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2022 3
2023 35
2024 8

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MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults.
Bennett DA, Parish S, Millwood IY, Guo Y, Chen Y, Turnbull I, Yang L, Lv J, Yu C, Davey Smith G, Wang Y, Wang Y, Peto R, Collins R, Walters RG, Li L, Chen Z, Clarke R; China Kadoorie Biobank (CKB) Study Collaborative Group. Bennett DA, et al. Int J Epidemiol. 2023 Dec 25;52(6):1862-1869. doi: 10.1093/ije/dyad147. Int J Epidemiol. 2023. PMID: 37898918 Free PMC article.
BACKGROUND: The relevance of folic acid for stroke prevention in low-folate populations such as in China is uncertain. Genetic studies of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which increases plasma homocysteine (tHcy) levels, could cla …
BACKGROUND: The relevance of folic acid for stroke prevention in low-folate populations such as in China is uncertain. Genetic studies of th …
Association of methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms with serum folate, cobalanin and homocysteine concentrations in Greek adults.
Mazokopakis EE, Papadomanolaki MG, Papadakis JA. Mazokopakis EE, et al. Scand J Clin Lab Invest. 2023 Apr;83(2):69-73. doi: 10.1080/00365513.2023.2167232. Epub 2023 Jan 20. Scand J Clin Lab Invest. 2023. PMID: 36662122
Methylene tetrahydrofolate reductase (MTHFR) is a key enzyme of homocysteine metabolism participating in the folate cycle. ...
Methylene tetrahydrofolate reductase (MTHFR) is a key enzyme of homocysteine metabolism participating in the folate cycle. ...
Correlation analysis of age and MTHFR C677T polymorphism with sperm motility and sperm DNA integrity.
Xin Z, Han N, Jin H. Xin Z, et al. Cell Mol Biol (Noisy-le-grand). 2023 Jun 30;69(6):110-115. doi: 10.14715/cmb/2023.69.6.17. Cell Mol Biol (Noisy-le-grand). 2023. PMID: 37605581
Hence, the purpose of this study was to investigate the effects of age and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on the forward progressive sperm motility and sperm DNA integrity. ...
Hence, the purpose of this study was to investigate the effects of age and methylenetetrahydrofolate reductase (MTHFR) C677T p …
MTHFR C677T and A1298C polymorphism's effect on risk of colorectal cancer in Lynch syndrome.
Wiik MU, Negline M, Beisvåg V, Clapham M, Holliday E, Dueñas N, Brunet J, Pineda M, Bonifaci N, Aretz S, Klinkhammer H, Spier I, Perne C, Mayr A, Valle L, Lubinski J, Sjursen W, Scott RJ, Talseth-Palmer BA. Wiik MU, et al. Sci Rep. 2023 Nov 1;13(1):18783. doi: 10.1038/s41598-023-44120-8. Sci Rep. 2023. PMID: 37914736 Free PMC article.
It is speculated that multiple genetic and environmental factors contribute to this variability, including two single nucleotide polymorphisms (SNPs) in the methylenetetrahydrofolate reductase (MTHFR) gene: C677T (rs1801133) and A1298C (rs1801131). ...
It is speculated that multiple genetic and environmental factors contribute to this variability, including two single nucleotide polymorphis …
Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults.
Wang X, Wang Y, Ma X, Zhou S, Xu J, Guo Y, Liu L, Liu Y, Gao L, Yuan L. Wang X, et al. Exp Gerontol. 2023 Jul;178:112208. doi: 10.1016/j.exger.2023.112208. Epub 2023 May 23. Exp Gerontol. 2023. PMID: 37201763 Free article.
The present study was designed to explore the gender-specific independent and combined impacts of solute carrier family 19 member 1 (SLC19A1) and methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms on oxidative stress biomarkers in older adults. ...CON …
The present study was designed to explore the gender-specific independent and combined impacts of solute carrier family 19 member 1 (SLC19A1 …
ALDH2 rs671 and MTHFR rs1801133 polymorphisms are risk factors for arteriosclerosis in multiple arteries.
Cai N, Li C, Gu X, Zeng W, Liu J, Zeng G, Zhong J, Zhu J, Hong H. Cai N, et al. BMC Cardiovasc Disord. 2023 Jun 24;23(1):319. doi: 10.1186/s12872-023-03354-0. BMC Cardiovasc Disord. 2023. PMID: 37355582 Free PMC article.
BACKGROUND: Arteriosclerosis in multiple arteries has long been associated with heightened cardiovascular risk. Acetaldehyde dehydrogenase 2 (ALDH2) and methylenetetrahydrofolate reductase (MTHFR) play an important role in the pathogenesis of arteriosclerosis by par …
BACKGROUND: Arteriosclerosis in multiple arteries has long been associated with heightened cardiovascular risk. Acetaldehyde dehydrogenase 2 …
MTHFR C677T Polymorphism, Plasma Homocysteine, and PDGF-AA Levels and Transcranial Doppler Velocity in Children With Sickle Cell Disease.
Mahmoud AA, Abd El Hady NMS, Rizk MS, El-Hawwary AM, Saleh NY. Mahmoud AA, et al. Indian Pediatr. 2023 Aug 15;60(8):651-654. Epub 2023 May 30. Indian Pediatr. 2023. PMID: 37260067 Free article.
OBJECTIVE: To evaluate the effect of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on plasma homocysteine (tHcy) and platelet-derived growth factor (PDGF-AA) levels in children with sickle cell disease (SCD), and ascertain their role in predicting h …
OBJECTIVE: To evaluate the effect of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on plasma homocysteine (tH …
41 results