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Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.
van Dongen JJ, Langerak AW, Brüggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F, Schuuring E, García-Sanz R, van Krieken JH, Droese J, González D, Bastard C, White HE, Spaargaren M, González M, Parreira A, Smith JL, Morgan GJ, Kneba M, Macintyre EA. van Dongen JJ, et al. Leukemia. 2003 Dec;17(12):2257-317. doi: 10.1038/sj.leu.2403202. Leukemia. 2003. PMID: 14671650 Review.
This has resulted in 107 different primers in only 18 multiplex PCR tubes: three VH-JH, two DH-JH, two Ig kappa (IGK), one Ig lambda (IGL), three TCR beta (TCRB), two TCR gamma (TCRG), one TCR delta (TCRD), three BCL1-Ig heavy chain (IGH), and one BCL2-IGH. ...In pa …
This has resulted in 107 different primers in only 18 multiplex PCR tubes: three VH-JH, two DH-JH, two Ig kappa (IGK), one Ig lambda …
BCL2 and MYC dual-hit lymphoma/leukemia.
Tomita N. Tomita N. J Clin Exp Hematop. 2011;51(1):7-12. doi: 10.3960/jslrt.51.7. J Clin Exp Hematop. 2011. PMID: 21628855 Free article. Review.
Translocation of the BCL2 gene on the chromosome band 18q21.3 results in consistent expression of the Bcl2 protein, an apoptosis inhibitor. BCL2 usually translocates to the immunoglobulin (IG) heavy chain (IGH) gene as t(14;18)(q32;q21.3) and rarely to IG lig …
Translocation of the BCL2 gene on the chromosome band 18q21.3 results in consistent expression of the Bcl2 protein, an apoptos …
Plasticity in Classical Hodgkin Composite Lymphomas: A Systematic Review.
Trecourt A, Donzel M, Fontaine J, Ghesquières H, Jallade L, Antherieu G, Laurent C, Mauduit C, Traverse-Glehen A. Trecourt A, et al. Cancers (Basel). 2022 Nov 19;14(22):5695. doi: 10.3390/cancers14225695. Cancers (Basel). 2022. PMID: 36428786 Free PMC article. Review.
This review highlights that >70% of patients with a composite lymphoma are 55 years old, with a male predominance. ...Moreover, Hodgkin cells may express specific markers of the associated lymphoma (e.g., BCL2/BCL6 for follicular lymphoma and Cyclin D1 for mantle …
This review highlights that >70% of patients with a composite lymphoma are 55 years old, with a male predominance. ...Moreover, Ho …
Primary Low-Grade B-Cell Lymphoma of Skull With Translocation Between Immunoglobulin and Interferon Regulatory Factor 4 Genes.
Nasim MM, Chalif DJ, Demopoulos AM, Brody J, Lee-Huang R, Spitzer SG, Kolitz JE, Zhang X. Nasim MM, et al. Int J Surg Pathol. 2020 May;28(3):330-335. doi: 10.1177/1066896919883013. Epub 2019 Oct 20. Int J Surg Pathol. 2020. PMID: 31631721
In this article, we report one additional case that arises from the skull and review the literature. The patient was a 69-year-old man who presented with recurrent and disabling vertigo and was found to have a 5.0 1.7 cm lesion within the left posterior parietal bone. ...F …
In this article, we report one additional case that arises from the skull and review the literature. The patient was a 69-year-old ma …