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1998 1
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2007 1
2009 1
2011 1
2012 1
2013 3
2014 5
2015 2
2016 4
2017 4
2018 4
2019 1
2020 8
2021 9
2022 2
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Nausea and vomiting in early pregnancy.
Festin M. Festin M. BMJ Clin Evid. 2014 Mar 19;2014:1405. BMJ Clin Evid. 2014. PMID: 24646807 Free PMC article. Review.
INTRODUCTION: More than half of pregnant women suffer from nausea and vomiting, which typically begins by the fourth week and disappears by the 16th week of pregnancy. The cause of nausea and vomiting in pregnancy is unknown, but may be due to the rise in human chor …
INTRODUCTION: More than half of pregnant women suffer from nausea and vomiting, which typically begins by the fourth week and disappears by …
Managing Migraine During Pregnancy and Lactation.
Wells RE, Turner DP, Lee M, Bishop L, Strauss L. Wells RE, et al. Curr Neurol Neurosci Rep. 2016 Apr;16(4):40. doi: 10.1007/s11910-016-0634-9. Curr Neurol Neurosci Rep. 2016. PMID: 27002079 Review.
Non-pharmacological migraine treatments can be instituted in advance of pregnancy as many are considered the safest options during pregnancy, but understanding the safety of medications and dietary supplements ensures appropriate care for the refractory migra …
Non-pharmacological migraine treatments can be instituted in advance of pregnancy as many are considered the safest options during …
Ondansetron use in early pregnancy and the risk of miscarriage.
Suarez EA, Boggess K, Engel SM, Stürmer T, Lund JL, Jonsson Funk M. Suarez EA, et al. Pharmacoepidemiol Drug Saf. 2021 Feb;30(2):103-113. doi: 10.1002/pds.5143. Epub 2020 Oct 12. Pharmacoepidemiol Drug Saf. 2021. PMID: 33000871
BACKGROUND: Ondansetron is commonly used to treat nausea and vomiting in pregnancy despite inconclusive evidence of its safety. ...CONCLUSIONS: We did not observe an increase in the risk of miscarriage for pregnancies exposed to ondansetron vs c …
BACKGROUND: Ondansetron is commonly used to treat nausea and vomiting in pregnancy despite inconclusive evidence of its saf
Ondansetron and pregnancy: Understanding the data.
Kennedy D. Kennedy D. Obstet Med. 2016 Mar;9(1):28-33. doi: 10.1177/1753495X15621154. Epub 2015 Dec 23. Obstet Med. 2016. PMID: 27512487 Free PMC article. Review.
Following the thalidomide tragedy of 55 years ago there is a particular awareness and sensitivity about these potential risks, especially in relation to any medication used to treat NVP. Despite several studies showing no clear benefits of ondansetron over other NVP treatm …
Following the thalidomide tragedy of 55 years ago there is a particular awareness and sensitivity about these potential risks, especially in …
Interventions for treating hyperemesis gravidarum: a Cochrane systematic review and meta-analysis.
Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, Berghella V. Boelig RC, et al. J Matern Fetal Neonatal Med. 2018 Sep;31(18):2492-2505. doi: 10.1080/14767058.2017.1342805. Epub 2017 Jul 11. J Matern Fetal Neonatal Med. 2018. PMID: 28614956 Review.
INTRODUCTION: While nausea and vomiting in early pregnancy are very common, affecting approximately 80% of the pregnancies, hyperemesis gravidarum is a severe form affecting 0.3-1.0% of the pregnancies. ...It is one of the most common indications for hospital …
INTRODUCTION: While nausea and vomiting in early pregnancy are very common, affecting approximately 80% of the pregnancies, hy …
Ondansetron in pregnancy revisited: Assessment and pregnancy labelling by the European Medicines Agency (EMA) & Pharmacovigilance Risk Assessment Committee (PRAC).
Damkier P, Kaplan YC, Shechtman S, Diav-Citrin O, Cassina M, Weber-Schoendorfer C. Damkier P, et al. Basic Clin Pharmacol Toxicol. 2021 Apr;128(4):579-582. doi: 10.1111/bcpt.13541. Epub 2020 Dec 16. Basic Clin Pharmacol Toxicol. 2021. PMID: 33275828 Free article.
The safety of ondansetron during pregnancy has-following publication of controversial and seemingly contradictory results-been subject to considerable academic turmoil, specifically with respect to the risk of congenital cardiac malformations and oral cleft. …
The safety of ondansetron during pregnancy has-following publication of controversial and seemingly contradictory resul …
Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT.
Robson S, McParlin C, Mossop H, Lie M, Fernandez-Garcia C, Howel D, Graham R, Ternent L, Steel A, Goudie N, Nadeem A, Phillipson J, Shehmar M, Simpson N, Tuffnell D, Campbell I, Williams R, O'Hara ME, McColl E, Nelson-Piercy C. Robson S, et al. Health Technol Assess. 2021 Nov;25(63):1-116. doi: 10.3310/hta25630. Health Technol Assess. 2021. PMID: 34782054 Free article. Clinical Trial.
Guidelines on the use of anti-sickness drugs exist, but evidence is limited about which drugs work the best. The EMPOWER (EMesis in Pregnancy - Ondansetron With mEtoClopRamide) trial aimed to compare the clinical effectiveness and cost-effectiveness of two anti-sick …
Guidelines on the use of anti-sickness drugs exist, but evidence is limited about which drugs work the best. The EMPOWER (EMesis in Pregn
Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta-analysis.
Picot C, Berard A, Grenet G, Ripoche E, Cucherat M, Cottin J. Picot C, et al. Birth Defects Res. 2020 Aug;112(13):996-1013. doi: 10.1002/bdr2.1705. Epub 2020 May 18. Birth Defects Res. 2020. PMID: 32420702
Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy. ...All comparative cohort and case-control studies on MCM, cardiac or orofacial defects and use of ondansetron during pregnancy were included. A team of paired re
Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy. ...All comparative cohort and case-c
Safety considerations surrounding use of treatment options for nausea and vomiting in pregnancy.
Koren G. Koren G. Expert Opin Drug Saf. 2017 Nov;16(11):1227-1234. doi: 10.1080/14740338.2017.1361403. Epub 2017 Aug 9. Expert Opin Drug Saf. 2017. PMID: 28749713 Review.
For the doxylamine/pyridoxine combination, H1blockers and metoclopramide there are large studies documenting fetal safety. There are also large reassuring studies on the fetal safety of ondansetron, but they are contrasted by some studies claiming increased f …
For the doxylamine/pyridoxine combination, H1blockers and metoclopramide there are large studies documenting fetal safety. There are …
Online information discrepancies regarding safety of medicine use during pregnancy and lactation: an IMI ConcePTION study.
Nörby U, Noël-Cuppers B, Hristoskova S, Desai M, Härmark L, Steel M, El-Haddad C, Douarin L. Nörby U, et al. Expert Opin Drug Saf. 2021 Sep;20(9):1117-1124. doi: 10.1080/14740338.2021.1935865. Epub 2021 Jun 8. Expert Opin Drug Saf. 2021. PMID: 34080506
Background: Inconsistencies in information on safety of medicine use during pregnancy and lactation can result in sub-optimal treatment for pregnant and lactating women, risks to the fetus or child and unnecessary weaning off breastfeeding. The objective of this stu …
Background: Inconsistencies in information on safety of medicine use during pregnancy and lactation can result in sub-optimal …
48 results