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Myeloid/lymphoid neoplasms with FLT3 rearrangement.
Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA. Tang G, et al. Mod Pathol. 2021 Sep;34(9):1673-1685. doi: 10.1038/s41379-021-00817-7. Epub 2021 May 14. Mod Pathol. 2021. PMID: 33990705 Free article.
We report 12 patients with confirmed FLT3 rearrangement, six with t(12;13)/ETV6-FLT3; one with ins(13;22)/BCR-FLT3; and five with an unconfirmed partner gene located on chromosome bands 2p16, 3q27, 5q15, 5q35, and 7q36. ...Eleven patients received disease-based chem …
We report 12 patients with confirmed FLT3 rearrangement, six with t(12;13)/ETV6-FLT3; one with ins(13;22)/BCR-FLT3; and five w …
Myeloid/lymphoid neoplasms with eosinophilia and FLT3 rearrangement.
Shao H, Wang W, Song J, Tang G, Zhang X, Tang Z, Srivastava J, Shah B, Medeiros LJ, Zhang L. Shao H, et al. Leuk Res. 2020 Dec;99:106460. doi: 10.1016/j.leukres.2020.106460. Epub 2020 Oct 6. Leuk Res. 2020. PMID: 33166908 Review.
Unfortunately, the patient showed persistent residual disease and passed away 9 months after the diagnosis from pneumonia. The other two cases both showed ETV6-FLT3. The second patient was treated with local radiation and systemic chemotherapy including sorafenib an …
Unfortunately, the patient showed persistent residual disease and passed away 9 months after the diagnosis from pneumonia. The other two cas …
T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature.
Schoelinck J, Gervasoni J, Guillermin Y, Beillard E, Pissaloux D, Chassagne-Clement C. Schoelinck J, et al. Virchows Arch. 2024 May;484(5):853-857. doi: 10.1007/s00428-023-03693-5. Epub 2023 Nov 20. Virchows Arch. 2024. PMID: 37985498 Review.
Here, we report a very unusual case of myeloid/lymphoid neoplasm with ETV6::FLT3 fusion with a nodal presentation without associated eosinophilia. Our case draws attention to diagnostic pitfalls in these rare entities....
Here, we report a very unusual case of myeloid/lymphoid neoplasm with ETV6::FLT3 fusion with a nodal presentation without asso …