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Page 1
Facts and Hopes on Cancer Immunotherapy for Small Cell Lung Cancer.
Zugazagoitia J, Osma H, Baena J, Ucero AC, Paz-Ares L. Zugazagoitia J, et al. Clin Cancer Res. 2024 Jul 15;30(14):2872-2883. doi: 10.1158/1078-0432.CCR-23-1159. Clin Cancer Res. 2024. PMID: 38630789 Review.
They include strategies to enhance the efficacy and/or reverse features that promote intrinsic resistance to PD1 axis inhibition (e.g., restoring MHC class I deficiency and targeting DNA damage response) and novel immunomodulatory agents beyond T-cell …
They include strategies to enhance the efficacy and/or reverse features that promote intrinsic resistance to PD1 axis inhibition (e.g., rest …
Bone marrow transplantation for MHC class I deficiency corrects T-cell immunity but dissociates natural killer cell repertoire formation from function.
Gao Y, Arkwright PD, Carter R, Cazaly A, Harrison RJ, Mant A, Cant AJ, Gadola S, Elliott TJ, Khakoo SI, Williams AP. Gao Y, et al. J Allergy Clin Immunol. 2016 Dec;138(6):1733-1736.e2. doi: 10.1016/j.jaci.2016.06.029. Epub 2016 Jul 27. J Allergy Clin Immunol. 2016. PMID: 27614800 Free PMC article. No abstract available.
PD-L1 and HLA-class I expression status and their therapeutic implication in oesophageal small-cell carcinoma.
Yamashita S, Abe H, Yamashita H, Yagi K, Seto Y, Ushiku T. Yamashita S, et al. Histopathology. 2023 Aug;83(2):264-275. doi: 10.1111/his.14924. Epub 2023 Apr 18. Histopathology. 2023. PMID: 37071391
Overall survival was significantly longer in patients with CPS 1 than in those with CPS <1. HLA-class I deficiency (>50% tumour cells) was noted in five cases (33%), with no significant correlation with PD-L1 expression status. Among the five MiN …
Overall survival was significantly longer in patients with CPS 1 than in those with CPS <1. HLA-class I deficienc
Phenotypic and pathomechanistic overlap between tapasin and TAP deficiencies.
Elsayed A, von Hardenberg S, Atschekzei F, Graalmann T, Jänke C, Witte T, Ringshausen FC, Sogkas G. Elsayed A, et al. J Allergy Clin Immunol. 2024 Oct;154(4):1069-1075. doi: 10.1016/j.jaci.2024.06.003. Epub 2024 Jun 10. J Allergy Clin Immunol. 2024. PMID: 38866210 Free article.
Alessandro Moretta and Transporter Associated With Antigen Processing (TAP) Deficiency: On Giant's Shoulders.
Zimmer J. Zimmer J. Front Immunol. 2019 Oct 15;10:2404. doi: 10.3389/fimmu.2019.02404. eCollection 2019. Front Immunol. 2019. PMID: 31681294 Free PMC article.
The laboratory hosting me for my Ph.D. described in 1994 the first human cases of TAP deficiency in two siblings with recurrent bacterial airway infections and a negative Human Leukocyte Antigen class I (HLA) serotyping. ...
The laboratory hosting me for my Ph.D. described in 1994 the first human cases of TAP deficiency in two siblings with recurren …
14 results