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Year Number of Results
2018 1
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302 results

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Page 1
International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.
Specchio N, Wirrell EC, Scheffer IE, Nabbout R, Riney K, Samia P, Guerreiro M, Gwer S, Zuberi SM, Wilmshurst JM, Yozawitz E, Pressler R, Hirsch E, Wiebe S, Cross HJ, Perucca E, Moshé SL, Tinuper P, Auvin S. Specchio N, et al. Epilepsia. 2022 Jun;63(6):1398-1442. doi: 10.1111/epi.17241. Epub 2022 May 3. Epilepsia. 2022. PMID: 35503717 Free article.
Epilepsy syndromes beginning in childhood have been divided into three categories: (1) self-limited focal epilepsies, comprising four syndromes: self-limited epilepsy with centrotemporal spikes, self-limited epilepsy with autonomic seizures, childhood occipital visual epilepsy, a …
Epilepsy syndromes beginning in childhood have been divided into three categories: (1) self-limited focal epilepsies, comprising four syndro …
Childhood epilepsy.
Menon RN, Helen Cross J. Menon RN, et al. Lancet. 2025 Aug 9;406(10503):636-649. doi: 10.1016/S0140-6736(25)00773-1. Epub 2025 Jul 17. Lancet. 2025. PMID: 40684779 Review.
With crucial evidence-based medicine emerging on the treatment of infantile epileptic spasm syndrome, Dravet syndrome, and Lennox-Gastaut syndrome, with a focus on improving outcomes, early identification of surgically remediable epilepsies is crucial for neu …
With crucial evidence-based medicine emerging on the treatment of infantile epileptic spasm syndrome, Dravet syndrome, and Lennox- …
Neurostimulation treatments for epilepsy: Deep brain stimulation, responsive neurostimulation and vagus nerve stimulation.
Gouveia FV, Warsi NM, Suresh H, Matin R, Ibrahim GM. Gouveia FV, et al. Neurotherapeutics. 2024 Apr;21(3):e00308. doi: 10.1016/j.neurot.2023.e00308. Epub 2024 Jan 4. Neurotherapeutics. 2024. PMID: 38177025 Free PMC article. Review.
For DBS, the most promising therapeutic targets are the anterior and centromedian nuclei of the thalamus, with anterior nucleus DBS being used for treating focal and secondarily generalized forms of DRE and centromedian nucleus DBS being applied for treating generalized epilepsie …
For DBS, the most promising therapeutic targets are the anterior and centromedian nuclei of the thalamus, with anterior nucleus DBS being us …
Refining management strategies for Lennox-Gastaut syndrome: Updated algorithms and practical approaches.
Auvin S, Arzimanoglou A, Falip M, Striano P, Cross JH. Auvin S, et al. Epilepsia Open. 2025 Feb;10(1):85-106. doi: 10.1002/epi4.13075. Epub 2024 Dec 19. Epilepsia Open. 2025. PMID: 39700524 Free PMC article.
Lennox-Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple types of drug-resistant seizures (which must include tonic seizures) with classical onset before 8 years (although some cases with later onset
Lennox-Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple ty
Epidemiology of Developmental and Epileptic Encephalopathy and of Intellectual Disability and Epilepsy in Children.
Poke G, Stanley J, Scheffer IE, Sadleir LG. Poke G, et al. Neurology. 2023 Mar 28;100(13):e1363-e1375. doi: 10.1212/WNL.0000000000206758. Epub 2022 Dec 29. Neurology. 2023. PMID: 36581463 Free PMC article.
Cumulative incidence per 100,000 children was as follows: infantile epileptic spasms syndrome 58.2 (95% CI 45.0-75.3), epilepsy with myoclonic-atonic seizures 16.4 (95% CI 9.69-27.7), Lennox-Gastaut syndrome 13.2 (95% CI 4.1-41.9), and Dravet syndrome 5.1 (95 …
Cumulative incidence per 100,000 children was as follows: infantile epileptic spasms syndrome 58.2 (95% CI 45.0-75.3), epilepsy with myoclon …
Recent advances in pharmacotherapy for epilepsy.
Pong AW, Xu KJ, Klein P. Pong AW, et al. Curr Opin Neurol. 2023 Apr 1;36(2):77-85. doi: 10.1097/WCO.0000000000001144. Epub 2023 Feb 10. Curr Opin Neurol. 2023. PMID: 36762638 Review.
RECENT FINDINGS: Difficult-to-treat epilepsy related to conditions including tuberous sclerosis complex (TSC), Lennox Gastaut syndrome (LGS) and Dravet syndrome (DS) have been the target of recent developments. ...
RECENT FINDINGS: Difficult-to-treat epilepsy related to conditions including tuberous sclerosis complex (TSC), Lennox Gastaut
CBD in the Treatment of Epilepsy.
Borowicz-Reutt K, Czernia J, Krawczyk M. Borowicz-Reutt K, et al. Molecules. 2024 Apr 25;29(9):1981. doi: 10.3390/molecules29091981. Molecules. 2024. PMID: 38731471 Free PMC article. Review.
It has been several years since highly purified cannabidiol (CBD) was registered as a medication that can be used in children of at least 2 years of age to treat different types of seizures related to Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), and m …
It has been several years since highly purified cannabidiol (CBD) was registered as a medication that can be used in children of at least 2 …
Lennox-Gastaut Syndrome: Current Treatments, Novel Therapeutics, and Future Directions.
Nelson JA, Knupp KG. Nelson JA, et al. Neurotherapeutics. 2023 Sep;20(5):1255-1262. doi: 10.1007/s13311-023-01397-x. Epub 2023 Jun 23. Neurotherapeutics. 2023. PMID: 37353676 Free PMC article. Review.
Lennox-Gastaut syndrome is a severe drug-resistant developmental and epileptic encephalopathy with slow spike and wave on EEG (DEE-SSW) composing about 1-2% of epilepsy patients. ...
Lennox-Gastaut syndrome is a severe drug-resistant developmental and epileptic encephalopathy with slow spike and wave
Epilepsy: Epileptic Syndromes and Treatment.
Katyayan A, Diaz-Medina G. Katyayan A, et al. Neurol Clin. 2021 Aug;39(3):779-795. doi: 10.1016/j.ncl.2021.04.002. Neurol Clin. 2021. PMID: 34215386 Review.
New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development.
Perucca E, White HS, Bialer M. Perucca E, et al. CNS Drugs. 2023 Sep;37(9):781-795. doi: 10.1007/s40263-023-01025-4. Epub 2023 Aug 21. CNS Drugs. 2023. PMID: 37603261 Free PMC article. Review.
Another agent, a subcutaneously administered neuroactive peptide (NRP2945) that reportedly upregulates the expression of GABA(A) receptor alpha and beta subunits is being investigated, with Lennox-Gastaut syndrome and other epilepsies as proposed indications. …
Another agent, a subcutaneously administered neuroactive peptide (NRP2945) that reportedly upregulates the expression of GABA(A) receptor al …
302 results