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54 results

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Page 1
Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study.
van der Hulle T, Cheung WY, Kooij S, Beenen LFM, van Bemmel T, van Es J, Faber LM, Hazelaar GM, Heringhaus C, Hofstee H, Hovens MMC, Kaasjager KAH, van Klink RCJ, Kruip MJHA, Loeffen RF, Mairuhu ATA, Middeldorp S, Nijkeuter M, van der Pol LM, Schol-Gelok S, Ten Wolde M, Klok FA, Huisman MV; YEARS study group. van der Hulle T, et al. Lancet. 2017 Jul 15;390(10091):289-297. doi: 10.1016/S0140-6736(17)30885-1. Epub 2017 May 23. Lancet. 2017. PMID: 28549662 Clinical Trial.
FINDINGS: 3616 consecutive patients with clinically suspected pulmonary embolism were screened, of whom 151 (4%) were excluded. The remaining 3465 patients were assessed of whom 456 (13%) were diagnosed with pulmonary embolism at baseline. Of the 2946 …
FINDINGS: 3616 consecutive patients with clinically suspected pulmonary embolism were screened, of whom 151 (4%) were excluded …
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism.
Hokusai-VTE Investigators; Büller HR, Décousus H, Grosso MA, Mercuri M, Middeldorp S, Prins MH, Raskob GE, Schellong SM, Schwocho L, Segers A, Shi M, Verhamme P, Wells P. Hokusai-VTE Investigators, et al. N Engl J Med. 2013 Oct 10;369(15):1406-15. doi: 10.1056/NEJMoa1306638. Epub 2013 Aug 31. N Engl J Med. 2013. PMID: 23991658 Free article. Clinical Trial.
RESULTS: A total of 4921 patients presented with deep-vein thrombosis, and 3319 with a pulmonary embolism. Among patients receiving warfarin, the time in the therapeutic range was 63.5%. ...CONCLUSIONS: Edoxaban administered once daily after initial treatment …
RESULTS: A total of 4921 patients presented with deep-vein thrombosis, and 3319 with a pulmonary embolism. Among patien …
Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study.
Righini M, Van Es J, Den Exter PL, Roy PM, Verschuren F, Ghuysen A, Rutschmann OT, Sanchez O, Jaffrelot M, Trinh-Duc A, Le Gall C, Moustafa F, Principe A, Van Houten AA, Ten Wolde M, Douma RA, Hazelaar G, Erkens PM, Van Kralingen KW, Grootenboers MJ, Durian MF, Cheung YW, Meyer G, Bounameaux H, Huisman MV, Kamphuisen PW, Le Gal G. Righini M, et al. JAMA. 2014 Mar 19;311(11):1117-24. doi: 10.1001/jama.2014.2135. JAMA. 2014. PMID: 24643601 Free article.
IMPORTANCE: D-dimer measurement is an important step in the diagnostic strategy of clinically suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly patients. OBJECTIVE: To prospectively validate whether an age-adjusted D-dimer cu …
IMPORTANCE: D-dimer measurement is an important step in the diagnostic strategy of clinically suspected acute pulmonary embolism …
Acute pulmonary embolism. Part 2: treatment.
van Es J, Douma RA, Gerdes VE, Kamphuisen PW, Büller HR. van Es J, et al. Nat Rev Cardiol. 2010 Nov;7(11):613-22. doi: 10.1038/nrcardio.2010.141. Epub 2010 Sep 14. Nat Rev Cardiol. 2010. PMID: 20842179 Review.
The clinical presentation of pulmonary embolism (PE) varies widely, ranging from only limited symptoms to severe cardiogenic shock. ...By contrast, thrombolysis is a widely accepted treatment strategy for patients with hemodynamic shock (massive PE). ...
The clinical presentation of pulmonary embolism (PE) varies widely, ranging from only limited symptoms to severe cardiogenic s …
Clinical and radiologic characteristics of chronic thromboembolic pulmonary hypertension patients without a history of acute venous thromboembolism.
van Kan C, van Es J, Idrissi HE, Ruigrok D, Nossent EJ, Aman J, Klok FA, Bogaard HJ, Meijboom LJ, Vonk-Noordegraaf A. van Kan C, et al. J Thromb Haemost. 2025 Jun;23(6):1920-1926. doi: 10.1016/j.jtha.2025.02.033. Epub 2025 Mar 6. J Thromb Haemost. 2025. PMID: 40056989 Free article.
BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is thought to result from incomplete resolution of vascular obstruction following acute pulmonary embolism. However, at least 25% of patients with CTEPH do not have a documented e …
BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is thought to result from incomplete resolution of vascular …
Venous thrombosis and coagulation parameters in patients with pure venous malformations.
van Es J, Kappelhof NA, Douma RA, Meijers JCM, Gerdes VEA, van der Horst CMAM. van Es J, et al. Neth J Med. 2017 Oct;75(8):328-334. Neth J Med. 2017. PMID: 29219827 Free article.
A total of 68 patients underwent CUS. Superficial vein thrombosis was observed in 10 (15%) cases; 1 patient had a current asymptomatic deep venous thrombosis. Residual superficial or deep thrombosis was observed in 25 patients (36%). In total, 49% had either …
A total of 68 patients underwent CUS. Superficial vein thrombosis was observed in 10 (15%) cases; 1 patient had a current asymptomati …
Quality of life after pulmonary embolism as assessed with SF-36 and PEmb-QoL.
van Es J, den Exter PL, Kaptein AA, Andela CD, Erkens PM, Klok FA, Douma RA, Mos IC, Cohn DM, Kamphuisen PW, Huisman MV, Middeldorp S. van Es J, et al. Thromb Res. 2013 Nov;132(5):500-5. doi: 10.1016/j.thromres.2013.06.016. Epub 2013 Oct 3. Thromb Res. 2013. PMID: 24090607
INTRODUCTION: Although quality of life (QoL) is recognized as an important indicator of the course of a disease, it has rarely been addressed in studies evaluating the outcome of care for patients with pulmonary embolism (PE). This study primarily aimed to evaluate …
INTRODUCTION: Although quality of life (QoL) is recognized as an important indicator of the course of a disease, it has rarely been addresse …
Is a normal computed tomography pulmonary angiography safe to rule out acute pulmonary embolism in patients with a likely clinical probability? A patient-level meta-analysis.
van der Hulle T, van Es N, den Exter PL, van Es J, Mos ICM, Douma RA, Kruip MJHA, Hovens MMC, Ten Wolde M, Nijkeuter M, Ten Cate H, Kamphuisen PW, Büller HR, Huisman MV, Klok FA. van der Hulle T, et al. Thromb Haemost. 2017 Jul 26;117(8):1622-1629. doi: 10.1160/TH17-02-0076. Epub 2017 Jun 1. Thromb Haemost. 2017. PMID: 28569924
A normal computed tomography pulmonary angiography (CTPA) remains a controversial criterion for ruling out acute pulmonary embolism (PE) in patients with a likely clinical probability. We set out to determine the risk of VTE and fatal PE after a normal CTPA in this …
A normal computed tomography pulmonary angiography (CTPA) remains a controversial criterion for ruling out acute pulmonary embolis …
Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry.
Proietti M, Vitolo M, Harrison SL, Lane DA, Fauchier L, Marin F, Nabauer M, Potpara TS, Dan GA, Boriani G, Lip GYH; ESC-EHRA EORP-AF Long-Term General Registry Investigators. Proietti M, et al. BMC Med. 2021 Oct 20;19(1):256. doi: 10.1186/s12916-021-02120-3. BMC Med. 2021. PMID: 34666757 Free PMC article.
54 results