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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1993 2
1994 3
1996 1
1997 3
1998 2
1999 4
2000 3
2001 3
2002 5
2004 1
2005 2
2006 1
2007 1
2008 5
2009 6
2010 5
2011 5
2012 3
2013 7
2014 6
2015 5
2016 5
2017 3
2018 1
2024 0

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69 results

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Page 1
Tissue transglutaminase in Alzheimer's disease: involvement in pathogenesis and its potential as a therapeutic target.
Wilhelmus MM, de Jager M, Bakker EN, Drukarch B. Wilhelmus MM, et al. J Alzheimers Dis. 2014;42 Suppl 3:S289-303. doi: 10.3233/JAD-132492. J Alzheimers Dis. 2014. PMID: 24685636 Review.
Protein misfolding and the formation of stable insoluble protein complexes by self-interacting proteins, in particular amyloid-beta and tau protein, play a central role in the pathogenesis of Alzheimer's disease (AD). Unfortunately, the underlying mechanisms …
Protein misfolding and the formation of stable insoluble protein complexes by self-interacting proteins, in particular amyloid-beta and tau …
Transglutaminase 2 and neuroinflammation.
Ientile R, Currò M, Caccamo D. Ientile R, et al. Amino Acids. 2015 Jan;47(1):19-26. doi: 10.1007/s00726-014-1864-2. Epub 2014 Nov 15. Amino Acids. 2015. PMID: 25398223 Review.
Several findings emphasize the possible role of the TG2/NF-kappaB activation pathway in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. ...
Several findings emphasize the possible role of the TG2/NF-kappaB activation pathway in neurodegenerative diseases, including Alzheimer
Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views.
Wang DS, Dickson DW, Malter JS. Wang DS, et al. Int J Clin Exp Pathol. 2008 Jan 1;1(1):5-18. Int J Clin Exp Pathol. 2008. PMID: 18784819 Free PMC article.
Extensive protein cross-linking and aggregation are some of the most common molecular events in the pathogenesis of Alzheimer's disease (AD). Both beta-amyloid (Abeta) plaques and neurofibrillary tangles, which are extracellular and intracellular proteinaceou …
Extensive protein cross-linking and aggregation are some of the most common molecular events in the pathogenesis of Alzheimer's
[Transglutaminase and neurodegenerative diseases].
Liu Z, Zeng J, Zeng S, Tang B, Wang J. Liu Z, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Aug;32(4):562-6. doi: 10.3760/cma.j.issn.1003-9406.2015.04.025. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015. PMID: 26252108 Review. Chinese.
Notably, neurodegenerative diseases such as Huntington's disease, spinocerebellar ataxia, Alzheimer's disease and Parkinson's disease, have a close connection with TGase's role in the human body....
Notably, neurodegenerative diseases such as Huntington's disease, spinocerebellar ataxia, Alzheimer's disease and Parki …
Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
Martin A, Giuliano A, Collaro D, De Vivo G, Sedia C, Serretiello E, Gentile V. Martin A, et al. Amino Acids. 2013 Jan;44(1):111-8. doi: 10.1007/s00726-011-1081-1. Epub 2011 Sep 22. Amino Acids. 2013. PMID: 21938398 Review.
Transglutaminase activity has been hypothesized to be involved also in the pathogenetic mechanisms responsible for human neurodegenerative diseases. Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, supranuclear palsy, Huntington's …
Transglutaminase activity has been hypothesized to be involved also in the pathogenetic mechanisms responsible for human neurodegenerative d …
Transglutaminase 2 in neurodegenerative disorders.
Ruan Q, Johnson GV. Ruan Q, et al. Front Biosci. 2007 Jan 1;12:891-904. doi: 10.2741/2111. Front Biosci. 2007. PMID: 17127346 Review.
Most importantly, numerous studies have presented data demonstrating that dysregulation of TG2 may contribute to the pathogenesis of many neurodegenerative disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lat …
Most importantly, numerous studies have presented data demonstrating that dysregulation of TG2 may contribute to the pathogenesis of many ne …
Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain.
Wilhelmus MM, Grunberg SC, Bol JG, van Dam AM, Hoozemans JJ, Rozemuller AJ, Drukarch B. Wilhelmus MM, et al. Brain Pathol. 2009 Oct;19(4):612-22. doi: 10.1111/j.1750-3639.2008.00197.x. Epub 2008 Jul 31. Brain Pathol. 2009. PMID: 18673368 Free PMC article.
Alzheimer's disease (AD) is characterized by pathological lesions, in particular senile plaques (SPs), cerebral amyloid angiopathy (CAA) and neurofibrillary tangles (NFTs), predominantly consisting of self-aggregated proteins amyloid beta (Abeta) and tau, res
Alzheimer's disease (AD) is characterized by pathological lesions, in particular senile plaques (SPs), cerebral amyloid
Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
Zhang J, Wang S, Huang W, Bennett DA, Dickson DW, Wang D, Wang R. Zhang J, et al. Mol Neurobiol. 2016 Oct;53(8):5066-78. doi: 10.1007/s12035-015-9413-x. Epub 2015 Sep 19. Mol Neurobiol. 2016. PMID: 26386840 Free PMC article.
Alzheimer's disease (AD) is characterized by intracellular and extracellular protein aggregates, including microtubule-associated protein tau and cleavage product of amyloid precursor protein, beta-amyloid (Abeta). ...
Alzheimer's disease (AD) is characterized by intracellular and extracellular protein aggregates, including microtubule-
Transglutaminase activity as a possible therapeutical target in neurodegenerative diseases.
Iannaccone M, Titta F, Serretiello E, De Vivo G, Martin A, Gentile V. Iannaccone M, et al. Recent Pat CNS Drug Discov. 2013 Dec;8(3):235-42. doi: 10.2174/1574889808666131128105630. Recent Pat CNS Drug Discov. 2013. PMID: 24286449 Review.
Transglutaminase activity has been suggested to be involved in molecular mechanisms responsible for both physiological or pathological processes. For example, neurodegenerative diseases, such as Alzheimer's Disease, Parkinson's Disease, supranuclear palsy, Hu …
Transglutaminase activity has been suggested to be involved in molecular mechanisms responsible for both physiological or pathological proce …
Tissue transglutaminase is not a biochemical marker for Alzheimer's disease.
Wolf J, Jäger C, Lachmann I, Schönknecht P, Morawski M, Arendt T, Mothes T. Wolf J, et al. Neurobiol Aging. 2013 Nov;34(11):2495-8. doi: 10.1016/j.neurobiolaging.2013.05.008. Epub 2013 Jun 5. Neurobiol Aging. 2013. PMID: 23747046
Typical hallmarks of Alzheimer's disease (AD) are pathologic deposits in cortical and subcortical regions consisting of self-aggregated proteins such as amyloid-beta (Abeta) or tau. ...
Typical hallmarks of Alzheimer's disease (AD) are pathologic deposits in cortical and subcortical regions consisting of …
69 results