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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1997 2
1998 3
1999 2
2000 5
2001 2
2002 10
2003 6
2004 6
2005 7
2006 10
2007 4
2008 8
2009 10
2010 8
2011 10
2012 9
2013 8
2014 10
2015 5
2016 11
2017 12
2018 8
2019 2
2022 0
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141 results
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[Transglutaminase and neurodegenerative diseases].
Liu Z, Zeng J, Zeng S, Tang B, Wang J. Liu Z, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Aug;32(4):562-6. doi: 10.3760/cma.j.issn.1003-9406.2015.04.025. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015. PMID: 26252108 Review. Chinese.
TGase has been found to contribute to a variety of important physiological and pathological processes and play a role in the pathogenesis of multiple diseases. Notably, neurodegenerative diseases such as Huntington's disease, spinocerebellar ataxia, Alzheimer's disease and …
TGase has been found to contribute to a variety of important physiological and pathological processes and play a role in the pathogenesis of …
New insight into transglutaminase 2 and link to neurodegenerative diseases.
Min B, Chung KC. Min B, et al. BMB Rep. 2018 Jan;51(1):5-13. doi: 10.5483/bmbrep.2018.51.1.227. BMB Rep. 2018. PMID: 29187283 Free PMC article. Review.
Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (NDDs), which include amyotrophic lateral sclerosis (ALS), Alzheimer's, Parkinson's, Huntington's, and prion diseases. ...
Formation of toxic protein aggregates is a common feature and mainly contributes to the pathogenesis of neurodegenerative diseases (N …
Transglutaminase 2 and neuroinflammation.
Ientile R, Currò M, Caccamo D. Ientile R, et al. Amino Acids. 2015 Jan;47(1):19-26. doi: 10.1007/s00726-014-1864-2. Epub 2014 Nov 15. Amino Acids. 2015. PMID: 25398223 Review.
Neuroinflammatory processes seem to play a pivotal role in various chronic neurodegenerative diseases, characterized also by the pathogenetic accumulation of specific protein aggregates. ...Several findings emphasize the possible role of the TG2/NF-kappaB activation pathwa …
Neuroinflammatory processes seem to play a pivotal role in various chronic neurodegenerative diseases, characterized also by the path …
Tissue transglutaminase (TG2) and mitochondrial function and dysfunction.
Lai TS, Lin CJ, Wu YT, Wu CJ. Lai TS, et al. Front Biosci (Landmark Ed). 2017 Mar 1;22(7):1114-1137. doi: 10.2741/4536. Front Biosci (Landmark Ed). 2017. PMID: 28199195 Free article. Review.
Here, we summarize dysfunctional mitochondria in diseases such as in neurodegenerative disorders can modulate TG2's activity and function. TG2 is also important for normal function of mitochondria....
Here, we summarize dysfunctional mitochondria in diseases such as in neurodegenerative disorders can modulate TG2's activity and func …
Transglutaminase is linked to neurodegenerative diseases.
Muma NA. Muma NA. J Neuropathol Exp Neurol. 2007 Apr;66(4):258-63. doi: 10.1097/nen.0b013e31803d3b02. J Neuropathol Exp Neurol. 2007. PMID: 17413316 Review.
Multiple lines of evidence suggest that transglutaminase is involved in neurodegenerative diseases including Alzheimer disease, progressive supranuclear palsy, Huntington disease (HD), and Parkinson disease. ...Lastly, inhibition of transglutaminase either via drug treatme …
Multiple lines of evidence suggest that transglutaminase is involved in neurodegenerative diseases including Alzheimer disease, progr …
Transglutaminase 2: biology, relevance to neurodegenerative diseases and therapeutic implications.
Grosso H, Mouradian MM. Grosso H, et al. Pharmacol Ther. 2012 Mar;133(3):392-410. doi: 10.1016/j.pharmthera.2011.12.003. Epub 2011 Dec 22. Pharmacol Ther. 2012. PMID: 22212614 Review.
Neurodegenerative disorders are characterized by progressive neuronal loss and the aggregation of disease-specific pathogenic proteins in hallmark neuropathologic lesions. ...
Neurodegenerative disorders are characterized by progressive neuronal loss and the aggregation of disease-specific pathogenic protein
Critical role of transglutaminase and other stress proteins during neurodegenerative processes.
Caccamo D, Currò M, Condello S, Ferlazzo N, Ientile R. Caccamo D, et al. Amino Acids. 2010 Feb;38(2):653-8. doi: 10.1007/s00726-009-0428-3. Epub 2009 Dec 5. Amino Acids. 2010. PMID: 19960212 Review.
Proteolytic stress, resulting from the intracellular accumulation of misfolded or aggregated proteins, which exceed the capacity of the ubiquitin-proteasome system to degrade them, plays a relevant role in neurodegenerative disorders, such as Alzheimer's disease, Parkinson …
Proteolytic stress, resulting from the intracellular accumulation of misfolded or aggregated proteins, which exceed the capacity of the ubiq …
Potential of transglutaminase 2 as a therapeutic target.
Caccamo D, Currò M, Ientile R. Caccamo D, et al. Expert Opin Ther Targets. 2010 Sep;14(9):989-1003. doi: 10.1517/14728222.2010.510134. Expert Opin Ther Targets. 2010. PMID: 20670177 Review.
IMPORTANCE OF THE FIELD: Increased expression and activity of transglutaminase 2 - a calcium-dependent enzyme which catalyzes protein cross-linking, polyamination or deamidation at selective glutamine residues - are involved in the etiopathogenesis of several pathological conditi …
IMPORTANCE OF THE FIELD: Increased expression and activity of transglutaminase 2 - a calcium-dependent enzyme which catalyzes protein cross- …
Structural aspects of transglutaminase 2: functional, structural, and regulatory diversity.
Lee CS, Park HH. Lee CS, et al. Apoptosis. 2017 Sep;22(9):1057-1068. doi: 10.1007/s10495-017-1396-9. Apoptosis. 2017. PMID: 28677093 Review.
TG2 is linked to many human diseases such as inflammatory disease, celiac disease, neurodegenerative disease, diabetes, tissue fibrosis, and various cancers and is one of the most dynamic enzymes in terms of its functions, structures, and regulatory mechanisms. ...
TG2 is linked to many human diseases such as inflammatory disease, celiac disease, neurodegenerative disease, diabetes, tissue fibros …
141 results