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2019 1
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Page 1
What is allosteric regulation? Exploring the exceptions that prove the rule!
McCullagh M, Zeczycki TN, Kariyawasam CS, Durie CL, Halkidis K, Fitzkee NC, Holt JM, Fenton AW. McCullagh M, et al. Among authors: fenton aw. J Biol Chem. 2024 Jan 23:105672. doi: 10.1016/j.jbc.2024.105672. Online ahead of print. J Biol Chem. 2024. PMID: 38272229 Free article. Review.
Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1.
Schaich MA, Weaver TM, Roginskaya V, Freudenthal BD, Van Houten B. Schaich MA, et al. Among authors: freudenthal bd. DNA Repair (Amst). 2024 Feb;134:103625. doi: 10.1016/j.dnarep.2024.103625. Epub 2024 Jan 17. DNA Repair (Amst). 2024. PMID: 38237481
Purified GFP-OGG1 engaged undamaged DNA for a weighted average lifetime of 5.7 s and 21% of these events underwent DNA diffusion after binding. ...In contrast, GFP-OGG1 binding dynamics on DNA substrates containing oxidative damage were relatively similar in all three cond …
Purified GFP-OGG1 engaged undamaged DNA for a weighted average lifetime of 5.7 s and 21% of these events underwent DNA diffusion afte …
O-GlcNAc regulates the mitochondrial integrated stress response by regulating ATF4.
Alghusen IM, Carman MS, Wilkins H, Ephrame SJ, Qiang A, Dias WB, Fedosyuk H, Denson AR, Swerdlow RH, Slawson C. Alghusen IM, et al. Among authors: slawson c. Front Aging Neurosci. 2023 Dec 18;15:1326127. doi: 10.3389/fnagi.2023.1326127. eCollection 2023. Front Aging Neurosci. 2023. PMID: 38192280 Free PMC article.
BACKGROUND: Accumulation of mitochondrial dysfunctional is a hallmark of age-related neurodegeneration including Alzheimer's disease (AD). Impairment of mitochondrial quality control mechanisms leading to the accumulation of damaged mitochondria and increasing neuronal str …
BACKGROUND: Accumulation of mitochondrial dysfunctional is a hallmark of age-related neurodegeneration including Alzheimer's disease …
Fructose-1-kinase has pleiotropic roles in Escherichia coli.
Weeramange C, Menjivar C, O'Neil PT, El Qaidi S, Harrison KS, Meinhardt S, Bird CL, Sreenivasan S, Hardwidge PR, Fenton AW, Hefty PS, Bose JL, Swint-Kruse L. Weeramange C, et al. Among authors: swint kruse l, fenton aw. bioRxiv. 2023 Dec 14:2023.12.14.571569. doi: 10.1101/2023.12.14.571569. Preprint. bioRxiv. 2023. PMID: 38168282 Free PMC article.
The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?
Sreenivasan S, Heffren P, Suh KS, Rodnin MV, Kosa E, Fenton AW, Ladokhin AS, Smith PE, Fontes JD, Swint-Kruse L. Sreenivasan S, et al. Among authors: fontes jd, ladokhin as, swint kruse l, fenton aw. Protein Sci. 2024 Feb;33(2):e4863. doi: 10.1002/pro.4863. Protein Sci. 2024. PMID: 38073129
In this study, we tested tuneability in the AD of full-length human class II transactivator (CIITA). Sequence analyses and experiments showed that CIITA's AD is an IDR. Functional assays of singly-substituted AD variants showed that CIITA's function was highly tunea …
In this study, we tested tuneability in the AD of full-length human class II transactivator (CIITA). Sequence analyses and experiments showe …
The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b5 core to form a helical motif that is of ancient origin.
Benson DR, Deng B, Kashipathy MM, Lovell S, Battaile KP, Cooper A, Gao P, Fenton AW, Zhu H. Benson DR, et al. Among authors: fenton aw. Proteins. 2023 Dec 1. doi: 10.1002/prot.26647. Online ahead of print. Proteins. 2023. PMID: 38041394
Ncb5or also contains an N-terminal intrinsically disordered region of 50 residues that has no homologs in other protein families in animals but features a distinctive, conserved L(34) MDWIRL(40) motif also present in reduced lateral root formation (RLF) protein in rice and increa …
Ncb5or also contains an N-terminal intrinsically disordered region of 50 residues that has no homologs in other protein families in animals …
Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glycosylase 1.
Schaich MA, Weaver TM, Roginskaya V, Freudenthal BD, Van Houten B. Schaich MA, et al. Among authors: freudenthal bd. bioRxiv. 2023 Nov 2:2023.11.01.565178. doi: 10.1101/2023.11.01.565178. Preprint. bioRxiv. 2023. PMID: 37961208 Free PMC article. Updated.
Purified GFP-OGG1 engaged undamaged DNA for a weighted average lifetime of 5.7 s and 21% of these events underwent DNA diffusion after binding. ...In contrast, GFP-OGG1 binding dynamics on DNA substrates containing oxidative damage were relatively similar in all three cond …
Purified GFP-OGG1 engaged undamaged DNA for a weighted average lifetime of 5.7 s and 21% of these events underwent DNA diffusion afte …
The essential role of O-GlcNAcylation in hepatic differentiation.
Robarts DR, Kotulkar M, Paine-Cabrera D, Venneman KK, Hanover JA, Zachara NE, Slawson C, Apte U. Robarts DR, et al. Among authors: slawson c. Hepatol Commun. 2023 Nov 6;7(11):e0283. doi: 10.1097/HC9.0000000000000283. eCollection 2023 Nov 1. Hepatol Commun. 2023. PMID: 37930118 Free PMC article.
106 results