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51 results

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Page 1
Topical Losartan: Practical Guidance for Clinical Trials in the Prevention and Treatment of Corneal Scarring Fibrosis and Other Eye Diseases and Disorders.
Wilson SE. Wilson SE. J Ocul Pharmacol Ther. 2023 Apr;39(3):191-206. doi: 10.1089/jop.2022.0174. Epub 2023 Mar 6. J Ocul Pharmacol Ther. 2023. PMID: 36877777 Free PMC article. Review.
Research is also needed to explore the efficacy and safety of topical losartan for hypothesized treatment of transforming growth factor beta-induced (TGFBI)-related corneal dystrophies (Reis-Bucklers corneal dystrophy, lattice corneal dystrophy type …
Research is also needed to explore the efficacy and safety of topical losartan for hypothesized treatment of transforming growth factor beta …
Lattice corneal dystrophy type 1: an epithelial or stromal entity?
Lisch W, Seitz B. Lisch W, et al. Cornea. 2014 Oct;33(10):1109-12. doi: 10.1097/ICO.0000000000000202. Cornea. 2014. PMID: 25055147
PURPOSE: To evaluate the question whether lattice corneal dystrophy type 1 (LCD1) is of epithelial or stromal origin. METHODS: The landmark of advanced LCD1 shows central superficial haze and paracentral stromal lattice lines. ...
PURPOSE: To evaluate the question whether lattice corneal dystrophy type 1 (LCD1) is of epithelial or str …
An Arg124Cys mutation in transforming growth factor beta-induced gene associated with lattice corneal dystrophy type I in a Chinese pedigree.
Li F, He J, Bai H, Huang Y, Wang F, Tian L. Li F, et al. Indian J Ophthalmol. 2022 Jan;70(1):85-89. doi: 10.4103/ijo.IJO_33_21. Indian J Ophthalmol. 2022. PMID: 34937214 Free PMC article.
PURPOSE: To identify a clinical and genetic form of a large Chinese family with an autosomal-dominant lattice corneal dystrophy type I (LCD I). METHODS: The patients' eyes were examined on the basis of slit-lamp microscopy, and other clinical re …
PURPOSE: To identify a clinical and genetic form of a large Chinese family with an autosomal-dominant lattice corneal dystr …
Pseudoexfoliation syndrome in a patient with lattice corneal dystrophy.
Scuderi G, Nucci C, Tomei M. Scuderi G, et al. Int Ophthalmol. 1998-1999;22(4):195-6. doi: 10.1023/a:1006228910596. Int Ophthalmol. 1998. PMID: 10674861
We report the case of a 70-year-old female who presents lattice corneal dystrophy type I in association with pseudoexfoliation syndrome. This association has never been reported in patients not affected by systemic amyloidosis....
We report the case of a 70-year-old female who presents lattice corneal dystrophy type I in association w …
Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I.
Courtney DG, Atkinson SD, Moore JE, Maurizi E, Serafini C, Pellegrini G, Black GC, Manson FD, Yam GH, Macewen CJ, Allen EH, McLean WH, Moore CB. Courtney DG, et al. Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):977-85. doi: 10.1167/iovs.13-13279. Invest Ophthalmol Vis Sci. 2014. PMID: 24425855
PURPOSE: This study aimed to investigate the potency and specificity of short-interfering RNA (siRNA) treatment for TGFBI-Arg124Cys lattice corneal dystrophy type I (LCDI) using exogenous expression constructs in model systems and endogenous gen …
PURPOSE: This study aimed to investigate the potency and specificity of short-interfering RNA (siRNA) treatment for TGFBI-Arg124Cys latti …
New mode of treatment for lattice corneal dystrophy type I: corneal epithelial debridement and fibronectin eye drops.
Morita Y, Chikama T, Yamada N, Morishige N, Sonoda KH, Nishida T. Morita Y, et al. Jpn J Ophthalmol. 2012 Jan;56(1):26-30. doi: 10.1007/s10384-011-0104-5. Epub 2011 Nov 12. Jpn J Ophthalmol. 2012. PMID: 22080335
PURPOSE: The R124C mutation of the TGFBI gene gives rise to lattice corneal dystrophy type I, which is characterized by irregularity, turbulence, and opacity of the corneal epithelium. ...CONCLUSION: Despite the limitation of this study setting, …
PURPOSE: The R124C mutation of the TGFBI gene gives rise to lattice corneal dystrophy type I, which is ch …
Different phenotypes of lattice corneal dystrophy type I in patients with 417C>T (R124C) and 1762A>G (H572R) mutations in TGFBI (BIGH3).
Romero P, Moraga M, Herrera L. Romero P, et al. Mol Vis. 2010 Aug 13;16:1601-9. Mol Vis. 2010. PMID: 20806046 Free PMC article.
PURPOSE: To describe clinical data and to characterize mutations in the transforming growth factor beta-induced (TGFBI) gene in patients from three unrelated Chilean families with lattice corneal dystrophy type I (LCDI). METHODS: Snellen acuity …
PURPOSE: To describe clinical data and to characterize mutations in the transforming growth factor beta-induced (TGFBI) gene in patients fro …
Lattice corneal dystrophy type I without typical lattice lines: role of mutational analysis.
Yoshida S, Yoshida A, Nakao S, Emori A, Nakamura T, Fujisawa K, Kumano Y, Ishibashi T. Yoshida S, et al. Am J Ophthalmol. 2004 Mar;137(3):586-8. doi: 10.1016/j.ajo.2003.09.003. Am J Ophthalmol. 2004. PMID: 15013897
PURPOSE: To describe a Japanese patient with lattice corneal dystrophy type I (LCD I) who lacked the typical lattice lines. DESIGN: Interventional case report. ...
PURPOSE: To describe a Japanese patient with lattice corneal dystrophy type I (LCD I) who lacked the typi …
TGFBI gene mutations analysis in Chinese families with corneal dystrophies.
Wang X, Ying M, Fu C, Wang Y, Li N. Wang X, et al. Mol Med Rep. 2017 May;15(5):3198-3202. doi: 10.3892/mmr.2017.6414. Epub 2017 Mar 30. Mol Med Rep. 2017. PMID: 28358433
One family, with the R124C mutation, was diagnosed with lattice corneal dystrophy type 1, and the family with the H626R mutation was diagnosed with lattice corneal dystrophy type IIIB. ...
One family, with the R124C mutation, was diagnosed with lattice corneal dystrophy type 1, and the family …
51 results