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Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-kappaB activation.
Jambrovics K, Uray IP, Keresztessy Z, Keillor JW, Fésüs L, Balajthy Z. Jambrovics K, et al. Haematologica. 2019 Mar;104(3):505-515. doi: 10.3324/haematol.2018.192823. Epub 2018 Sep 20. Haematologica. 2019. PMID: 30237268 Free PMC article.
Differentiation syndrome (DS) is a life-threatening complication arising during retinoid treatment of acute promyelocytic leukemia (APL). Administration of all-trans retinoic acid leads to significant changes in gene expression, among the most induced of which is transglut …
Differentiation syndrome (DS) is a life-threatening complication arising during retinoid treatment of acute promyelocytic leukemia (A …
Transglutaminase 2 expression in acute myeloid leukemia: association with adhesion molecule expression and leukemic blast motility.
Pierce A, Whetton AD, Meyer S, Ravandi-Kashani F, Borthakur G, Coombes KR, Zhang N, Kornblau S. Pierce A, et al. Proteomics. 2013 Jul;13(14):2216-2224. doi: 10.1002/pmic.201200471. Epub 2013 Jun 6. Proteomics. 2013. PMID: 23576428 Free PMC article.
Acute myeloid leukemia (AML) is a heterogenous disease with differential oncogene association, outcome and treatment regimens. ...
Acute myeloid leukemia (AML) is a heterogenous disease with differential oncogene association, outcome and treatment regimens. ...
Effect of Tissue Transglutaminase on Steroid Resistance in T-Cell Acute Lymphoblastic Leukemia.
Jung HJ, Han EH, Jang IK, Yoon SH, Park JE. Jung HJ, et al. Anticancer Res. 2019 Nov;39(11):6165-6173. doi: 10.21873/anticanres.13824. Anticancer Res. 2019. PMID: 31704844
AIM: To improve survival in patients with glucocorticoid-resistant T-cell acute lymphoblastic leukemia (T-ALL), it is critical to develop new therapeutic strategies to overcome steroid resistance. ...
AIM: To improve survival in patients with glucocorticoid-resistant T-cell acute lymphoblastic leukemia (T-ALL), it is critical to dev …
Analysis of catalytic action of transglutaminase induced in human promyelocytic leukemia (HL-60) and human hepatoblastoma (HepG2) cells.
Ikura K, Shinagawa R, Hatano K, Suto N, Sasaki R. Ikura K, et al. Biosci Biotechnol Biochem. 1996 Oct;60(10):1738-9. doi: 10.1271/bbb.60.1738. Biosci Biotechnol Biochem. 1996. PMID: 8987679 Free article.
Intracellular transglutaminase is induced when human promyelocytic leukemia HL-60 cells are treated with retinoic acid and human hepatoblastoma HepG2 cells, with interleukin-6. ...
Intracellular transglutaminase is induced when human promyelocytic leukemia HL-60 cells are treated with retinoic acid and human hepa …
Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells.
Nagy L, Thomázy VA, Chandraratna RA, Heyman RA, Davies PJ. Nagy L, et al. Leuk Res. 1996 Jun;20(6):499-505. doi: 10.1016/0145-2126(95)00118-2. Leuk Res. 1996. PMID: 8709622
Retinoids induce terminal differentiation and subsequent apoptosis in the human myeloid leukemia (HL-60) cell line. We have previously shown that in HL-60 cells, ligand activation of retinoic acid receptors (RARs) is sufficient to induce differentiation but ligand activati …
Retinoids induce terminal differentiation and subsequent apoptosis in the human myeloid leukemia (HL-60) cell line. We have previousl …
Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.
Li Z, Xu X, Bai L, Chen W, Lin Y. Li Z, et al. J Biol Chem. 2011 Jun 17;286(24):21164-72. doi: 10.1074/jbc.M110.207571. Epub 2011 Apr 27. J Biol Chem. 2011. PMID: 21525012 Free PMC article.
Our previous studies have revealed that acquired tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance in lung cancer cells is associated with Akt-mediated stabilization of cellular caspase 8 and Fas-associated death domain (FADD)-like apoptosis regulator-lik …
Our previous studies have revealed that acquired tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance in lung cancer c …
Effect of microbial transglutaminase cross-linking on the quality characteristics and potential allergenicity of tofu.
Zhu J, Deng H, Yang A, Wu Z, Li X, Tong P, Chen H. Zhu J, et al. Food Funct. 2019 Sep 1;10(9):5485-5497. doi: 10.1039/c9fo01118h. Epub 2019 Aug 14. Food Funct. 2019. PMID: 31411222
A cell sensitization experiment was performed in vitro to evaluate the capability of tofu digestion products to induce the release of bioactive mediators from human basophil leukemia (KU812) cells. Results indicated that MTGase significantly changed the advanced structure …
A cell sensitization experiment was performed in vitro to evaluate the capability of tofu digestion products to induce the release of bioact …
Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions.
Balajthy Z, Csomós K, Vámosi G, Szántó A, Lanotte M, Fésüs L. Balajthy Z, et al. Blood. 2006 Sep 15;108(6):2045-54. doi: 10.1182/blood-2004-02-007948. Epub 2006 Jun 8. Blood. 2006. PMID: 16763214 Free article.
Promyelocytic NB4 leukemia cells undergo differentiation to granulocytes following retinoic acid treatment. ...
Promyelocytic NB4 leukemia cells undergo differentiation to granulocytes following retinoic acid treatment. ...
Induction of GD3/alpha1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cells.
Ha SH, Kang SK, Choi H, Kwak CH, Abekura F, Park JY, Kwon KM, Chang HW, Lee YC, Ha KT, Hou BK, Chung TW, Kim CH. Ha SH, et al. Oncotarget. 2017 Aug 9;8(42):72205-72219. doi: 10.18632/oncotarget.20080. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 29069780 Free PMC article.
The disialic acid-containing glycosphingolipid GD3 recruited membrane transglutaminase 2 (TG2) as a signaling molecule for erythroid differentiation in human chronic myelogenous leukemia (CML) K562 cells. The alpha1-adrenergic receptor (alpha1-AR)/TG2-mediated signaling pa …
The disialic acid-containing glycosphingolipid GD3 recruited membrane transglutaminase 2 (TG2) as a signaling molecule for erythroid differe …
Transglutaminase 2 expression is enhanced synergistically by interferon-gamma and tumour necrosis factor-alpha in human small intestine.
Bayardo M, Punzi F, Bondar C, Chopita N, Chirdo F. Bayardo M, et al. Clin Exp Immunol. 2012 Apr;168(1):95-104. doi: 10.1111/j.1365-2249.2011.04545.x. Clin Exp Immunol. 2012. PMID: 22385244 Free PMC article.
Here we report that IFN-gamma was the most potent inducer of TG2 expression in the small intestinal mucosa and in four [Caco-2, HT-29, Calu-6 and human acute monocytic leukaemia cell line (THP-1)] of five cell lines tested. The combination of TNF-alpha and IFN-gamma produc …
Here we report that IFN-gamma was the most potent inducer of TG2 expression in the small intestinal mucosa and in four [Caco-2, HT-29, Calu- …
36 results