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Year Number of Results
2014 1
2015 11
2016 8
2017 4
2018 3
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2020 5
2021 5
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Page 1
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwink… See abstract for full author list ➔ Lagou V, et al. Nat Commun. 2021 Jan 5;12(1):24. doi: 10.1038/s41467-020-19366-9. Nat Commun. 2021. PMID: 33402679 Free PMC article.
Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic component underlying this phenomenon is not established. We assess sex-dimorphic (73,089/50,404 women and 67,506/47,806 …
Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, …
Phenotypic Variability with SLURP1 Mutations and Diffuse Palmoplantar Keratoderma.
Harjama L, Kettunen K, Elomaa O, Einarsdottir E, Heikkilä H, Kivirikko S, Lappalainen K, Saarela J, Alby C, Ranki A, Kere J, Hadj-Rabia S, Hannula-Jouppi K. Harjama L, et al. Acta Derm Venereol. 2020 Feb 25;100(4):adv00060. doi: 10.2340/00015555-3404. Acta Derm Venereol. 2020. PMID: 31944258 Free PMC article. No abstract available.
The secreted Ly-6/uPAR related protein-1 (SLURP1) stabilizes epithelial cell junctions and suppresses TNF-alpha-induced cytokine production.
Campbell G, Swamynathan S, Tiwari A, Swamynathan SK. Campbell G, et al. Biochem Biophys Res Commun. 2019 Oct 1;517(4):729-734. doi: 10.1016/j.bbrc.2019.07.123. Epub 2019 Aug 3. Biochem Biophys Res Commun. 2019. PMID: 31387745 Free PMC article.
The secreted Ly-6/uPAR related protein-1 (SLURP1) is an anti-angiogenic and anti-inflammatory peptide highly expressed by the mucosal epithelial cells. ...HCLE-SLURP1 cells also displayed a significant decrease in tumor necrosis factor-alpha (TNF-alpha …
The secreted Ly-6/uPAR related protein-1 (SLURP1) is an anti-angiogenic and anti-inflammatory peptide highly expressed …
Mal de Meleda: A Focused Review.
Perez C, Khachemoune A. Perez C, et al. Am J Clin Dermatol. 2016 Feb;17(1):63-70. doi: 10.1007/s40257-015-0157-1. Am J Clin Dermatol. 2016. PMID: 26445964 Review.
Mal de Meleda is a rare autosomal recessive palmoplantar keratoderma (PPK) disease with an estimated prevalence of 1:100,000. Clinically, the onset of the disease is typically soon after birth and features a transgrediens (plantar surface progressing to dorsal surface) and …
Mal de Meleda is a rare autosomal recessive palmoplantar keratoderma (PPK) disease with an estimated prevalence of 1:100,000. Clinica …
Emerging Role of Lymphocyte Antigen-6 Family of Genes in Cancer and Immune Cells.
Upadhyay G. Upadhyay G. Front Immunol. 2019 Apr 24;10:819. doi: 10.3389/fimmu.2019.00819. eCollection 2019. Front Immunol. 2019. PMID: 31068932 Free PMC article. Review.
Stem Cell Antigen-1 (Sca-1/Ly6A) was the first identified member of the Lymphocyte antigen-6 (Ly6) gene family. Sca-1 serves as a marker of cancer stem cells and tissue resident stem cells in mice. The Sca-1 gene is located on mouse chromosome 15. ...
Stem Cell Antigen-1 (Sca-1/Ly6A) was the first identified member of the Lymphocyte antigen-6 (Ly6) gene family. Sca-1 s …
Corneal Expression of SLURP-1 by Age, Sex, Genetic Strain, and Ocular Surface Health.
Swamynathan S, Delp EE, Harvey SA, Loughner CL, Raju L, Swamynathan SK. Swamynathan S, et al. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7888-96. doi: 10.1167/iovs.15-18206. Invest Ophthalmol Vis Sci. 2015. PMID: 26670825 Free PMC article.
PURPOSE: Although secreted Ly6/urokinase-type plasminogen activator receptor-related protein-1 (Slurp1) transcript is highly abundant in the mouse cornea, corresponding protein expression remains uncharacterized. ...Here, we examine mouse corneal Sl …
PURPOSE: Although secreted Ly6/urokinase-type plasminogen activator receptor-related protein-1 (Slurp1) transcript is h …
Mal de Meleda with homozygous mutation p.G86R in SLURP-1.
Jia WX, Zhang YY, Wu YD, Li WR, Cheng P, Bu WB, Li CR. Jia WX, et al. Int J Dermatol. 2020 Jun;59(6):751-754. doi: 10.1111/ijd.14807. Epub 2020 Feb 12. Int J Dermatol. 2020. PMID: 32048728 No abstract available.
40 results