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Page 1
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences.
Campione E, Lanna C, Cosio T, Rosa L, Conte MP, Iacovelli F, Romeo A, Falconi M, Del Vecchio C, Franchin E, Lia MS, Minieri M, Chiaramonte C, Ciotti M, Nuccetelli M, Terrinoni A, Iannuzzi I, Coppeda L, Magrini A, Bernardini S, Sabatini S, Rosapepe F, Bartoletti PL, Moricca N, Di Lorenzo A, Andreoni M, Sarmati L, Miani A, Piscitelli P, Valenti P, Bianchi L. Campione E, et al. Front Pharmacol. 2021 Jun 17;12:666600. doi: 10.3389/fphar.2021.666600. eCollection 2021. Front Pharmacol. 2021. PMID: 34220505 Free PMC article.
Immunomodulatory effect of bovine lactoferrin during SARS-CoV-2 infection.
da Silva AMV, Machado TL, Nascimento RS, Rodrigues MPMD, Coelho FS, Tubarão LN, da Rosa LC, Bayma C, Rocha VP, Frederico ABT, Silva J, Cunha DRABE, de Souza AF, de Souza RBG, Barros CA, Fiscina DDS, Ribeiro LCP, de Carvalho CAM, da Silva BJD, Muller R, Azamor T, Melgaço JG, Gonçalves RB, Ano Bom APD. da Silva AMV, et al. Front Immunol. 2024 Oct 17;15:1456634. doi: 10.3389/fimmu.2024.1456634. eCollection 2024. Front Immunol. 2024. PMID: 39483459 Free PMC article.
Early human milk lactoferrin during SARS-CoV-2 infection.
Briana DD, Papadopoulou A, Syridou G, Marchisio E, Kapsabeli E, Daskalaki A, Papaevangelou V. Briana DD, et al. J Matern Fetal Neonatal Med. 2022 Dec;35(25):6704-6707. doi: 10.1080/14767058.2021.1920010. Epub 2021 May 9. J Matern Fetal Neonatal Med. 2022. PMID: 33969775
Interaction of Pelargonium sidoides Compounds with Lactoferrin and SARS-CoV-2: Insights from Molecular Simulations.
Iacovelli F, Costanza G, Romeo A, Cosio T, Lanna C, Bagnulo A, Di Maio U, Sbardella A, Gaziano R, Grelli S, Squillaci E, Miani A, Piscitelli P, Bianchi L, Falconi M, Campione E. Iacovelli F, et al. Int J Environ Res Public Health. 2022 Apr 26;19(9):5254. doi: 10.3390/ijerph19095254. Int J Environ Res Public Health. 2022. PMID: 35564648 Free PMC article.
Lactoferrin for COVID-19 prevention, treatment, and recovery.
Bolat E, Eker F, Kaplan M, Duman H, Arslan A, Saritaş S, Şahutoğlu AS, Karav S. Bolat E, et al. Front Nutr. 2022 Nov 7;9:992733. doi: 10.3389/fnut.2022.992733. eCollection 2022. Front Nutr. 2022. PMID: 36419551 Free PMC article. Review.
Molecular mimicry of the receptor-binding domain of the SARS-CoV-2 spike protein: from the interaction of spike-specific antibodies with transferrin and lactoferrin to the antiviral effects of human recombinant lactoferrin.
Sokolov AV, Isakova-Sivak IN, Mezhenskaya DA, Kostevich VA, Gorbunov NP, Elizarova AY, Matyushenko VA, Berson YM, Grudinina NA, Kolmakov NN, Zabrodskaya YA, Komlev AS, Semak IV, Budevich AI, Rudenko LG, Vasilyev VB. Sokolov AV, et al. Biometals. 2023 Jun;36(3):437-462. doi: 10.1007/s10534-022-00458-6. Epub 2022 Nov 5. Biometals. 2023. PMID: 36334191 Free PMC article.
COVID-19 and early human milk lactoferrin.
Joob B, Wiwanitkit V. Joob B, et al. J Matern Fetal Neonatal Med. 2022 Dec;35(25):7707. doi: 10.1080/14767058.2021.1960971. Epub 2021 Aug 5. J Matern Fetal Neonatal Med. 2022. PMID: 34353215 No abstract available.
Lactoferrin for the treatment of COVID-19 (Review).
Wang Y, Wang P, Wang H, Luo Y, Wan L, Jiang M, Chu Y. Wang Y, et al. Exp Ther Med. 2020 Dec;20(6):272. doi: 10.3892/etm.2020.9402. Epub 2020 Oct 27. Exp Ther Med. 2020. PMID: 33199997 Free PMC article. Review.
Lactoferrin as Antiviral Treatment in COVID-19 Management: Preliminary Evidence.
Campione E, Lanna C, Cosio T, Rosa L, Conte MP, Iacovelli F, Romeo A, Falconi M, Del Vecchio C, Franchin E, Lia MS, Minieri M, Chiaramonte C, Ciotti M, Nuccetelli M, Terrinoni A, Iannuzzi I, Coppeta L, Magrini A, Bernardini S, Sabatini S, Rosapepe F, Bartoletti PL, Moricca N, Di Lorenzo A, Andreoni M, Sarmati L, Miani A, Piscitelli P, Squillaci E, Valenti P, Bianchi L. Campione E, et al. Int J Environ Res Public Health. 2021 Oct 19;18(20):10985. doi: 10.3390/ijerph182010985. Int J Environ Res Public Health. 2021. PMID: 34682731 Free PMC article.
Can lactoferrin boost human immunity against COVID-19?
AlKhazindar M, Elnagdy SM. AlKhazindar M, et al. Pathog Glob Health. 2020 Jul;114(5):234-235. doi: 10.1080/20477724.2020.1779514. Epub 2020 Jun 12. Pathog Glob Health. 2020. PMID: 32529963 Free PMC article. No abstract available.
Bovine lactoferrin for the prevention of COVID-19 infection in health care personnel: a double-blinded randomized clinical trial (LF-COVID).
Navarro R, Paredes JL, Tucto L, Medina C, Angles-Yanqui E, Nario JC, Ruiz-Cabrejos J, Quintana JL, Turpo-Espinoza K, Mejia-Cordero F, Aphang-Lam M, Florez J, Carrasco-Escobar G, Ochoa TJ. Navarro R, et al. Biometals. 2023 Jun;36(3):463-472. doi: 10.1007/s10534-022-00477-3. Epub 2022 Dec 7. Biometals. 2023. PMID: 36474100 Free PMC article. Clinical Trial.
Effect of Lactoferrin on Clinical Outcomes of Hospitalized Patients with COVID-19: The LAC Randomized Clinical Trial.
Matino E, Tavella E, Rizzi M, Avanzi GC, Azzolina D, Battaglia A, Becco P, Bellan M, Bertinieri G, Bertoletti M, Casciaro GF, Castello LM, Colageo U, Colangelo D, Comolli D, Costanzo M, Croce A, D'Onghia D, Della Corte F, De Mitri L, Dodaro V, Givone F, Gravina A, Grillenzoni L, Gusmaroli G, Landi R, Lingua A, Manzoni R, Marinoni V, Masturzo B, Minisini R, Morello M, Nelva A, Ortone E, Paolella R, Patti G, Pedrinelli A, Pirisi M, Ravizzi L, Rizzi E, Sola D, Sola M, Tonello N, Tonello S, Topazzo G, Tua A, Valenti P, Vaschetto R, Vassia V, Zecca E, Zublena N, Manzoni P, Sainaghi PP. Matino E, et al. Nutrients. 2023 Mar 4;15(5):1285. doi: 10.3390/nu15051285. Nutrients. 2023. PMID: 36904283 Free PMC article. Clinical Trial.
Beneficial Effects on Exercise Capacity Associated with a Combination of Lactoferrin, Lysozyme, Lactobacillus, Resveratrol, Vitamins, and Oligoelements in Patients with Post-COVID-19 Syndrome: A Single-Center Retrospective Study.
Marra AM, Giardino F, Anniballo A, Ferazzoli S, Salzano A, Arcopinto M, D'Assante R, De Mare A, Esposito G, Saldamarco L, Rurgo S, Sarnelli G, Cittadini A. Marra AM, et al. J Clin Med. 2024 Jul 29;13(15):4444. doi: 10.3390/jcm13154444. J Clin Med. 2024. PMID: 39124710 Free PMC article.
Erratum: "Effect of lactoferrin treatment on symptoms and physical performance in long COVID patients: a randomised, double-blind, placebo-controlled trial". Anne-Lotte Redel, Fatana Miry, Merel Elise Hellemons, Laurien Maria Amarentia Oswald and Gerrit Johannes Braunstahl. ERJ Open Res 2024; 10: 00031-2024.
[No authors listed] [No authors listed] ERJ Open Res. 2025 Feb 3;11(1):50031-2024. doi: 10.1183/23120541.50031-2024. eCollection 2025 Jan. ERJ Open Res. 2025. PMID: 39902266 Free PMC article.