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Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer.
Puthanmadhom Narayanan S, Wedn AM, Shah OS, Chen J, Brown DD, McAuliffe PF, Oesterreich S, Lee AV. Puthanmadhom Narayanan S, et al. Among authors: mcauliffe pf. Breast Cancer Res. 2024 Oct 30;26(1):149. doi: 10.1186/s13058-024-01900-y. Breast Cancer Res. 2024. PMID: 39478577 Free PMC article.
OBJECTIVE: Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological and molecular hallmarks that differentiate it from the more common invasive carcinoma-no special type (NST). Desp …
OBJECTIVE: Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinico …
Is the Number or Proximity of Margins Less than 2 mm Associated with an Increased Mastectomy Rate in Patients Attempting Breast Conservation Therapy for Ductal Carcinoma In Situ?
Elmore LR, Bayley EM, Clark BZ, McAuliffe PF, Cowher MS. Elmore LR, et al. Among authors: mcauliffe pf. Ann Surg Oncol. 2024 Oct;31(11):7609-7618. doi: 10.1245/s10434-024-15794-9. Epub 2024 Jul 31. Ann Surg Oncol. 2024. PMID: 39085550
BACKGROUND: Consensus guidelines recommend 2 mm margins in patients undergoing partial mastectomy (PM) for ductal carcinoma in situ (DCIS). It is unknown whether the number or proximity of margins less than 2 mm is associated with an increased mastectomy rate in patients …
BACKGROUND: Consensus guidelines recommend 2 mm margins in patients undergoing partial mastectomy (PM) for ductal carcinoma in situ …
Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
Shah OS, Nasrazadani A, Foldi J, Atkinson JM, Kleer CG, McAuliffe PF, Johnston TJ, Stallaert W, da Silva EM, Selenica P, Dopeso H, Pareja F, Mandelker D, Weigelt B, Reis-Filho JS, Bhargava R, Lucas PC, Lee AV, Oesterreich S. Shah OS, et al. Among authors: mcauliffe pf. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2322068121. doi: 10.1073/pnas.2322068121. Epub 2024 Jul 23. Proc Natl Acad Sci U S A. 2024. PMID: 39042692 Free PMC article.
Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadherin positive ductal and E-cadherin negative lobular morphologies within the same tumor, posing challenges with regard to anticipated …
Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadh …
Spatial molecular profiling of mixed invasive ductal-lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
Shah OS, Nasrazadani A, Foldi J, Atkinson JM, Kleer CG, McAuliffe PF, Johnston TJ, Stallaert W, da Silva EM, Selenica P, Dopeso H, Pareja F, Mandelker D, Weigelt B, Reis-Filho JS, Bhargava R, Lucas PC, Lee AV, Oesterreich S. Shah OS, et al. Among authors: mcauliffe pf. bioRxiv [Preprint]. 2024 Jun 16:2023.09.09.557013. doi: 10.1101/2023.09.09.557013. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2322068121. doi: 10.1073/pnas.2322068121. PMID: 38915645 Free PMC article. Updated. Preprint.
Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadherin positive ductal and E-cadherin negative lobular morphologies within the same tumor, posing challenges with regard to anticipated …
Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadh …
Upgrade Rates of Variant Lobular Carcinoma In Situ Compared to Classic Lobular Carcinoma In Situ Diagnosed in Core Needle Biopsies: A 10-Year Single Institution Retrospective Study.
Harinath L, Villatoro TM, Clark BZ, Fine JL, Yu J, Carter GJ, Diego E, McAuliffe PF, Mai P, Lu A, Zuley M, Berg WA, Bhargava R. Harinath L, et al. Among authors: mcauliffe pf. Mod Pathol. 2024 Apr;37(4):100462. doi: 10.1016/j.modpat.2024.100462. Epub 2024 Feb 28. Mod Pathol. 2024. PMID: 38428736 Free article.
The primary aim of this study was to determine the upgrade rates of variant lobular carcinoma in situ (V-LCIS, ie, combined florid [F-LCIS] and pleomorphic [P-LCIS]) compared with classic LCIS (C-LCIS) when diagnosed on core needle biopsy (CNB). ...With an average f …
The primary aim of this study was to determine the upgrade rates of variant lobular carcinoma in situ (V-LCIS, ie, combined fl …
WCRC-25: A novel luminal Invasive Lobular Carcinoma cell line model.
Elangovan A, Bossart EA, Basudan A, Tasdemir N, Shah OS, Ding K, Meier C, Heim T, Neumann C, Attaran S, Brown L, Hooda J, Miller L, Liu T, Puhalla SL, Gurda G, Lucas PC, McAuliffe PF, Atkinson JM, Lee AV, Oesterreich S. Elangovan A, et al. Among authors: mcauliffe pf. bioRxiv [Preprint]. 2023 Sep 17:2023.09.15.558023. doi: 10.1101/2023.09.15.558023. bioRxiv. 2023. PMID: 37745587 Free PMC article. Preprint.
Breast cancer is categorized by the molecular and histologic presentation of the tumor, with the major histologic subtypes being No Special Type (NST) and Invasive Lobular Carcinoma (ILC). ILC are characterized by growth in a single file discohe …
Breast cancer is categorized by the molecular and histologic presentation of the tumor, with the major histologic subtypes being No Special …
Publisher Correction: Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment.
Onkar S, Cui J, Zou J, Cardello C, Cillo AR, Uddin MR, Sagan A, Joy M, Osmanbeyoglu HU, Pogue-Geile KL, McAuliffe PF, Lucas PC, Tseng GC, Lee AV, Bruno TC, Oesterreich S, Vignali DAA. Onkar S, et al. Among authors: mcauliffe pf. Nat Cancer. 2023 Apr;4(4):582. doi: 10.1038/s43018-023-00549-4. Nat Cancer. 2023. PMID: 37012402 No abstract available.
Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment.
Onkar S, Cui J, Zou J, Cardello C, Cillo AR, Uddin MR, Sagan A, Joy M, Osmanbeyoglu HU, Pogue-Geile KL, McAuliffe PF, Lucas PC, Tseng GC, Lee AV, Bruno TC, Oesterreich S, Vignali DAA. Onkar S, et al. Among authors: mcauliffe pf. Nat Cancer. 2023 Apr;4(4):516-534. doi: 10.1038/s43018-023-00527-w. Epub 2023 Mar 16. Nat Cancer. 2023. PMID: 36927792 Free PMC article.
Despite accounting for 70% of all breast cancers, relatively little is known about the immunobiology of ER(+) breast cancer in women with invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC). To investigate this, we perfor …
Despite accounting for 70% of all breast cancers, relatively little is known about the immunobiology of ER(+) breast cancer in women with …
Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma.
Nasrazadani A, Li Y, Fang Y, Shah O, Atkinson JM, Lee JS, McAuliffe PF, Bhargava R, Tseng G, Lee AV, Lucas PC, Oesterreich S, Wolmark N. Nasrazadani A, et al. Among authors: mcauliffe pf. Br J Cancer. 2023 Apr;128(6):1030-1039. doi: 10.1038/s41416-022-02131-8. Epub 2023 Jan 5. Br J Cancer. 2023. PMID: 36604587 Free PMC article.
BACKGROUND: Mixed invasive ductal lobular carcinoma (mDLC) remains a poorly understood subtype of breast cancer composed of coexisting ductal and lobular components. METHODS: We sought to describe clinicopathologic characteristics and determine whether …
BACKGROUND: Mixed invasive ductal lobular carcinoma (mDLC) remains a poorly understood subtype of breast cancer compose …
Improving well-being for individuals with persistent pain after surgery for breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ: A randomized clinical trial.
Stalls JM, Bovbjerg DH, Somers TJ, Plumb Vilardaga JC, Kimmick GG, McAuliffe PF, Keefe FJ, Posluszny DM, Sullivan MJL, Erkanli A, Reed SD, Sutton L, Owen L, Massa L, Shelby RA. Stalls JM, et al. Among authors: mcauliffe pf. Contemp Clin Trials. 2022 Nov;122:106934. doi: 10.1016/j.cct.2022.106934. Epub 2022 Sep 21. Contemp Clin Trials. 2022. PMID: 36152791 Free PMC article. Clinical Trial.
>276,000 Americans will be diagnosed with invasive breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ this year and most will undergo breast surgery as part of their care. ...
>276,000 Americans will be diagnosed with invasive breast cancer, lobular carcinoma in situ, or ductal carcinoma …
19 results