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Antitissue transglutaminase and antithyroid autoantibodies in children with Down syndrome and celiac disease.
Hansson T, Dahlbom I, Rogberg S, Nyberg BI, Dahlström J, Annerén G, Klareskog L, Dannaeus A. Hansson T, et al. J Pediatr Gastroenterol Nutr. 2005 Feb;40(2):170-4; discussion 125-7. doi: 10.1097/00005176-200502000-00016. J Pediatr Gastroenterol Nutr. 2005. PMID: 15699691
Of the 72 Down syndrome children, 11 under-went a small intestinal biopsy. RESULTS: Four of 72 children with Down syndrome were diagnosed as having CD and three of them had serum levels of immunoglobulin A tTG antibodies greater than 6 U/mL (668, 147 and 7 U/mL). On …
Of the 72 Down syndrome children, 11 under-went a small intestinal biopsy. RESULTS: Four of 72 children with Down syndrome wer …
Tissue transglutaminase autoantibodies and human leucocyte antigen in Down's syndrome patients with coeliac disease.
Agardh D, Nilsson A, Carlsson A, Kockum I, Lernmark A, Ivarsson SA. Agardh D, et al. Acta Paediatr. 2002;91(1):34-8. doi: 10.1080/080352502753457914. Acta Paediatr. 2002. PMID: 11883815
The association between autoantibodies against tissue transglutaminase (tTG) and human leucocyte antigen (HLA)-DQB1 alleles was tested in Down's syndrome (DS) patients with and without coeliac disease (CD). Immunoglobulin A (IgA) and G (IgG) anti-tTG were measured in radio …
The association between autoantibodies against tissue transglutaminase (tTG) and human leucocyte antigen (HLA)-DQB1 alleles was tested in Do …
Screening for celiac disease in Down's syndrome patients revealed cases of subtotal villous atrophy without typical for celiac disease HLA-DQ and tissue transglutaminase antibodies.
Uibo O, Teesalu K, Metskula K, Reimand T, Saat R, Sillat T, Reimand K, Talvik T, Uibo R. Uibo O, et al. World J Gastroenterol. 2006 Mar 7;12(9):1430-4. doi: 10.3748/wjg.v12.i9.1430. World J Gastroenterol. 2006. PMID: 16552815 Free PMC article.
AIM: To investigate the prevalence of celiac disease (CD) as well as CD marker antibodies and susceptibility HLA-DQ haplotypes in 134 karyotyped Down's syndrome (DS) patients. METHODS: Immunoglobulin A (IgA) and G (IgG) type anti-gliadin antibodies (AGA), IgA type anti-tis …
AIM: To investigate the prevalence of celiac disease (CD) as well as CD marker antibodies and susceptibility HLA-DQ haplotypes in 134 karyot …
Tissue transglutaminase antibodies are a useful serological marker for the diagnosis of celiac disease in patients with Down syndrome.
Shamaly H, Hartman C, Pollack S, Hujerat M, Katz R, Gideoni O, Shamir R. Shamaly H, et al. J Pediatr Gastroenterol Nutr. 2007 May;44(5):583-6. doi: 10.1097/MPG.0b013e3180320679. J Pediatr Gastroenterol Nutr. 2007. PMID: 17460490
BACKGROUND: Celiac disease (CD) is overrepresented among patients with Down syndrome (DS), who frequently lack any typical symptoms. Therefore, screening for CD is recommended in this high-risk group. ...
BACKGROUND: Celiac disease (CD) is overrepresented among patients with Down syndrome (DS), who frequently lack any typical symptoms. …
Prospective human leukocyte antigen, endomysium immunoglobulin A antibodies, and transglutaminase antibodies testing for celiac disease in children with Down syndrome.
Wouters J, Weijerman ME, van Furth AM, Schreurs MW, Crusius JB, von Blomberg BM, de Baaij LR, Broers CJ, Gemke RJ. Wouters J, et al. J Pediatr. 2009 Feb;154(2):239-42. doi: 10.1016/j.jpeds.2008.08.007. Epub 2008 Sep 25. J Pediatr. 2009. PMID: 18822429
OBJECTIVE: To assess the effect of a prospective screening strategy for the early diagnosis of celiac disease (CD) in children with Down syndrome (DS). STUDY DESIGN: Blood samples were taken from 155 children with DS. ...
OBJECTIVE: To assess the effect of a prospective screening strategy for the early diagnosis of celiac disease (CD) in children with Down …
The measurement of IgA and IgG transglutaminase antibodies in celiac disease: a comparison with current diagnostic methods.
Reeves GE, Burns C, Hall ST, Gleeson M, Lemmert K, Clancy RL. Reeves GE, et al. Pathology. 2000 Aug;32(3):181-5. Pathology. 2000. PMID: 10968391
In patients on no gluten restriction, there was 100% agreement between TGA and EMA, and 100% agreement between TGA and AGA for the IgA isotype. The false-positive rate for TGA was 53% in Down's syndrome patients and 25% in patients with systemic autoimmune disorders. ...
In patients on no gluten restriction, there was 100% agreement between TGA and EMA, and 100% agreement between TGA and AGA for the IgA isoty …