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2004 1
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2010 3
2011 6
2012 6
2013 6
2014 7
2015 6
2016 3
2017 4
2018 5
2019 2
2020 3
2021 3
2022 7
2023 5
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2026 2

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Page 1
Risk of Coronary Artery Disease Associated With Transitions in Metabolic Health in a Clinical Cohort of 69 272.
Shuey MM, Levinson RT, Vogel ME, Farber-Eger E, Huang S, Harrel FE Jr, Hasty AH, Brown JD, Silver HJ, Koethe JR, Beckman JA, Brown NJ, Niswender KD, Cox NJ, Wells QS. Shuey MM, et al. Among authors: niswender kd. J Am Heart Assoc. 2025 Dec 2;14(23):e037597. doi: 10.1161/JAHA.124.037597. Epub 2025 Nov 24. J Am Heart Assoc. 2025. PMID: 41283206 Free PMC article.
RISING STARS: Effects of a GLP-1 receptor polymorphism on responses to liraglutide.
Mashayekhi M, Safa BI, Nian H, Devin JK, Gamboa JL, Yu C, Chen R, Beckman JA, Koethe JR, Silver HJ, Niswender K, Luther JM, Brown NJ. Mashayekhi M, et al. Among authors: niswender k. J Endocrinol. 2025 Oct 23;267(1):e250174. doi: 10.1530/JOE-25-0174. Print 2025 Oct 1. J Endocrinol. 2025. PMID: 41042549 Free PMC article. Clinical Trial.
Glucagon-like peptide-1 receptor signaling deficiency exacerbates hematopoietic stem cell graft rejection in mice.
Rusznak M, Sierra-Hernandez D, Dupuy C, Toki S, Wu AY, Rao U, Abney M, Zhang J, Hu Q, Warren CM, Drucker DJ, Niswender KD, Engelhardt B, Kim TK, Gibson-Corley KN, Cahill KN, Cooke KR, Peebles RS Jr. Rusznak M, et al. Among authors: niswender kd. J Immunol. 2026 Jan 21;215(1):vkaf251. doi: 10.1093/jimmun/vkaf251. J Immunol. 2026. PMID: 40990163 Free PMC article.
Regional and systemic adipose mass and peripheral conduit artery function.
Wakeham DJ, Beckman BE, Mashayekhi M, Luther JM, Garner EM, Perkins B, Gottlieb J, Niswender K, Hearon CM Jr, Brown NJ, Beckman JA. Wakeham DJ, et al. Among authors: niswender k. Diabetes Res Clin Pract. 2025 Sep;227:112408. doi: 10.1016/j.diabres.2025.112408. Epub 2025 Aug 6. Diabetes Res Clin Pract. 2025. PMID: 40774652 Free PMC article.
The Role of Serum Free Fatty Acids in Endothelium-Dependent Microvascular Function.
Sullivan AE, Courvan MCS, Ada AW, Wasserman DH, Niswender KD, Shardelow EM, Wells EK, Wells QS, Freiberg MS, Beckman JA. Sullivan AE, et al. Among authors: niswender kd. Endocrinol Diabetes Metab. 2025 Mar;8(2):e70031. doi: 10.1002/edm2.70031. Endocrinol Diabetes Metab. 2025. PMID: 39888728 Free PMC article. Clinical Trial.
Impact of metabolic and weight components on incident asthma using a real-world cohort.
Bloodworth MH, Staso PJ, Huang S, Farber-Eger E, Niswender KD, Harrell FE Jr, Wells QS, Bacharier LB, Shuey MM, Cahill KN. Bloodworth MH, et al. Among authors: niswender kd. Ann Allergy Asthma Immunol. 2024 Dec;133(6):660-666.e5. doi: 10.1016/j.anai.2024.09.005. Epub 2024 Sep 16. Ann Allergy Asthma Immunol. 2024. PMID: 39293715 Free PMC article.
The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adipose.
Mashayekhi M, Sheng Q, Bailin SS, Massier L, Zhong J, Shi M, Wanjalla CN, Wang TJ, Ikizler TA, Niswender KD, Gabriel CL, Palacios J, Turgeon-Jones R, Reynolds CF, Luther JM, Brown NJ, Das S, Dahlman I, Mosley JD, Koethe JR, Rydén M, Bachmann KN, Shah RV. Mashayekhi M, et al. Among authors: niswender kd. Obesity (Silver Spring). 2024 Aug;32(8):1526-1540. doi: 10.1002/oby.24064. Epub 2024 Jul 5. Obesity (Silver Spring). 2024. PMID: 38967296 Free PMC article.
Time to Rethink the Approach to Treating Obesity.
Samuels JM, Patel MB, Niswender KD. Samuels JM, et al. Among authors: niswender kd. JAMA Surg. 2024 Aug 1;159(8):841-842. doi: 10.1001/jamasurg.2024.1502. JAMA Surg. 2024. PMID: 38865110
Effect of the glucagon-like peptide-1 receptor agonist liraglutide, compared to caloric restriction, on appetite, dietary intake, body fat distribution and cardiometabolic biomarkers: A randomized trial in adults with obesity and prediabetes.
Silver HJ, Olson D, Mayfield D, Wright P, Nian H, Mashayekhi M, Koethe JR, Niswender KD, Luther JM, Brown NJ. Silver HJ, et al. Among authors: niswender kd. Diabetes Obes Metab. 2023 Aug;25(8):2340-2350. doi: 10.1111/dom.15113. Epub 2023 May 15. Diabetes Obes Metab. 2023. PMID: 37188932 Free PMC article. Clinical Trial.
Obesity and Overweight: Probing Causes, Consequences, and Novel Therapeutic Approaches Through the American Heart Association's Strategically Focused Research Network.
Clark JM, Garvey WT, Niswender KD, Schmidt AM, Ahima RS, Aleman JO, Battarbee AN, Beckman J, Bennett WL, Brown NJ, Chandler-Laney P, Cox N, Goldberg IJ, Habegger KM, Harper LM, Hasty AH, Hidalgo BA, Kim SF, Locher JL, Luther JM, Maruthur NM, Miller ER, Sevick MA, Wells Q. Clark JM, et al. Among authors: niswender kd. J Am Heart Assoc. 2023 Feb 21;12(4):e027693. doi: 10.1161/JAHA.122.027693. Epub 2023 Feb 8. J Am Heart Assoc. 2023. PMID: 36752232 Free PMC article. Review.
Comparative effects of weight loss and incretin-based therapies on vascular endothelial function, fibrinolysis and inflammation in individuals with obesity and prediabetes: A randomized controlled trial.
Mashayekhi M, Beckman JA, Nian H, Garner EM, Mayfield D, Devin JK, Koethe JR, Brown JD, Cahill KN, Yu C, Silver H, Niswender K, Luther JM, Brown NJ. Mashayekhi M, et al. Among authors: niswender k. Diabetes Obes Metab. 2023 Feb;25(2):570-580. doi: 10.1111/dom.14903. Epub 2022 Nov 10. Diabetes Obes Metab. 2023. PMID: 36306151 Free PMC article. Clinical Trial.
A pragmatic low carbohydrate diet intervention changes neither carbohydrate consumption nor glycemia in adolescents and young adults with type 1 diabetes in a randomized trial.
Duffus SH, Slaughter JC, Cooley W, Sharif N, Rainer K, Coate KC, Jaser SS, Moore DJ, Niswender KD, Gregory JM. Duffus SH, et al. Among authors: niswender kd. Pediatr Diabetes. 2022 Nov;23(7):1088-1100. doi: 10.1111/pedi.13407. Epub 2022 Sep 5. Pediatr Diabetes. 2022. PMID: 36004391 Free PMC article. Clinical Trial.
Post-transplant diabetes mellitus following heart transplantation.
Newman JD, Schlendorf KH, Cox ZL, Zalawadiya SK, Powers AC, Niswender KD, Shah RV, Lindenfeld J. Newman JD, et al. Among authors: niswender kd. J Heart Lung Transplant. 2022 Nov;41(11):1537-1546. doi: 10.1016/j.healun.2022.07.011. Epub 2022 Jul 19. J Heart Lung Transplant. 2022. PMID: 35970647 Review.
Exploration of an alternative to body mass index to characterize the relationship between height and weight for prediction of metabolic phenotypes and cardiovascular outcomes.
Shuey MM, Huang S, Levinson RT, Farber-Eger E, Cahill KN, Beckman JA, Koethe JR, Silver HJ, Niswender KD, Cox NJ, Harrell FE Jr, Wells QS. Shuey MM, et al. Among authors: niswender kd. Obes Sci Pract. 2021 Aug 13;8(1):124-130. doi: 10.1002/osp4.543. eCollection 2022 Feb. Obes Sci Pract. 2021. PMID: 35127128 Free PMC article.
Specialized Medical Weight Management Intervention for High-Risk Obesity.
Srivastava G, Paris C, Johnson J, Barnes E, Cunningham BL, Stimson CJ, Niswender KD, Poon SJ. Srivastava G, et al. Among authors: niswender kd. J Health Econ Outcomes Res. 2021 Jul 1;8(2):1-5. doi: 10.36469/001c.24896. eCollection 2021. J Health Econ Outcomes Res. 2021. PMID: 34250178 Free PMC article.
Clinical Effects of Balanced Crystalloids vs Saline in Adults With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials.
Self WH, Evans CS, Jenkins CA, Brown RM, Casey JD, Collins SP, Coston TD, Felbinger M, Flemmons LN, Hellervik SM, Lindsell CJ, Liu D, McCoin NS, Niswender KD, Slovis CM, Stollings JL, Wang L, Rice TW, Semler MW; Pragmatic Critical Care Research Group. Self WH, et al. Among authors: niswender kd. JAMA Netw Open. 2020 Nov 2;3(11):e2024596. doi: 10.1001/jamanetworkopen.2020.24596. JAMA Netw Open. 2020. PMID: 33196806 Free PMC article. Clinical Trial.
Mechanistic Phase II Clinical Trial of Metformin in Pulmonary Arterial Hypertension.
Brittain EL, Niswender K, Agrawal V, Chen X, Fan R, Pugh ME, Rice TW, Robbins IM, Song H, Thompson C, Ye F, Yu C, Zhu H, West J, Newman JH, Hemnes AR. Brittain EL, et al. Among authors: niswender k. J Am Heart Assoc. 2020 Nov 17;9(22):e018349. doi: 10.1161/JAHA.120.018349. Epub 2020 Nov 10. J Am Heart Assoc. 2020. PMID: 33167773 Free PMC article. Clinical Trial.
Human PAH is characterized by a pattern of lipid-related insulin resistance.
Hemnes AR, Luther JM, Rhodes CJ, Burgess JP, Carlson J, Fan R, Fessel JP, Fortune N, Gerszten RE, Halliday SJ, Hekmat R, Howard L, Newman JH, Niswender KD, Pugh ME, Robbins IM, Sheng Q, Shibao CA, Shyr Y, Sumner S, Talati M, Wharton J, Wilkins MR, Ye F, Yu C, West J, Brittain EL. Hemnes AR, et al. Among authors: niswender kd. JCI Insight. 2019 Jan 10;4(1):e123611. doi: 10.1172/jci.insight.123611. JCI Insight. 2019. PMID: 30626738 Free PMC article.
Acute effects of insulin on circulating natriuretic peptide levels in humans.
Bachmann KN, Deger SM, Alsouqi A, Huang S, Xu M, Ferguson JF, Su YR, Niswender KD, Ikizler TA, Wang TJ. Bachmann KN, et al. Among authors: niswender kd. PLoS One. 2018 May 14;13(5):e0196869. doi: 10.1371/journal.pone.0196869. eCollection 2018. PLoS One. 2018. PMID: 29758041 Free PMC article. Clinical Trial.
Brief exposure to obesogenic diet disrupts brain dopamine networks.
Barry RL, Byun NE, Williams JM, Siuta MA, Tantawy MN, Speed NK, Saunders C, Galli A, Niswender KD, Avison MJ. Barry RL, et al. Among authors: niswender kd. PLoS One. 2018 Apr 26;13(4):e0191299. doi: 10.1371/journal.pone.0191299. eCollection 2018. PLoS One. 2018. PMID: 29698491 Free PMC article.
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
Bloodworth MH, Rusznak M, Pfister CC, Zhang J, Bastarache L, Calvillo SA, Chappell JD, Boyd KL, Toki S, Newcomb DC, Stier MT, Zhou W, Goleniewska K, Moore ML, Hartert TV, Niswender KD, Peebles RS Jr. Bloodworth MH, et al. Among authors: niswender kd. J Allergy Clin Immunol. 2018 Aug;142(2):683-687.e12. doi: 10.1016/j.jaci.2018.01.053. Epub 2018 Apr 17. J Allergy Clin Immunol. 2018. PMID: 29678751 Free PMC article.
Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell cytokine production in vivo.
Toki S, Goleniewska K, Reiss S, Zhang J, Bloodworth MH, Stier MT, Zhou W, Newcomb DC, Ware LB, Stanwood GD, Galli A, Boyd KL, Niswender KD, Peebles RS Jr. Toki S, et al. Among authors: niswender kd. J Allergy Clin Immunol. 2018 Nov;142(5):1515-1528.e8. doi: 10.1016/j.jaci.2017.11.043. Epub 2018 Jan 10. J Allergy Clin Immunol. 2018. PMID: 29331643 Free PMC article.
Discovery of a Novel Series of Orally Bioavailable and CNS Penetrant Glucagon-like Peptide-1 Receptor (GLP-1R) Noncompetitive Antagonists Based on a 1,3-Disubstituted-7-aryl-5,5-bis(trifluoromethyl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione Core.
Nance KD, Days EL, Weaver CD, Coldren A, Farmer TD, Cho HP, Niswender CM, Blobaum AL, Niswender KD, Lindsley CW. Nance KD, et al. Among authors: niswender kd. J Med Chem. 2017 Feb 23;60(4):1611-1616. doi: 10.1021/acs.jmedchem.6b01706. Epub 2017 Feb 3. J Med Chem. 2017. PMID: 28103022
The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview.
Jefferson AL, Gifford KA, Acosta LM, Bell SP, Donahue MJ, Davis LT, Gottlieb J, Gupta DK, Hohman TJ, Lane EM, Libon DJ, Mendes LA, Niswender K, Pechman KR, Rane S, Ruberg FL, Su YR, Zetterberg H, Liu D. Jefferson AL, et al. Among authors: niswender k. J Alzheimers Dis. 2016 Mar 8;52(2):539-59. doi: 10.3233/JAD-150914. J Alzheimers Dis. 2016. PMID: 26967211 Free PMC article.
Disgust proneness and associated neural substrates in obesity.
Watkins TJ, Di Iorio CR, Olatunji BO, Benningfield MM, Blackford JU, Dietrich MS, Bhatia M, Theiss JD, Salomon RM, Niswender K, Cowan RL. Watkins TJ, et al. Among authors: niswender k. Soc Cogn Affect Neurosci. 2016 Mar;11(3):458-65. doi: 10.1093/scan/nsv129. Epub 2015 Oct 10. Soc Cogn Affect Neurosci. 2016. PMID: 26454815 Free PMC article.
Disruption of Daily Rhythms by High-Fat Diet Is Reversible.
Branecky KL, Niswender KD, Pendergast JS. Branecky KL, et al. Among authors: niswender kd. PLoS One. 2015 Sep 14;10(9):e0137970. doi: 10.1371/journal.pone.0137970. eCollection 2015. PLoS One. 2015. PMID: 26366733 Free PMC article.
Central nervous system neuropeptide Y regulates mediators of hepatic phospholipid remodeling and very low-density lipoprotein triglyceride secretion via sympathetic innervation.
Rojas JM, Bruinstroop E, Printz RL, Alijagic-Boers A, Foppen E, Turney MK, George L, Beck-Sickinger AG, Kalsbeek A, Niswender KD. Rojas JM, et al. Among authors: niswender kd. Mol Metab. 2015 Jan 16;4(3):210-21. doi: 10.1016/j.molmet.2015.01.004. eCollection 2015 Mar. Mol Metab. 2015. PMID: 25737956 Free PMC article.
Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM).
Morris LC, Nance KD, Gentry PR, Days EL, Weaver CD, Niswender CM, Thompson AD, Jones CK, Locuson CW, Morrison RD, Daniels JS, Niswender KD, Lindsley CW. Morris LC, et al. Among authors: niswender kd. J Med Chem. 2014 Dec 11;57(23):10192-7. doi: 10.1021/jm501375c. Epub 2014 Dec 2. J Med Chem. 2014. PMID: 25423411 Free PMC article.
PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission.
de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, Ciccocioppo R. de Guglielmo G, et al. Among authors: niswender k. Neuropsychopharmacology. 2015 Mar;40(4):927-37. doi: 10.1038/npp.2014.268. Epub 2014 Sep 14. Neuropsychopharmacology. 2015. PMID: 25311134 Free PMC article.
Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.
Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD. Kocalis HE, et al. Among authors: niswender kd. Mol Metab. 2014 Feb 19;3(4):394-407. doi: 10.1016/j.molmet.2014.01.014. eCollection 2014 Jul. Mol Metab. 2014. PMID: 24944899 Free PMC article.
Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function.
Saunders C, Siuta M, Robertson SD, Davis AR, Sauer J, Matthies HJG, Gresch PJ, Airey D, Lindsley CW, Schetz JA, Niswender KD, Veenstra-Vanderweele JM, Galli A. Saunders C, et al. Among authors: niswender kd. Neurochem Int. 2014 Jul;73:113-121. doi: 10.1016/j.neuint.2013.09.015. Epub 2013 Sep 30. Neurochem Int. 2014. PMID: 24090638 Free PMC article.
Tissue-specific function of Period3 in circadian rhythmicity.
Pendergast JS, Niswender KD, Yamazaki S. Pendergast JS, et al. Among authors: niswender kd. PLoS One. 2012;7(1):e30254. doi: 10.1371/journal.pone.0030254. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22253927 Free PMC article.
Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding.
Speed N, Saunders C, Davis AR, Owens WA, Matthies HJ, Saadat S, Kennedy JP, Vaughan RA, Neve RL, Lindsley CW, Russo SJ, Daws LC, Niswender KD, Galli A. Speed N, et al. Among authors: niswender kd. PLoS One. 2011;6(9):e25169. doi: 10.1371/journal.pone.0025169. Epub 2011 Sep 28. PLoS One. 2011. PMID: 21969871 Free PMC article.
Neuroendocrine regulation of food intake.
Hagan S, Niswender KD. Hagan S, et al. Among authors: niswender kd. Pediatr Blood Cancer. 2012 Jan;58(1):149-53. doi: 10.1002/pbc.23376. Epub 2011 Sep 23. Pediatr Blood Cancer. 2012. PMID: 21953791 Review.
Basal insulin: beyond glycemia.
Niswender KD. Niswender KD. Postgrad Med. 2011 Jul;123(4):27-37. doi: 10.3810/pgm.2011.07.2301. Postgrad Med. 2011. PMID: 21680986 Review.
Insulin regulation of monoamine signaling: pathway to obesity.
Niswender KD, Daws LC, Avison MJ, Galli A. Niswender KD, et al. Neuropsychopharmacology. 2011 Jan;36(1):359-60. doi: 10.1038/npp.2010.167. Neuropsychopharmacology. 2011. PMID: 21116253 Free PMC article. No abstract available.
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
Siuta MA, Robertson SD, Kocalis H, Saunders C, Gresch PJ, Khatri V, Shiota C, Kennedy JP, Lindsley CW, Daws LC, Polley DB, Veenstra-Vanderweele J, Stanwood GD, Magnuson MA, Niswender KD, Galli A. Siuta MA, et al. Among authors: niswender kd. PLoS Biol. 2010 Jun 8;8(6):e1000393. doi: 10.1371/journal.pbio.1000393. PLoS Biol. 2010. PMID: 20543991 Free PMC article.
Obesity and the beta cell: lessons from leptin.
Niswender KD, Magnuson MA. Niswender KD, et al. J Clin Invest. 2007 Oct;117(10):2753-6. doi: 10.1172/JCI33528. J Clin Invest. 2007. PMID: 17909621 Free PMC article.