Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2009 1
2016 2
2020 1
2021 1
2022 1
2023 1
2024 1
2025 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

9 results

Results by year

Filters applied: . Clear all
Page 1
TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review.
Zhang H, Zhan Q, Wang X, Gao F, Yu J, Wang J, Fu W, Wang P, Wei X, Zhang L. Zhang H, et al. Ann Hematol. 2022 Dec;101(12):2583-2600. doi: 10.1007/s00277-022-04979-5. Epub 2022 Oct 1. Ann Hematol. 2022. PMID: 36181538 Free PMC article. Review.
Among the patients in our hospital, five cases were diagnosed as acute leukemia, and one was myelodysplastic syndrome evolved to acute myeloid leukemia, harboring TLS/FUS-ERG fusion gene; all the cases were detected t(16;21)(p11;q22) translocation, and five cases sh …
Among the patients in our hospital, five cases were diagnosed as acute leukemia, and one was myelodysplastic syndrome evolved to acute myelo …
A t(16;21)(p11;q22) in Acute Myeloid Leukemia (AML) Resulting in Fusion of the FUS/TLS and ERG Genes: A Review of the Literature.
Buchanan J, Tirado CA. Buchanan J, et al. J Assoc Genet Technol. 2016;42(1):24-33. J Assoc Genet Technol. 2016. PMID: 27183148
The t(16;21) results in the TLS(FUS)-ERG fusion protein, which is believed to function as a transcriptional activator in leukemogenesis and has been demonstrated to interfere in normal pre-mRNA splicing functions of FUS/TLS. ...Herein, we summarize the cytogenetic f …
The t(16;21) results in the TLS(FUS)-ERG fusion protein, which is believed to function as a transcriptional activator in leuke …
Rare and favorable prognosis of pediatric acute lymphoblastic leukemia with TLS-ERG fusion gene: Case report with long-term follow-up and review of literature.
Li S, Huang W, Wu Y, Xu X, Liao C, Tang Y. Li S, et al. Cancer Genet. 2021 Aug;256-257:51-56. doi: 10.1016/j.cancergen.2021.04.003. Epub 2021 Apr 10. Cancer Genet. 2021. PMID: 33894645 Review.
In the study of acute myeloid leukemia (AML), TLS-ERG (also called FUS-ERG or TLS/FUS-ERG) was found to be closely associated with extramedullary disease (EMD), with very poor prognosis. ...
In the study of acute myeloid leukemia (AML), TLS-ERG (also called FUS-ERG or TLS/FUS-ERG) was found to be close …
Pathologic, cytogenetic, and molecular features of acute myeloid leukemia with megakaryocytic differentiation: A report from the Children's Oncology Group.
Chisholm KM, Smith J, Heerema-McKenney AE, Choi JK, Ries RE, Hirsch BA, Raimondi SC, Wang YC, Dang A, Alonzo TA, Sung L, Aplenc R, Gamis AS, Meshinchi S, Kahwash SB. Chisholm KM, et al. Pediatr Blood Cancer. 2023 May;70(5):e30251. doi: 10.1002/pbc.30251. Epub 2023 Feb 15. Pediatr Blood Cancer. 2023. PMID: 36789545 Free PMC article.
METHODS: Morphology, cytogenetics, and genomic sequencing were assessed in patients from Children's Oncology Group trials AAML0531 and AAML1031 with central-pathology review confirmed non-Down syndrome AMkL. The 5-year event-free survival (EFS), overall survival (OS), and …
METHODS: Morphology, cytogenetics, and genomic sequencing were assessed in patients from Children's Oncology Group trials AAML0531 and AAML1 …
Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG.
Mitsuyuki S, Shimomura Y, Mizumaki H, Yanada M, Mizuno S, Uchida N, Doki N, Ito A, Tanaka M, Nishida T, Katayama Y, Yoshihara S, Eto T, Takada S, Ota S, Toyosaki M, Hasegawa Y, Nakamae H, Kawamura K, Onizuka M, Fukuda T, Ohbiki M, Atsuta Y, Konuma T. Mitsuyuki S, et al. Leukemia. 2025 Feb;39(2):495-498. doi: 10.1038/s41375-024-02495-1. Epub 2024 Dec 10. Leukemia. 2025. PMID: 39658629 No abstract available.
Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome.
Laurent AP, Kotecha RS, Malinge S. Laurent AP, et al. Leukemia. 2020 Aug;34(8):1984-1999. doi: 10.1038/s41375-020-0854-5. Epub 2020 May 20. Leukemia. 2020. PMID: 32433508 Free PMC article. Review.
While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown. ...Here, using DS-leukemia as a paradigm, we aim to in …
While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have …
[Clinical characteristics of acute myeloid leukemia with t (16;21) (p11;q22):nine cases report and literature review].
Ouyang M, Xu LP, Wang Y, Zhu HH, Qin YZ, Lai YY, Liu YR, Jiang B, Huang XJ, Jiang H. Ouyang M, et al. Zhonghua Xue Ye Xue Za Zhi. 2016 Mar;37(3):210-5. doi: 10.3760/cma.j.issn.0253-2727.2016.03.007. Zhonghua Xue Ye Xue Za Zhi. 2016. PMID: 27033758 Free PMC article. Review. Chinese.
Immunophenotypic features showed the positive CD117, CD13, CD33 and CD34, especially CD56. 5 cases were identified as complex karyotype abnormalities, besides from t (16;21) (p11;q22). All cases could be detected TLS/FUS-ERG fusion genes. 9 cases acquired complete r …
Immunophenotypic features showed the positive CD117, CD13, CD33 and CD34, especially CD56. 5 cases were identified as complex karyotype abno …
Detection of FUS-ERG chimeric transcript in two cases of acute myeloid leukemia with t(16;21)(p11.2;q22) with unusual characteristics.
Kim J, Park TS, Song J, Lee KA, Hong DJ, Min YH, Cheong JW, Choi JR. Kim J, et al. Cancer Genet Cytogenet. 2009 Oct 15;194(2):111-8. doi: 10.1016/j.cancergencyto.2009.06.010. Cancer Genet Cytogenet. 2009. PMID: 19781443
Reciprocal t(16;21)(p11;q22) is a rare chromosomal abnormality in acute myeloid leukemia (AML). The chimeric transcript FUS-ERG formed by this translocation which causes the replacement of RNA-binding domain of FUS (alias TLS) with the DNA-binding domain of ERG, and …
Reciprocal t(16;21)(p11;q22) is a rare chromosomal abnormality in acute myeloid leukemia (AML). The chimeric transcript FUS-ERG …
[AML(M7) associated with t(16;21)(p11;q22) showing relapse after unrelated bone marrow transplantation and disappearance of TLS/FUS-ERG mRNA].
Fukushima Y, Fujii N, Tabata Y, Nishimura Y, Fusaoka T, Yoshihara T, Tsunamoto K, Kasubuchi Y, Morimoto A, Hibi S, Taketani K, Hayashi Y, Imashuku S. Fukushima Y, et al. Rinsho Ketsueki. 2001 Jun;42(6):502-6. Rinsho Ketsueki. 2001. PMID: 11505530 Review. Japanese.
During hematological remission before U-BMT, the TLS/FUS-ERG chimeric transcript of t(16;21)(p11;q22) was consistently detectable as minimal residual disease (MRD) by RT-PCR. ...
During hematological remission before U-BMT, the TLS/FUS-ERG chimeric transcript of t(16;21)(p11;q22) was consistently detecta …