Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 3
1999 2
2000 2
2001 1
2002 1
2006 1
2008 3
2009 3
2010 2
2011 1
2012 2
2013 3
2014 5
2015 3
2016 2
2017 2
2018 2
2019 4
2020 5
2021 5
2022 4
2023 4
2024 1
2025 2
2026 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

56 results

Results by year

Filters applied: . Clear all
Page 1
CHST3, PGBD5, and SLIT2 can be identified as potential genes for the diagnosis and treatment of osteoporosis and sarcopenia.
Yang X, Du Z, Xing S. Yang X, et al. Sci Rep. 2025 Jan 2;15(1):374. doi: 10.1038/s41598-024-83231-8. Sci Rep. 2025. PMID: 39747879 Free PMC article.
Finally, the CMap database was used to predict potential therapeutic drugs for the diseases, and further validation was conducted through RT-PCR and WB. Three genes for the diseases CHST3, PGBD5, and SLIT2 were identified, showing good predictive performance in both intern …
Finally, the CMap database was used to predict potential therapeutic drugs for the diseases, and further validation was conducted through RT …
Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization.
Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ. Mazany KD, et al. Biochim Biophys Acta. 1998 Jul 1;1407(1):92-7. doi: 10.1016/s0925-4439(98)00028-3. Biochim Biophys Acta. 1998. PMID: 9639683 Free article.
C6ST catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to carbon 6 of the N-acetylgalactosamine residues of chondroitin. ...The human and chick C6ST cDNA share 51% nucleotide identity, 40% amino acyl identity, and 75% amino acyl conservati …
C6ST catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to carbon 6 of the N-acetylgalactosamine residues o …
Recurrent c.776T>C mutation in CHST3 with four other novel mutations and a literature review.
Duz MB, Topak A. Duz MB, et al. Clin Dysmorphol. 2020 Oct;29(4):167-172. doi: 10.1097/MCD.0000000000000329. Clin Dysmorphol. 2020. PMID: 32639237 Review.
Biallelic CHST3 c.776T>C mutations are most frequent mutation in CHST3 and have been reported predominantly in Turkish patients which may be remarkable for genotype-ethnicity correlation in chondrodysplasia with congenital joint dislocations, CHST3 type. I …
Biallelic CHST3 c.776T>C mutations are most frequent mutation in CHST3 and have been reported predominantly in Turkish pati …
Carbohydrate sulfotransferases: a review of emerging diagnostic and prognostic applications.
Begolli G, Marković I, Knežević J, Debeljak Ž. Begolli G, et al. Biochem Med (Zagreb). 2023 Oct 15;33(3):030503. doi: 10.11613/BM.2023.030503. Epub 2023 Aug 5. Biochem Med (Zagreb). 2023. PMID: 37545696 Free PMC article. Review.
The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignancies. Mutations of CHST3 gene cause skeletal dysplasia, chondrodysplasia, and autosomal recessive multiple joint dislocations while inc …
The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignanci …
Indian patients with CHST3-related chondrodysplasia with congenital joint dislocations.
Singh S, Jacob P, Patil SJ, Muranjan M, Shah H, Girisha KM, Bhavani GS. Singh S, et al. Am J Med Genet A. 2024 Mar;194(3):e63422. doi: 10.1002/ajmg.a.63422. Epub 2023 Oct 24. Am J Med Genet A. 2024. PMID: 37876363
CHST3-related chondrodysplasia with congenital joint dislocations (CDCJD, #MIM 143095), is a rare genetic skeletal disorder caused by biallelic loss of function variants in CHST3. ...Genetic testing revealed five homozygous variants in CHST3 (four were novel …
CHST3-related chondrodysplasia with congenital joint dislocations (CDCJD, #MIM 143095), is a rare genetic skeletal disorder caused by …
Chondroitin 6-sulfate represses keratinocyte proliferation in mouse skin, which is associated with psoriasis.
Kitazawa K, Nadanaka S, Kadomatsu K, Kitagawa H. Kitazawa K, et al. Commun Biol. 2021 Jan 25;4(1):114. doi: 10.1038/s42003-020-01618-5. Commun Biol. 2021. PMID: 33495490 Free PMC article.
Here, we report that chondroitin 6-sulfate is important for the maintenance of epidermal homeostasis. Mice deficient in chondroitin 6-O-sulfotransferase-1 (C6st-1), which is involved in biosynthesis of chondroitin 6-sulfate, exhibi …
Here, we report that chondroitin 6-sulfate is important for the maintenance of epidermal homeostasis. Mice deficient in chondroitin …
Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase.
Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O. Fukuta M, et al. J Biol Chem. 1997 Dec 19;272(51):32321-8. doi: 10.1074/jbc.272.51.32321. J Biol Chem. 1997. PMID: 9405439 Free article.
We have previously cloned chondroitin 6-sulfotransferase (C6ST) cDNA from chick embryo chondrocytes. C6ST catalyzes sulfation of chondroitin, keratan sulfate, and sialyl N-acetyllactosamine oligosaccharides. ...This new sulfotransferase cDNA clone was obtained from …
We have previously cloned chondroitin 6-sulfotransferase (C6ST) cDNA from chick embryo chondrocytes. C6ST catalyzes sulfation …
Phenotypic features of carbohydrate sulfotransferase 3 (CHST3) deficiency in 24 patients: congenital dislocations and vertebral changes as principal diagnostic features.
Unger S, Lausch E, Rossi A, Mégarbané A, Sillence D, Alcausin M, Aytes A, Mendoza-Londono R, Nampoothiri S, Afroze B, Hall B, Lo IF, Lam ST, Hoefele J, Rost I, Wakeling E, Mangold E, Godbole K, Vatanavicharn N, Franco LM, Chandler K, Hollander S, Velten T, Reicherter K, Spranger J, Robertson S, Bonafé L, Zabel B, Superti-Furga A. Unger S, et al. Am J Med Genet A. 2010 Oct;152A(10):2543-9. doi: 10.1002/ajmg.a.33641. Am J Med Genet A. 2010. PMID: 20830804
We recently reported on the deficiency of carbohydrate sulfotransferase 3 (CHST3; chondroitin-6-sulfotransferase) in six subjects diagnosed with recessive Larsen syndrome or humero-spinal dysostosis [Hermanns et al. (2008); Am J Hum Genet 82:1368-1374] …
We recently reported on the deficiency of carbohydrate sulfotransferase 3 (CHST3; chondroitin-6-sulfotransferase …
Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth.
Liu J, Chau CH, Liu H, Jang BR, Li X, Chan YS, Shum DK. Liu J, et al. J Cell Sci. 2006 Mar 1;119(Pt 5):933-42. doi: 10.1242/jcs.02796. J Cell Sci. 2006. PMID: 16495484
The differential increase in 6-sulphated chondroitins during axonal growth in both crushed sciatic nerves and brain development suggests that chondroitin 6-sulphotransferase-1 (C6ST-1) is a key enzyme that mediates cell migration in the process. We have clone …
The differential increase in 6-sulphated chondroitins during axonal growth in both crushed sciatic nerves and brain development suggests tha …
Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3.
Zhou Y, Little PJ, Cao Y, Ta HT, Kamato D. Zhou Y, et al. Biochim Biophys Acta Mol Cell Res. 2020 Dec;1867(12):118848. doi: 10.1016/j.bbamcr.2020.118848. Epub 2020 Sep 11. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32920014 Free article.
LPA acting via the LPA receptor 5 (LPAR5) transactivates the TGFBR1 to stimulate the mRNA expression of GAG initiation and elongation genes xylosyltransferase-1 (XYLT1) and chondroitin 6-sulfotransferase-1 (CHST3), respectively. We found that LPA stimulates ROS and Akt sig …
LPA acting via the LPA receptor 5 (LPAR5) transactivates the TGFBR1 to stimulate the mRNA expression of GAG initiation and elongation genes …
56 results