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103 results

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Page 1
Transglutaminase antibodies and celiac disease in children with type 1 diabetes and in their family members.
Parkkola A, Härkönen T, Ryhänen SJ, Uibo R, Ilonen J, Knip M; Finnish Pediatric Diabetes Register. Parkkola A, et al. Pediatr Diabetes. 2018 Mar;19(2):305-313. doi: 10.1111/pedi.12563. Epub 2017 Jul 26. Pediatr Diabetes. 2018. PMID: 28745034
OBJECTIVES: We set out to determine the prevalence of tissue transglutaminase antibodies (anti-tTG) and celiac disease (CD) in children with newly diagnosed type 1 diabetes (T1D) and their first-degree relatives (FDR). The hypothesis was that the individuals with both d
OBJECTIVES: We set out to determine the prevalence of tissue transglutaminase antibodies (anti-tTG) and celiac disease (CD) in children with …
Structural aspects of transglutaminase 2: functional, structural, and regulatory diversity.
Lee CS, Park HH. Lee CS, et al. Apoptosis. 2017 Sep;22(9):1057-1068. doi: 10.1007/s10495-017-1396-9. Apoptosis. 2017. PMID: 28677093 Review.
TG2 is linked to many human diseases such as inflammatory disease, celiac disease, neurodegenerative disease, diabetes, tissue fibrosis, and various cancers and is one of the most dynamic enzymes in terms of its functions, structures, and regulatory mechanisms. ...
TG2 is linked to many human diseases such as inflammatory disease, celiac disease, neurodegenerative disease, diabetes, tissue fibros …
Anti-tissue transglutaminase antibodies (IgA and IgG) in both Crohns disease and autoimmune diabetes.
Ribeiro-Cabral VL, da-Silva-Patrício FR, Ambrogini-Junior O, Jankiel-Miszputen S. Ribeiro-Cabral VL, et al. Rev Esp Enferm Dig. 2011 Sep;103(9):453-7. doi: 10.4321/s1130-01082011000900003. Rev Esp Enferm Dig. 2011. PMID: 21951113 Free article.
RESULTS: anti-transglutaminase antibodies were detected in five diabetic patients (prevalence of 11.1%), only one serum sample was positive for IgG isotypes. ...In Crohns disease, its clinical status and the diagnosis of celiac disease were not associated with positiveanti …
RESULTS: anti-transglutaminase antibodies were detected in five diabetic patients (prevalence of 11.1%), only one serum sample was po …
Transglutaminase 2: an enigmatic enzyme with diverse functions.
Fesus L, Piacentini M. Fesus L, et al. Trends Biochem Sci. 2002 Oct;27(10):534-9. doi: 10.1016/s0968-0004(02)02182-5. Trends Biochem Sci. 2002. PMID: 12368090 Review.
Ablation of TG2 in mice results in impaired wound healing, autoimmunity and diabetes, reflecting the number and variety of TG2 functions. An important role for the enzyme in the pathogenesis of coeliac disease, fibrosis and neurodegenerative disorders has also been demonst …
Ablation of TG2 in mice results in impaired wound healing, autoimmunity and diabetes, reflecting the number and variety of TG2 functi …
New therapeutic approaches to arterial calcification via inhibition of transglutaminase and beta-catenin signaling.
Konoplyannikov M, Nurminskaya M. Konoplyannikov M, et al. Curr Pharm Des. 2014;20(37):5811-20. doi: 10.2174/1381612820666140212205059. Curr Pharm Des. 2014. PMID: 24533936 Review.
Arterial calcification (AC) is a hallmark of many serious diseases, including atherosclerosis, chronic kidney disease, and diabetes. AC may also develop as a side-effect of therapy with anticoagulants, such as warfarin which is widely used for prophylaxis of thrombosis. .. …
Arterial calcification (AC) is a hallmark of many serious diseases, including atherosclerosis, chronic kidney disease, and diabetes. …
Glycolysis regulated transglutaminase 2 activation in cardiopulmonary fibrogenic remodeling.
Bhedi CD, Nasirova S, Toksoz D, Warburton RR, Morine KJ, Kapur NK, Galper JB, Preston IR, Hill NS, Fanburg BL, Penumatsa KC. Bhedi CD, et al. FASEB J. 2020 Jan;34(1):930-944. doi: 10.1096/fj.201902155R. Epub 2019 Nov 28. FASEB J. 2020. PMID: 31914588 Free PMC article.
We examined physiological mouse models of experimental PH, HF, and type 1 diabetes that are associated with altered glucose metabolism/glycolysis and report here that TG2 expression and activity are elevated in pulmonary and cardiac tissues under all these conditions. ...
We examined physiological mouse models of experimental PH, HF, and type 1 diabetes that are associated with altered glucose metabolis …
Type 1 diabetes associated and tissue transglutaminase autoantibodies in patients without type 1 diabetes and coeliac disease with confirmed viral infections.
Sarmiento L, Galvan JA, Cabrera-Rode E, Aira L, Correa C, Sariego S, Fonseca M, Cubas-Dueñas I, Hung LH, Resik S, Cilio CM. Sarmiento L, et al. J Med Virol. 2012 Jul;84(7):1049-53. doi: 10.1002/jmv.23305. J Med Virol. 2012. PMID: 22585721
Coeliac disease and type 1 diabetes are autoimmune diseases that may share the same initiating environmental factors. In this study, the occurrence of type 1 diabetes associated autoantibodies (GADA and IA-2A) and tissue transglutaminase autoantibodies (TGA) was det …
Coeliac disease and type 1 diabetes are autoimmune diseases that may share the same initiating environmental factors. In this study, …
Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases.
Walther DJ, Stahlberg S, Vowinckel J. Walther DJ, et al. FEBS J. 2011 Dec;278(24):4740-55. doi: 10.1111/j.1742-4658.2011.08347.x. Epub 2011 Nov 21. FEBS J. 2011. PMID: 21923757 Free article. Review.
Multiple physiological roles have been identified since its description in 2003 and, importantly, deregulated serotonylation was shown in the etiology of bleeding disorders, primary pulmonary hypertension and diabetes. The PBMAs 5-HT, histamine, dopamine, and norepinephrin …
Multiple physiological roles have been identified since its description in 2003 and, importantly, deregulated serotonylation was shown in th …
Frequency of HLA-DQB1*0201/02 and DQB1*0302 alleles and tissue transglutaminase antibody seropositivity in children with type 1 diabetes mellitus.
Thammarakcharoen T, Hirankarn N, Sahakitrungruang T, Thongmee T, Kuptawintu P, Kanoonthong S, Chongsrisawat V. Thammarakcharoen T, et al. Asian Pac J Allergy Immunol. 2017 Jun;35(2):82-85. doi: 10.12932/AP0751. Asian Pac J Allergy Immunol. 2017. PMID: 27543737 Free article.
BACKGROUND: Patients with type 1 diabetes mellitus (T1DM) have an increased risk of celiac disease (CD). ...METHOD: Forty-six children with T1DM (male:female=24:22; mean age 123.7 years) without significant digestive symptoms were enrolled. The mean duration of d
BACKGROUND: Patients with type 1 diabetes mellitus (T1DM) have an increased risk of celiac disease (CD). ...METHOD: Forty-six …
103 results