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FOXM1-Cx31 Axis Drives Pancreatic Cancer Stem Cell-Like Properties and Chemoresistance.
Chen Y, Sun Q, Zou Q, Zhu X, Wen T, Li X, Li S, He J, Wei F, Xie K. Chen Y, et al. Mol Carcinog. 2025 Mar;64(3):565-579. doi: 10.1002/mc.23870. Epub 2025 Jan 6. Mol Carcinog. 2025. PMID: 39757875
Pancreatic cancer is a highly lethal malignancy with few effective treatment options. Connexin 31 (Cx31) is a membrane protein capable of forming hexameric channels to facilitate the exchange of metabolites and signaling molecules. ...The correlation between …
Pancreatic cancer is a highly lethal malignancy with few effective treatment options. Connexin 31 (Cx31) is a membrane …
A rare missense mutation in GJB3 (Cx31G45E) is associated with a unique cellular phenotype resulting in necrotic cell death.
Easton JA, Albuloushi AK, Kamps MAF, Brouns GHMR, Broers JLV, Coull BJ, Oji V, van Geel M, van Steensel MAM, Martin PE. Easton JA, et al. Exp Dermatol. 2019 Oct;28(10):1106-1113. doi: 10.1111/exd.13542. Epub 2018 May 10. Exp Dermatol. 2019. PMID: 29570224
Erythrokeratodermia variabilis et progressiva (EKV-P) is caused by mutations in either the GJB3 (Cx31) or GJB4 genes (Cx30.3). We identified a rare GJB3 missense mutation, c.134G>A (p.G45E), in two unrelated patients and investigated its cellular characteristics. ...WT- …
Erythrokeratodermia variabilis et progressiva (EKV-P) is caused by mutations in either the GJB3 (Cx31) or GJB4 genes (Cx30.3). We ide …
31 results