Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2001 4
2002 5
2003 6
2004 9
2005 5
2006 4
2007 7
2008 13
2009 13
2010 9
2011 15
2012 7
2013 19
2014 13
2015 14
2016 15
2017 13
2018 18
2019 21
2020 11
2021 18
2022 16
2023 17
2024 18
2025 15
2026 5

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

267 results

Results by year

Filters applied: . Clear all
Page 1
Signaling involved in hair follicle morphogenesis and development.
Rishikaysh P, Dev K, Diaz D, Qureshi WM, Filip S, Mokry J. Rishikaysh P, et al. Int J Mol Sci. 2014 Jan 22;15(1):1647-70. doi: 10.3390/ijms15011647. Int J Mol Sci. 2014. PMID: 24451143 Free PMC article. Review.
The Wnt pathway is considered to be the master regulator during hair follicle morphogenesis. Wnt signaling proceeds through EDA/EDAR/NF-kappaB signaling. NF-kappaB regulates the Wnt pathway and acts as a signal mediator by upregulating the expression of Shh ligand. ...
The Wnt pathway is considered to be the master regulator during hair follicle morphogenesis. Wnt signaling proceeds through EDA/EDAR/ …
The developmental basis of fingerprint pattern formation and variation.
Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ. Glover JD, et al. Cell. 2023 Mar 2;186(5):940-956.e20. doi: 10.1016/j.cell.2023.01.015. Epub 2023 Feb 9. Cell. 2023. PMID: 36764291 Free article.
Their spatial pattern is established by a Turing reaction-diffusion system, based on signaling between EDAR, WNT, and antagonistic BMP pathways. These signals resolve epithelial growth into bands of focalized proliferation under a precociously differentiated suprabasal lay …
Their spatial pattern is established by a Turing reaction-diffusion system, based on signaling between EDAR, WNT, and antagonistic BM …
Ectodysplasin signaling in development.
Mikkola ML, Thesleff I. Mikkola ML, et al. Cytokine Growth Factor Rev. 2003 Jun-Aug;14(3-4):211-24. doi: 10.1016/s1359-6101(03)00020-0. Cytokine Growth Factor Rev. 2003. PMID: 12787560 Review.
Two closely related isoforms of ectodysplasin, Eda-A1 and Eda-A2, have been described which bind to and activate two different receptors, Edar and X-linked Eda-A2 receptor (Xedar), respectively. Mutations in Eda, Edar or other molecules of this signaling pathway cau …
Two closely related isoforms of ectodysplasin, Eda-A1 and Eda-A2, have been described which bind to and activate two different receptors, …
The ectodysplasin pathway: from diseases to adaptations.
Sadier A, Viriot L, Pantalacci S, Laudet V. Sadier A, et al. Trends Genet. 2014 Jan;30(1):24-31. doi: 10.1016/j.tig.2013.08.006. Epub 2013 Sep 23. Trends Genet. 2014. PMID: 24070496 Review.
It comprises three main gene products: EDA, a ligand that belongs to the tumor necrosis factor (TNF)-alpha family, EDAR, a receptor related to the TNFalpha receptors, and EDARADD, a specific adaptor. This core pathway relies on downstream NF-kappaB pathway activation to re …
It comprises three main gene products: EDA, a ligand that belongs to the tumor necrosis factor (TNF)-alpha family, EDAR, a receptor r …
Ectodysplasin research--where to next?
Lefebvre S, Mikkola ML. Lefebvre S, et al. Semin Immunol. 2014 Jun;26(3):220-8. doi: 10.1016/j.smim.2014.05.002. Epub 2014 Jun 10. Semin Immunol. 2014. PMID: 24928340 Review.
Ectodysplasin A (EDA) - EDA receptor signalling and its pharmacological modulation.
Kowalczyk-Quintas C, Schneider P. Kowalczyk-Quintas C, et al. Cytokine Growth Factor Rev. 2014 Apr;25(2):195-203. doi: 10.1016/j.cytogfr.2014.01.004. Epub 2014 Jan 23. Cytokine Growth Factor Rev. 2014. PMID: 24508088 Free article. Review.
The EDA-EDAR system is an important effector of canonical Wnt signalling in developing skin appendages. ...Hijacking of the placental antibody transport system can help deliver active molecules to developing foetuses in a timely manner. EDAR agonists may serve to tr …
The EDA-EDAR system is an important effector of canonical Wnt signalling in developing skin appendages. ...Hijacking of the placental …
The Ectodysplasin and NFkappaB signalling pathways in odontogenesis.
Courtney JM, Blackburn J, Sharpe PT. Courtney JM, et al. Arch Oral Biol. 2005 Feb;50(2):159-63. doi: 10.1016/j.archoralbio.2004.11.019. Arch Oral Biol. 2005. PMID: 15721144 Review.
Hypohidrotic ectodermal dysplasia (HED) is a congenital disorder affecting organs of ectodermal origin including teeth, hair and sweat glands. Defects in Ectodysplasin (tabby), Edar (downless) and Edar associated death domain (Edaradd) (crinkled) cause HED in both h …
Hypohidrotic ectodermal dysplasia (HED) is a congenital disorder affecting organs of ectodermal origin including teeth, hair and sweat gland …
Edar signaling in the control of hair follicle development.
Botchkarev VA, Fessing MY. Botchkarev VA, et al. J Investig Dermatol Symp Proc. 2005 Dec;10(3):247-51. doi: 10.1111/j.1087-0024.2005.10129.x. J Investig Dermatol Symp Proc. 2005. PMID: 16382675 Free article. Review.
Here, we summarize the current knowledge of molecular mechanisms underlying the involvement of Edar signaling pathway in controlling hair follicle (HF) development and cycling. Genetic and experimental studies suggest that Edar signaling is involved in the control o …
Here, we summarize the current knowledge of molecular mechanisms underlying the involvement of Edar signaling pathway in controlling …
Effects of an Asian-specific nonsynonymous EDAR variant on multiple dental traits.
Park JH, Yamaguchi T, Watanabe C, Kawaguchi A, Haneji K, Takeda M, Kim YI, Tomoyasu Y, Watanabe M, Oota H, Hanihara T, Ishida H, Maki K, Park SB, Kimura R. Park JH, et al. J Hum Genet. 2012 Aug;57(8):508-14. doi: 10.1038/jhg.2012.60. Epub 2012 May 31. J Hum Genet. 2012. PMID: 22648185
One study demonstrated that a nonsynonymous single-nucleotide polymorphism (370V/A, rs3827760) in the ectodysplasin A receptor gene (EDAR) is associated with shoveling and double-shoveling grades of upper first incisors and tooth crown size. ...We also …
One study demonstrated that a nonsynonymous single-nucleotide polymorphism (370V/A, rs3827760) in the ectodysplasin A recep …
Ectodysplasin A in Biological Fluids and Diagnosis of Ectodermal Dysplasia.
Podzus J, Kowalczyk-Quintas C, Schuepbach-Mallepell S, Willen L, Staehlin G, Vigolo M, Tardivel A, Headon D, Kirby N, Mikkola ML, Schneider H, Schneider P. Podzus J, et al. J Dent Res. 2017 Feb;96(2):217-224. doi: 10.1177/0022034516673562. Epub 2016 Oct 11. J Dent Res. 2017. PMID: 28106506 Free article.
The tumor necrosis factor (TNF) family ligand ectodysplasin A (EDA) is produced as 2 full-length splice variants, EDA1 and EDA2, that bind to EDA receptor (EDAR) and X-linked EDA receptor (XEDAR/EDA2R), respectively. Inactivating mutations in Eda or Edar cause hypoh …
The tumor necrosis factor (TNF) family ligand ectodysplasin A (EDA) is produced as 2 full-length splice variants, EDA1 and EDA2, that bind t …
267 results