Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous genotype for MTHFR treated with 5-fluorouracil-based adjuvant chemotherapy

Chemotherapy. 2004 Oct;50(4):194-5. doi: 10.1159/000081031. Epub 2004 Sep 23.

Authors

Gaia Schiavon¹, Bruno Vincenzi, Daniele Santini, Giuseppe Avvisati, Giuseppe Tonini

Affiliation

¹ Medical Oncology and Haematology, Campus Bio-Medico University, Via Emilio Longoni 83, IT-00155 Rome, Italy.

PMID: 15452397
DOI: 10.1159/000081031

No abstract available

MeSH terms

Aged
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Chemotherapy, Adjuvant
Colonic Neoplasms / drug therapy*
Fluorouracil / administration & dosage
Fluorouracil / adverse effects*
Fluorouracil / metabolism
Genotype
Humans
Leucovorin / administration & dosage
Male
Methylenetetrahydrofolate Reductase (NADPH2) / genetics*
Methylenetetrahydrofolate Reductase (NADPH2) / pharmacology*
Risk Factors
Thrombophlebitis / chemically induced*
Thrombophlebitis / genetics*

Substances

Methylenetetrahydrofolate Reductase (NADPH2)
Leucovorin
Fluorouracil