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IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma.
Bolomsky A, Ceribelli M, Scheich S, Rinaldi K, Huang DW, Chakraborty P, Pham L, Wright GW, Hsiao T, Morris V, Choi J, Phelan JD, Holewinski RJ, Andresson T, Wisniewski J, Riley D, Pittaluga S, Hill E, Thomas CJ, Muppidi J, Young RM. Bolomsky A, et al. Cancer Cell. 2024 Jul 8;42(7):1185-1201.e14. doi: 10.1016/j.ccell.2024.05.026. Epub 2024 Jun 20. Cancer Cell. 2024. PMID: 38906156 Free PMC article.
ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response.
Bakr A, Della Corte G, Veselinov O, Kelekçi S, Chen MM, Lin YY, Sigismondo G, Iacovone M, Cross A, Syed R, Jeong Y, Sollier E, Liu CS, Lutsik P, Krijgsveld J, Weichenhan D, Plass C, Popanda O, Schmezer P. Bakr A, et al. Nucleic Acids Res. 2024 Jun 10;52(10):5698-5719. doi: 10.1093/nar/gkae233. Nucleic Acids Res. 2024. PMID: 38587186 Free PMC article.
ARID1A loss sensitizes colorectal cancer cells to floxuridine.
Xiang C, Wang Z, Yu Y, Han Z, Lu J, Pan L, Zhang X, Wang Z, He Y, Wang K, Peng W, Liu S, Song Y, Wu C. Xiang C, et al. Neoplasia. 2024 Dec;58:101069. doi: 10.1016/j.neo.2024.101069. Epub 2024 Oct 16. Neoplasia. 2024. PMID: 39418826 Free PMC article.
Selective Alanine Transporter Utilization Is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer.
Nie H, Liao L, Zielinski RJ, Gomez JA, Basi AV, Seeley EH, Tan L, Bilecz AJ, Zhou W, Liu H, Wang C, Wu S, Qi Y, Miyamoto T, Severi F, Goldman AR, Gu S, Sood AK, Jazaeri AA, Drapkin R, Claiborne DT, Zhang N, Lorenzi PL, Burks JK, Lengyel E, Gottlieb E, Zhang R. Nie H, et al. Cancer Res. 2025 Sep 15;85(18):3471-3489. doi: 10.1158/0008-5472.CAN-25-0654. Cancer Res. 2025. PMID: 40658600 Free PMC article.
ARID1A in Gynecologic Precancers and Cancers.
Morgan JE, Jaferi N, Shonibare Z, Huang GS. Morgan JE, et al. Reprod Sci. 2024 Aug;31(8):2150-2162. doi: 10.1007/s43032-024-01585-w. Epub 2024 May 13. Reprod Sci. 2024. PMID: 38740655 Review.
ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification.
Barnada SM, Giner de Gracia A, Morenilla-Palao C, López-Cascales MT, Scopa C, Waltrich FJ Jr, Mikkers HMM, Cicardi ME, Karlin J, Trotti D, Peterson KA, Brugmann SA, Santen GWE, McMahon SB, Herrera E, Trizzino M. Barnada SM, et al. Am J Hum Genet. 2024 Oct 3;111(10):2232-2252. doi: 10.1016/j.ajhg.2024.07.022. Epub 2024 Sep 2. Am J Hum Genet. 2024. PMID: 39226899 Free PMC article.
70 results