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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1976 2
1977 1
1978 1
1979 1
1980 2
1982 3
1983 5
1984 4
1985 8
1986 5
1987 6
1988 6
1989 5
1990 8
1991 11
1992 9
1993 11
1994 11
1995 10
1996 11
1997 9
1998 9
1999 19
2000 6
2001 8
2002 6
2003 8
2004 12
2005 12
2006 27
2007 17
2008 27
2009 30
2010 31
2011 39
2012 24
2013 32
2014 27
2015 26
2016 43
2017 38
2018 35
2019 28
2020 6
2022 0
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Search Results

564 results
Results by year
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Page 1
Transglutaminase-Mediated Conjugations.
Anami Y, Tsuchikama K. Anami Y, et al. Methods Mol Biol. 2020;2078:71-82. doi: 10.1007/978-1-4939-9929-3_5. Methods Mol Biol. 2020. PMID: 31643050
Prostate transglutaminase: a unique transglutaminase and its role in prostate cancer.
Jiang WG, Ablin RJ. Jiang WG, et al. Biomark Med. 2011 Jun;5(3):285-91. doi: 10.2217/bmm.11.36. Biomark Med. 2011. PMID: 21657838 Review.
Recent years have seen an expansion of interest in this enzyme, which is intriguingly expressed in prostate tissues and prostate cancer. In recent studies, the molecule has been found to have a diverse impact on prostate cancer cell growth, migration and invasivenes …
Recent years have seen an expansion of interest in this enzyme, which is intriguingly expressed in prostate tissues and prostate cancer
Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction.
Furini G, Verderio EAM. Furini G, et al. Med Sci (Basel). 2019 Jan 4;7(1):5. doi: 10.3390/medsci7010005. Med Sci (Basel). 2019. PMID: 30621228 Free PMC article. Review.
Heparan sulfate proteoglycans (HSPGs), syndecan-4 (Sdc4) especially, have been suggested as potential partners of transglutaminase-2 (TG2) in kidney and cardiac fibrosis, metastatic cancer, neurodegeneration and coeliac disease. The proposed role for HSPGs in the trafficki …
Heparan sulfate proteoglycans (HSPGs), syndecan-4 (Sdc4) especially, have been suggested as potential partners of transglutaminase-2 (TG2) i …
Inhibitors of tissue transglutaminase.
Keillor JW, Apperley KY, Akbar A. Keillor JW, et al. Trends Pharmacol Sci. 2015 Jan;36(1):32-40. doi: 10.1016/j.tips.2014.10.014. Epub 2014 Dec 12. Trends Pharmacol Sci. 2015. PMID: 25500711 Review.
Although TG2 is essential for the stabilization of the extracellular matrix, its unregulated activity has been implicated in celiac disease, fibrosis, and cancer metastasis, among other disorders. Given the importance and range of TG2-related pathologies, recent work has f …
Although TG2 is essential for the stabilization of the extracellular matrix, its unregulated activity has been implicated in celiac disease, …
Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer.
Mehta K, Kumar A, Kim HI. Mehta K, et al. Biochem Pharmacol. 2010 Dec 15;80(12):1921-9. doi: 10.1016/j.bcp.2010.06.029. Epub 2010 Jun 25. Biochem Pharmacol. 2010. PMID: 20599779 Review.
Recently, cells that have undergone the epithelial-mesenchymal transition (EMT), which share characteristics with cancer stem cells (CSC) have been implicated to play a role in drug resistance and metastasis of several types of cancer. ...Depending on the cellular c …
Recently, cells that have undergone the epithelial-mesenchymal transition (EMT), which share characteristics with cancer stem cells ( …
Transglutaminase-2: evolution from pedestrian protein to a promising therapeutic target.
Agnihotri N, Mehta K. Agnihotri N, et al. Amino Acids. 2017 Mar;49(3):425-439. doi: 10.1007/s00726-016-2320-2. Epub 2016 Aug 25. Amino Acids. 2017. PMID: 27562794 Review.
The ability of cancer cells to metastasize represents the most devastating feature of cancer. ...TG2-regulated signaling bestows on cancer cells the ability to proliferate, to resist cell death, to invade, to reprogram glucose metabolism and to metastasize, t …
The ability of cancer cells to metastasize represents the most devastating feature of cancer. ...TG2-regulated signaling besto …
Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition.
Ayinde O, Wang Z, Pinton G, Moro L, Griffin M. Ayinde O, et al. Oncotarget. 2019 Jul 16;10(44):4556-4569. doi: 10.18632/oncotarget.27062. eCollection 2019 Jul 16. Oncotarget. 2019. PMID: 31360304 Free PMC article.
Transglutaminase 2 (TG2), a multifunctional protein, is reported in regulating the cancer stem cell (CSC) phenotype in various cancers. Our previous work suggested the link between TG2 and Epithelial-Mesenchymal Transition (EMT) in colorectal cancer (CRC). .. …
Transglutaminase 2 (TG2), a multifunctional protein, is reported in regulating the cancer stem cell (CSC) phenotype in various can
Transglutaminase regulation of cell function.
Eckert RL, Kaartinen MT, Nurminskaya M, Belkin AM, Colak G, Johnson GV, Mehta K. Eckert RL, et al. Physiol Rev. 2014 Apr;94(2):383-417. doi: 10.1152/physrev.00019.2013. Physiol Rev. 2014. PMID: 24692352 Free PMC article. Review.
This review highlights the mechanism of action of these proteins with respect to their structure, impact on cell differentiation and survival, role in cancer development and progression, and function in signal transduction. ...
This review highlights the mechanism of action of these proteins with respect to their structure, impact on cell differentiation and surviva …
Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer.
Lee J, Yakubov B, Ivan C, Jones DR, Caperell-Grant A, Fishel M, Cardenas H, Matei D. Lee J, et al. Neoplasia. 2016 Nov;18(11):689-698. doi: 10.1016/j.neo.2016.09.003. Epub 2016 Oct 25. Neoplasia. 2016. PMID: 27792935 Free PMC article.
Orthotopic pancreatic xenografts and co-culture of PDA and stromal cells were employed to determine the mechanisms by which TG2 alters tumor-stroma interactions and response to gemcitabine. Analysis of the pancreatic The Cancer Genome Atlas (TCGA) database demonstrated tha …
Orthotopic pancreatic xenografts and co-culture of PDA and stromal cells were employed to determine the mechanisms by which TG2 alters tumor …
Phytochemicals and protein-polyamine conjugates by transglutaminase as chemopreventive and chemotherapeutic tools in cancer.
Lentini A, Tabolacci C, Provenzano B, Rossi S, Beninati S. Lentini A, et al. Plant Physiol Biochem. 2010 Jul;48(7):627-33. doi: 10.1016/j.plaphy.2010.02.010. Epub 2010 Feb 23. Plant Physiol Biochem. 2010. PMID: 20227887 Review.
Identifying novel chemopreventive and chemotherapeutic agents and targeting them to patients at high risk of developing cancer or following curative treatment may go some way towards improving prognosis. This review examines current knowledge regarding the chemopreventive …
Identifying novel chemopreventive and chemotherapeutic agents and targeting them to patients at high risk of developing cancer or fol …
564 results