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1986 1
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Page 1
A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis.
Nyabam S, Wang Z, Thibault T, Oluseyi A, Basar R, Marshall L, Griffin M. Nyabam S, et al. Biochim Biophys Acta. 2016 Sep;1863(9):2234-44. doi: 10.1016/j.bbamcr.2016.05.012. Epub 2016 May 24. Biochim Biophys Acta. 2016. PMID: 27234323 Free article.
Cystic fibrosis (CF) is a genetic disorder caused by mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) for which there is no overall effective treatment. ...
Cystic fibrosis (CF) is a genetic disorder caused by mutation of the cystic fibrosis transmembrane conductance r
Recent advances in the development of tissue transglutaminase (TG2) inhibitors.
Badarau E, Collighan RJ, Griffin M. Badarau E, et al. Amino Acids. 2013 Jan;44(1):119-27. doi: 10.1007/s00726-011-1188-4. Epub 2011 Dec 13. Amino Acids. 2013. PMID: 22160259 Review.
However, upregulated levels of TG2 are associated with many disease states like celiac sprue, certain types of cancer, fibrosis, cystic fibrosis, multiple sclerosis, Alzheimer's, Huntington's and Parkinson's disease. ...
However, upregulated levels of TG2 are associated with many disease states like celiac sprue, certain types of cancer, fibrosis, cystic
Tissue transglutaminase activation modulates inflammation in cystic fibrosis via PPARgamma down-regulation.
Maiuri L, Luciani A, Giardino I, Raia V, Villella VR, D'Apolito M, Pettoello-Mantovani M, Guido S, Ciacci C, Cimmino M, Cexus ON, Londei M, Quaratino S. Maiuri L, et al. J Immunol. 2008 Jun 1;180(11):7697-705. doi: 10.4049/jimmunol.180.11.7697. J Immunol. 2008. PMID: 18490773
Cystic fibrosis (CF), the most common life-threatening inherited disease in Caucasians, is due to mutations in the CF transmembrane conductance regulator (CFTR) gene and is characterized by airways chronic inflammation and pulmonary infections. ...
Cystic fibrosis (CF), the most common life-threatening inherited disease in Caucasians, is due to mutations in the CF transmem
Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis.
Treharne KJ, Giles Best O, Mehta A. Treharne KJ, et al. FEBS Lett. 2009 Sep 3;583(17):2789-92. doi: 10.1016/j.febslet.2009.07.026. Epub 2009 Jul 18. FEBS Lett. 2009. PMID: 19619546 Free PMC article.
In the epithelial cell membrane, we show that manipulation of tgase2 function by monodansylcadaverine or retinoic acid (RA) alters the activity of a membrane-bound protein kinase, nucleoside diphosphate kinase (NDPK, nm23-H1/H2) that is known to control G-protein function. We fin …
In the epithelial cell membrane, we show that manipulation of tgase2 function by monodansylcadaverine or retinoic acid (RA) alters the activ …
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation.
Luciani A, Villella VR, Vasaturo A, Giardino I, Raia V, Pettoello-Mantovani M, D'Apolito M, Guido S, Leal T, Quaratino S, Maiuri L. Luciani A, et al. J Immunol. 2009 Aug 15;183(4):2775-84. doi: 10.4049/jimmunol.0900993. Epub 2009 Jul 22. J Immunol. 2009. PMID: 19625650
Cystic fibrosis (CF) is a monogenic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. ...
Cystic fibrosis (CF) is a monogenic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. ...
Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis.
Jeong EM, Son YH, Choi Y, Kim JH, Lee JH, Cho SY, Kim IG. Jeong EM, et al. Exp Mol Med. 2016 Nov 4;48(11):e267. doi: 10.1038/emm.2016.95. Exp Mol Med. 2016. PMID: 27811936 Free PMC article.
It has been reported that TG2 is involved in the pathogenesis of various inflammatory diseases including celiac disease, pulmonary fibrosis, cystic fibrosis, multiple sclerosis and sepsis. Recently, using a mouse model of bleomycin-induced lung fibrosis, we showed t …
It has been reported that TG2 is involved in the pathogenesis of various inflammatory diseases including celiac disease, pulmonary fibrosis, …
Transglutaminase in erythrocytes of cystic fibrosis patients.
Kamoun PP, Droin V. Kamoun PP, et al. Clin Chim Acta. 1986 Feb 15;154(3):219-22. doi: 10.1016/0009-8981(86)90034-3. Clin Chim Acta. 1986. PMID: 2869842
Transglutaminase activity was determined in erythrocytes from patients with cystic fibrosis and control subjects. No differences were observed between the two groups either for enzymatic activity or for the activating effect of calcium ions. The previously described …
Transglutaminase activity was determined in erythrocytes from patients with cystic fibrosis and control subjects. No differenc …
Production of recombinant human tissue transglutaminase using the baculovirus expression system, and its application for serological diagnosis of coeliac disease.
Osman AA, Richter T, Stern M, Conrad K, Henker J, Brandsch C, Zimmer KP, Mothes T. Osman AA, et al. Eur J Gastroenterol Hepatol. 2002 Nov;14(11):1217-23. doi: 10.1097/00042737-200211000-00009. Eur J Gastroenterol Hepatol. 2002. PMID: 12439116
For this, 35 patients with active CD were compared with 144 controls (18 patients with bioptically excluded CD, 89 blood donors, 30 patients with inflammatory bowel disease, and seven patients with cystic fibrosis). RESULTS: The ELISA using hu-tTG showed a sensitivi …
For this, 35 patients with active CD were compared with 144 controls (18 patients with bioptically excluded CD, 89 blood donors, 30 patients …
11 results