Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1986 1
1989 2
1990 2
1991 2
1992 1
1993 2
1994 1
1995 3
1996 1
1998 1
2001 1
2011 1
2016 1
2017 1
2018 2
2020 3
2021 1
2022 1
2023 1
2024 3
2025 4
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

34 results

Results by year

Filters applied: . Clear all
Page 1
Metabolomic and proteomic characterization of sng and pain phenotypes in fibromyalgia.
Hsu WH, Han DS, Ku WC, Chao YM, Chen CC, Lin YL. Hsu WH, et al. Eur J Pain. 2022 Feb;26(2):445-462. doi: 10.1002/ejp.1871. Epub 2021 Oct 26. Eur J Pain. 2022. PMID: 34608709 Free PMC article.
Furthermore, lactate, 2-methylmaleate and cotinine in urine and lactate, SM(d18:1/25:1), SM(d18:1/26:1) and prostaglandin D2 (PGD2) and PCYOX1, ITIH4, PFN1, LRG1, C8G, C8A, CP, CDH5 and DBH in serum could differentiate pain- (PG) and sng-dominant groups (SG). ...SM(d18:1/2 …
Furthermore, lactate, 2-methylmaleate and cotinine in urine and lactate, SM(d18:1/25:1), SM(d18:1/26:1) and prostaglandin D2 (PGD2) and PCYO …
C8A and C8B polymorphisms in Norwegians and Norwegian lapps.
Rogde S, Teisberg P, Olaisen B. Rogde S, et al. Hum Hered. 1989;39(2):81-8. doi: 10.1159/000153839. Hum Hered. 1989. PMID: 2759635
C8 inheritance patterns in 364 mother-child pairs formed the basis for evaluation of the existence of silent alleles (null alleles) in the genes determining the two known polymorphic C8 systems. While evidence for such alleles was not found in C8A (alpha …
C8 inheritance patterns in 364 mother-child pairs formed the basis for evaluation of the existence of silent alleles (null alleles) i …
A Point Mutation Creating a 3' Splice Site in C8A Is a Predominant Cause of C8alpha-gamma Deficiency in African Americans.
Densen P, Ackermann L, Saucedo L, Figueroa JE, Si ZH, Stoltzfus CM. Densen P, et al. J Immunol. 2020 Sep 15;205(6):1535-1539. doi: 10.4049/jimmunol.2000272. Epub 2020 Aug 7. J Immunol. 2020. PMID: 32769119 Free PMC article.
Two individuals were compound heterozygotes for a previously reported point mutation in exon 9. mRNA from the remaining six C8A alleles contained a 10 nt insertion between nt 992 and 993 corresponding to the junction between exons 6 and 7. ...In summary, we have identified …
Two individuals were compound heterozygotes for a previously reported point mutation in exon 9. mRNA from the remaining six C8A allel …
Linkage and association studies with C8A and C8B RFLPs on chromosome 1.
Rogde S, Gedde-Dahl T Jr, Teisberg P, Jonassen R, Høyheim B, Olaisen B. Rogde S, et al. Ann Hum Genet. 1992 Jul;56(3):233-42. doi: 10.1111/j.1469-1809.1992.tb01148.x. Ann Hum Genet. 1992. PMID: 1360193
Linkage relations for the C8A and C8B BamHI RFLPs have been investigated. A peak lod score of 4.52 at recombination fraction zero was obtained between the two C8 genes. ...There was no evidence of allelic association between the C8A and C8B BamHI RFLPs in 62 …
Linkage relations for the C8A and C8B BamHI RFLPs have been investigated. A peak lod score of 4.52 at recombination fraction zero was …
The C8A and C8B loci are closely linked on chromosome 1.
Rogde S, Olaisen B, Gedde-Dahl T Jr, Teisberg P. Rogde S, et al. Ann Hum Genet. 1986 May;50(2):139-44. doi: 10.1111/j.1469-1809.1986.tb01032.x. Ann Hum Genet. 1986. PMID: 3435043
Close linkage was demonstrated between the loci governing the polymorphisms of complement component C8 alpha-gamma (C8A) and beta (C8B). Both C8 loci were linked to the chromosome 1 marker loci PGM1 and Rh. The distance between the two …
Close linkage was demonstrated between the loci governing the polymorphisms of complement component C8 alpha-gam …
Combined transcriptomics and proteomics analysis reveals mechanisms underlying refractory lupus nephritis in children.
Wei Q, Li Y, Liu H, Guan W, Gong Y, Zeng Q, Lv Q, Zhang X, Yang L, Xu H, Sun L. Wei Q, et al. Clin Rheumatol. 2025 Aug;44(8):3177-3190. doi: 10.1007/s10067-025-07483-z. Epub 2025 Jul 4. Clin Rheumatol. 2025. PMID: 40613967
Finally, we obtained 7 DEGs/DAPs, including CD59, JAK1, VCAM1, C8A, PIGR, TGFBI and VTN. The functions and pathways associated with the DEGs/DAPs mainly associated with complement and coagulation cascades. ...CONCLUSIONS: According to our research findings, we have …
Finally, we obtained 7 DEGs/DAPs, including CD59, JAK1, VCAM1, C8A, PIGR, TGFBI and VTN. The functions and pathways associated with t …
Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D.
Hu X, Webb-Robertson BM, Parikh HM, Nakayasu ES, Onengut-Gumuscu S, Chen WM, Frazer-Abel A, Metz TO, Rich SS, Rewers MJ, Manichaikul A. Hu X, et al. Commun Biol. 2025 Sep 26;8(1):1366. doi: 10.1038/s42003-025-08739-9. Commun Biol. 2025. PMID: 41006577 Free PMC article.
Recent studies have reported the involvement of complement system proteins in the initiation and progression of islet autoimmunity (IA) in the study of Type 1 diabetes (T1D). ...Our study provides evidence for the potential biological roles of complement …
Recent studies have reported the involvement of complement system proteins in the initiation and progression of islet a …
Genetic control of the eighth component of complement.
Raum D, Spence MA, Balavitch D, Tideman S, Merritt AD, Taggart RT, Petersen BH, Day NK, Alper CA. Raum D, et al. J Clin Invest. 1979 Sep;64(3):858-65. doi: 10.1172/JCI109534. J Clin Invest. 1979. PMID: 468996 Free PMC article.
Using isoelectric focusing in polyacrylamide gel and a hemolytic assay for development of patterns, extensive, structural polymorphism in human C8 has been delineated. Two alleles, C8A and C8B, have been identified in orientals, with gene frequencies of 0.655 and 0. …
Using isoelectric focusing in polyacrylamide gel and a hemolytic assay for development of patterns, extensive, structural polymorphism in hu …
Expression of the complement C8 genes during interleukin-6-mediated in vitro induction of the acute-phase response.
Späth GF, Ramadori G, Rittner C, Schneider PM. Späth GF, et al. Exp Clin Immunogenet. 1995;12(1):53-60. Exp Clin Immunogenet. 1995. PMID: 7710765
The three chains of the human complement component C8-alpha, beta and gamma- are encoded by distinct structural genes. ...The expression pattern observed in the hepatoma cells characterizes C8 in vitro as a positive acute-phase protein. In addit …
The three chains of the human complement component C8-alpha, beta and gamma- are encoded by distinct structural …
The eighth component of human complement: molecular basis of C8A (C81) polymorphism.
Zhang L, Rittner C, Sodetz JM, Schneider PM, Kaufmann T. Zhang L, et al. Hum Genet. 1995 Sep;96(3):281-4. doi: 10.1007/BF00210407. Hum Genet. 1995. PMID: 7649542
Using an exon-specific polymerase chain reaction (PCR) followed by direct DNA sequence analysis we have analyzed the polymorphism of the alpha-chain of the eighth component of human complement (C8) at the DNA level. We found that two comm …
Using an exon-specific polymerase chain reaction (PCR) followed by direct DNA sequence analysis we have analyzed the polymorphism of …
34 results