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Year Number of Results
2002 9
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2009 17
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2011 13
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2015 20
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334 results

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Page 1
Editorial: Inflammation and lipid signaling in disease pathogenesis.
Patrignani P, Brüne B, Sala A, Minuz P, Steinhilber D. Patrignani P, et al. Among authors: brune b. Front Pharmacol. 2025 May 16;16:1623707. doi: 10.3389/fphar.2025.1623707. eCollection 2025. Front Pharmacol. 2025. PMID: 40453658 Free PMC article. No abstract available.
S1PR4-dependent effects of Etrasimod on primary human myeloid immune cell activation.
Sailer FK, Palmer MA, Aliraj B, Heering J, Brockmann A, Elewa MAF, Röhrig A, Proschak E, Stepniak DT, Ramsey S, Brüne B, Weigert A. Sailer FK, et al. Among authors: brune b. Front Pharmacol. 2025 Apr 24;16:1590816. doi: 10.3389/fphar.2025.1590816. eCollection 2025. Front Pharmacol. 2025. PMID: 40342995 Free PMC article.
Chronic autoinflammatory diseases such as the inflammatory bowel diseases (IBDs) Crohn's disease and ulcerative colitis are characterized by an abundance of disease-propagating immune cells in the gastrointestinal tract. ...
Chronic autoinflammatory diseases such as the inflammatory bowel diseases (IBDs) Crohn's disease and ulcerative colitis are character …
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling.
Palmer MA, Kirchhoff R, Buerger C, Benatzy Y, Schebb NH, Brüne B. Palmer MA, et al. Among authors: brune b. Cell Death Dis. 2025 Jan 22;16(1):39. doi: 10.1038/s41419-025-07357-x. Cell Death Dis. 2025. PMID: 39843435 Free PMC article.
Arachidonate 15-lipoxygenase type B (ALOX15B) peroxidises polyunsaturated fatty acids to their corresponding fatty acid hydroperoxides, which are subsequently reduced into hydroxy-fatty acids. ...
Arachidonate 15-lipoxygenase type B (ALOX15B) peroxidises polyunsaturated fatty acids to their corresponding fatty acid hydroperoxide …
Inflammation in a ferroptotic environment.
Wickert A, Schwantes A, Fuhrmann DC, Brüne B. Wickert A, et al. Among authors: brune b. Front Pharmacol. 2024 Sep 20;15:1474285. doi: 10.3389/fphar.2024.1474285. eCollection 2024. Front Pharmacol. 2024. PMID: 39372215 Free PMC article. Review.
Activation of inflammatory pathways such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) and hypoxia inducible factors (HIFs) are known to alter the ability of cells to undergo ferroptosis and are closely connected to iron metabolism. ...
Activation of inflammatory pathways such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) and hypoxia in …
Ferroptosis in health and disease.
Berndt C, Alborzinia H, Amen VS, Ayton S, Barayeu U, Bartelt A, Bayir H, Bebber CM, Birsoy K, Böttcher JP, Brabletz S, Brabletz T, Brown AR, Brüne B, Bulli G, Bruneau A, Chen Q, DeNicola GM, Dick TP, Distéfano A, Dixon SJ, Engler JB, Esser-von Bieren J, Fedorova M, Friedmann Angeli JP, Friese MA, Fuhrmann DC, García-Sáez AJ, Garbowicz K, Götz M, Gu W, Hammerich L, Hassannia B, Jiang X, Jeridi A, Kang YP, Kagan VE, Konrad DB, Kotschi S, Lei P, Le Tertre M, Lev S, Liang D, Linkermann A, Lohr C, Lorenz S, Luedde T, Methner A, Michalke B, Milton AV, Min J, Mishima E, Müller S, Motohashi H, Muckenthaler MU, Murakami S, Olzmann JA, Pagnussat G, Pan Z, Papagiannakopoulos T, Pedrera Puentes L, Pratt DA, Proneth B, Ramsauer L, Rodriguez R, Saito Y, Schmidt F, Schmitt C, Schulze A, Schwab A, Schwantes A, Soula M, Spitzlberger B, Stockwell BR, Thewes L, Thorn-Seshold O, Toyokuni S, Tonnus W, Trumpp A, Vandenabeele P, Vanden Berghe T, Venkataramani V, Vogel FCE, von Karstedt S, Wang F, Westermann F, Wientjens C, Wilhelm C, Wölk M, Wu K, Yang X, Yu F, Zou Y, Conrad M. Berndt C, et al. Among authors: brune b. Redox Biol. 2024 Sep;75:103211. doi: 10.1016/j.redox.2024.103211. Epub 2024 May 30. Redox Biol. 2024. PMID: 38908072 Free PMC article. Review.
Specific topics include: basic mechanisms, in vivo relevance, specialized methodologies, chemical and pharmacological tools, and the potential contribution of ferroptosis to disease etiopathology and progression. We hope that this article will not only provide established …
Specific topics include: basic mechanisms, in vivo relevance, specialized methodologies, chemical and pharmacological tools, and the potenti …
Murine Alox8 versus the human ALOX15B ortholog: differences and similarities.
Palmer MA, Benatzy Y, Brüne B. Palmer MA, et al. Among authors: brune b. Pflugers Arch. 2024 Dec;476(12):1817-1832. doi: 10.1007/s00424-024-02961-w. Epub 2024 Apr 19. Pflugers Arch. 2024. PMID: 38637408 Free PMC article. Review.
Human arachidonate 15-lipoxygenase type B is a lipoxygenase that catalyzes the peroxidation of arachidonic acid at carbon-15. ...
Human arachidonate 15-lipoxygenase type B is a lipoxygenase that catalyzes the peroxidation of arachidonic acid at carbon-15. ...
ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.
Benatzy Y, Palmer MA, Lütjohann D, Ohno RI, Kampschulte N, Schebb NH, Fuhrmann DC, Snodgrass RG, Brüne B. Benatzy Y, et al. Among authors: brune b. Redox Biol. 2024 Jun;72:103149. doi: 10.1016/j.redox.2024.103149. Epub 2024 Apr 3. Redox Biol. 2024. PMID: 38581859 Free PMC article.
Macrophage cholesterol homeostasis is crucial for health and disease and has been linked to the lipid-peroxidizing enzyme arachidonate 15-lipoxygenase type B (ALOX15B), albeit molecular mechanisms remain obscure. ...
Macrophage cholesterol homeostasis is crucial for health and disease and has been linked to the lipid-peroxidizing enzyme arachidonat …
334 results