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Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.
Gajek G, Hansen SWK, Jarych D, Kufelnicka-Babout M, Świerzko AS, Kobiela P, Szala-Poździej A, Chojnacka K, Sobczuk K, Domżalska-Popadiuk I, Mazela J, Kalinka J, Thiel S, Cedzyński M. Gajek G, et al. Front Immunol. 2024 Oct 11;15:1463651. doi: 10.3389/fimmu.2024.1463651. eCollection 2024. Front Immunol. 2024. PMID: 39464884 Free PMC article.
Furthermore, C/T or T/T genotypes at COLEC11 at rs3820897 (-9570 C>T) as well as MBL deficiency-associated MBL2 gene variants were more common in preterms diagnosed with RDS than among unaffected newborns. ...
Furthermore, C/T or T/T genotypes at COLEC11 at rs3820897 (-9570 C>T) as well as MBL deficiency-associated MBL2 gene varian …
Mannose-binding lectin gene sequence data in Kelantan population.
Zahidin MA, Mohd Noor NH, Johan MF, Abdullah AD, Zulkafli Z, Edinur HA. Zahidin MA, et al. Sci Data. 2024 Apr 30;11(1):435. doi: 10.1038/s41597-024-03274-4. Sci Data. 2024. PMID: 38688916 Free PMC article.
The human mannose-binding lectin (MBL) gene encodes a polymorphic protein that plays a crucial role in the innate immune response. Human MBL deficiency is associated with immunodeficiencies, and its variants have been linked to autoimmune and infectious diseases. .. …
The human mannose-binding lectin (MBL) gene encodes a polymorphic protein that plays a crucial role in the innate immune response. Human …
Humoral and cellular response to the third COVID-19 vaccination in patients with inborn errors of immunity or mannose-binding lectin deficiency : A prospective controlled open-label trial.
Vossen MG, Kartnig F, Mrak D, Simader E, Stiasny K, Kain R, Perkmann T, Haslacher H, Aberle JH, Heinz LX, Sieghart D, Burgmann H, Aletaha D, Scheinecker C, Bonelli M, Göschl L. Vossen MG, et al. Wien Klin Wochenschr. 2024 Nov;136(21-22):598-607. doi: 10.1007/s00508-024-02459-6. Epub 2024 Oct 24. Wien Klin Wochenschr. 2024. PMID: 39446203 Free PMC article. Clinical Trial.
In this prospective open-label clinical trial, we assessed the humoral immune response and the T-cell response in patients with IEI or severe MBL (mannose-binding lectin) deficiency (IEI/MBLdef) after three vaccinations. A total of 16 patients and 16 m …
In this prospective open-label clinical trial, we assessed the humoral immune response and the T-cell response in patients with IEI or sever …
Probing the interaction of mannose-binding lectin with healthy and sickle cell anemia red blood cells and its role in cellular biomechanics.
Lima C, Matos TLR, Souza THS, Amorim MSN, Santana OA, Moura P, Moura DS, Cabral Filho PE, Alencar LMR, Fontes A. Lima C, et al. Int J Biol Macromol. 2025 Apr;300:140118. doi: 10.1016/j.ijbiomac.2025.140118. Epub 2025 Jan 20. Int J Biol Macromol. 2025. PMID: 39842580
Furthermore, individuals with sickle cell anemia (SCA) and MBL deficiency seem more susceptible to vaso-occlusive crises, suggesting an MBL role on HbSS red blood cells (RBCs). ...
Furthermore, individuals with sickle cell anemia (SCA) and MBL deficiency seem more susceptible to vaso-occlusive crises, sugg …
Clinical exome sequencing elucidates underlying cause of death in sudden unexpected death of infants: two case reports.
Heathfield LJ, Martin LJ, van der Heyde Y, Molefe I, Ramesar R. Heathfield LJ, et al. Int J Legal Med. 2024 Mar;138(2):693-700. doi: 10.1007/s00414-023-03065-3. Epub 2023 Jul 24. Int J Legal Med. 2024. PMID: 37482595 Free PMC article.
In the second infant, a homozygous variant (rs201340753) was identified in MASP1, which was heterozygous in each parent, highlighting the value of including parental DNA in genetic studies. Whilst mannose-binding lectin deficiency could not be assessed …
In the second infant, a homozygous variant (rs201340753) was identified in MASP1, which was heterozygous in each parent, highlighting the va …