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Adolescent cannabis use and psychological distress from 2013 to 2023: A population-based study in Ontario, Canada.
McDonald AJ, Doggett A, Bondy SJ, Colman I, Cook S, Hamilton HA, Kurdyak P, Leatherdale ST, Myran DT, Rehm J, Wickens CM, MacKillop J, Halladay J. McDonald AJ, et al. Addiction. 2026 Jan 28. doi: 10.1111/add.70333. Online ahead of print. Addiction. 2026. PMID: 41603606
BACKGROUND AND AIMS: Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th-century data, when cannabis was significantly less potent th …
BACKGROUND AND AIMS: Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. dep …
Research on Eating and Adolescent Lifestyle (REAL) 2.0: 15-year follow-up study of eating disorders and weight-related trajectories, mental health and substance use health from early adolescence to early adulthood-a Canadian cohort profile.
Obeid N, Buchholz A, Bradley AH, Mistry N, Vaillancourt T, Colman I, Tasca GA, Corace K, Maras D, Goldfield G. Obeid N, et al. BMJ Open. 2026 Jan 12;16(1):e103434. doi: 10.1136/bmjopen-2025-103434. BMJ Open. 2026. PMID: 41526025 Free PMC article.
Regarding substance use, 16.9% engaged in hazardous drinking, 16.9% used cannabis daily or almost daily, and 4.3% reported daily tobacco use. FUTURE PLANS: REAL 2.0 has the potential to answer multiple research questions about several mental health outcomes, but its priori …
Regarding substance use, 16.9% engaged in hazardous drinking, 16.9% used cannabis daily or almost daily, and 4.3% reported daily toba …
Effect of Nonmedical Cannabis Legalization and Exposure to Retail Stores on Cannabis Harms : A Quasi-experimental Study.
Friesen EL, Pugliese M, MacDonald-Spracklin R, Manuel D, Wilson K, Hobin E, Pinto AD, Myran DT. Friesen EL, et al. Ann Intern Med. 2026 Jan;179(1):12-22. doi: 10.7326/ANNALS-25-01960. Epub 2025 Nov 25. Ann Intern Med. 2026. PMID: 41285008
OBJECTIVE: To examine the association between exposure to cannabis retail stores and cannabis-related harms. DESIGN: Population-based natural experiment examining cannabis-attributable emergency department (ED) visits between 2017 and 2022. ...In neighborhood …
OBJECTIVE: To examine the association between exposure to cannabis retail stores and cannabis-related harms. DESIGN: Populatio …
Deliberate self-harm and suicide in individuals with cannabis-related hospital contacts in Ontario, Canada.
Fabiano N, Vargatoth E, Pugliese M, MacDonald-Spracklin R, Willows M, Solmi M, Myran DT. Fabiano N, et al. Mol Psychiatry. 2025 Dec 9. doi: 10.1038/s41380-025-03339-9. Online ahead of print. Mol Psychiatry. 2025. PMID: 41366517
As the global prevalence of cannabis use disorder increases, there are concerns about its association with self-harm and suicide. ...In the secondary analysis, people with an alcohol related hospital contact were at a higher risk of self-harm relative to cannabis (a …
As the global prevalence of cannabis use disorder increases, there are concerns about its association with self-harm and suicide. ... …
A comparison of the prevalence of cannabis and alcohol use among drivers and passengers in British Columbia and Ontario, Canada.
Pei LX, Chan H, Besserer F, Eppler J, Lee J, MacPherson A, McGrath M, Ohle R, Taylor J, Vaillancourt C, Brubacher JR. Pei LX, et al. Accid Anal Prev. 2025 Nov;222:108242. doi: 10.1016/j.aap.2025.108242. Epub 2025 Sep 14. Accid Anal Prev. 2025. PMID: 40946545 Free article.
BACKGROUND: Similar to drink driving, the prevalence of driving under the influence of cannabis (DUIC) is expected to depend on the availability and cost of cannabis which would impact cannabis use in both drivers and passengers, and factors that specifically …
BACKGROUND: Similar to drink driving, the prevalence of driving under the influence of cannabis (DUIC) is expected to depend on the a …
Relative Risk of All-Cause Mortality Associated With Cannabis Use: A Systematic Review and Meta-Analysis of Cohort Studies.
Alimoradi Z, Lin CY, Myran DT, Solmi M, Pakpour AH. Alimoradi Z, et al. Health Sci Rep. 2025 Sep 26;8(10):e71212. doi: 10.1002/hsr2.71212. eCollection 2025 Oct. Health Sci Rep. 2025. PMID: 41017864 Free PMC article. Review.
BACKGROUND AND AIMS: Cannabis use has high prevalence and health burden. Although the effects of cannabis use have been studied in the literature, no systematic review and meta-analysis has measured its association with all-cause mortality. ...Study sample size was …
BACKGROUND AND AIMS: Cannabis use has high prevalence and health burden. Although the effects of cannabis use have been studie …
Restrictive measures and course of behavioral outcomes in representative adult Greek population during the COVID-19 pandemic: Results on functioning, coping, alcohol/substance abuse, smoking, gambling, pro-social activities and domestic violence from the largest multi-wave COVID-19 online national survey in Greece (COH-FIT).
Agorastos A, Christogiannis C, Mavridis D, Seitidis G, Kontouli KM, Tsokani S, Koutsiouroumpa O, Tsamakis K, Solmi M, Thompson T, Correll CU, Dragioti E, Bozikas VP. Agorastos A, et al. J Psychiatr Res. 2025 Oct;190:480-489. doi: 10.1016/j.jpsychires.2025.07.014. Epub 2025 Aug 22. J Psychiatr Res. 2025. PMID: 40886563 Free article.
Outcomes included functioning, subjective resilience, tobacco/alcohol/cannabis/substance consumption, gambling, domestic violence, time spent in different activities, importance of coping strategies and prosocial activity. ...T1-T3) drop in functioning and resilience score …
Outcomes included functioning, subjective resilience, tobacco/alcohol/cannabis/substance consumption, gambling, domestic violence, ti …
Cannabis use patterns and comparison trends in Canada.
Fischer B, Jutras-Aswad D, Le Foll B, Myran D. Fischer B, et al. Addiction. 2025 Oct;120(10):2156-2157. doi: 10.1111/add.70146. Epub 2025 Jul 13. Addiction. 2025. PMID: 40653443 No abstract available.
Cannabis and psychosis.
Li S, Solmi M, Myran DT, Fabiano N. Li S, et al. CMAJ. 2025 Aug 10;197(27):E810. doi: 10.1503/cmaj.250659. CMAJ. 2025. PMID: 40789593 Free PMC article. No abstract available.
Role of ketamine in the treatment of substance use disorders: A systematic review.
Janssen-Aguilar R, Meshkat S, Demchenko I, Zhang Y, Greenshaw A, Dunn W, Tanguay R, Mayo LM, Swainson J, Jetly R, Bhat V. Janssen-Aguilar R, et al. J Subst Use Addict Treat. 2025 Aug;175:209705. doi: 10.1016/j.josat.2025.209705. Epub 2025 May 3. J Subst Use Addict Treat. 2025. PMID: 40320049 Free article.
RESULTS: Among the 14 studies, 6 focused on alcohol, 3 on cocaine, 4 on opioids, and 1 on cannabis. Seven studies (50 %) combined KET with psychotherapy, while seven (50 %) focused solely on KET's pharmacological effects. ...In Opioid Use Disorder (OUD), high-dose KET psyc …
RESULTS: Among the 14 studies, 6 focused on alcohol, 3 on cocaine, 4 on opioids, and 1 on cannabis. Seven studies (50 %) combined KET …
81 results