Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2019 3
2020 42
2021 28
2022 2
Text availability
Article attribute
Article type
Publication date

Search Results

69 results
Results by year
Filters applied: . Clear all
Page 1
Drug Addiction.
Fluyau D, Charlton TE. Fluyau D, et al. 2021 Sep 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. 2021 Sep 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 31747190 Free Books & Documents. Review.
The layman's definition of addiction is a "fact or condition of being addicted to a particular substance, thing, or activity." Medically it is a "chronic, relapsing disorder characterized by compulsive drug seeking, continued use despite harmful consequence, and long-lasti …
The layman's definition of addiction is a "fact or condition of being addicted to a particular substance, thing, or activity." Medica …
Perinatal Drug Abuse And Neonatal Drug Withdrawal.
Shukla S, Zirkin LB, Gomez Pomar E. Shukla S, et al. 2021 Aug 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. 2021 Aug 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 30085603 Free Books & Documents. Review.
Mechanistic insights into the efficacy of memantine in treating certain drug addictions.
Montemitro C, Angebrandt A, Wang TY, Pettorruso M, Abulseoud OA. Montemitro C, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Dec 20;111:110409. doi: 10.1016/j.pnpbp.2021.110409. Epub 2021 Jul 27. Prog Neuropsychopharmacol Biol Psychiatry. 2021. PMID: 34324921 Free article. Review.
In this review, we summarize preclinical evidences and clinical trials that investigated the efficacy of memantine in treating patients with alcohol, opiate, cocaine, and nicotine use disorders and discuss the results from a mechanistic point of view. Memantine has shown e …
In this review, we summarize preclinical evidences and clinical trials that investigated the efficacy of memantine in treating patients with …
Risk and protective factors of drug abuse among adolescents: a systematic review.
Nawi AM, Ismail R, Ibrahim F, Hassan MR, Manaf MRA, Amit N, Ibrahim N, Shafurdin NS. Nawi AM, et al. BMC Public Health. 2021 Nov 13;21(1):2088. doi: 10.1186/s12889-021-11906-2. BMC Public Health. 2021. PMID: 34774013 Free PMC article.
The familial risk factors were prenatal maternal smoking; poor maternal psychological control; low parental education; negligence; poor supervision; uncontrolled pocket money; and the presence of substance-using family members. One community risk factor reported was having …
The familial risk factors were prenatal maternal smoking; poor maternal psychological control; low parental education; negligence; poor supe …
Covid-19 interface with drug misuse and substance use disorders.
Cisneros IE, Cunningham KA. Cisneros IE, et al. Neuropharmacology. 2021 Oct 15;198:108766. doi: 10.1016/j.neuropharm.2021.108766. Epub 2021 Aug 26. Neuropharmacology. 2021. PMID: 34454912 Free PMC article. Review.
The coronavirus disease 2019 (Covid-19) pandemic intensified the already catastrophic drug overdose and substance use disorder (SUD) epidemic, signaling a syndemic as social isolation, economic and mental health distress, and disrupted treatment services disproportionally …
The coronavirus disease 2019 (Covid-19) pandemic intensified the already catastrophic drug overdose and substance use disorder (SUD) …
Telemedicine and current clinical practice trends in the COVID-19 pandemic.
Wahezi SE, Kohan LR, Spektor B, Brancolini S, Emerick T, Fronterhouse JM, Luedi MM, Colon MA, Kitei PM, Anitescu M, Goeders NE, Patil S, Siddaiah H, Cornett EM, Urman RD, Kaye AD. Wahezi SE, et al. Best Pract Res Clin Anaesthesiol. 2021 Oct;35(3):307-319. doi: 10.1016/j.bpa.2020.11.005. Epub 2020 Nov 16. Best Pract Res Clin Anaesthesiol. 2021. PMID: 34511221 Free PMC article. Review.
Investigating and addressing the immediate and long-term consequences of the COVID-19 pandemic on patients with substance use disorders: a scoping review and evidence map protocol.
Naji L, Dennis B, Morgan RL, Sanger N, Worster A, Paul J, Thabane L, Samaan Z. Naji L, et al. BMJ Open. 2021 Sep 7;11(9):e045946. doi: 10.1136/bmjopen-2020-045946. BMJ Open. 2021. PMID: 34493506 Free PMC article. Review.
We anticipate major consequences resulting from such policies, with marginalised populations expected to bear the greatest burden of such measures, especially those with substance use disorders (SUDs). METHODS AND ANALYSIS: We aim to conduct (1) a scoping review to …
We anticipate major consequences resulting from such policies, with marginalised populations expected to bear the greatest burden of such me …
Yoga for Substance Use: A Systematic Review.
Walia N, Matas J, Turner A, Gonzalez S, Zoorob R. Walia N, et al. J Am Board Fam Med. 2021 Sep-Oct;34(5):964-973. doi: 10.3122/jabfm.2021.05.210175. J Am Board Fam Med. 2021. PMID: 34535521 Free article.
INTRODUCTION: Substance use disorders (SUDs) are complex interactions between various genetic, environmental, developmental, and social factors. ...RESULTS: Among the 8 final studies eligible for quality analysis, 2 had undefined substance use, while the othe …
INTRODUCTION: Substance use disorders (SUDs) are complex interactions between various genetic, environmental, developmental, a …
Addiction treatment in the postpartum period: an opportunity for evidence-based personalized medicine.
Martin CE, Parlier-Ahmad AB. Martin CE, et al. Int Rev Psychiatry. 2021 Sep;33(6):579-590. doi: 10.1080/09540261.2021.1898349. Epub 2021 Jul 8. Int Rev Psychiatry. 2021. PMID: 34238101 Free PMC article. Review.
Substance use disorders (SUD) are becoming rapidly more prevalent in women and a leading cause of pregnancy associated deaths, with most deaths occurring during the 12 months after pregnancy. ...
Substance use disorders (SUD) are becoming rapidly more prevalent in women and a leading cause of pregnancy associated deaths,
Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction.
Saad L, Zwiller J, Kalsbeek A, Anglard P. Saad L, et al. Genes (Basel). 2021 Aug 19;12(8):1263. doi: 10.3390/genes12081263. Genes (Basel). 2021. PMID: 34440437 Free PMC article. Review.
Based on studies describing an increased prevalence of addictive behaviours in several rare sleep disorders and shift workers, a relationship between circadian rhythms and addiction has been hinted for more than a decade. ...Therefore, we think this review may further impr …
Based on studies describing an increased prevalence of addictive behaviours in several rare sleep disorders and shift workers, a rela …
Drug addiction: from bench to bedside.
Cheron J, Kerchove d'Exaerde A. Cheron J, et al. Transl Psychiatry. 2021 Aug 12;11(1):424. doi: 10.1038/s41398-021-01542-0. Transl Psychiatry. 2021. PMID: 34385417 Free PMC article. Review.
Oral Corticosteroids Dependence and Biologic Drugs in Severe Asthma: Myths or Facts? A Systematic Review of Real-World Evidence.
Calzetta L, Aiello M, Frizzelli A, Bertorelli G, Rogliani P, Chetta A. Calzetta L, et al. Int J Mol Sci. 2021 Jul 1;22(13):7132. doi: 10.3390/ijms22137132. Int J Mol Sci. 2021. PMID: 34281184 Free PMC article.
Overall, real-world studies support the evidence that OCS dependence is a real condition that, however, can be found only in a small number of really severe asthmatic patients. In most patients, the dependence on OCS can be related to modifying factors that, when adequatel …
Overall, real-world studies support the evidence that OCS dependence is a real condition that, however, can be found only in a small number …
Epigenetics of Drug Addiction.
Stewart AF, Fulton SL, Maze I. Stewart AF, et al. Cold Spring Harb Perspect Med. 2021 Jul 1;11(7):a040253. doi: 10.1101/cshperspect.a040253. Cold Spring Harb Perspect Med. 2021. PMID: 32513670 Free PMC article. Review.
Substance use disorders (SUDs) are chronic brain diseases characterized by transitions from recreational to compulsive drug use and aberrant drug craving that persists for months to years after abstinence is achieved. ...
Substance use disorders (SUDs) are chronic brain diseases characterized by transitions from recreational to compulsive drug us
The Cocaine and Oxycodone Biobanks, Two Repositories from Genetically Diverse and Behaviorally Characterized Rats for the Study of Addiction.
Carrette LLG, de Guglielmo G, Kallupi M, Maturin L, Brennan M, Boomhower B, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Velarde N, Martinez AR, Kononoff J, Kimbrough A, Simpson S, Smith LC, Shankar K, Ramirez FJ, Chitre AS, Lin B, Polesskaya O, Solberg Woods LC, Palmer AA, George O. Carrette LLG, et al. eNeuro. 2021 Jun 17;8(3):ENEURO.0033-21.2021. doi: 10.1523/ENEURO.0033-21.2021. Print 2021 May-Jun. eNeuro. 2021. PMID: 33875455 Free PMC article. Review.
The rat oxycodone and cocaine biobanks contain samples that vary by genotypes (by using genetically diverse genotyped HS rats), phenotypes (by measuring addiction-like behaviors in an advanced SA model), timepoints (samples are collected longitudinally before, during, and after S …
The rat oxycodone and cocaine biobanks contain samples that vary by genotypes (by using genetically diverse genotyped HS rats), phenotypes ( …
New Approaches in Drug Dependence: Opioids.
Mielau J, Vogel M, Gutwinski S, Mick I. Mielau J, et al. Curr Addict Rep. 2021 May 26:1-8. doi: 10.1007/s40429-021-00373-9. Online ahead of print. Curr Addict Rep. 2021. PMID: 34055568 Free PMC article. Review.
CANUE: A Theoretical Model of Pain as an Antecedent for Substance Use.
Ferguson E, Zale E, Ditre J, Wesolowicz D, Stennett B, Robinson M, Boissoneault J. Ferguson E, et al. Ann Behav Med. 2021 May 6;55(5):489-502. doi: 10.1093/abm/kaaa072. Ann Behav Med. 2021. PMID: 32914834 Free PMC article. Review.
METHODS: An integrative review of current evidence regarding pain, substance use, and associated risk factors (i.e., negative affect, pain-related attitudes, negative urgency, and substance use outcome expectancies) was conducted. RESULTS: The Catastrophizing …
METHODS: An integrative review of current evidence regarding pain, substance use, and associated risk factors (i.e., negative affect, …
Medication overuse and drug addiction: a narrative review from addiction perspective.
Takahashi TT, Ornello R, Quatrosi G, Torrente A, Albanese M, Vigneri S, Guglielmetti M, Maria De Marco C, Dutordoir C, Colangeli E, Fuccaro M, Di Lenola D, Spuntarelli V, Pilati L, Di Marco S, Van Dycke A, Abdullahi RA, Maassen van den Brink A, Martelletti P; European Headache Federation School of Advanced Studies (EHF-SAS). Takahashi TT, et al. J Headache Pain. 2021 Apr 28;22(1):32. doi: 10.1186/s10194-021-01224-8. J Headache Pain. 2021. PMID: 33910499 Free PMC article. Review.
Neural Substrates and Circuits of Drug Addiction.
Feltenstein MW, See RE, Fuchs RA. Feltenstein MW, et al. Cold Spring Harb Perspect Med. 2021 Apr 1;11(4):a039628. doi: 10.1101/cshperspect.a039628. Cold Spring Harb Perspect Med. 2021. PMID: 32205414 Free PMC article. Review.
Prior National Drug Abuse Treatment Clinical Trials Network (CTN) opioid use disorder trials as background and rationale for NIDA CTN-0100 "optimizing retention, duration and discontinuation strategies for opioid use disorder pharmacotherapy (RDD)".
Shulman M, Weiss R, Rotrosen J, Novo P, Costello E, Nunes EV. Shulman M, et al. Addict Sci Clin Pract. 2021 Mar 6;16(1):15. doi: 10.1186/s13722-021-00223-z. Addict Sci Clin Pract. 2021. PMID: 33676577 Free PMC article. Review.
Oxytocin Signaling as a Target to Block Social Defeat-Induced Increases in Drug Abuse Reward.
Ferrer-Pérez C, Reguilón MD, Miñarro J, Rodríguez-Arias M. Ferrer-Pérez C, et al. Int J Mol Sci. 2021 Feb 27;22(5):2372. doi: 10.3390/ijms22052372. Int J Mol Sci. 2021. PMID: 33673448 Free PMC article. Review.
The present review seeks to increase the understanding of the role of OXT in an individual's vulnerability or resilience with regard to developing a substance use disorder. It places specific attention on the role of social stress as a risk factor of addiction, and explore …
The present review seeks to increase the understanding of the role of OXT in an individual's vulnerability or resilience with regard to deve …
Association between supportive interventions and healthcare utilization and outcomes in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a systematic review and meta-analysis.
Deschamps J, Gilbertson J, Straube S, Dong K, MacMaster FP, Korownyk C, Montgomery L, Mahaffey R, Downar J, Clarke H, Muscedere J, Rittenbach K, Featherstone R, Sebastianski M, Vandermeer B, Lynam D, Magnussen R, Bagshaw SM, Rewa OG. Deschamps J, et al. BMC Emerg Med. 2021 Jan 29;21(1):17. doi: 10.1186/s12873-020-00398-9. BMC Emerg Med. 2021. PMID: 33514325 Free PMC article.
We pooled patient and system related outcome data for each supportive strategy. RESULTS: A total of 5664 studies were screened and 19 studies were included. ...CONCLUSION: For patients presenting to acute healthcare settings with complications related to long-term o …
We pooled patient and system related outcome data for each supportive strategy. RESULTS: A total of 5664 studies were screened and 19 …
Impact of Continuing Care on Recovery From Substance Use Disorder.
McKay JR. McKay JR. Alcohol Res. 2021 Jan 21;41(1):01. doi: 10.35946/arcr.v41.1.01. eCollection 2021. Alcohol Res. 2021. PMID: 33500871 Free PMC article. Review.
Continuing care is widely believed to be an important component of effective treatment for substance use disorder, particularly for those individuals with greater problem severity. The purpose of this review was to examine the research literature on continuing care for alc …
Continuing care is widely believed to be an important component of effective treatment for substance use disorder, particularly for t …
Nucleus accumbens as a stereotactic target for the treatment of addictions in humans: a literature review.
Sobstyl M, Kupryjaniuk A, Mierzejewski P. Sobstyl M, et al. Neurol Neurochir Pol. 2021;55(5):440-449. doi: 10.5603/PJNNS.a2021.0065. Epub 2021 Oct 11. Neurol Neurochir Pol. 2021. PMID: 34633060 Free article. Review.
INTRODUCTION: Deep brain stimulation (DBS) has achieved substantial success as a treatment for movement disorders such as Parkinson's Disease (PD), essential tremor (ET), and dystonia. ...Given the ever-expanding understanding of the psychosurgery of addiction, DBS could i …
INTRODUCTION: Deep brain stimulation (DBS) has achieved substantial success as a treatment for movement disorders such as Parkinson's …
Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals.
Galaj E, Xi ZX. Galaj E, et al. Int J Mol Sci. 2020 Dec 24;22(1):134. doi: 10.3390/ijms22010134. Int J Mol Sci. 2020. PMID: 33374481 Free PMC article. Review.
Substance use disorder (SUD) is a serious public health problem worldwide for which available treatments show limited effectiveness. ...
Substance use disorder (SUD) is a serious public health problem worldwide for which available treatments show limited effectiveness.
Endocannabinoid-Like Lipid Neuromodulators in the Regulation of Dopamine Signaling: Relevance for Drug Addiction.
Sagheddu C, Torres LH, Marcourakis T, Pistis M. Sagheddu C, et al. Front Synaptic Neurosci. 2020 Dec 23;12:588660. doi: 10.3389/fnsyn.2020.588660. eCollection 2020. Front Synaptic Neurosci. 2020. PMID: 33424577 Free PMC article. Review.
These molecules exert a variety of biological activities in the central nervous system, as they modulate physiological processes in neurons and glial cells and are involved in the pathophysiology of neurological and psychiatric disorders. Their effects on dopamine cells ha …
These molecules exert a variety of biological activities in the central nervous system, as they modulate physiological processes in neurons …
Current Evidence on Abuse and Misuse of Gabapentinoids.
Hägg S, Jönsson AK, Ahlner J. Hägg S, et al. Drug Saf. 2020 Dec;43(12):1235-1254. doi: 10.1007/s40264-020-00985-6. Drug Saf. 2020. PMID: 32857333 Free PMC article. Review.
Studies found that gabapentinoids are abused and misused and that individuals with a history of psychiatric disorders or substance use disorder seem to be at high risk. Moreover, some evidence supports the notion that patients with opioid use disorders may be …
Studies found that gabapentinoids are abused and misused and that individuals with a history of psychiatric disorders or substance
The role of restraint in fatal excited delirium: a research synthesis and pooled analysis.
Strömmer EMF, Leith W, Zeegers MP, Freeman MD. Strömmer EMF, et al. Forensic Sci Med Pathol. 2020 Dec;16(4):680-692. doi: 10.1007/s12024-020-00291-8. Epub 2020 Aug 22. Forensic Sci Med Pathol. 2020. PMID: 32827300 Free PMC article. Review.
These findings are at odds with previously published theories indicating that ExDS-related death is due to an occult pathophysiologic process. When death has occurred in an aggressively restrained individual who fits the profile of either ExDS or AgDS, restraint-related
These findings are at odds with previously published theories indicating that ExDS-related death is due to an occult pathophysiologic …
Hispanic participants in the National Institute on Drug Abuse's Clinical Trials Network: A scoping review of two decades of research.
Eghaneyan BH, Sanchez K, Haeny AM, Montgomery L, Lopez-Castro T, Burlew AK, Rezaeizadeh A, Killian MO. Eghaneyan BH, et al. Addict Behav Rep. 2020 Jun 1;12:100287. doi: 10.1016/j.abrep.2020.100287. eCollection 2020 Dec. Addict Behav Rep. 2020. PMID: 32637563 Free PMC article. Review.
INTRODUCTION: Hispanics significantly underutilize substance abuse treatment and are at greater risk for poor treatment outcomes and dropout. ...Results identified issues in measurement, characteristics of Hispanic substance use, effective interventions, and gaps fo …
INTRODUCTION: Hispanics significantly underutilize substance abuse treatment and are at greater risk for poor treatment outcomes and …
HIV Infection and Neurocognitive Disorders in the Context of Chronic Drug Abuse: Evidence for Divergent Findings Dependent upon Prior Drug History.
Illenberger JM, Harrod SB, Mactutus CF, McLaurin KA, Kallianpur A, Booze RM. Illenberger JM, et al. J Neuroimmune Pharmacol. 2020 Dec;15(4):715-728. doi: 10.1007/s11481-020-09928-5. Epub 2020 Jun 12. J Neuroimmune Pharmacol. 2020. PMID: 32533296 Free PMC article. Review.
Similarly, chronic exposure to HIV-1, even with combination antiretroviral therapy (cART), dysregulates dopamine and dopamine transporter function and alters connectivity of the fronto-striatal circuit, contributing to apathy and clinical symptoms of HIV-1 associated neurocogniti …
Similarly, chronic exposure to HIV-1, even with combination antiretroviral therapy (cART), dysregulates dopamine and dopamine transporter fu …
Toll-Like Receptor 4 Signaling and Drug Addiction.
Wu R, Li JX. Wu R, et al. Front Pharmacol. 2020 Nov 24;11:603445. doi: 10.3389/fphar.2020.603445. eCollection 2020. Front Pharmacol. 2020. PMID: 33424612 Free PMC article. Review.
Inhibition of TLR4 or its downstream effectors attenuated the reinforcing effects of opioids, alcohol and psychostimulants, and this effect is also involved in the withdrawal and relapse-like behaviors of different drug classes. However, conflicting results also argue that TLR4- …
Inhibition of TLR4 or its downstream effectors attenuated the reinforcing effects of opioids, alcohol and psychostimulants, and this effect …
Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: Review of modalities and implications for treatment.
Mahoney JJ 3rd, Hanlon CA, Marshalek PJ, Rezai AR, Krinke L. Mahoney JJ 3rd, et al. J Neurol Sci. 2020 Nov 15;418:117149. doi: 10.1016/j.jns.2020.117149. Epub 2020 Sep 20. J Neurol Sci. 2020. PMID: 33002757 Free PMC article. Review.
One such approach involves neuromodulation which has been used therapeutically for neurological and psychiatric disorders and has demonstrated positive preliminary findings for the treatment of substance use disorder. ...Search criteria for Addiction included the fo …
One such approach involves neuromodulation which has been used therapeutically for neurological and psychiatric disorders and has dem …
Preventing HIV outbreaks among people who inject drugs in the United States: plus ça change, plus ça même chose.
Strathdee SA, Kuo I, El-Bassel N, Hodder S, Smith LR, Springer SA. Strathdee SA, et al. AIDS. 2020 Nov 15;34(14):1997-2005. doi: 10.1097/QAD.0000000000002673. AIDS. 2020. PMID: 32826391 Free PMC article. Review.
Restructuring a path forward requires that evidence-based interventions be integrated and brought to scale while simultaneously addressing underlying structural drivers of HIV and related syndemics. Failing to do so will mean that HIV outbreaks among PWID and the communiti …
Restructuring a path forward requires that evidence-based interventions be integrated and brought to scale while simultaneously addressing u …
Risk Management in First Aid for Acute Drug Intoxication.
Piccioni A, Cicchinelli S, Saviano L, Gilardi E, Zanza C, Brigida M, Tullo G, Volonnino G, Covino M, Franceschi F, La Russa R. Piccioni A, et al. Int J Environ Res Public Health. 2020 Oct 30;17(21):8021. doi: 10.3390/ijerph17218021. Int J Environ Res Public Health. 2020. PMID: 33143348 Free PMC article.
In 2017, 34.2% of students reported having used an illegal psychoactive substance in their lifetime, while 26% reported having done so over the past year. ...
In 2017, 34.2% of students reported having used an illegal psychoactive substance in their lifetime, while 26% reported having done s …
Roles of Pharmacy Technicians in Preventing Prescription Drug Abuse.
Geise R, Powers MF. Geise R, et al. J Pharm Technol. 2020 Oct;36(5):211-217. doi: 10.1177/8755122520939640. Epub 2020 Jul 13. J Pharm Technol. 2020. PMID: 34752547 Free PMC article. Review.
Objective: To provide and identify potential roles and strategies for pharmacy technicians to identify and prevent drug abuse within the pharmacy. Data Sources: Related materials were searched via PubMed and Google Scholar from 2000 to present using search terms: "pharmacy …
Objective: To provide and identify potential roles and strategies for pharmacy technicians to identify and prevent drug abuse within the pha …
Oxidative Stress and Neuroinflammation as a Pivot in Drug Abuse. A Focus on the Therapeutic Potential of Antioxidant and Anti-Inflammatory Agents and Biomolecules.
Berríos-Cárcamo P, Quezada M, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Berríos-Cárcamo P, et al. Antioxidants (Basel). 2020 Sep 4;9(9):830. doi: 10.3390/antiox9090830. Antioxidants (Basel). 2020. PMID: 32899889 Free PMC article. Review.
This effect consolidates the relapse-promoting effect of drug-related cues, thus sustaining drug craving and subsequent drug consumption. ...
This effect consolidates the relapse-promoting effect of drug-related cues, thus sustaining drug craving and subsequent drug consumpt …
Unpredictability as a modulator of drug self-administration: Relevance for substance-use disorders.
Huskinson SL. Huskinson SL. Behav Processes. 2020 Sep;178:104156. doi: 10.1016/j.beproc.2020.104156. Epub 2020 Jun 8. Behav Processes. 2020. PMID: 32526314 Free PMC article. Review.
Drug self-administration has been regarded as a gold-standard preclinical model of addiction and substance-use disorder (SUD). However, investigators are becoming increasingly aware, that certain aspects of addiction or SUDs experienced by humans are not accurately capture …
Drug self-administration has been regarded as a gold-standard preclinical model of addiction and substance-use disorder (SUD). Howeve …
Role of Inflammasomes in HIV-1 and Drug Abuse Mediated Neuroinflammaging.
Sil S, Niu F, Chivero ET, Singh S, Periyasamy P, Buch S. Sil S, et al. Cells. 2020 Aug 8;9(8):1857. doi: 10.3390/cells9081857. Cells. 2020. PMID: 32784383 Free PMC article. Review.
It is also estimated that ~30-60% of PLWH on cART develop cognitive deficits associated with HIV-1-associated neurocognitive disorders (HAND), with symptomatology ranging from asymptomatic to mild, neurocognitive impairments. ...
It is also estimated that ~30-60% of PLWH on cART develop cognitive deficits associated with HIV-1-associated neurocognitive disorders
Consensus Guidelines and State Policies: The Gap Between Principle and Practice at the Intersection of Substance Use and Pregnancy.
Faherty LJ, Stein BD, Terplan M. Faherty LJ, et al. Am J Obstet Gynecol MFM. 2020 Aug;2(3):100137. doi: 10.1016/j.ajogmf.2020.100137. Epub 2020 May 17. Am J Obstet Gynecol MFM. 2020. PMID: 33089133 Free PMC article. Review.
The opioid crisis has had a substantial effect on women who are pregnant and parenting, focusing both public health and policymaker attention on opioids and on other substance use in pregnancy and postpartum. There is overwhelming consensus on the principle of a non-puniti …
The opioid crisis has had a substantial effect on women who are pregnant and parenting, focusing both public health and policymaker attentio …
Caring for patients with lived experience of homelessness.
Andermann A, Bloch G, Goel R, Brcic V, Salvalaggio G, Twan S, Kendall CE, Ponka D, Pottie K. Andermann A, et al. Can Fam Physician. 2020 Aug;66(8):563-570. Can Fam Physician. 2020. PMID: 32817028 Free PMC article. Review.
MAIN MESSAGE: Family physicians can use simple and effective approaches to identify patients who are homeless or vulnerably housed; take initial steps to initiate access to housing, income assistance, case management, and treatment for substance use; and work collaborative …
MAIN MESSAGE: Family physicians can use simple and effective approaches to identify patients who are homeless or vulnerably housed; take ini …
Underlying Susceptibility to Eating Disorders and Drug Abuse: Genetic and Pharmacological Aspects of Dopamine D4 Receptors.
Botticelli L, Micioni Di Bonaventura E, Del Bello F, Giorgioni G, Piergentili A, Romano A, Quaglia W, Cifani C, Micioni Di Bonaventura MV. Botticelli L, et al. Nutrients. 2020 Jul 30;12(8):2288. doi: 10.3390/nu12082288. Nutrients. 2020. PMID: 32751662 Free PMC article. Review.
The dopamine D4 receptor (DRD4) has a predominant expression in the prefrontal cortex (PFC), brain area strictly involved in the modulation of reward processes related to both food and drug consumption. Additionally, the human DRD4 gene is characterized by a variable numbe …
The dopamine D4 receptor (DRD4) has a predominant expression in the prefrontal cortex (PFC), brain area strictly involved in the modulation …
Mindfulness-based programs for substance use disorders: a systematic review of manualized treatments.
Korecki JR, Schwebel FJ, Votaw VR, Witkiewitz K. Korecki JR, et al. Subst Abuse Treat Prev Policy. 2020 Jul 29;15(1):51. doi: 10.1186/s13011-020-00293-3. Subst Abuse Treat Prev Policy. 2020. PMID: 32727559 Free PMC article.
BACKGROUND: Substance use disorders are prevalent and returning to substance use (i.e., relapse) following treatment is common, underscoring the need for effective treatments that will help individuals maintain long-term reductions in substance use. .. …
BACKGROUND: Substance use disorders are prevalent and returning to substance use (i.e., relapse) following treatment is …
Addictovigilance contribution during COVID-19 epidemic and lockdown in France.
Lapeyre-Mestre M, Boucher A, Daveluy A, Gibaja V, Jouanjus E, Mallaret M, Peyrière H, Micallef J; French Addictovigilance Network. Lapeyre-Mestre M, et al. Therapie. 2020 Jul-Aug;75(4):343-354. doi: 10.1016/j.therap.2020.06.006. Epub 2020 Jun 23. Therapie. 2020. PMID: 32660776 Free PMC article. Review.
As soon as the lockdown began, first cases of overdoses (lethal or not) were reported with opioids, mainly with methadone, and other opioids (heroin, oxycodone, tramadol or antitussive codeine). Lockdown-related noteworthy events consisted in clinical cases or other releva …
As soon as the lockdown began, first cases of overdoses (lethal or not) were reported with opioids, mainly with methadone, and other opioids …
Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models.
Müller TE, Fontana BD, Bertoncello KT, Franscescon F, Mezzomo NJ, Canzian J, Stefanello FV, Parker MO, Gerlai R, Rosemberg DB. Müller TE, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Jun 8;100:109873. doi: 10.1016/j.pnpbp.2020.109873. Epub 2020 Jan 22. Prog Neuropsychopharmacol Biol Psychiatry. 2020. PMID: 31981718 Free article. Review.
Drug abuse and brain disorders related to drug comsumption are public health problems with harmful individual and social consequences. ...In this review, we discuss how the zebrafish has been successfully used for modeling neurobehavioral phenotypes related t …
Drug abuse and brain disorders related to drug comsumption are public health problems with harmful individual and social conse …
Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders: A Systematic Review and Meta-analysis.
Ray LA, Meredith LR, Kiluk BD, Walthers J, Carroll KM, Magill M. Ray LA, et al. JAMA Netw Open. 2020 Jun 1;3(6):e208279. doi: 10.1001/jamanetworkopen.2020.8279. JAMA Netw Open. 2020. PMID: 32558914 Free PMC article.
IMPORTANCE: Substance use disorders (SUDs) represent a pressing public health concern. ...Sensitivity analyses included assessment of study quality, pooled effect size heterogeneity, publication bias, and primary substance moderator effects. MAIN OUTCOMES AND …
IMPORTANCE: Substance use disorders (SUDs) represent a pressing public health concern. ...Sensitivity analyses included assess …
Clinician Wellness During the COVID-19 Pandemic: Extraordinary Times and Unusual Challenges for the Allergist/Immunologist.
Bansal P, Bingemann TA, Greenhawt M, Mosnaim G, Nanda A, Oppenheimer J, Sharma H, Stukus D, Shaker M. Bansal P, et al. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1781-1790.e3. doi: 10.1016/j.jaip.2020.04.001. Epub 2020 Apr 4. J Allergy Clin Immunol Pract. 2020. PMID: 32259628 Free PMC article. Review.
Clinicians can leverage easily accessible tools, including the Strength-Focused and Meaning-Oriented Approach to Resilience and Transformation approach, wellness apps, mindfulness, and gratitude. Realizing early warning signs of anxiety, depression, substance abuse, and po …
Clinicians can leverage easily accessible tools, including the Strength-Focused and Meaning-Oriented Approach to Resilience and Transformati …
The role of oxytocin in alcohol and drug abuse.
King CE, Gano A, Becker HC. King CE, et al. Brain Res. 2020 Jun 1;1736:146761. doi: 10.1016/j.brainres.2020.146761. Epub 2020 Mar 3. Brain Res. 2020. PMID: 32142721 Free PMC article. Review.
Through interactions with brain reward and stress systems, OXT is known to play a role in several neuropsychiatric disorders, particularly those that involve altered social integration, such as alcohol and drug addiction (Heilig et al., 2016). As such, there is growing int …
Through interactions with brain reward and stress systems, OXT is known to play a role in several neuropsychiatric disorders, particu …
Frequency of health-care utilization by adults who use illicit drugs: a systematic review and meta-analysis.
Lewer D, Freer J, King E, Larney S, Degenhardt L, Tweed EJ, Hope VD, Harris M, Millar T, Hayward A, Ciccarone D, Morley KI. Lewer D, et al. Addiction. 2020 Jun;115(6):1011-1023. doi: 10.1111/add.14892. Epub 2020 Feb 10. Addiction. 2020. PMID: 31705770 Free PMC article.
SETTING AND PARTICIPANTS: People who use heroin, powder cocaine, crack cocaine, methamphetamine, amphetamine, ecstasy/3,4-methylenedioxymethamphetamine (MDMA), cannabis, hallucinogens or novel psychoactive substances; have a diagnosis of 'substance use disorder'; or use dr …
SETTING AND PARTICIPANTS: People who use heroin, powder cocaine, crack cocaine, methamphetamine, amphetamine, ecstasy/3,4-methylenedioxymeth …
Alcohol Use and Antiretroviral Therapy Non-Adherence Among Adults Living with HIV/AIDS in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.
Velloza J, Kemp CG, Aunon FM, Ramaiya MK, Creegan E, Simoni JM. Velloza J, et al. AIDS Behav. 2020 Jun;24(6):1727-1742. doi: 10.1007/s10461-019-02716-0. AIDS Behav. 2020. PMID: 31673913 Free PMC article.
We searched PubMed, CINAHL, EMBASE, and PsycINFO through August 2019 with terms related to ART non-adherence, alcohol use, and sub-Saharan Africa. ...
We searched PubMed, CINAHL, EMBASE, and PsycINFO through August 2019 with terms related to ART non-adherence, alcohol use, and sub-Sa …
The effect of tai chi and Qigong exercise on depression and anxiety of individuals with substance use disorders: a systematic review and meta-analysis.
Liu F, Cui J, Liu X, Chen KW, Chen X, Li R. Liu F, et al. BMC Complement Med Ther. 2020 May 29;20(1):161. doi: 10.1186/s12906-020-02967-8. BMC Complement Med Ther. 2020. PMID: 32471415 Free PMC article.
However, there is a scarcity of systematic reviews summarizing the clinical evidence conducted among individuals with substance use disorders. This study tries to fill up this gap. METHODS: A systematic search using Medline, EMbase, PsychINFO, Eric, SPORTDiscus, CIN …
However, there is a scarcity of systematic reviews summarizing the clinical evidence conducted among individuals with substance use …
Pharmacotherapeutic management of co-morbid alcohol and opioid use.
Hood LE, Leyrer-Jackson JM, Olive MF. Hood LE, et al. Expert Opin Pharmacother. 2020 May;21(7):823-839. doi: 10.1080/14656566.2020.1732349. Epub 2020 Feb 27. Expert Opin Pharmacother. 2020. PMID: 32103695 Free PMC article. Review.
Opioid use disorder (OUD) and alcohol use disorder (AUD) are two highly prevalent substance-related disorders worldwide. Co-use of the substances is also quite prevalent, yet there are no pharmacological treatment approaches specifically designed to treat co- …
Opioid use disorder (OUD) and alcohol use disorder (AUD) are two highly prevalent substance-related disorders worldwide …
The effectiveness of case management interventions for the homeless, vulnerably housed and persons with lived experience: A systematic review.
Ponka D, Agbata E, Kendall C, Stergiopoulos V, Mendonca O, Magwood O, Saad A, Larson B, Sun AH, Arya N, Hannigan T, Thavorn K, Andermann A, Tugwell P, Pottie K. Ponka D, et al. PLoS One. 2020 Apr 9;15(4):e0230896. doi: 10.1371/journal.pone.0230896. eCollection 2020. PLoS One. 2020. PMID: 32271769 Free PMC article.
We sought outcomes on housing stability, mental health, quality of life, substance use, hospitalization, income and employment, and cost-effectiveness. ...Standard case management had both limited and short-term effects on substance use and housing outcomes and show …
We sought outcomes on housing stability, mental health, quality of life, substance use, hospitalization, income and employment, and c …
Study Characteristics Influence the Efficacy of Substance Abuse Treatments: A Meta-analysis of Medications for Smoking Cessation.
Klemperer EM, Hughes JR, Naud S. Klemperer EM, et al. Nicotine Tob Res. 2020 Mar 16;22(3):317-323. doi: 10.1093/ntr/nty225. Nicotine Tob Res. 2020. PMID: 30380134 Free PMC article. Review.
We encourage researchers to report study characteristics to improve interpretation of findings and systematic reviews, and to account for nontreatment-related variables to better estimate the efficacy of treatments....
We encourage researchers to report study characteristics to improve interpretation of findings and systematic reviews, and to account for no …
Smoke, alcohol and drug addiction and female fertility.
de Angelis C, Nardone A, Garifalos F, Pivonello C, Sansone A, Conforti A, Di Dato C, Sirico F, Alviggi C, Isidori A, Colao A, Pivonello R. de Angelis C, et al. Reprod Biol Endocrinol. 2020 Mar 12;18(1):21. doi: 10.1186/s12958-020-0567-7. Reprod Biol Endocrinol. 2020. PMID: 32164734 Free PMC article. Review.
Polypharmacy in HIV: recent insights and future directions.
Edelman EJ, Rentsch CT, Justice AC. Edelman EJ, et al. Curr Opin HIV AIDS. 2020 Mar;15(2):126-133. doi: 10.1097/COH.0000000000000608. Curr Opin HIV AIDS. 2020. PMID: 31833963 Free PMC article. Review.
As sicker individuals take more medications, analyses must account for severity of illness. As self-report of substance use may be inaccurate, direct biomarkers, such as phosphatidylethanol (PEth) for alcohol are needed. Large samples including electronic health records, g …
As sicker individuals take more medications, analyses must account for severity of illness. As self-report of substance use may be in …
Abuse potential and toxicity of the synthetic cathinones (i.e., "Bath salts").
Riley AL, Nelson KH, To P, López-Arnau R, Xu P, Wang D, Wang Y, Shen HW, Kuhn DM, Angoa-Perez M, Anneken JH, Muskiewicz D, Hall FS. Riley AL, et al. Neurosci Biobehav Rev. 2020 Mar;110:150-173. doi: 10.1016/j.neubiorev.2018.07.015. Epub 2019 May 14. Neurosci Biobehav Rev. 2020. PMID: 31101438 Free PMC article. Review.
Pain in persons who are marginalized by social conditions.
Craig KD, Holmes C, Hudspith M, Moor G, Moosa-Mitha M, Varcoe C, Wallace B. Craig KD, et al. Pain. 2020 Feb;161(2):261-265. doi: 10.1097/j.pain.0000000000001719. Pain. 2020. PMID: 31651578 Free PMC article. Review. No abstract available.
Managing Pain in the Setting of Opioid Use Disorder.
St Marie B, Broglio K. St Marie B, et al. Pain Manag Nurs. 2020 Feb;21(1):26-34. doi: 10.1016/j.pmn.2019.08.003. Epub 2019 Oct 21. Pain Manag Nurs. 2020. PMID: 31648905 Free PMC article. Review.
A systematic scoping review of research on Black participants in the National Drug Abuse Treatment Clinical Trials Network.
Montgomery L, Burlew AK, Haeny AM, Jones CA. Montgomery L, et al. Psychol Addict Behav. 2020 Feb;34(1):117-127. doi: 10.1037/adb0000483. Epub 2019 Jun 27. Psychol Addict Behav. 2020. PMID: 31246072 Free PMC article.
Black individuals experience a disproportionate burden of substance-related disabilities and premature death relative to other racial/ethnic groups, highlighting the need for additional research. The National Drug Abuse Treatment Clinical Trials Network (CTN), a res …
Black individuals experience a disproportionate burden of substance-related disabilities and premature death relative to other …