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Page 1
Airborne transmission of influenza A/H5N1 virus between ferrets.
Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, Fouchier RA. Herfst S, et al. Science. 2012 Jun 22;336(6088):1534-41. doi: 10.1126/science.1213362. Science. 2012. PMID: 22723413 Free PMC article.
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by aerosol or respiratory droplet ("airborne transmission") between humans. ...The gene …
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not …
Airborne transmission of human-isolated avian H3N8 influenza virus between ferrets.
Sun H, Li H, Tong Q, Han Q, Liu J, Yu H, Song H, Qi J, Li J, Yang J, Lan R, Deng G, Chang H, Qu Y, Pu J, Sun Y, Lan Y, Wang D, Shi Y, Liu WJ, Chang KC, Gao GF, Liu J. Sun H, et al. Cell. 2023 Sep 14;186(19):4074-4084.e11. doi: 10.1016/j.cell.2023.08.011. Epub 2023 Sep 4. Cell. 2023. PMID: 37669665 Free article.
H3N8 avian influenza viruses (AIVs) in China caused two confirmed human infections in 2022, followed by a fatal case reported in 2023. ...Human isolates of H3N8 virus were more virulent and caused severe pathology in mice and ferrets, relative to chick …
H3N8 avian influenza viruses (AIVs) in China caused two confirmed human infections in 2022, followed by a fatal case re …
Highly pathogenic avian influenza A(H5N1) virus of clade 2.3.4.4b isolated from a human case in Chile causes fatal disease and transmits between co-housed ferrets.
Pulit-Penaloza JA, Brock N, Belser JA, Sun X, Pappas C, Kieran TJ, Basu Thakur P, Zeng H, Cui D, Frederick J, Fasce R, Tumpey TM, Maines TR. Pulit-Penaloza JA, et al. Emerg Microbes Infect. 2024 Dec;13(1):2332667. doi: 10.1080/22221751.2024.2332667. Epub 2024 Jun 13. Emerg Microbes Infect. 2024. PMID: 38494746 Free PMC article.
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses have caused large outbreaks within avian populations on five continents, with concurrent spillover into a variety of mammalian species. ...In this study, the pathogenicity and transmissibility o …
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses have caused large outbreaks within avian populations o …
Risk assessment of a highly pathogenic H5N1 influenza virus from mink.
Restori KH, Septer KM, Field CJ, Patel DR, VanInsberghe D, Raghunathan V, Lowen AC, Sutton TC. Restori KH, et al. Nat Commun. 2024 May 15;15(1):4112. doi: 10.1038/s41467-024-48475-y. Nat Commun. 2024. PMID: 38750016 Free PMC article.
To assess this threat, using the ferret model, we show an H5N1 isolate derived from mink transmits by direct contact to 75% of exposed ferrets and, in airborne transmission studies, the virus transmits to 37.5% of contacts. Sequence analyses sho …
To assess this threat, using the ferret model, we show an H5N1 isolate derived from mink transmits by direct contact to 75% of …
Characterization of a human H3N8 influenza virus.
Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, Maemura T, Pattinson D, Neumann G, Kawaoka Y. Gu C, et al. EBioMedicine. 2024 Mar;101:105034. doi: 10.1016/j.ebiom.2024.105034. Epub 2024 Feb 25. EBioMedicine. 2024. PMID: 38408394 Free PMC article.
Intranasal infection of ferrets resulted in minor weight loss and moderate fever but no mortality. ...Deep-sequencing of nasal swab samples from inoculated and exposed ferrets revealed sequence polymorphisms in the haemagglutinin protein that ma …
Intranasal infection of ferrets resulted in minor weight loss and moderate fever but no mortality. ...Deep-sequencing of nasal …
Transmission of a human isolate of clade 2.3.4.4b A(H5N1) virus in ferrets.
Pulit-Penaloza JA, Belser JA, Brock N, Kieran TJ, Sun X, Pappas C, Zeng H, Carney P, Chang J, Bradley-Ferrell B, Stevens J, De La Cruz JA, Hatta Y, Di H, Davis CT, Tumpey TM, Maines TR. Pulit-Penaloza JA, et al. Nature. 2024 Dec;636(8043):705-710. doi: 10.1038/s41586-024-08246-7. Epub 2024 Oct 28. Nature. 2024. PMID: 39467572 Free PMC article.
Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird populations with spillover into a variety of mammalian species and sporadically humans(1). ...Ferrets inoculated with TX/37 rapidly …
Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird popula …
Avian influenza A H5N1 virus: a continuous threat to humans.
To KK, Ng KH, Que TL, Chan JM, Tsang KY, Tsang AK, Chen H, Yuen KY. To KK, et al. Emerg Microbes Infect. 2012 Sep;1(9):e25. doi: 10.1038/emi.2012.24. Epub 2012 Sep 19. Emerg Microbes Infect. 2012. PMID: 26038430 Free PMC article. Review.
We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) virus subclade 2.3.2.1 and Mycoplasma pneumoniae. ...We then review the epidemiology, virology, interspecies barrier limiting poultry-to- …
We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) v …
Natural Infection with Highly Pathogenic Avian Influenza A/H5N1 Virus in Pet Ferrets.
Golke A, Jańczak D, Szaluś-Jordanow O, Dzieciątkowski T, Sapierzyński R, Moroz-Fik A, Mickiewicz M, Frymus T. Golke A, et al. Viruses. 2024 Jun 8;16(6):931. doi: 10.3390/v16060931. Viruses. 2024. PMID: 38932223 Free PMC article.
In the RT-qPCR, the throat swabs collected from all surviving ferrets as well as the samples of lungs, trachea, heart, brain, pancreas, liver, and intestine of the succumbed ferret were found positive for A/H5N1 virus RNA. To our best knowledge, this i …
In the RT-qPCR, the throat swabs collected from all surviving ferrets as well as the samples of lungs, trachea, heart, brain, pancrea …
Characterization of H5N1 avian influenza virus isolated from bird in Russia with the E627K mutation in the PB2 protein.
Marchenko VY, Panova AS, Kolosova NP, Gudymo AS, Svyatchenko SV, Danilenko AV, Vasiltsova NN, Egorova ML, Onkhonova GS, Zhestkov PD, Zinyakov NG, Andreychuk DB, Chvala IA, Kosenko MN, Moiseeva AA, Boldyrev ND, Shadrinova KN, Perfilieva ON, Ryzhikov AB. Marchenko VY, et al. Sci Rep. 2024 Nov 3;14(1):26490. doi: 10.1038/s41598-024-78175-y. Sci Rep. 2024. PMID: 39489822 Free PMC article.
Currently A(H5Nx) avian influenza viruses are globally widespread and continue to evolve. Since their emergence in 2020 novel highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b reassortant viruses have become predominant in the world and c …
Currently A(H5Nx) avian influenza viruses are globally widespread and continue to evolve. Since their emergence in 2020 novel …
The Pandemic Threat of Emerging H5 and H7 Avian Influenza Viruses.
Sutton TC. Sutton TC. Viruses. 2018 Aug 28;10(9):461. doi: 10.3390/v10090461. Viruses. 2018. PMID: 30154345 Free PMC article. Review.
Unlike more recent pandemics, most of the 1918 H1N1 virus' genome was derived directly from an avian influenza virus. Recent avian-origin H5 A/goose/Guangdong/1/1996 (GsGd) and Asian H7N9 viruses have caused several hundred human infections with high mortalit …
Unlike more recent pandemics, most of the 1918 H1N1 virus' genome was derived directly from an avian influenza virus. Recent a …
131 results