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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1990 1
2000 1
2001 2
2002 1
2003 1
2004 3
2005 3
2006 8
2007 6
2008 14
2009 6
2010 14
2011 24
2012 24
2013 31
2014 50
2015 31
2016 32
2017 43
2018 43
2019 34
2020 56
2021 68
2022 25
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477 results
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Page 1
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
How LTbetaR signalling drives chronic tissue damage particularly in the lung, the mechanism(s) that regulate this process, and whether LTbetaR blockade might be of therapeutic value have remained unclear. Here we demonstrate increased expression of LTbetaR ligands in adapt …
How LTbetaR signalling drives chronic tissue damage particularly in the lung, the mechanism(s) that regulate this process, and whethe …
Update in Chronic Obstructive Pulmonary Disease 2019.
Alter P, Baker JR, Dauletbaev N, Donnelly LE, Pistenmaa C, Schmeck B, Washko G, Vogelmeier CF. Alter P, et al. Am J Respir Crit Care Med. 2020 Aug 1;202(3):348-355. doi: 10.1164/rccm.202002-0370UP. Am J Respir Crit Care Med. 2020. PMID: 32407642 Review. No abstract available.
Alpha-1 antitrypsin deficiency: outstanding questions and future directions.
Torres-Durán M, Lopez-Campos JL, Barrecheguren M, Miravitlles M, Martinez-Delgado B, Castillo S, Escribano A, Baloira A, Navarro-Garcia MM, Pellicer D, Bañuls L, Magallón M, Casas F, Dasí F. Torres-Durán M, et al. Orphanet J Rare Dis. 2018 Jul 11;13(1):114. doi: 10.1186/s13023-018-0856-9. Orphanet J Rare Dis. 2018. PMID: 29996870 Free PMC article. Review.
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is a rare hereditary condition that leads to decreased circulating alpha-1 antitrypsin (AAT) levels, significantly increasing the risk of serious lung and/or liver disease in children and adults, in which some aspects remai …
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is a rare hereditary condition that leads to decreased circulating alpha-1 antitrypsin (AA …
Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases.
Ha H, Debnath B, Neamati N. Ha H, et al. Theranostics. 2017 Apr 7;7(6):1543-1588. doi: 10.7150/thno.15625. eCollection 2017. Theranostics. 2017. PMID: 28529637 Free PMC article. Review.
The CXCL8-CXCR1/2 signaling axis is involved in the pathogenesis of several diseases including chronic obstructive pulmonary diseases (COPD), asthma, cystic fibrosis and cancer. ...Currently, several of these inhibitors are in advanced clinical trials …
The CXCL8-CXCR1/2 signaling axis is involved in the pathogenesis of several diseases including chronic obstructive pulmonar
Epithelial repair mechanisms in the lung.
Crosby LM, Waters CM. Crosby LM, et al. Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L715-31. doi: 10.1152/ajplung.00361.2009. Epub 2010 Apr 2. Am J Physiol Lung Cell Mol Physiol. 2010. PMID: 20363851 Free PMC article. Review.
Changes in mechanical forces may also affect these pathways. Both localized and distal progenitor stem cells are recruited into the injured area, and proliferation and phenotypic differentiation of these cells leads to recovery of epithelial function. Persist …
Changes in mechanical forces may also affect these pathways. Both localized and distal progenitor stem cells are recruited int …
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Rao W, et al. Cell. 2020 May 14;181(4):848-864.e18. doi: 10.1016/j.cell.2020.03.047. Epub 2020 Apr 15. Cell. 2020. PMID: 32298651 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic bronchitis, small airway obstruction, and emphysema that represents a leading cause of death worldwide. ...Here we apply single-cell cloning technologies t
Chronic obstructive pulmonary disease (COPD) is a progressive condition of chronic bronchitis, sma
Bronchioalveolar stem cells in lung repair, regeneration and disease.
Jones-Freeman B, Starkey MR. Jones-Freeman B, et al. J Pathol. 2020 Nov;252(3):219-226. doi: 10.1002/path.5527. Epub 2020 Oct 1. J Pathol. 2020. PMID: 32737996 Review.
Bronchioalveolar stem cells (BASCs) are a lung resident stem cell population located at bronchioalveolar duct junctions that contribute to the maintenance of bronchiolar club cells and alveolar epithelial cells of the distal lung. ...These novel …
Bronchioalveolar stem cells (BASCs) are a lung resident stem cell population located at bronchioalveolar duct junctions …
The potential of mesenchymal stem cell therapy for chronic lung disease.
Cruz FF, Rocco PRM. Cruz FF, et al. Expert Rev Respir Med. 2020 Jan;14(1):31-39. doi: 10.1080/17476348.2020.1679628. Epub 2019 Oct 15. Expert Rev Respir Med. 2020. PMID: 31608724 Review.
Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung function and survival in chronic inflammatory lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), idiopathic p
Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung function and survival in chronic in …
Present and Future of Bronchopulmonary Dysplasia.
Bonadies L, Zaramella P, Porzionato A, Perilongo G, Muraca M, Baraldi E. Bonadies L, et al. J Clin Med. 2020 May 20;9(5):1539. doi: 10.3390/jcm9051539. J Clin Med. 2020. PMID: 32443685 Free PMC article. Review.
Seeing that BPD appears to have a role in the early origin of chronic obstructive pulmonary disease, its prevention is pivotal also in long-term respiratory outcome of these patients. ...Mesenchymal stromal/stem cells (MSCs) have revealed …
Seeing that BPD appears to have a role in the early origin of chronic obstructive pulmonary disease, its prevent …
Extracellular vesicles: novel communicators in lung diseases.
Mohan A, Agarwal S, Clauss M, Britt NS, Dhillon NK. Mohan A, et al. Respir Res. 2020 Jul 8;21(1):175. doi: 10.1186/s12931-020-01423-y. Respir Res. 2020. PMID: 32641036 Free PMC article. Review.
In addition to the endothelium, EVs may arise from alveolar macrophages, fibroblasts and epithelial cells. Because EVs harbor cargo molecules, such as miRNA, mRNA, and proteins, these intercellular communicators provide important insight into the health and disease
In addition to the endothelium, EVs may arise from alveolar macrophages, fibroblasts and epithelial cells. Because EVs harbor cargo m …
477 results