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Year Number of Results
1996 1
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Page 1
Transglutaminase inhibitors: a patent review.
Keillor JW, Apperley KY. Keillor JW, et al. Expert Opin Ther Pat. 2016;26(1):49-63. doi: 10.1517/13543776.2016.1115836. Epub 2015 Nov 24. Expert Opin Ther Pat. 2016. PMID: 26560530 Review.
Their protein-crosslinking activity has been linked to fibrosis and Huntington's disease, their glutamine deamidation activity has been related to celiac disease and their GTP-binding activity has been implicated in cancer. ...
Their protein-crosslinking activity has been linked to fibrosis and Huntington's disease, their glutamine deamidation activity …
[Transglutaminase and neurodegenerative diseases].
Liu Z, Zeng J, Zeng S, Tang B, Wang J. Liu Z, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Aug;32(4):562-6. doi: 10.3760/cma.j.issn.1003-9406.2015.04.025. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015. PMID: 26252108 Review. Chinese.
TGase has been found to contribute to a variety of important physiological and pathological processes and play a role in the pathogenesis of multiple diseases. Notably, neurodegenerative diseases such as Huntington's disease, spinocerebellar ataxia, Alzheimer's dise …
TGase has been found to contribute to a variety of important physiological and pathological processes and play a role in the pathogenesis of …
Type 2 Transglutaminase, mitochondria and Huntington's disease: menage a trois.
Altuntas S, D'Eletto M, Rossin F, Hidalgo LD, Farrace MG, Falasca L, Piredda L, Cocco S, Mastroberardino PG, Piacentini M, Campanella M. Altuntas S, et al. Mitochondrion. 2014 Nov;19 Pt A:97-104. doi: 10.1016/j.mito.2014.09.008. Epub 2014 Sep 28. Mitochondrion. 2014. PMID: 25262960 Review.
New insight into transglutaminase 2 and link to neurodegenerative diseases.
Min B, Chung KC. Min B, et al. BMB Rep. 2018 Jan;51(1):5-13. doi: 10.5483/bmbrep.2018.51.1.227. BMB Rep. 2018. PMID: 29187283 Free PMC article. Review.
Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (NDDs), which include amyotrophic lateral sclerosis (ALS), Alzheimer's, Parkinson's, Huntington's, and prion diseases. The transglutami …
Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (NDDs), w …
Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
Martin A, Giuliano A, Collaro D, De Vivo G, Sedia C, Serretiello E, Gentile V. Martin A, et al. Amino Acids. 2013 Jan;44(1):111-8. doi: 10.1007/s00726-011-1081-1. Epub 2011 Sep 22. Amino Acids. 2013. PMID: 21938398 Review.
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, supranuclear palsy, Huntington's disease and other polyglutamine diseases, are characterized in part by aberrant cerebral transglutaminase activity and by increased cross-linked proteins i …
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, supranuclear palsy, Huntington's disease and oth …
Transglutaminase activity as a possible therapeutical target in neurodegenerative diseases.
Iannaccone M, Titta F, Serretiello E, De Vivo G, Martin A, Gentile V. Iannaccone M, et al. Recent Pat CNS Drug Discov. 2013 Dec;8(3):235-42. doi: 10.2174/1574889808666131128105630. Recent Pat CNS Drug Discov. 2013. PMID: 24286449 Review.
For example, neurodegenerative diseases, such as Alzheimer's Disease, Parkinson's Disease, supranuclear palsy, Huntington's Disease and other polyglutamine diseases, are characterized in part by aberrant cerebral transglutaminase activity and by increased cross-link …
For example, neurodegenerative diseases, such as Alzheimer's Disease, Parkinson's Disease, supranuclear palsy, Huntington's Di …
Tissue transglutaminase: a novel pharmacological target in preventing toxic protein aggregation in neurodegenerative diseases.
Wilhelmus MM, van Dam AM, Drukarch B. Wilhelmus MM, et al. Eur J Pharmacol. 2008 May 13;585(2-3):464-72. doi: 10.1016/j.ejphar.2008.01.059. Epub 2008 Mar 18. Eur J Pharmacol. 2008. PMID: 18417122 Review.
Alzheimer's disease, Parkinson's disease and Huntington's disease are neurodegenerative diseases, characterized by the accumulation and deposition of neurotoxic protein aggregates. ...So far, increased levels and activity of tissue transglutaminase (tTG), the best c …
Alzheimer's disease, Parkinson's disease and Huntington's disease are neurodegenerative diseases, characterized by the accumul …
Tissue transglutaminase: a possible role in neurodegenerative diseases.
Lesort M, Tucholski J, Miller ML, Johnson GV. Lesort M, et al. Prog Neurobiol. 2000 Aug;61(5):439-63. doi: 10.1016/s0301-0082(99)00052-0. Prog Neurobiol. 2000. PMID: 10748319 Review.
Recent findings have provided evidence that dysregulation of tissue transglutaminase may contribute to the pathology of several neurodegenerative conditions including Alzheimer's disease and Huntington's disease. In both of these diseases tissue transglutaminase and …
Recent findings have provided evidence that dysregulation of tissue transglutaminase may contribute to the pathology of several neurodegener …
78 results