse counterpart, resulting in a distinct distal airway architecture affected by disease
Alpha-1 antitrypsin deficiency: outstanding questions and future directions.
Torres-Durán M, Lopez-Campos JL, Barrecheguren M, Miravitlles M, Martinez-Delgado B, Castillo S, Escribano A, Baloira A, Navarro-Garcia MM, Pellicer D, Bañuls L, Magallón M, Casas F, Dasí F. Torres-Durán M, et al. Orphanet J Rare Dis. 2018 Jul 11;13(1):114. doi: 10.1186/s13023-018-0856-9. Orphanet J Rare Dis. 2018. PMID: 29996870 Free PMC article. Review.
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is a rare hereditary condition that leads to decreased circulating alpha-1 antitrypsin (AAT) levels, significantly increasing the risk of serious lung and/or liver disease in children and adults, in which some aspects remai …
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is a rare hereditary condition that leads to decreased circulating alpha-1 antitrypsin (AA …
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Rao W, et al. Cell. 2020 May 14;181(4):848-864.e18. doi: 10.1016/j.cell.2020.03.047. Epub 2020 Apr 15. Cell. 2020. PMID: 32298651 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic bronchitis, small airway obstruction, and emphysema that represents a leading cause of death worldwide. ...Here we apply single-cell cloning technologies t
Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic bronchitis, sma
Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis.
Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, Engelhardt JF, Dickey BF, Parekh KR, McKeon FD, Xian W. Wang S, et al. Sci Transl Med. 2023 Apr 26;15(693):eabp9528. doi: 10.1126/scitranslmed.abp9528. Epub 2023 Apr 26. Sci Transl Med. 2023. PMID: 37099633 Free PMC article.
We used single-cell cloning technologies to generate "libraries" of basal stem cells from the distal lungs of 16 patients with IPF and 10 controls. ...Drug screens highlighted specific vulnerabilities of this profibrotic variant to inhibitors of epidermal growth fac …
We used single-cell cloning technologies to generate "libraries" of basal stem cells from the distal lungs of 16 patients with …
Natural products, PGC-1 α , and Duchenne muscular dystrophy.
Suntar I, Sureda A, Belwal T, Sanches Silva A, Vacca RA, Tewari D, Sobarzo-Sánchez E, Nabavi SF, Shirooie S, Dehpour AR, Xu S, Yousefi B, Majidinia M, Daglia M, D'Antona G, Nabavi SM. Suntar I, et al. Acta Pharm Sin B. 2020 May;10(5):734-745. doi: 10.1016/j.apsb.2020.01.001. Epub 2020 Jan 8. Acta Pharm Sin B. 2020. PMID: 32528825 Free PMC article. Review.
Recent advances in lung organoid development and applications in disease modeling.
Vazquez-Armendariz AI, Tata PR. Vazquez-Armendariz AI, et al. J Clin Invest. 2023 Nov 15;133(22):e170500. doi: 10.1172/JCI170500. J Clin Invest. 2023. PMID: 37966116 Free PMC article. Review.
Advanced lung organoid platforms derived from various sources, including adult, fetal, and induced pluripotent stem cells, have now been generated, which more closely mimic the cellular architecture found within the airways and alveoli. ...Thus, these developments i …
Advanced lung organoid platforms derived from various sources, including adult, fetal, and induced pluripotent stem cells, hav …
Reversal of emphysema by restoration of pulmonary endothelial cells.
Hisata S, Racanelli AC, Kermani P, Schreiner R, Houghton S, Palikuqi B, Kunar B, Zhou A, McConn K, Capili A, Redmond D, Nolan DJ, Ginsberg M, Ding BS, Martinez FJ, Scandura JM, Cloonan SM, Rafii S, Choi AMK. Hisata S, et al. J Exp Med. 2021 Aug 2;218(8):e20200938. doi: 10.1084/jem.20200938. Epub 2021 Jul 21. J Exp Med. 2021. PMID: 34287647 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is marked by airway inflammation and airspace enlargement (emphysema) leading to airflow obstruction and eventual respiratory failure. ...Here, we show the centrality of endothelial cells to th
Chronic obstructive pulmonary disease (COPD) is marked by airway inflammation and airspace enlargement (e
563 results