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1995 1
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2018 1
2019 1
2020 1
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17 results
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Page 1
Extracellular transglutaminase 2 induces myotube hypertrophy through G protein-coupled receptor 56.
Kitakaze T, Yoshikawa M, Kobayashi Y, Kimura N, Goshima N, Ishikawa T, Ogata Y, Yamashita Y, Ashida H, Harada N, Yamaji R. Kitakaze T, et al. Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118563. doi: 10.1016/j.bbamcr.2019.118563. Epub 2019 Oct 27. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31666191 Free article.
Skeletal muscle secretes biologically active proteins that contribute to muscle hypertrophy in response to either exercise or dietary intake. The identification of skeletal muscle-secreted proteins that induces hypertrophy can provide critical information regarding …
Skeletal muscle secretes biologically active proteins that contribute to muscle hypertrophy in response to either exercise or dietary …
Distinct transglutaminase 2-independent and transglutaminase 2-dependent pathways mediate articular chondrocyte hypertrophy.
Johnson KA, van Etten D, Nanda N, Graham RM, Terkeltaub RA. Johnson KA, et al. J Biol Chem. 2003 May 23;278(21):18824-32. doi: 10.1074/jbc.M301055200. Epub 2003 Feb 26. J Biol Chem. 2003. PMID: 12606540 Free article.
Altered chondrocyte differentiation, including development of chondrocyte hypertrophy, mediates osteoarthritis and pathologic articular cartilage matrix calcification. ...Significantly, TG2 (-/-) chondrocytes lost the capacity for ATRA-induced expression of Cbfa1, a transc …
Altered chondrocyte differentiation, including development of chondrocyte hypertrophy, mediates osteoarthritis and pathologic articul …
Transglutaminase 2 in cartilage homoeostasis: novel links with inflammatory osteoarthritis.
Adamczyk M. Adamczyk M. Amino Acids. 2017 Mar;49(3):625-633. doi: 10.1007/s00726-016-2305-1. Epub 2016 Aug 10. Amino Acids. 2017. PMID: 27510997 Free PMC article. Review.
At the same time, the abnormal accumulation of TG2 in the ECM promotes chondrocyte hypertrophy and cartilage calcification, which might be an important aspect of osteoarthritis (OA) initiation. ...
At the same time, the abnormal accumulation of TG2 in the ECM promotes chondrocyte hypertrophy and cartilage calcification, which mig …
Transglutaminase 2 as a biomarker of osteoarthritis: an update.
Tarantino U, Ferlosio A, Arcuri G, Spagnoli LG, Orlandi A. Tarantino U, et al. Amino Acids. 2013 Jan;44(1):199-207. doi: 10.1007/s00726-011-1181-y. Epub 2011 Dec 3. Amino Acids. 2013. PMID: 22139411 Review.
Under physiologic conditions, articular cartilage displays a stable chondrocyte phenotype, whereas in osteoarthritis a chondrocyte hypertrophy develops near the sites of cartilage surface damage and associates to the pathologic expression of type X collagen. ...
Under physiologic conditions, articular cartilage displays a stable chondrocyte phenotype, whereas in osteoarthritis a chondrocyte hypert
Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes.
Cecil DL, Terkeltaub R. Cecil DL, et al. J Immunol. 2008 Jun 15;180(12):8378-85. doi: 10.4049/jimmunol.180.12.8378. J Immunol. 2008. PMID: 18523305 Free PMC article.
The K3R/Q102N mutant of S100A11 retained the capacity to bind to RAGE and chondrocytes but lost the capacity to signal via the p38 MAPK pathway or induce chondrocyte hypertrophy and glycosaminoglycans release. S100A11 failed to induce hypertrophy, glycosaminoglycan …
The K3R/Q102N mutant of S100A11 retained the capacity to bind to RAGE and chondrocytes but lost the capacity to signal via the p38 MAPK path …
Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA.
Huebner JL, Johnson KA, Kraus VB, Terkeltaub RA. Huebner JL, et al. Osteoarthritis Cartilage. 2009 Aug;17(8):1056-64. doi: 10.1016/j.joca.2009.02.015. Epub 2009 Mar 24. Osteoarthritis Cartilage. 2009. PMID: 19328881 Free PMC article.
Moreover, TG2 knockout suppresses cartilage destruction but promotes osteophyte formation in instability-induced mouse knee osteoarthritis (OA). TG2 is marker of growth plate chondrocyte hypertrophy. Moreover, TG2 secreted by chondrocytes acts in part by promoting chondroc …
Moreover, TG2 knockout suppresses cartilage destruction but promotes osteophyte formation in instability-induced mouse knee osteoarthritis ( …
Role of tissue transglutaminase in age-associated ventricular stiffness.
Oh YJ, Pau VC, Steppan J, Sikka G, Bead VR, Nyhan D, Levine BD, Berkowitz DE, Santhanam L. Oh YJ, et al. Amino Acids. 2017 Mar;49(3):695-704. doi: 10.1007/s00726-016-2295-z. Epub 2016 Jul 20. Amino Acids. 2017. PMID: 27438265
Aging is associated with increased cardiomyocyte loss, left-ventricular hypertrophy, and the accumulation of extracellular matrix, which results in declining cardiac function. ...
Aging is associated with increased cardiomyocyte loss, left-ventricular hypertrophy, and the accumulation of extracellular matrix, wh …
Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement.
Strnad P, Harada M, Siegel M, Terkeltaub RA, Graham RM, Khosla C, Omary MB. Strnad P, et al. Gastroenterology. 2007 Apr;132(4):1515-26. doi: 10.1053/j.gastro.2007.02.020. Epub 2007 Feb 7. Gastroenterology. 2007. PMID: 17408647
The DDC-fed TG2(-/-) mice have dramatic decreases in MB formation and liver hypertrophy response as contrasted with DDC-fed TG2(+/+) mice. Despite similar hepatocellular damage, TG2(-/-) mice had more gallstones, jaundice, and ductal proliferation than wild-type mice. ...
The DDC-fed TG2(-/-) mice have dramatic decreases in MB formation and liver hypertrophy response as contrasted with DDC-fed TG2(+/+) …
Involvement of tissue transglutaminase in endothelin 1-induced hypertrophy in cultured neonatal rat cardiomyocytes.
Li X, Wei XL, Meng LL, Chi MG, Yan JQ, Ma XY, Jia YS, Liang L, Yan HT, Zheng JQ. Li X, et al. Hypertension. 2009 Oct;54(4):839-44. doi: 10.1161/HYPERTENSIONAHA.109.130161. Epub 2009 Jul 27. Hypertension. 2009. PMID: 19635990
A potential link between tissue-type transglutaminase (tTG) and cardiac hypertrophy was suggested recently. However, whether tTG is implicated in hypertrophic agonist-induced cardiac hypertrophy is not yet known. ...Otherwise, ET-1 elevated the activity of GTPase in …
A potential link between tissue-type transglutaminase (tTG) and cardiac hypertrophy was suggested recently. However, whether tTG is i …
17 results