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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 1
1991 2
1992 1
1993 1
1994 2
1995 1
1996 2
1997 1
1998 1
1999 1
2000 1
2001 2
2002 7
2003 2
2004 8
2005 1
2006 8
2007 8
2008 7
2009 10
2010 15
2011 19
2012 24
2013 16
2014 13
2015 11
2016 10
2017 7
2018 8
2019 9
2020 2
2024 0

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169 results

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Page 1
Transglutaminase type 2 in the regulation of proteostasis.
D'Eletto M, Rossin F, Fedorova O, Farrace MG, Piacentini M. D'Eletto M, et al. Biol Chem. 2019 Jan 28;400(2):125-140. doi: 10.1515/hsz-2018-0217. Biol Chem. 2019. PMID: 29908126 Review.
The maintenance of protein homeostasis (proteostasis) is a fundamental aspect of cell physiology that is essential for the survival of organisms under a variety of environmental and/or intracellular stress conditions. Acute and/or persistent stress exceeding the cap …
The maintenance of protein homeostasis (proteostasis) is a fundamental aspect of cell physiology that is essential for the survival of organ …
Critical role of transglutaminase and other stress proteins during neurodegenerative processes.
Caccamo D, Currò M, Condello S, Ferlazzo N, Ientile R. Caccamo D, et al. Amino Acids. 2010 Feb;38(2):653-8. doi: 10.1007/s00726-009-0428-3. Epub 2009 Dec 5. Amino Acids. 2010. PMID: 19960212 Review.
Proteolytic stress, resulting from the intracellular accumulation of misfolded or aggregated proteins, which exceed the capacity of the ubiquitin-proteasome system to degrade them, plays a relevant role in neurodegenerative disorders, such as Alzheimer's disease, Parkinson …
Proteolytic stress, resulting from the intracellular accumulation of misfolded or aggregated proteins, which exceed the capacity of t …
New insights into the functions and localization of nuclear transglutaminase 2.
Kuo TF, Tatsukawa H, Kojima S. Kuo TF, et al. FEBS J. 2011 Dec;278(24):4756-67. doi: 10.1111/j.1742-4658.2011.08409.x. Epub 2011 Nov 21. FEBS J. 2011. PMID: 22051117 Free article. Review.
Generally, nuclear TG2 represents only 5-7% of the total TG2 in a cell, and various stimuli will increase nuclear TG2 via cellular stress and/or an increased intracellular Ca(2+) concentration. There is increasing evidence indicating the importance of nuclear TG2 in regula …
Generally, nuclear TG2 represents only 5-7% of the total TG2 in a cell, and various stimuli will increase nuclear TG2 via cellular stress
Tissue transglutaminase-mediated chemoresistance in cancer cells.
Verma A, Mehta K. Verma A, et al. Drug Resist Updat. 2007 Aug-Oct;10(4-5):144-51. doi: 10.1016/j.drup.2007.06.002. Epub 2007 Jul 27. Drug Resist Updat. 2007. PMID: 17662645 Review.
This property enables cancer cells not only to grow and survive in stressful environments (metastasis) but also to display resistance against many anticancer agents. ...
This property enables cancer cells not only to grow and survive in stressful environments (metastasis) but also to display resistance …
Efficacy and Safety of Transglutaminase-Induced Corneal Stiffening in Rabbits.
Wu Y, Song W, Tang Y, Elsheikh A, Shao Y, Yan X. Wu Y, et al. Transl Vis Sci Technol. 2019 Dec 12;8(6):27. doi: 10.1167/tvst.8.6.27. eCollection 2019 Nov. Transl Vis Sci Technol. 2019. PMID: 31853423 Free PMC article.
The tangent modulus ratio of Tgases group (1.72 1.0 vs. 1.05 0.22, P = 0.04) was significantly higher than that of UVA/RF under 1.5-MPa stress. The distribution of keratocytes in the corneal stroma and the morphologies of endothelial cells were similar in Tgases CXL-treate …
The tangent modulus ratio of Tgases group (1.72 1.0 vs. 1.05 0.22, P = 0.04) was significantly higher than that of UVA/RF under 1.5-MPa s
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation.
Luciani A, Villella VR, Vasaturo A, Giardino I, Raia V, Pettoello-Mantovani M, D'Apolito M, Guido S, Leal T, Quaratino S, Maiuri L. Luciani A, et al. J Immunol. 2009 Aug 15;183(4):2775-84. doi: 10.4049/jimmunol.0900993. Epub 2009 Jul 22. J Immunol. 2009. PMID: 19625650
CF is characterized by chronic bacterial lung infections and inflammation, and we have previously reported that tissue transglutaminase (TG2), a multifunctional enzyme critical to several diseases, is constitutively up-regulated in CF airways and drives chronic inflammation. Here …
CF is characterized by chronic bacterial lung infections and inflammation, and we have previously reported that tissue transglutaminase (TG2 …
Induction of cross-linking and silencing of Sp1 by transglutaminase during liver injury in ASH and NASH via different ER stress pathways.
Kojima S, Kuo TF, Tatsukawa H, Hirose S. Kojima S, et al. Dig Dis. 2010;28(6):715-21. doi: 10.1159/000324278. Epub 2011 Apr 27. Dig Dis. 2010. PMID: 21525755 Review.
Biochemical analyses on this culture model revealed that both ethanol and FFAs provoked fat accumulation, endoplasmic reticulum (ER) stress, increased nuclear factor-kappaB (NFkappaB) and nuclear TG2, but the synergistic effect was not obvious between FFA and ethanol. ...T …
Biochemical analyses on this culture model revealed that both ethanol and FFAs provoked fat accumulation, endoplasmic reticulum (ER) stre
Transglutaminase as polyamine mediator in plant growth and differentiation.
Aloisi I, Cai G, Serafini-Fracassini D, Del Duca S. Aloisi I, et al. Amino Acids. 2016 Oct;48(10):2467-78. doi: 10.1007/s00726-016-2235-y. Epub 2016 Apr 21. Amino Acids. 2016. PMID: 27101214 Review.
Usually, the TGase activity is present at basal level in plant cells, but it can be induced by internal or external events or stresses, like rehydration, wounding, light, developmental differentiation and programmed cell death (PCD). ...
Usually, the TGase activity is present at basal level in plant cells, but it can be induced by internal or external events or stresses
Transglutaminase 2--a novel inhibitor of adipogenesis.
Myneni VD, Melino G, Kaartinen MT. Myneni VD, et al. Cell Death Dis. 2015 Aug 27;6(8):e1868. doi: 10.1038/cddis.2015.238. Cell Death Dis. 2015. PMID: 26313919 Free PMC article.
TG2 deficiency also resulted in reduced ROCK kinase activity, actin stress fiber formation and increased Akt phosphorylation in MEFs, but did not alter fibronectin matrix levels or solubility. ...
TG2 deficiency also resulted in reduced ROCK kinase activity, actin stress fiber formation and increased Akt phosphorylation in MEFs, …
Senescence and programmed cell death in plants: polyamine action mediated by transglutaminase.
Del Duca S, Serafini-Fracassini D, Cai G. Del Duca S, et al. Front Plant Sci. 2014 Apr 7;5:120. doi: 10.3389/fpls.2014.00120. eCollection 2014. Front Plant Sci. 2014. PMID: 24778637 Free PMC article. Review.
PAs regulate cell division, differentiation, organogenesis, reproduction, dormancy-break and senescence, homeostatic adjustments in response to external stimuli and stresses. Nevertheless, the molecular mechanisms of their multiple activities are still matter of research. …
PAs regulate cell division, differentiation, organogenesis, reproduction, dormancy-break and senescence, homeostatic adjustments in response …
169 results