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CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen.
Manfrevola F, Ferraro B, Sellitto C, Rocco D, Fasano S, Pierantoni R, Chianese R. Manfrevola F, et al. Cells. 2021 Jul 31;10(8):1956. doi: 10.3390/cells10081956. Cells. 2021. PMID: 34440724 Free PMC article.
The need to unveil molecular mechanisms underlying this state of infertility is, thus, impelling. Circular RNAs (circRNAs) are involved in microRNA (miRNA) inhibition by a sponge activity to protect mRNA targets. ...With the idea that motility perturbations could be rooted …
The need to unveil molecular mechanisms underlying this state of infertility is, thus, impelling. Circular RNAs (circRNAs) are involv …
Quantification of CatSper1 expression in human spermatozoa and relation to functional parameters.
Tamburrino L, Marchiani S, Vicini E, Muciaccia B, Cambi M, Pellegrini S, Forti G, Muratori M, Baldi E. Tamburrino L, et al. Hum Reprod. 2015 Jul;30(7):1532-44. doi: 10.1093/humrep/dev103. Epub 2015 May 15. Hum Reprod. 2015. PMID: 25983333
STUDY QUESTION: Is CatSper1 expression in human spermatozoa related to semen parameter values and sperm functions? ...Current knowledge is mostly based on low specificity CatSper inhibitors showing agonistic and toxic effects on human spermatozoa and is thus of little help …
STUDY QUESTION: Is CatSper1 expression in human spermatozoa related to semen parameter values and sperm functions? ...Current knowled …
Association of CATSPER1, SPATA16 and TEX11 genes polymorphism with idiopathic azoospermia and oligospermia risk in Iranian population.
Behvarz M, Rahmani SA, Siasi Torbati E, Danaei Mehrabad S, Bikhof Torbati M. Behvarz M, et al. BMC Med Genomics. 2022 Mar 5;15(1):47. doi: 10.1186/s12920-022-01197-w. BMC Med Genomics. 2022. PMID: 35248021 Free PMC article.
BACKGROUND: Male infertility is a heterogeneous disease which can occur due to spermatogenesis defects. The idiopathic azoospermia and oligospermia are the common cause of male infertility with unknown underlying molecular mechanisms. The aim of this study was to in …
BACKGROUND: Male infertility is a heterogeneous disease which can occur due to spermatogenesis defects. The idiopathic azoospermia an …
CatSper channel, sperm function and male fertility.
Singh AP, Rajender S. Singh AP, et al. Reprod Biomed Online. 2015 Jan;30(1):28-38. doi: 10.1016/j.rbmo.2014.09.014. Epub 2014 Oct 8. Reprod Biomed Online. 2015. PMID: 25457194 Review.
CatSper knockout models and application of patch clamp recordings have shown that it is indispensable for male fertility, and mutations and deletions in CatSper gene(s) may lead to infertility. In fact, mutations in CatSper1 and 2 have been identified in infertil …
CatSper knockout models and application of patch clamp recordings have shown that it is indispensable for male fertility, and mutations and …
The Detection of CatSper1 and CatSper3 Expression in Men with Normozoospermia and Asthenoteratozoospermia and Its Association with Sperm Parameters, Fertilization Rate, Embryo Quality.
Jalalabadi FN, Cheraghi E, Janatifar R, Momeni HR. Jalalabadi FN, et al. Reprod Sci. 2024 Mar;31(3):704-713. doi: 10.1007/s43032-023-01397-4. Epub 2023 Nov 13. Reprod Sci. 2024. PMID: 37957468
Reverse transcription-polymerase chain reaction was utilized to evaluate the mRNA expression of CatSper1 and CatSper3 in sperm in two patient groups: Normozoospermia (NOR; n = 32), and Asthenoteratozoospermia (AT; n = 22). ...However, a negative correlation was found betwe …
Reverse transcription-polymerase chain reaction was utilized to evaluate the mRNA expression of CatSper1 and CatSper3 in sperm in two …
Effect of selenium and pentoxifylline on expression of CATSPER1 and 2 genes and FSH/LH levels in treated mice by dexamethasone.
Kheradmand N, Kamkar R, Moshajjari M, Baazm M. Kheradmand N, et al. Andrologia. 2019 Jul;51(6):e13279. doi: 10.1111/and.13279. Epub 2019 Apr 14. Andrologia. 2019. PMID: 30983026
In this study, the effect of dexamethasone on expression of CATSPER1 and 2 genes was investigated. These two genes play an important role in sperm motility. ...Based on the results, dexamethasone decreases not only CATSPER1 and 2 gene expression but also serum level …
In this study, the effect of dexamethasone on expression of CATSPER1 and 2 genes was investigated. These two genes play an important …
In Silico Analysis of CatSper Family Genes and APOB Gene Regulation in Male Infertility.
Maurya S, Bhoi NR, Kesari KK, Roychoudhury S, Kumar D. Maurya S, et al. Adv Exp Med Biol. 2022;1391:323-332. doi: 10.1007/978-3-031-12966-7_18. Adv Exp Med Biol. 2022. PMID: 36472830
Sperm concentration and sperm motility are the two major causes of male infertility. Having spermatozoa in semen without motility or flagellum tail defect is a major concern needed to be investigated. ...Understanding the molecular mechanism(s) of regulations of the CatSpe …
Sperm concentration and sperm motility are the two major causes of male infertility. Having spermatozoa in semen without motility or …
Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia.
Jin ZR, Fang D, Liu BH, Cai J, Tang WH, Jiang H, Xing GG. Jin ZR, et al. Theranostics. 2021 Jan 1;11(6):2822-2844. doi: 10.7150/thno.51869. eCollection 2021. Theranostics. 2021. PMID: 33456575 Free PMC article.
Knockdown of CatSper1 in the testis tissues is sufficient to induce AZS in normal rats, and this action was validated by the reversal effects of CatSper1 overexpression. ...Acupuncture treatment like TEAS may be used as a promising complementary and alternative medi …
Knockdown of CatSper1 in the testis tissues is sufficient to induce AZS in normal rats, and this action was validated by the reversal …
Rotational motion and rheotaxis of human sperm do not require functional CatSper channels and transmembrane Ca2+ signaling.
Schiffer C, Rieger S, Brenker C, Young S, Hamzeh H, Wachten D, Tüttelmann F, Röpke A, Kaupp UB, Wang T, Wagner A, Krallmann C, Kliesch S, Fallnich C, Strünker T. Schiffer C, et al. EMBO J. 2020 Feb 17;39(4):e102363. doi: 10.15252/embj.2019102363. Epub 2020 Jan 19. EMBO J. 2020. PMID: 31957048 Free PMC article.
Here, we study the swimming behavior of sperm from healthy donors and from infertile patients that lack functional CatSper channels, using dark-field microscopy, optical tweezers, and microfluidics. ...
Here, we study the swimming behavior of sperm from healthy donors and from infertile patients that lack functional CatSper channels, …
Analysis of the correlation of CATSPER single nucleotide polymorphisms (SNPs) with idiopathic asthenospermia.
Shu F, Zhou X, Li F, Lu D, Lei B, Li Q, Yang Y, Yang X, Shi R, Mao X. Shu F, et al. J Assist Reprod Genet. 2015 Nov;32(11):1643-9. doi: 10.1007/s10815-015-0548-5. Epub 2015 Sep 8. J Assist Reprod Genet. 2015. PMID: 26354096 Free PMC article.
PURPOSE: Idiopathic asthenospermia is the most common type of male infertility. Although the mechanisms causing asthenospermia are complex, recent studies have indicated an important role of cation channel of sperm (CATSPER) gene downregulation or abnormality in the etiolo …
PURPOSE: Idiopathic asthenospermia is the most common type of male infertility. Although the mechanisms causing asthenospermia are co …
20 results