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33 results

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Page 1
Thrombolytic therapy for pulmonary embolism.
Zuo Z, Yue J, Dong BR, Wu T, Liu GJ, Hao Q. Zuo Z, et al. Cochrane Database Syst Rev. 2021 Apr 15;4(4):CD004437. doi: 10.1002/14651858.CD004437.pub6. Cochrane Database Syst Rev. 2021. PMID: 33857326 Free PMC article.
SELECTION CRITERIA: We included randomised controlled trials (RCTs) that compared thrombolytic therapy followed by heparin versus heparin alone, heparin plus placebo, or surgical intervention for people with acute PE (massive/submassive). ...AUTHORS' CONCLUSIONS: Low-certa …
SELECTION CRITERIA: We included randomised controlled trials (RCTs) that compared thrombolytic therapy followed by heparin versus hep …
Fibrinolysis for patients with intermediate-risk pulmonary embolism.
Meyer G, Vicaut E, Danays T, Agnelli G, Becattini C, Beyer-Westendorf J, Bluhmki E, Bouvaist H, Brenner B, Couturaud F, Dellas C, Empen K, Franca A, Galiè N, Geibel A, Goldhaber SZ, Jimenez D, Kozak M, Kupatt C, Kucher N, Lang IM, Lankeit M, Meneveau N, Pacouret G, Palazzini M, Petris A, Pruszczyk P, Rugolotto M, Salvi A, Schellong S, Sebbane M, Sobkowicz B, Stefanovic BS, Thiele H, Torbicki A, Verschuren F, Konstantinides SV; PEITHO Investigators. Meyer G, et al. N Engl J Med. 2014 Apr 10;370(15):1402-11. doi: 10.1056/NEJMoa1302097. N Engl J Med. 2014. PMID: 24716681 Free article. Clinical Trial.
BACKGROUND: The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS: In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin in normotensive patients with intermedi …
BACKGROUND: The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS: In a random
Reduced-Dose Intravenous Thrombolysis for Acute Intermediate-High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial.
Sanchez O, Charles-Nelson A, Ageno W, Barco S, Binder H, Chatellier G, Duerschmied D, Empen K, Ferreira M, Girard P, Huisman MV, Jiménez D, Katsahian S, Kozak M, Lankeit M, Meneveau N, Pruszczyk P, Petris A, Righini M, Rosenkranz S, Schellong S, Stefanovic B, Verhamme P, de Wit K, Vicaut E, Zirlik A, Konstantinides SV, Meyer G; PEITHO-3 Investigators. Sanchez O, et al. Thromb Haemost. 2022 May;122(5):857-866. doi: 10.1055/a-1653-4699. Epub 2021 Oct 31. Thromb Haemost. 2022. PMID: 34560806 Free PMC article. Clinical Trial.
The Pulmonary Embolism International THrOmbolysis (PEITHO)-3 study (ClinicalTrials.gov Identifier: NCT04430569) is a randomized, placebo-controlled, double-blind, multicenter, multinational trial with long-term follow-up. ...
The Pulmonary Embolism International THrOmbolysis (PEITHO)-3 study (ClinicalTrials.gov Identifier: NCT04430569) is a randomized, plac …
Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism.
Kucher N, Boekstegers P, Müller OJ, Kupatt C, Beyer-Westendorf J, Heitzer T, Tebbe U, Horstkotte J, Müller R, Blessing E, Greif M, Lange P, Hoffmann RT, Werth S, Barmeyer A, Härtel D, Grünwald H, Empen K, Baumgartner I. Kucher N, et al. Circulation. 2014 Jan 28;129(4):479-86. doi: 10.1161/CIRCULATIONAHA.113.005544. Epub 2013 Nov 13. Circulation. 2014. PMID: 24226805 Clinical Trial.
BACKGROUND: In patients with acute pulmonary embolism, systemic thrombolysis improves right ventricular (RV) dilatation, is associated with major bleeding, and is withheld in many patients at risk. This multicenter randomized, controlled trial investigated wh …
BACKGROUND: In patients with acute pulmonary embolism, systemic thrombolysis improves right ventricular (RV) dilatation, is associated with …
Thrombolytic therapy for pulmonary embolism.
Hao Q, Dong BR, Yue J, Wu T, Liu GJ. Hao Q, et al. Cochrane Database Syst Rev. 2018 Dec 18;12(12):CD004437. doi: 10.1002/14651858.CD004437.pub5. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2021 Apr 15;4:CD004437. doi: 10.1002/14651858.CD004437.pub6. PMID: 30560579 Free PMC article. Updated.
SELECTION CRITERIA: We included randomised controlled trials (RCTs) that compared thrombolytic therapy followed by heparin versus heparin alone, heparin plus placebo, or surgical intervention for patients with acute PE. ...More high-quality, blinded randomised controlle
SELECTION CRITERIA: We included randomised controlled trials (RCTs) that compared thrombolytic therapy followed by heparin versus hep …
Thrombolytic therapy for pulmonary embolism.
Hao Q, Dong BR, Yue J, Wu T, Liu GJ. Hao Q, et al. Cochrane Database Syst Rev. 2015 Sep 30;(9):CD004437. doi: 10.1002/14651858.CD004437.pub4. Cochrane Database Syst Rev. 2015. Update in: Cochrane Database Syst Rev. 2018 Dec 18;12:CD004437. doi: 10.1002/14651858.CD004437.pub5. PMID: 26419832 Updated.
SEARCH METHODS: For this update the Cochrane Vascular Group searched their Specialised Register (last searched September 2014) and the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library (last searched Issue 8, 2014). We also searched individua …
SEARCH METHODS: For this update the Cochrane Vascular Group searched their Specialised Register (last searched September 2014) and the Cochr …
Thrombolytic therapy for pulmonary embolism.
Dong BR, Hao Q, Yue J, Wu T, Liu GJ. Dong BR, et al. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD004437. doi: 10.1002/14651858.CD004437.pub3. Cochrane Database Syst Rev. 2009. Update in: Cochrane Database Syst Rev. 2015 Sep 30;(9):CD004437. doi: 10.1002/14651858.CD004437.pub4. PMID: 19588357 Updated.
SEARCH STRATEGY: For this update the Cochrane Peripheral Vascular Diseases Review Group searched their Specialised Register (last searched April 2009) and the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (last searched Issue 2, 2009). We …
SEARCH STRATEGY: For this update the Cochrane Peripheral Vascular Diseases Review Group searched their Specialised Register (last searched A …
Thrombolytic therapy for pulmonary embolism.
Dong B, Jirong Y, Liu G, Wang Q, Wu T. Dong B, et al. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD004437. doi: 10.1002/14651858.CD004437.pub2. Cochrane Database Syst Rev. 2006. Update in: Cochrane Database Syst Rev. 2009 Jul 08;(3):CD004437. doi: 10.1002/14651858.CD004437.pub3. PMID: 16625603 Updated.
We also searched individual trial collections and private databases, along with bibliographies of relevant articles. ...The most recent search was on February 6, 2006. SELECTION CRITERIA: Randomised controlled trials that compared thrombolytic therapy with placebo o …
We also searched individual trial collections and private databases, along with bibliographies of relevant articles. ...The most rece …
Effectiveness and cost effectiveness of thrombolysis in patients with acute pulmonary embolism.
Zamanian RT, Gould MK. Zamanian RT, et al. Curr Opin Pulm Med. 2008 Sep;14(5):422-6. doi: 10.1097/MCP.0b013e328307ee0f. Curr Opin Pulm Med. 2008. PMID: 18664972 Review.
Acute right ventricular dysfunction is a poor prognostic indicator in patients with pulmonary embolism. The most recent randomized controlled trial of systemic thrombolysis in patients with submassive pulmonary embolism and right ventricular dysfunction found …
Acute right ventricular dysfunction is a poor prognostic indicator in patients with pulmonary embolism. The most recent randomized
Evidence-based emergency medicine/critically appraised topic. Thrombolytic therapy for submassive pulmonary embolism?
Worster A, Smith C, Silver S, Brown MD. Worster A, et al. Ann Emerg Med. 2007 Jul;50(1):78-84. doi: 10.1016/j.annemergmed.2007.01.002. Epub 2007 Apr 20. Ann Emerg Med. 2007. PMID: 17449142 Review.
RESULTS: Two randomized trials met the inclusion criteria; one with a total of 256 patients presenting with submassive pulmonary embolism and the other trial including a subgroup of 46 patients with submassive pulmonary embolism. ...Our post hoc subgroup analysis of …
RESULTS: Two randomized trials met the inclusion criteria; one with a total of 256 patients presenting with submassive pulmonary embo …
33 results