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Year Number of Results
2016 2
2017 7
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2020 10
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43 results

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Page 1
Association between KIF1B rs17401966 genetic polymorphism and hepatocellular carcinoma susceptibility: an updated meta-analysis.
Luo YY, Zhang HP, Huang AL, Hu JL. Luo YY, et al. BMC Med Genet. 2019 Apr 4;20(1):59. doi: 10.1186/s12881-019-0778-y. BMC Med Genet. 2019. PMID: 30947687 Free PMC article.
BACKGROUND: Several studies have focused on the association between KIF1B rs17401966 polymorphism and susceptibility to hepatitis B virus-related (HBV-related) hepatocellular carcinoma (HCC), but the conclusions have been inconsistent. ...CONCLUSIONS: G-allele appears to b …
BACKGROUND: Several studies have focused on the association between KIF1B rs17401966 polymorphism and susceptibility to hepatitis B v …
Large-scale analysis reveals splicing biomarkers for tuberculosis progression and prognosis.
Lai H, Lyu M, Ruan H, Liu Y, Liu T, Lei S, Xiao Y, Zhang S, Ying B. Lai H, et al. Comput Biol Med. 2024 Mar;171:108187. doi: 10.1016/j.compbiomed.2024.108187. Epub 2024 Feb 19. Comput Biol Med. 2024. PMID: 38402840
Among 923 TB-progression related differential AS events (DASEs), 3 events (GET1-skipping exon (SE), TPD52-alternative first exons (AF) and TIMM10-alternative 5' splice site (A5)) were selected as candidate biomarkers; however, their predictive performance was limited. For TB prog …
Among 923 TB-progression related differential AS events (DASEs), 3 events (GET1-skipping exon (SE), TPD52-alternative first exons (AF) and T …
NBPF1 independently determine the risk stratification and prognosis of patients with neuroblastoma.
Zhang J, Zhao Y, Wang J, Sneh T, Yu Q, Zhou X, Gong C. Zhang J, et al. Genomics. 2020 Nov;112(6):3951-3957. doi: 10.1016/j.ygeno.2020.06.038. Epub 2020 Jul 1. Genomics. 2020. PMID: 32619576 Free article.
Significant negative correlations between NBPF1 and the expression of MYCN and AKT1S1, and positive correlations between NBPF1 and KIF1B expression were found, but only NBPF1 was an independent biomarker based on the construct of PPI for MYCN, NBPF1, KIF1B and AKT1S …
Significant negative correlations between NBPF1 and the expression of MYCN and AKT1S1, and positive correlations between NBPF1 and KIF1B …
Head and Neck Paragangliomas-A Genetic Overview.
Majewska A, Budny B, Ziemnicka K, Ruchała M, Wierzbicka M. Majewska A, et al. Int J Mol Sci. 2020 Oct 16;21(20):7669. doi: 10.3390/ijms21207669. Int J Mol Sci. 2020. PMID: 33081307 Free PMC article. Review.
We found that the etiology of the tumors in question is based on genetic changes in the form of either germinal or somatic mutations. 40% of PCC and PGL have a predisposing germline mutation (including VHL, SDHB, SDHD, RET, NF1, THEM127, MAX, SDHC, SDHA, SDHAF2, HIF2A, HRAS, K …
We found that the etiology of the tumors in question is based on genetic changes in the form of either germinal or somatic mutations. 40% of …
Exosomal circ0000549 promotes MNNG-induced gastric cancer through miR-15b-5p/KIF1B.
Liang Z, Gao Z, Zhang Y, Song J, Qian H, Xu X. Liang Z, et al. Int J Mol Med. 2026 May;57(5):114. doi: 10.3892/ijmm.2026.5785. Epub 2026 Mar 6. Int J Mol Med. 2026. PMID: 41789656 Free PMC article.
Circ0000549 functioned as a sponge for miR-15b-5p, leading to increased KIF1B expression and subsequent activation of the PI3K/AKT signaling pathway. Collectively, these findings reveal that exosomal circ0000549 promotes malignant transformation of GES-1 cells through the …
Circ0000549 functioned as a sponge for miR-15b-5p, leading to increased KIF1B expression and subsequent activation of the PI3K/AKT si …
KIF1Bβ suppresses hepatocellular carcinoma by transporting and secreting FBLN5 to attenuate the integrin pathway.
Gao C, Wang Y, Zhou G, Shi P, Wang JA, Wu J, Liao S, Yan H, Qiu Y, Yan H, Zeng T, Li R, Zhang Y, Cao P, Yang C, Ye J, Liang R, Wang Y, Cheng F, Hao K, Zhang J, Hu X, Guo R, Wang Q, He F, Li Y, Zhou G. Gao C, et al. Gut. 2026 Apr 7;75(5):1030-1042. doi: 10.1136/gutjnl-2025-336230. Gut. 2026. PMID: 41087058
RESULTS: We confirmed the association between 1p36.22 locus and HCC risk (p=4.99 10(-24)), and revealed that this locus is an eQTL of the kinesin family member 1B isoform beta (KIF1Bbeta) gene. Further, we demonstrated that KIF1Bbeta plays a tumour sup …
RESULTS: We confirmed the association between 1p36.22 locus and HCC risk (p=4.99 10(-24)), and revealed that this locus is an eQTL of the …
Genetic and Clinical Profiles of Pheochromocytoma and Paraganglioma: A Single Center Study.
Ma X, Li M, Tong A, Wang F, Cui Y, Zhang X, Zhang Y, Chen S, Li Y. Ma X, et al. Front Endocrinol (Lausanne). 2020 Dec 11;11:574662. doi: 10.3389/fendo.2020.574662. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33362715 Free PMC article. Clinical Trial.
To detect the genetic and clinical profile of Chinese PPGL patients, we examined the variants of 12 known germline pathogenic genes (SDHA, SDHB, SDHC, SDHD, SDHAF2, FH, VHL, RET, NF1, MAX, TMEM127, and KIF1B) by next-generation sequencing and Sanger sequencing in 314 Chine …
To detect the genetic and clinical profile of Chinese PPGL patients, we examined the variants of 12 known germline pathogenic genes (SDHA, S …
Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y.
Yang J, Shao X, Jiang J, Sun Y, Wang L, Sun L. Yang J, et al. Cell Biol Int. 2018 Jul;42(7):867-876. doi: 10.1002/cbin.10954. Epub 2018 Mar 24. Cell Biol Int. 2018. PMID: 29465760
Key kinases in the PI3K/AKT and JAK/STAT pathways were downregulated by AP stimulation, while these downregulations were abrogated by miR-675 overexpression. KIF1B isoform beta (KIF1Bbeta) is proved to be a target of miR-675. In conclusion, AP was first identified to inhib …
Key kinases in the PI3K/AKT and JAK/STAT pathways were downregulated by AP stimulation, while these downregulations were abrogated by miR-67 …
tRNA-Derived Fragment tRF-18 Facilitates Cell Proliferation and Inhibits Cell Apoptosis via Modulating KIF1B in Papillary Thyroid Carcinoma.
Lu X, Wu W, Sun D, Sang J. Lu X, et al. Crit Rev Eukaryot Gene Expr. 2022;32(5):21-31. doi: 10.1615/CritRevEukaryotGeneExpr.2022040682. Crit Rev Eukaryot Gene Expr. 2022. PMID: 35993942
The interaction between tRF-18 and messenger RNA kinesin family member 1B (KIF1B) was validated via RNA immunoprecipitation assays and luciferase reporter assays. tRF-18 exhibited high expression in PTC tissues. ...Mechanistically, tRF-18 was co …
The interaction between tRF-18 and messenger RNA kinesin family member 1B (KIF1B) was validated via RNA i …
A case of juvenile-onset pheochromocytoma with KIF1B p.V1529M germline mutation.
Nezu M, Hirotsu Y, Amemiya K, Katsumata M, Watanabe T, Takizawa S, Inoue M, Mochizuki H, Hosaka K, Oyama T, Omata M. Nezu M, et al. Endocr J. 2022 Jun 28;69(6):705-716. doi: 10.1507/endocrj.EJ21-0475. Epub 2022 Jan 19. Endocr J. 2022. PMID: 35046208 Free article.
However, in 2020, the same research group reported that the cause of PCC in this family was a MAX germline mutation and was not due to the KIF1B mutation. In this study, we investigated the pathogenicity of a KIF1B germline mutation detected in a 26-year-old woman w …
However, in 2020, the same research group reported that the cause of PCC in this family was a MAX germline mutation and was not due to the …
43 results