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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1988 1
1989 1
1991 1
1993 1
1994 3
1996 4
1997 1
1998 2
1999 3
2000 1
2001 2
2002 2
2003 2
2004 8
2005 4
2006 9
2007 6
2008 7
2009 8
2010 13
2011 5
2012 4
2013 8
2014 8
2015 6
2016 6
2017 7
2018 9
2019 7
2020 2
2024 0

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128 results

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Page 1
Transglutaminase 2: Friend or foe? The discordant role in neurons and astrocytes.
Quinn BR, Yunes-Medina L, Johnson GVW. Quinn BR, et al. J Neurosci Res. 2018 Jul;96(7):1150-1158. doi: 10.1002/jnr.24239. Epub 2018 Mar 23. J Neurosci Res. 2018. PMID: 29570839 Free PMC article. Review.
TG2 is the most abundant transglutaminase in the central nervous system (CNS) and plays a pivotal role in the CNS injury response. How TG2 affects the cell in response to an insult is strikingly different in astrocytes and neurons. ...In contrast, deletion of TG2 from astr …
TG2 is the most abundant transglutaminase in the central nervous system (CNS) and plays a pivotal role in the CNS injury response. Ho …
Transglutaminase 2 in inflammation.
Kim SY. Kim SY. Front Biosci. 2006 Sep 1;11:3026-35. doi: 10.2741/2030. Front Biosci. 2006. PMID: 16720373 Review.
TG 2 is a crosslinking enzyme that is widely used in many biological systems for tissue stabilization purposes and immediate defense against injury or infection. Aberrant activation of TG 2 activity in tissues contributes to a variety of diseases including neurodegenerativ …
TG 2 is a crosslinking enzyme that is widely used in many biological systems for tissue stabilization purposes and immediate defense against …
The industrial food additive, microbial transglutaminase, mimics tissue transglutaminase and is immunogenic in celiac disease patients.
Matthias T, Jeremias P, Neidhöfer S, Lerner A. Matthias T, et al. Autoimmun Rev. 2016 Dec;15(12):1111-1119. doi: 10.1016/j.autrev.2016.09.011. Epub 2016 Sep 15. Autoimmun Rev. 2016. PMID: 27640315 Review.
Sera were tested by ELISAs, detecting IgA, IgG or both IgA and IgG (check): AESKULISA tTg (tTg), AESKULISA tTg New Generation (tTg neo-epitope (tTg-neo)), microbial transglutaminase (mTg) and mTg neo-epitope (mTg-neo). Marsh criteria were used for the degree of intestinal inju
Sera were tested by ELISAs, detecting IgA, IgG or both IgA and IgG (check): AESKULISA tTg (tTg), AESKULISA tTg New Generation (tTg neo-epito …
Depletion of astrocytic transglutaminase 2 improves injury outcomes.
Monteagudo A, Feola J, Natola H, Ji C, Pröschel C, Johnson GVW. Monteagudo A, et al. Mol Cell Neurosci. 2018 Oct;92:128-136. doi: 10.1016/j.mcn.2018.06.007. Epub 2018 Jun 30. Mol Cell Neurosci. 2018. PMID: 29969654 Free PMC article.
Global deletion of TG2 results in beneficial outcomes subsequent to in vivo ischemic brain injury. Ex vivo studies have also implicated TG2 as a negative regulator of astrocyte viability subsequent to injury. ...Taken together, these data indicate that TG2 plays a p …
Global deletion of TG2 results in beneficial outcomes subsequent to in vivo ischemic brain injury. Ex vivo studies have also implicat …
Transglutaminase 2 in cartilage homoeostasis: novel links with inflammatory osteoarthritis.
Adamczyk M. Adamczyk M. Amino Acids. 2017 Mar;49(3):625-633. doi: 10.1007/s00726-016-2305-1. Epub 2016 Aug 10. Amino Acids. 2017. PMID: 27510997 Free PMC article. Review.
At the same time, the abnormal accumulation of TG2 in the ECM promotes chondrocyte hypertrophy and cartilage calcification, which might be an important aspect of osteoarthritis (OA) initiation. Although excessive joint loading and injuries are one of the main causes leadin …
At the same time, the abnormal accumulation of TG2 in the ECM promotes chondrocyte hypertrophy and cartilage calcification, which might be a …
Tissue transglutaminase in normal and abnormal wound healing: review article.
Verderio EA, Johnson T, Griffin M. Verderio EA, et al. Amino Acids. 2004 Jul;26(4):387-404. doi: 10.1007/s00726-004-0094-4. Epub 2004 Jun 21. Amino Acids. 2004. PMID: 15290345 Review.
A complex series of events involving inflammation, cell migration and proliferation, ECM stabilisation and remodelling, neovascularisation and apoptosis are crucial to the tissue response to injury. Wound healing involves the dynamic interactions of multiple cells types wi …
A complex series of events involving inflammation, cell migration and proliferation, ECM stabilisation and remodelling, neovascularisation a …
Transglutaminase 2 in the balance of cell death and survival.
Fésüs L, Szondy Z. Fésüs L, et al. FEBS Lett. 2005 Jun 13;579(15):3297-302. doi: 10.1016/j.febslet.2005.03.063. Epub 2005 Apr 7. FEBS Lett. 2005. PMID: 15943974 Free article. Review.
In addition, they reveal a further role: the prevention of inflammation, tissue injury and autoimmunity once the apoptosis has already been initiated. ...
In addition, they reveal a further role: the prevention of inflammation, tissue injury and autoimmunity once the apoptosis has alread …
Transglutaminase 2 in neurodegenerative disorders.
Ruan Q, Johnson GV. Ruan Q, et al. Front Biosci. 2007 Jan 1;12:891-904. doi: 10.2741/2111. Front Biosci. 2007. PMID: 17127346 Review.
Most importantly, numerous studies have presented data demonstrating that dysregulation of TG2 may contribute to the pathogenesis of many neurodegenerative disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis as wel …
Most importantly, numerous studies have presented data demonstrating that dysregulation of TG2 may contribute to the pathogenesis of many ne …
Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement.
Strnad P, Harada M, Siegel M, Terkeltaub RA, Graham RM, Khosla C, Omary MB. Strnad P, et al. Gastroenterology. 2007 Apr;132(4):1515-26. doi: 10.1053/j.gastro.2007.02.020. Epub 2007 Feb 7. Gastroenterology. 2007. PMID: 17408647
CONCLUSIONS: We demonstrate an essential role for TG2 in determining injury-mediated liver enlargement and the necessity of K8 and TG2 for generating cross-linked keratins and MBs. ...
CONCLUSIONS: We demonstrate an essential role for TG2 in determining injury-mediated liver enlargement and the necessity of K8 and TG …
128 results