(("Brunger AT"[au] OR "Chu S"[au] OR "Feng L"[au] OR "Garcia KC"[au] OR "Goodman MB"[au] OR "Kobilka BK"[au] OR "Lewis RS"[au] OR "Madison DV"[au] OR "Maduke M"[au] OR "O’Brien LE"[au] OR "Skiniotis G"[au] OR "Südhof TC"[au] OR "Weis WI"[au]) AND ("S - Search Results

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Results by year

Year	Number of Results
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Overcoming lung cancer immunotherapy resistance by combining non-toxic variants of IL-12 and IL-2.

Horton BL, D'Souza AD, Zagorulya M, McCreery CV, Abhiraman GC, Picton LK, Sheen A, Agarwal Y, Momin N, Wittrup KD, White FM, Garcia KC, Spranger S. Horton BL, et al. Among authors: garcia kc. JCI Insight. 2023 Sep 5:e172728. doi: 10.1172/jci.insight.172728. Online ahead of print. JCI Insight. 2023. PMID: 37669107 Free article.

Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy.

Wellhausen N, O'Connell RP, Lesch S, Engel NW, Rennels AK, Gonzales D, Herbst F, Young RM, Garcia KC, Weiner D, June CH, Gill SI. Wellhausen N, et al. Among authors: garcia kc. Sci Transl Med. 2023 Sep 20;15(714):eadi1145. doi: 10.1126/scitranslmed.adi1145. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37651540

Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.

Tsutsumi N, Masoumi Z, James SC, Tucker JA, Winkelmann H, Grey W, Picton LK, Moss L, Wilson SC, Caveney NA, Jude KM, Gati C, Piehler J, Hitchcock IS, Garcia KC. Tsutsumi N, et al. Among authors: garcia kc. Cell. 2023 Sep 14;186(19):4189-4203.e22. doi: 10.1016/j.cell.2023.07.037. Epub 2023 Aug 25. Cell. 2023. PMID: 37633268 Free article.

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

Sclip A, Südhof TC. Sclip A, et al. Among authors: sudhof tc. Nat Commun. 2023 Aug 17;14(1):4976. doi: 10.1038/s41467-023-40526-0. Nat Commun. 2023. PMID: 37591863 Free PMC article.

Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer's disease.

Essayan-Perez S, Südhof TC. Essayan-Perez S, et al. Among authors: sudhof tc. Neuron. 2023 Aug 1:S0896-6273(23)00513-5. doi: 10.1016/j.neuron.2023.07.005. Online ahead of print. Neuron. 2023. PMID: 37543038 Free article.

Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism.

Caveney NA, Tsutsumi N, Garcia KC. Caveney NA, et al. Among authors: garcia kc. Elife. 2023 Aug 3;12:RP86784. doi: 10.7554/eLife.86784. Elife. 2023. PMID: 37535399 Free PMC article.

Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.

Yang A, Jude KM, Lai B, Minot M, Kocyla AM, Glassman CR, Nishimiya D, Kim YS, Reddy ST, Khan AA, Garcia KC. Yang A, et al. Among authors: garcia kc. Science. 2023 Jul 28;381(6656):eadh1720. doi: 10.1126/science.adh1720. Epub 2023 Jul 28. Science. 2023. PMID: 37499032 Free PMC article.

Structural basis of α_1A-adrenergic receptor activation and recognition by an extracellular nanobody.

Toyoda Y, Zhu A, Kong F, Shan S, Zhao J, Wang N, Sun X, Zhang L, Yan C, Kobilka BK, Liu X. Toyoda Y, et al. Among authors: kobilka bk. Nat Commun. 2023 Jun 20;14(1):3655. doi: 10.1038/s41467-023-39310-x. Nat Commun. 2023. PMID: 37339967 Free PMC article.

A structural blueprint for interleukin-21 signal modulation.

Abhiraman GC, Bruun TUJ, Caveney NA, Su LL, Saxton RA, Yin Q, Tang S, Davis MM, Jude KM, Garcia KC. Abhiraman GC, et al. Among authors: garcia kc. Cell Rep. 2023 Jun 27;42(6):112657. doi: 10.1016/j.celrep.2023.112657. Epub 2023 Jun 19. Cell Rep. 2023. PMID: 37339051 Free PMC article.

Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56.

Vizurraga AL, Robertson MJ, Yu M, Skiniotis G, Tall GG. Vizurraga AL, et al. Among authors: skiniotis g. Mol Pharmacol. 2023 Jul;104(1):28-41. doi: 10.1124/molpharm.123.000688. Epub 2023 Jun 8. Mol Pharmacol. 2023. PMID: 37290962 Free PMC article.

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