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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1984 1
1989 1
1992 1
1993 2
1994 1
1995 2
1996 1
1997 2
1998 3
1999 2
2000 1
2001 4
2003 5
2004 7
2005 7
2006 13
2007 4
2008 8
2009 11
2010 15
2011 13
2012 12
2013 13
2014 14
2015 13
2016 16
2017 14
2018 11
2019 14
2020 4
2022 0
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178 results
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Page 1
Transglutaminase is a Critical Link Between Inflammation and Hypertension.
Luo R, Liu C, Elliott SE, Wang W, Parchim N, Iriyama T, Daugherty PS, Tao L, Eltzschig HK, Blackwell SC, Sibai BM, Kellems RE, Xia Y. Luo R, et al. J Am Heart Assoc. 2016 Jun 30;5(7):e003730. doi: 10.1161/JAHA.116.003730. J Am Heart Assoc. 2016. PMID: 27364991 Free PMC article.
CONCLUSIONS: Thus, LIGHT-induced hypertension, renal impairment, and production of angiotensin receptor agonistic autoantibodies require TGase, most likely the TG2 isoform. Our findings establish TGase as a critical link between inflammation, hypertension, and autoimmunity …
CONCLUSIONS: Thus, LIGHT-induced hypertension, renal impairment, and production of angiotensin receptor agonistic autoantibodies require TGa …
Tissue transglutaminase, inflammation, and cancer: how intimate is the relationship?
Kumar S, Mehta K. Kumar S, et al. Amino Acids. 2013 Jan;44(1):81-8. doi: 10.1007/s00726-011-1139-0. Epub 2011 Nov 15. Amino Acids. 2013. PMID: 22083892 Review.
It is now well accepted that metastasis and cancer cells' acquired or inherent resistance to conventional therapies are major roadblocks to successful treatment. Chronic inflammation is an important driving force that provides a favorable platform for cancer's progr …
It is now well accepted that metastasis and cancer cells' acquired or inherent resistance to conventional therapies are major roadblocks to …
Transglutaminase 2 and neuroinflammation.
Ientile R, Currò M, Caccamo D. Ientile R, et al. Amino Acids. 2015 Jan;47(1):19-26. doi: 10.1007/s00726-014-1864-2. Epub 2014 Nov 15. Amino Acids. 2015. PMID: 25398223 Review.
The transcription factor NF-kappaB is considered the main regulator of inflammation, being activated by a variety of stimuli including calcium influx, oxidative stress and inflammatory cytokines. ...Several findings emphasize the possible role of the TG2/NF-kappaB activati …
The transcription factor NF-kappaB is considered the main regulator of inflammation, being activated by a variety of stimuli includin …
Is monocyte- and macrophage-derived tissue transglutaminase involved in inflammatory processes?
Chrobok NL, Sestito C, Wilhelmus MM, Drukarch B, van Dam AM. Chrobok NL, et al. Amino Acids. 2017 Mar;49(3):441-452. doi: 10.1007/s00726-016-2334-9. Epub 2016 Sep 22. Amino Acids. 2017. PMID: 27659795 Free PMC article. Review.
In addition, we discuss the role of TG2 in certain pathological conditions, in which inflammation and monocytes and/or macrophages are prominently present, including atherosclerosis, sepsis, and multiple sclerosis. Based on the studies and considerations reported in this r …
In addition, we discuss the role of TG2 in certain pathological conditions, in which inflammation and monocytes and/or macrophages ar …
Transglutaminase 2 in inflammation.
Kim SY. Kim SY. Front Biosci. 2006 Sep 1;11:3026-35. doi: 10.2741/2030. Front Biosci. 2006. PMID: 16720373 Review.
In most cases, TG 2 appears to form an inappropriate protein aggregate that may be cytotoxic enough to trigger inflammation and/or apoptosis. In some cases, such as celiac disease and rheumatoid arthritis, TG 2 is also associated with the pathogenic progression, as well as …
In most cases, TG 2 appears to form an inappropriate protein aggregate that may be cytotoxic enough to trigger inflammation and/or ap …
Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes.
Lai TS, Lin CJ, Greenberg CS. Lai TS, et al. Amino Acids. 2017 Mar;49(3):501-515. doi: 10.1007/s00726-016-2270-8. Epub 2016 Jun 6. Amino Acids. 2017. PMID: 27270573 Review.
Post-translational modification (PTM) is an important mechanism in modulating a protein's structure and can lead to substantial diversity in biological function. ...Many of these substrate proteins play a role in cell signaling, cytoskeleton organization, muscle contractio …
Post-translational modification (PTM) is an important mechanism in modulating a protein's structure and can lead to substantial diver …
Transglutaminase-2: evolution from pedestrian protein to a promising therapeutic target.
Agnihotri N, Mehta K. Agnihotri N, et al. Amino Acids. 2017 Mar;49(3):425-439. doi: 10.1007/s00726-016-2320-2. Epub 2016 Aug 25. Amino Acids. 2017. PMID: 27562794 Review.
Based on the observation that TG2 plays an important role in wound healing and inflammation is known to facilitate cancer growth and progression, we discuss the evidence that TG2 can reprogram inflammatory signaling networks that play fundamental roles in cancer progressio …
Based on the observation that TG2 plays an important role in wound healing and inflammation is known to facilitate cancer growth and …
Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer.
Mehta K, Kumar A, Kim HI. Mehta K, et al. Biochem Pharmacol. 2010 Dec 15;80(12):1921-9. doi: 10.1016/j.bcp.2010.06.029. Epub 2010 Jun 25. Biochem Pharmacol. 2010. PMID: 20599779 Review.
In this review, we discuss the relationship among transglutaminase 2 (TG2), the EMT, and CSCs in inflammation and cancer. TG2 is a structurally and functionally complex protein implicated in such diverse processes as tissue fibrosis, wound healing, apoptosis, neurodegenera …
In this review, we discuss the relationship among transglutaminase 2 (TG2), the EMT, and CSCs in inflammation and cancer. TG2 is a st …
Transglutaminase 2 and Transglutaminase 2 Autoantibodies in Celiac Disease: a Review.
Rauhavirta T, Hietikko M, Salmi T, Lindfors K. Rauhavirta T, et al. Clin Rev Allergy Immunol. 2019 Aug;57(1):23-38. doi: 10.1007/s12016-016-8557-4. Clin Rev Allergy Immunol. 2019. PMID: 27263022 Review.
Celiac disease is a common inflammatory disorder with a prevalence of 1-2 % in which a distinct dietary wheat, rye, and barley component, gluten, induces small-bowel mucosal villous atrophy, crypt hyperplasia, and inflammation. The small-bowel mucosal damage can be reverse …
Celiac disease is a common inflammatory disorder with a prevalence of 1-2 % in which a distinct dietary wheat, rye, and barley component, gl …
178 results