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229 results

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Page 1
Safety and Effectiveness of MiniMed™ 780G Advanced Hybrid Closed-Loop Insulin Intensification in Adults with Insulin-Requiring Type 2 Diabetes.
Bhargava A, Bergenstal RM, Warren ML, Thrasher JR, Dempsey MA, Bode BW, LaRocque J, Carlson AL, Keiter A, Ma H, Shin JJ, McVean JJ, Cordero TL, Rhinehart AS, Vigersky RA; IMPACT2D Study Group. Bhargava A, et al. Diabetes Technol Ther. 2025 Feb 6. doi: 10.1089/dia.2024.0586. Online ahead of print. Diabetes Technol Ther. 2025. PMID: 39912797
Materials and Methods: This 13-site, single-arm, open-label study included 95 adults (mean standard deviation [SD] age of 60.3 10.8 years and T2D duration of 18.6 8.6 years) using basal-bolus insulin therapy. Participants underwent a run-in period (21 days) of open-loop or …
Materials and Methods: This 13-site, single-arm, open-label study included 95 adults (mean standard deviation [SD] age of 60.3 10.8 years an …
The effect of renal function on the clinical outcomes and management of patients hospitalized with hyperglycemic crises.
Almohareb SN, Aljammaz N, Yousif N, Sunbul M, Alsemary R, Alkhathran L, Aldhaeefi M, Almohammed OA, Alshaya AI. Almohareb SN, et al. Front Endocrinol (Lausanne). 2025 Jan 9;15:1445040. doi: 10.3389/fendo.2024.1445040. eCollection 2024. Front Endocrinol (Lausanne). 2025. PMID: 39850482 Free PMC article.
BACKGROUND: The global prevalence of diabetes has been rising rapidly in recent years, leading to an increase in patients experiencing hyperglycemic crises like diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). Patients with impaired ren …
BACKGROUND: The global prevalence of diabetes has been rising rapidly in recent years, leading to an increase in patients experiencing hyper …
Pancreatogenic (Type 3c) Diabetes Revealed by Diabetic Ketoacidosis.
Sivasubramanian D, Prasaanth S, Mani A. Sivasubramanian D, et al. Cureus. 2024 Dec 2;16(12):e74960. doi: 10.7759/cureus.74960. eCollection 2024 Dec. Cureus. 2024. PMID: 39744270 Free PMC article.
This case highlights a 46-year-old male presenting with diabetic ketoacidosis (DKA), a rare but severe complication of type 3c DM. The patient exhibited symptoms of dehydration, metabolic acidosis, and positive urinary ketones, with imaging revealing chronic …
This case highlights a 46-year-old male presenting with diabetic ketoacidosis (DKA), a rare but severe complication of …
Management of diabetic keto-acidosis in adult patients admitted to intensive care unit: an ESICM-endorsed international survey.
Jozwiak M, Hayes MM, Canet E, Lautrette A, Duroyon MM, Molinari N, Jung B. Jozwiak M, et al. Crit Care. 2024 Dec 18;28(1):408. doi: 10.1186/s13054-024-05190-w. Crit Care. 2024. PMID: 39695701 Free PMC article.
BACKGROUND: Guidelines for diabetic ketoacidosis (DKA) management are limited, resulting in varied practices. This study assessed Intensive Care Unit (ICU) admission criteria, fluid resuscitation, insulin therapy, and metabolic management in adult patients wi …
BACKGROUND: Guidelines for diabetic ketoacidosis (DKA) management are limited, resulting in varied practices. This stud …
A nested case-control study of adverse outcomes in children with diabetic ketoacidosis.
Yousif MF, Dolak KD, Adhikari S, White PC. Yousif MF, et al. J Clin Endocrinol Metab. 2024 Dec 6:dgae848. doi: 10.1210/clinem/dgae848. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39657257
BACKGROUND: Adverse Outcomes (death or ICU stays longer than 48h) in children with diabetic ketoacidosis (DKA) or hyperglycemic-hyperosmolar syndrome (HHS) can be predicted by a composite risk score based on severity of hyperglycemia and acidosis, and presenc …
BACKGROUND: Adverse Outcomes (death or ICU stays longer than 48h) in children with diabetic ketoacidosis (DKA) or hyper …
Pembrolizumab-Induced Insulin-Dependent Diabetes Mellitus in a Patient With Triple-Negative Breast Cancer: A Rare Immune-Related Adverse Event.
Tak MB, Munir Z, Aydin A. Tak MB, et al. Cureus. 2024 Nov 5;16(11):e73049. doi: 10.7759/cureus.73049. eCollection 2024 Nov. Cureus. 2024. PMID: 39640141 Free PMC article.
The patient was treated with fluid resuscitation and insulin infusion under the diabetic ketoacidosis (DKA) guidelines of the hospital and was eventually transitioned to a basal-bolus insulin regimen, which was continued after discharge. ...
The patient was treated with fluid resuscitation and insulin infusion under the diabetic ketoacidosis (DKA) guidelines …
Randomized, Crossover Trial of Control-IQ Technology with a Lower Treatment Range and a Modified Meal Bolus Module in Adults, Adolescents, Children, and Preschoolers with Varying Levels of Baseline Glycemic Control.
Brown SA, Laffel LM, Akturk HK, Forlenza GP, Shah VN, Wadwa RP, Cobry EC, Isganaitis E, Schoelwer M, Lu VS, Rueda R, Sherer N, Corbett JP, Sasson-Katchalski R, Pinsker JE. Brown SA, et al. Diabetes Technol Ther. 2024 Nov 26. doi: 10.1089/dia.2024.0501. Online ahead of print. Diabetes Technol Ther. 2024. PMID: 39601043
Results: Overall, 72 participants aged 3-57 years completed the study. There were no diabetic ketoacidosis or severe hypoglycemia events. All meal challenges were completed safely. ...Conclusions: The lower treatment range and late bolus feature of the modifi …
Results: Overall, 72 participants aged 3-57 years completed the study. There were no diabetic ketoacidosis or severe hypoglyce …
Evidence-based obstetric guidance in the setting of a global intravenous fluid shortage.
Heerboth S, Devlin PM, Benipal S, Trawick E, Raghuraman N, Coviello E, Brown EE, Quist-Nelson J. Heerboth S, et al. Am J Obstet Gynecol MFM. 2024 Dec;6(12):101556. doi: 10.1016/j.ajogmf.2024.101556. Epub 2024 Nov 22. Am J Obstet Gynecol MFM. 2024. PMID: 39577770 Review.
We recommend transitioning intravenous (IV) antibiotics to IV push or oral when possible, discontinuing IVF bolus prior to neuraxial anesthesia or for the treatment of preterm labor, and avoiding unnecessary continuous IVF infusions. ...These suggestions for IVF use reduct …
We recommend transitioning intravenous (IV) antibiotics to IV push or oral when possible, discontinuing IVF bolus prior to neuraxial …
Using Quality Improvement to Design and Evaluate an Outpatient Day Treatment Pathway for Pediatric Patients with Diabetes Mellitus Requiring Insulin Initiation.
Azova S, Baskaran C, Einis S, Fortin J, Silva M, Gorman M, Ethier B, Nanavati S, Sterns O, Garvey K, Rhodes ET. Azova S, et al. Pediatr Qual Saf. 2024 Nov 20;9(6):e776. doi: 10.1097/pq9.0000000000000776. eCollection 2024 Nov-Dec. Pediatr Qual Saf. 2024. PMID: 39568636 Free PMC article.
METHODS: A multidisciplinary team identified key initial eligibility criteria for outpatient day treatment for insulin initiation, including absence of diabetic ketoacidosis, age 3 years, and plasma beta-hydroxybutyrate (BOHB) <1 mmol/L. Electronic medical record …
METHODS: A multidisciplinary team identified key initial eligibility criteria for outpatient day treatment for insulin initiation, including …
Secondary diabetes mellitus in acromegaly: Case report and literature review.
Wang J, Zhang Z, Shi Y, Wang W, Hu Y, Chen Z. Wang J, et al. Medicine (Baltimore). 2024 Sep 27;103(39):e39847. doi: 10.1097/MD.0000000000039847. Medicine (Baltimore). 2024. PMID: 39331882 Free PMC article. Review.
PATIENT CONCERNS: A 22-year-old male was hospitalized for diabetic ketoacidosis and exhibited classic signs of acromegaly, such as enlarged hands and feet, and distinct facial changes. ...LESSONS: This case emphasizes the need for comprehensive assessment in patient …
PATIENT CONCERNS: A 22-year-old male was hospitalized for diabetic ketoacidosis and exhibited classic signs of acromegaly, suc …
229 results