Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1959 1
1960 1
1961 1
1963 1
1964 4
1965 1
1968 3
1969 1
1970 3
1971 2
1972 2
1973 4
1974 3
1975 3
1976 4
1977 2
1978 2
1979 3
1980 7
1981 3
1982 10
1983 11
1984 6
1985 13
1986 12
1987 13
1988 14
1989 23
1990 18
1991 12
1992 18
1993 21
1994 13
1995 10
1996 13
1997 12
1998 8
1999 9
2000 11
2001 6
2002 13
2003 13
2004 14
2005 14
2006 21
2007 19
2008 30
2009 36
2010 32
2011 35
2012 30
2013 33
2014 45
2015 41
2016 43
2017 37
2018 57
2019 37
2020 66
2021 58
2022 40
2023 44
2024 66
2025 63
2026 19

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

59 results

Results by year

Filters applied: in the last 1 year. Clear all
Page 1
A fungal-derived adjuvant amplifies the antitumoral potency of Bacillus Calmette-Guérin via reprogramming granulopoiesis.
Jurado LF, Daman AW, Li Z, Ross VMS, Nikolaou K, Tran KA, Loutochin O, McPherson VA, Prével R, Tarancón R, Couto K, Pernet E, Khan N, Cheong JG, Ramaiah R, Ketavarapu M, Kaufmann E, Glickman MS, Thanabalasuriar A, Josefowicz SZ, Divangahi M. Jurado LF, et al. Immunity. 2025 Aug 12;58(8):1984-2001.e6. doi: 10.1016/j.immuni.2025.05.026. Epub 2025 Jun 23. Immunity. 2025. PMID: 40555239
Using a preclinical orthotopic bladder cancer model, we found that a single intravesical dose of combined BCG and beta-glucan immunotherapy eradicated aggressive tumors, resulting in 100% survival. ...The tumor microenvironment can convert neutrophils into protumor …
Using a preclinical orthotopic bladder cancer model, we found that a single intravesical dose of combined BCG and beta-glucan …
Fungal beta-Glucans: Biological Properties, Immunomodulatory Effects, Diagnostic and Therapeutic Applications.
Amirinia F, Jabrodini A, Morovati H, Ardi P, Motamedi M. Amirinia F, et al. Infect Dis Clin Microbiol. 2025 Mar 27;7(1):1-16. doi: 10.36519/idcm.2025.448. eCollection 2025 Mar. Infect Dis Clin Microbiol. 2025. PMID: 40225707 Free PMC article. Review.
As a result, they help lower the risk of conditions such as atherosclerosis, cardiovascular disease, neurological disorders, diabetes, and cancer. Furthermore, beta-glucans have been reported to possess immune-boosting and antitumor effects. ...They play a vi …
As a result, they help lower the risk of conditions such as atherosclerosis, cardiovascular disease, neurological disorders, diabetes, and …
Microbial-induced trained immunity for cancer immunotherapy.
Vuscan P, Kischkel B, Joosten LAB, Netea MG. Vuscan P, et al. Pharmacol Rev. 2025 Sep;77(5):100074. doi: 10.1016/j.pharmr.2025.100074. Epub 2025 Jun 12. Pharmacol Rev. 2025. PMID: 40616857 Free article. Review.
In this review, we explore the intricate landscape of myeloid cells in cancer and examine how microbial ligands, such as the Bacillus Calmette-Guerin vaccine and beta-glucan, reprogram both bone marrow progenitors and tissue-resident myeloid cells to enhance inflamm …
In this review, we explore the intricate landscape of myeloid cells in cancer and examine how microbial ligands, such as the Bacillus …
Utility and Pitfalls of beta-D-Glucan for Diagnosis and Response Monitoring of Chronic Disseminated Candidiasis in Paediatric Cancer Patients.
Körholz KF, Hennies MT, Herbrüggen H, Krämer K, Ahlmann M, Fröhlich B, Schaumburg F, Wiesel T, Rath PM, Groll AH. Körholz KF, et al. Mycoses. 2025 Aug;68(8):e70102. doi: 10.1111/myc.70102. Mycoses. 2025. PMID: 40781933 Free PMC article.
BACKGROUND: beta-D-Glucan (BDG) is a useful but nonspecific biomarker in patients with suspected invasive fungal diseases including Pneumocystis pneumonia. ...PATIENTS AND METHODS: We describe the utility and pitfalls of serum BDG in paediatric cancer patients with …
BACKGROUND: beta-D-Glucan (BDG) is a useful but nonspecific biomarker in patients with suspected invasive fungal diseases including P …
Effects of Nichi BRITE beta-glucans as an onco-nutrition adjuvant in patients undergoing subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) for pancreatic, bile duct and duodenal malignancies: A clinical study.
Tsukada A, Miyajima I, Uchiyama S, Tabe D, Ikewaki N, Ichiyama K, Senthilkumar R, Iwasaki M, Abraham SJK. Tsukada A, et al. Nutrition. 2025 Sep;137:112811. doi: 10.1016/j.nut.2025.112811. Epub 2025 Apr 18. Nutrition. 2025. PMID: 40383031 Free article. Clinical Trial.
OBJECTIVES: Pancreatic cancers involve several challenges from difficulty in early diagnosis to high recurrence and mortality even after therapeutic interventions. ...Reduction in circulating cancer stem cells and pancreatic cancer marker CA19-9 inclines us t …
OBJECTIVES: Pancreatic cancers involve several challenges from difficulty in early diagnosis to high recurrence and mortality even af …
Tumor-associated macrophages in colon cancer immunotherapy: mechanisms, natural product interventions, and microenvironment remodeling.
He Q, Xiang L, Luo Y, Wang R, Zheng C, Gao Y, Yao H. He Q, et al. Front Immunol. 2025 Aug 12;16:1642091. doi: 10.3389/fimmu.2025.1642091. eCollection 2025. Front Immunol. 2025. PMID: 40873588 Free PMC article. Review.
Cannabidiol, Hydroxygenkwanin regulate TAM metabolism. Dietary agents like sulforaphane and beta-glucans modulate TAM-gut microbiome crosstalk. Nanoparticle-encapsulated phytochemicals enhance TAM-targeted delivery, while clinical translation requires standardized p …
Cannabidiol, Hydroxygenkwanin regulate TAM metabolism. Dietary agents like sulforaphane and beta-glucans modulate TAM-gut micr …
beta-glucan nanotubes improve oral doxorubicin delivery for colorectal cancer by microbiota-mediated colon targeting and reduced toxicity.
Gao Z, Hou X, Tang J, Qin Y, Hu J, Qiu Z, Wang Q, Chang C, Chen X, Shi Z, Zheng G, Du H, Song G, Meng Y. Gao Z, et al. Carbohydr Polym. 2026 Feb 15;374:124705. doi: 10.1016/j.carbpol.2025.124705. Epub 2025 Nov 17. Carbohydr Polym. 2026. PMID: 41371849
In this study, beta-glucan self-assembled nanotubes (beta-gluSNTs) were developed as colon-targeted delivery platforms, which enable microbiota-triggered drug release in the colon. ...Notably, due to encapsulation of DOX inside the beta-gluSNTs, the beta …
In this study, beta-glucan self-assembled nanotubes (beta-gluSNTs) were developed as colon-targeted delivery platforms, which …
Endogenous macrophages as "Trojan horses" for targeted oral delivery of mRNA-encoded cytokines in tumor microenvironment immunotherapy.
Luo PK, Chang WA, Peng SY, Chu LA, Chuang YH, Nguyen LD, Guo JS, Wei HC, Lai PL, Chang HH, Wang KL, Chen YH, Sung HW. Luo PK, et al. Biomaterials. 2026 Feb;325:123620. doi: 10.1016/j.biomaterials.2025.123620. Epub 2025 Aug 11. Biomaterials. 2026. PMID: 40803233
This study introduces a targeted oral immunotherapy strategy using IFN-gamma mRNA-loaded lipid nanoparticles conjugated with beta-glucans (IFN-gamma mRNA@betaGlus-LNPs), evaluated in a mouse model of triple-negative breast cancer. ...By harnessing the natural …
This study introduces a targeted oral immunotherapy strategy using IFN-gamma mRNA-loaded lipid nanoparticles conjugated with beta- …
Central trained immunity in the context of bladder cancer immunotherapy.
Chronopoulos J, Crespo M, Chavakis T. Chronopoulos J, et al. Cancer Cell. 2025 Aug 11;43(8):1394-1396. doi: 10.1016/j.ccell.2025.06.010. Epub 2025 Jul 3. Cancer Cell. 2025. PMID: 40614740
Two articles in Immunity and Cancer Cell describe that bladder cancer immunotherapy with Bacillus Calmette-Guerin (BCG) alone or in combination with beta-glucan, another agonist of trained immunity (TRIM), involves reprogramming of bone marrow (BM) hematopoie …
Two articles in Immunity and Cancer Cell describe that bladder cancer immunotherapy with Bacillus Calmette-Guerin (BCG) alone …
Inhibition of osteosarcoma lung metastases by beta-glucan and CD40 agonist is mediated by activation of macrophages and NK cells.
Shrestha P, Shrestha R, Kleinerman ES. Shrestha P, et al. J Immunother Cancer. 2025 Oct 13;13(10):e012510. doi: 10.1136/jitc-2025-012510. J Immunother Cancer. 2025. PMID: 41083282 Free PMC article.
Pretreatment with beta-glucan prevented tumor cell seeding in the lungs. In tumor-bearing mice, beta-glucan treatment significantly suppressed tumor growth and prolonged overall survival. beta-glucan treatment increased activated pro-inflammatory M1-like macr …
Pretreatment with beta-glucan prevented tumor cell seeding in the lungs. In tumor-bearing mice, beta-glucan treatment signific …
59 results