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2023 15
2024 31
2025 47
2026 20

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103 results

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Page 1
Single-cell RNA sequencing and transcriptomic analysis reveal key genes and regulatory mechanisms in sepsis.
Mo Q, Mo Q, Mo F. Mo Q, et al. Biotechnol Genet Eng Rev. 2024 Nov;40(3):1636-1658. doi: 10.1080/02648725.2023.2196475. Epub 2023 Apr 5. Biotechnol Genet Eng Rev. 2024. PMID: 37017187
Nine key genes associated with the development of sepsis, namely IL7R, CD3D, IL32, GPR183, HLA-DPB1, CD81, PEBP1, NCL, and ETS1 were screened, and the specific signaling mechanisms associated with the key genes causing sepsis were predicted. ...
Nine key genes associated with the development of sepsis, namely IL7R, CD3D, IL32, GPR183, HLA-DPB1, CD81, PEBP1, NCL, and ETS1 were …
Association of aging related genes and immune microenvironment with major depressive disorder.
Yan B, Liao P, Han Z, Zhao J, Gao H, Liu Y, Chen F, Lei P. Yan B, et al. J Affect Disord. 2025 Jan 15;369:706-717. doi: 10.1016/j.jad.2024.10.053. Epub 2024 Oct 16. J Affect Disord. 2025. PMID: 39419187
A comprehensive analysis further narrowed down the 8 ARG-DEGs to 4 key ARG-DEGs: MMP9, IL7R, S100B, and EGF. Immune infiltration analysis indicated significant differences in CD8(+) T cells, macrophages, neutrophils, Th2 cells, and TIL cells between MDD and control groups, …
A comprehensive analysis further narrowed down the 8 ARG-DEGs to 4 key ARG-DEGs: MMP9, IL7R, S100B, and EGF. Immune infiltration anal …
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes.
Levin N, Kim SP, Marquardt CA, Vale NR, Yu Z, Sindiri S, Gartner JJ, Parkhurst M, Krishna S, Lowery FJ, Zacharakis N, Levy L, Prickett TD, Benzine T, Ray S, Masi RV, Gasmi B, Li Y, Islam R, Bera A, Goff SL, Robbins PF, Rosenberg SA. Levin N, et al. J Immunother Cancer. 2024 May 30;12(5):e008645. doi: 10.1136/jitc-2023-008645. J Immunother Cancer. 2024. PMID: 38816232 Free PMC article.
Single-Cell Transcriptomic Profile of Innate Cell Populations in Mesenteric Lymph Nodes of Inflammatory Bowel Disease Patients.
Wils P, Habibi Kavashkohie MR, Sélos Guerra F, Landais S, Rubio M, Mehta H, Sarfati M, Chapuy L. Wils P, et al. Inflamm Bowel Dis. 2025 Jun 13;31(6):1649-1663. doi: 10.1093/ibd/izaf017. Inflamm Bowel Dis. 2025. PMID: 39982469 Free article.
Among NK/ILC clusters, we identified a cytotoxic ILC subset (IL7R, KLRD1, GNLY), previously not reported in MLNs, reminiscent of cytotoxic ILC1-like cells found in inflamed gut mucosa. ...
Among NK/ILC clusters, we identified a cytotoxic ILC subset (IL7R, KLRD1, GNLY), previously not reported in MLNs, reminiscent of cyto …
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes.
Tutino M, Yu NY, Hatzikotoulas K, Park YC, Kreitmaier P, Katsoula G, Berner R, Casteels K, Elding Larsson H, Kordonouri O, Ołtarzewski M, Szypowska A, Ott R, Weiss A, Winkler C, Zapardiel-Gonzalo J, Petrera A, Hauck SM, Bonifacio E, Ziegler AG, Zeggini E. Tutino M, et al. Nat Commun. 2025 Apr 22;16(1):3750. doi: 10.1038/s41467-025-58972-3. Nat Commun. 2025. PMID: 40263317 Free PMC article.
We show colocalization of pQTLs for CTRB1, APOBR, IL7R, CPA1, and PNLIPRP1 with Type 1 diabetes GWAS signals, and Mendelian randomization causally implicates each of these five proteins in the aetiology of Type 1 diabetes. ...
We show colocalization of pQTLs for CTRB1, APOBR, IL7R, CPA1, and PNLIPRP1 with Type 1 diabetes GWAS signals, and Mendelian randomiza …
Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches.
Zhang J, Jia Z, Zhang J, Mu X, Ai L. Zhang J, et al. Biol Direct. 2025 Apr 29;20(1):58. doi: 10.1186/s13062-025-00649-4. Biol Direct. 2025. PMID: 40302006 Free PMC article.
Using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine Recursive Feature Elimination (SVM-RFE), and Random Forest (RF) algorithms, we screened for seven potential diagnostic biomarkers with strong diagnostic capabilities: SMAD3, IL7R, IL1 …
Using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine Recursive Feature Elimination (SVM-RFE), and Rando …
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer.
Zu L, He J, Zhou N, Tang Q, Liang M, Xu S. Zu L, et al. Cell Death Dis. 2023 Dec 6;14(12):798. doi: 10.1038/s41419-023-06286-x. Cell Death Dis. 2023. PMID: 38057344 Free PMC article.
In addition, a six-gene signature (ADRB2, DPYSL2, IL7R, LIMCH1, PIK3R1, and SOX2) was subsequently established to predict NSCLC metastasis based on differentially expressed genes, three of which (DPYSL2, PIK3R1, LIMCH1) along with the transcriptional factors RB1 and TP63, …
In addition, a six-gene signature (ADRB2, DPYSL2, IL7R, LIMCH1, PIK3R1, and SOX2) was subsequently established to predict NSCLC metas …
103 results